JP2003501402A - 遺伝子治療用生成物 - Google Patents

遺伝子治療用生成物

Info

Publication number
JP2003501402A
JP2003501402A JP2001501258A JP2001501258A JP2003501402A JP 2003501402 A JP2003501402 A JP 2003501402A JP 2001501258 A JP2001501258 A JP 2001501258A JP 2001501258 A JP2001501258 A JP 2001501258A JP 2003501402 A JP2003501402 A JP 2003501402A
Authority
JP
Japan
Prior art keywords
product
gene
cells
growth factor
product according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001501258A
Other languages
English (en)
Japanese (ja)
Inventor
クリストファー・ラルフ・フランクス
ルッジェロ・デッラ・ビッタ
ノーマン・ジェイムズ・メイトランド
デイビッド・ジョナサン・ナイト
Original Assignee
バイオイノベイション・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9912807.6A external-priority patent/GB9912807D0/en
Application filed by バイオイノベイション・リミテッド filed Critical バイオイノベイション・リミテッド
Publication of JP2003501402A publication Critical patent/JP2003501402A/ja
Pending legal-status Critical Current

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Classifications

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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
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    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • A61K47/6929—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
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    • C—CHEMISTRY; METALLURGY
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Endocrinology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Nanotechnology (AREA)
  • Pain & Pain Management (AREA)
JP2001501258A 1999-06-03 2000-06-05 遺伝子治療用生成物 Pending JP2003501402A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13759299P 1999-06-03 1999-06-03
US60/137,592 1999-06-03
GBGB9912807.6A GB9912807D0 (en) 1999-06-03 1999-06-03 Novel therapies
GB9912807.6 1999-06-03
PCT/GB2000/002014 WO2000074724A2 (en) 1999-06-03 2000-06-05 Conjugates comprising cytokines and nucleic acids for treating proliferating cells

Publications (1)

Publication Number Publication Date
JP2003501402A true JP2003501402A (ja) 2003-01-14

Family

ID=26315622

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001501258A Pending JP2003501402A (ja) 1999-06-03 2000-06-05 遺伝子治療用生成物

Country Status (5)

Country Link
EP (1) EP1185304A2 (de)
JP (1) JP2003501402A (de)
AU (1) AU5088600A (de)
MX (1) MXPA01012500A (de)
WO (1) WO2000074724A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR112756A1 (es) 2017-07-11 2019-12-11 Synthorx Inc Incorporación de nucleótidos no naturales, y su método
KR20200035092A (ko) 2017-08-03 2020-04-01 신톡스, 인크. 자가면역 질환의 치료를 위한 사이토카인 접합체
TW202045208A (zh) 2019-02-06 2020-12-16 美商欣爍克斯公司 Il-2結合物及其使用方法
WO2023242844A1 (en) * 2022-06-15 2023-12-21 Ramot At Tel-Aviv University Ltd. Method and therapeutic agent for treatment of disease or disorder associated with impaired firing rate and/or mitochondrial calcium homeostasis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992020364A1 (en) * 1991-05-17 1992-11-26 Seragen, Inc. Cytokine receptor targeted molecules for treatment of meoplastic cell growth
JPH10501963A (ja) * 1994-04-15 1998-02-24 ターゲテッド ジェネティクス コーポレイション 遺伝子送達融合タンパク質
CA2221269A1 (en) * 1995-05-16 1996-11-21 Lois A. Chandler Compositions containing nucleic acids and ligands for therapeutic treatment
GB9724838D0 (en) * 1997-11-26 1998-01-21 Franks Christopher R Compositions

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