JP2003507367A5 - - Google Patents

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Publication number
JP2003507367A5
JP2003507367A5 JP2001517501A JP2001517501A JP2003507367A5 JP 2003507367 A5 JP2003507367 A5 JP 2003507367A5 JP 2001517501 A JP2001517501 A JP 2001517501A JP 2001517501 A JP2001517501 A JP 2001517501A JP 2003507367 A5 JP2003507367 A5 JP 2003507367A5
Authority
JP
Japan
Prior art keywords
disorders
compound according
tetrahydrocyclopenta
propylamine
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001517501A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003507367A (ja
Filing date
Publication date
Priority claimed from GBGB9918962.3A external-priority patent/GB9918962D0/en
Application filed filed Critical
Publication of JP2003507367A publication Critical patent/JP2003507367A/ja
Publication of JP2003507367A5 publication Critical patent/JP2003507367A5/ja
Pending legal-status Critical Current

Links

JP2001517501A 1999-08-11 2000-08-04 インドール誘導体、その調製プロセス、インドール誘導体を含有する薬学的組成物およびその医薬適用 Pending JP2003507367A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9918962.3A GB9918962D0 (en) 1999-08-11 1999-08-11 Chemical compounds xxii
GB9918962.3 1999-08-11
PCT/GB2000/003011 WO2001012603A1 (en) 1999-08-11 2000-08-04 Indole derivatives, process for their preparation, pharmaceutical compositions containing them and their medicinal application

Publications (2)

Publication Number Publication Date
JP2003507367A JP2003507367A (ja) 2003-02-25
JP2003507367A5 true JP2003507367A5 (https=) 2007-09-27

Family

ID=10858982

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001517501A Pending JP2003507367A (ja) 1999-08-11 2000-08-04 インドール誘導体、その調製プロセス、インドール誘導体を含有する薬学的組成物およびその医薬適用

Country Status (21)

