JP2003509470A5 - - Google Patents
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- Publication number
- JP2003509470A5 JP2003509470A5 JP2001524625A JP2001524625A JP2003509470A5 JP 2003509470 A5 JP2003509470 A5 JP 2003509470A5 JP 2001524625 A JP2001524625 A JP 2001524625A JP 2001524625 A JP2001524625 A JP 2001524625A JP 2003509470 A5 JP2003509470 A5 JP 2003509470A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- epitope
- administration
- combination
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000427 antigen Substances 0.000 description 15
- 102000036639 antigens Human genes 0.000 description 15
- 108091007433 antigens Proteins 0.000 description 15
- 230000037452 priming Effects 0.000 description 8
- 239000003814 drug Substances 0.000 description 6
- 210000001744 T-lymphocyte Anatomy 0.000 description 5
- 230000028993 immune response Effects 0.000 description 3
- 241000700605 Viruses Species 0.000 description 2
- 238000007918 intramuscular administration Methods 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 241000701161 unidentified adenovirus Species 0.000 description 2
- 230000002950 deficient Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9922361.2 | 1999-09-21 | ||
| GBGB9922361.2A GB9922361D0 (en) | 1999-09-21 | 1999-09-21 | Generating an immune response to an antigen |
| PCT/GB2000/003601 WO2001021201A2 (en) | 1999-09-21 | 2000-09-20 | Use of replication-deficient adenoviral vector to boost cd8+ t cell immune response to antigen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003509470A JP2003509470A (ja) | 2003-03-11 |
| JP2003509470A5 true JP2003509470A5 (https=) | 2007-10-18 |
Family
ID=10861351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001524625A Withdrawn JP2003509470A (ja) | 1999-09-21 | 2000-09-20 | 抗原に対するｃｄ８＋ｔ細胞免疫応答を増強するための複製欠損性アデノウイルスベクターの使用 |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP1214416B1 (https=) |
| JP (1) | JP2003509470A (https=) |
| CN (1) | CN1391609A (https=) |
| AT (1) | ATE295421T1 (https=) |
| AU (1) | AU762894B2 (https=) |
| BR (1) | BR0014138A (https=) |
| CA (1) | CA2384806A1 (https=) |
| DE (1) | DE60020136T2 (https=) |
| DK (1) | DK1214416T3 (https=) |
| ES (1) | ES2241653T3 (https=) |
| GB (1) | GB9922361D0 (https=) |
| WO (1) | WO2001021201A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711957D0 (en) | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| CA2378539A1 (en) | 1999-07-06 | 2001-01-11 | Merck & Co., Inc. | Adenovirus carrying gag gene hiv vaccine |
| US6733993B2 (en) | 2000-09-15 | 2004-05-11 | Merck & Co., Inc. | Enhanced first generation adenovirus vaccines expressing codon optimized HIV1-gag, pol, nef and modifications |
| GB0118532D0 (en) * | 2001-07-30 | 2001-09-19 | Isis Innovation | Materials and methods relating to improved vaccination strategies |
| JP4654026B2 (ja) * | 2002-05-20 | 2011-03-16 | 独立行政法人科学技術振興機構 | Ｂｃｇワクチンとその利用 |
| US20080153083A1 (en) | 2003-10-23 | 2008-06-26 | Crucell Holland B.V. | Settings for recombinant adenoviral-based vaccines |
| AU2003288273A1 (en) | 2002-10-23 | 2004-05-13 | Crucell Holland B.V. | New settings for recombinant adenoviral-based vaccines |
| CN100410382C (zh) * | 2006-08-18 | 2008-08-13 | 上海交通大学医学院 | 一种可诱生细胞免疫应答的共表达载体和真核表达载体 |
| WO2008063555A2 (en) * | 2006-11-17 | 2008-05-29 | Genetronics, Inc. | Methods of enhancing immune response using electroporation-assisted vaccination and boosting |
| GB0706912D0 (en) * | 2007-04-10 | 2007-05-16 | Isis Innovation | Novel viral vaccines |
| GB0706914D0 (en) * | 2007-04-10 | 2007-05-16 | Isis Innovation | Novel adenovirus vectors |
| ES2581576T3 (es) * | 2007-09-14 | 2016-09-06 | Institut Pasteur | Polinucleótidos que permiten la expresión y la secreción de pseudovirus recombinantes que contienen epítopos extraños, su producción y utilización |
| GB0823497D0 (en) | 2008-12-24 | 2009-01-28 | Isis Innovation | Immunogenic composition and use thereof |
| EP2912183B1 (en) * | 2012-10-28 | 2020-05-06 | Bavarian Nordic A/S | Pr13.5 promoter for robust t-cell and antibody responses |
| KR20230166145A (ko) | 2017-03-15 | 2023-12-06 | 옥스포드 바이오메디카(유케이) 리미티드 | 방법 |
| KR20220082047A (ko) * | 2019-10-16 | 2022-06-16 | 캔써 리서치 테크놀로지 리미티드 | 암 치료용 벡터 |
| EP4444347A1 (en) | 2021-12-07 | 2024-10-16 | Barinthus Biotherapeutics (UK) Limited | Vaccine boost methods and compositions |
| WO2024218165A1 (en) | 2023-04-17 | 2024-10-24 | Barinthus Biotherapeutics (Uk) Limited | Hpv viral vector vaccine |
-
1999
- 1999-09-21 GB GBGB9922361.2A patent/GB9922361D0/en not_active Ceased
-
2000
- 2000-09-20 BR BR0014138-0A patent/BR0014138A/pt not_active Application Discontinuation
- 2000-09-20 CA CA002384806A patent/CA2384806A1/en not_active Abandoned
- 2000-09-20 ES ES00960857T patent/ES2241653T3/es not_active Expired - Lifetime
- 2000-09-20 DE DE60020136T patent/DE60020136T2/de not_active Revoked
- 2000-09-20 AU AU73024/00A patent/AU762894B2/en not_active Ceased
- 2000-09-20 AT AT00960857T patent/ATE295421T1/de not_active IP Right Cessation
- 2000-09-20 EP EP00960857A patent/EP1214416B1/en not_active Revoked
- 2000-09-20 EP EP05009308A patent/EP1612269A1/en not_active Withdrawn
- 2000-09-20 CN CN00815933A patent/CN1391609A/zh active Pending
- 2000-09-20 DK DK00960857T patent/DK1214416T3/da active
- 2000-09-20 JP JP2001524625A patent/JP2003509470A/ja not_active Withdrawn
- 2000-09-20 WO PCT/GB2000/003601 patent/WO2001021201A2/en not_active Ceased
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