Country Link
US (1) US6706750B1 (https=)
EP (1) EP1202965B1 (https=)
JP (1) JP2003507367A (https=)
KR (1) KR100740172B1 (https=)
CN (1) CN1187330C (https=)
AR (1) AR037222A1 (https=)
AT (1) ATE279392T1 (https=)
AU (1) AU773337B2 (https=)
BR (1) BR0013307A (https=)
CA (1) CA2377646A1 (https=)
DE (1) DE60014918T2 (https=)
DK (1) DK1202965T3 (https=)
ES (1) ES2228588T3 (https=)
GB (1) GB9918962D0 (https=)
MX (1) MXPA01013235A (https=)
PE (1) PE20010574A1 (https=)
PT (1) PT1202965E (https=)
TR (1) TR200200352T2 (https=)
UY (1) UY26291A1 (https=)
WO (1) WO2001012603A1 (https=)
ZA (1) ZA200110217B (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9902047D0 (en) * 1999-01-29 1999-03-17 Cerebrus Ltd Chemical compounds XI
GB9918965D0 (en) * 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxi
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (en) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
AU2167002A (en) * 2000-10-16 2002-06-11 Hoffmann La Roche Indoline derivatives and their use as 5-ht2 receptor ligands
EP1349858B1 (en) * 2000-11-02 2008-08-27 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Agents useful for reducing amyloid precursor protein and treating demantia and methods of use thereof
US6759405B2 (en) 2000-11-03 2004-07-06 Wyeth Cycloocta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives
AR031202A1 (es) 2000-11-03 2003-09-10 Wyeth Corp Ciclopenta(b) (1,4)diazepino(6,7,1-hi) indoles y derivados
AR031199A1 (es) 2000-11-03 2003-09-10 Wyeth Corp Ciclohepta/b//1,4/diacepino/6,7,1-hi/indoles y derivados
SE0004245D0 (sv) 2000-11-20 2000-11-20 Pharmacia Ab Novel compounds and their use
NZ525699A (en) 2000-11-20 2005-03-24 Biovitrum Ab Piperazinylpyrazines compounds as antagonists of serotonin 5-HT2 receptor
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US7087636B2 (en) * 2001-12-19 2006-08-08 Bristol-Myers Squibb Company Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function
TWI312781B (en) 2002-04-25 2009-08-01 [1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
TW200307682A (en) 2002-04-25 2003-12-16 Wyeth Corp 1,2,3,4,7,8-Hexahydro-6H-[1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
TW200307540A (en) 2002-04-25 2003-12-16 Wyeth Corp [1, 4]Diazocino[7, 8, 1-hi] indole derivatives as antipsychotic and antiobesity agents
JP4460450B2 (ja) 2002-06-19 2010-05-12 ビオヴィトルム・アクチボラゲット（プブリクト） 新規化合物、その使用および製造法
WO2004063156A1 (en) * 2003-01-08 2004-07-29 Biovitrum Ab Novel indole derivates as fabp-4 inhibitors
CL2004000826A1 (es) 2003-04-25 2005-03-04 Pfizer Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129
GB0314967D0 (en) * 2003-06-26 2003-07-30 Hoffmann La Roche Piperazine derivatives
US8940896B2 (en) * 2004-03-15 2015-01-27 Ptc Therapeutics, Inc. Tetra-cyclic carboline derivatives useful in the inhibition of angiogenesis
UA92317C2 (ru) * 2004-03-15 2010-10-25 Пи-Ти-Си ТЕРАПЬЮТИКС, ИНК. Производные карболина, пригодные для ингибирования развития кровеносных сосудов
US7767689B2 (en) * 2004-03-15 2010-08-03 Ptc Therapeutics, Inc. Carboline derivatives useful in the treatment of cancer
US8076353B2 (en) * 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Inhibition of VEGF translation
US8076352B2 (en) * 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Administration of carboline derivatives useful in the treatment of cancer and other diseases
WO2006012310A2 (en) * 2004-06-25 2006-02-02 Genzyme Corporation Carbazole derivatives for treating polycystic kidney disease
JP5173190B2 (ja) 2004-08-25 2013-03-27 武田薬品工業株式会社 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
GT200500317A (es) 2004-11-05 2006-10-27 Proceso para preparar compuestos de quinolina y productos obtenidos de los mismos
CN101119717A (zh) * 2004-11-23 2008-02-06 Ptc医疗公司 用作抑制vegf产生的活性剂的取代酚
WO2006058088A2 (en) * 2004-11-23 2006-06-01 Ptc Therapeutics, Inc. Carbazole, carboline and indole derivatives useful in the inhibition of vegf production
GB2422828A (en) * 2005-02-03 2006-08-09 Hunter Fleming Ltd Tricyclic cytoprotective compounds comprising an indole residue
AR054849A1 (es) 2005-07-26 2007-07-18 Wyeth Corp Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas
EP2727585A1 (en) 2006-05-16 2014-05-07 Takeda Pharmaceutical Company Limited In-vivo screening method
EP2789338A3 (en) 2007-11-15 2015-01-14 Takeda Pharmaceutical Company Limited Condensed pyridine derivate and use thereof
EP2510949A4 (en) 2009-12-11 2013-11-13 Astellas Pharma Inc THERAPEUTICS FOR FIBROMYALGIA
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
US20210052600A1 (en) 2017-12-27 2021-02-25 Takeda Pharmaceutical Company Limited Therapeutic agents for stress urinary incontinence and incotinence of feces
WO2023114238A1 (en) * 2021-12-15 2023-06-22 Delix Therapeutics, Inc. Aryloxy psychoplastogens and uses thereof

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US2541211A (en) 1948-10-15 1951-02-13 Searle & Co Tertiary-aminoalkyl-tetrahydrocarbazoles
US2687414A (en) 1948-11-26 1954-08-24 Searle & Co Method for producing aromatic aminoalkyl amines
DE930988C (de) 1953-01-01 1955-07-28 Bayer Ag Verfahren zur Herstellung von basisch alkylierten Tetrahydrocarbazolen oder Indolen
US3151120A (en) * 1961-08-15 1964-09-29 Ciba Geigy Corp Thieno [3, 2-b] indole esters and amides
US3133930A (en) * 1961-08-15 1964-05-19 Ciba Geigy Corp Ester and amide derivatives of thieno-[3, 2-b] indole 3-carboxylic acids
US3329571A (en) 1961-10-24 1967-07-04 American Home Prod Methods for treating depression
NL133522C (https=) 1961-10-24
US3142678A (en) * 1962-01-09 1964-07-28 American Home Prod Amino substituted penthienoindoles
TW334423B (en) * 1993-10-22 1998-06-21 Hoffmann La Roche Tricyclic 1-aminoethylpyrrole-derivatives
TW270114B (https=) * 1993-10-22 1996-02-11 Hoffmann La Roche
TW403738B (en) 1994-08-12 2000-09-01 Hoffmann La Roche Tricyclic pyrazole derivatives
WO1998030548A1 (en) * 1997-01-13 1998-07-16 Yamanouchi Pharmaceutical Co., Ltd. 5-HT2c RECEPTOR AGONISTS AND AMINOALKYLINDAZOLE DERIVATIVES

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