JP2003252783A5 - - Google Patents
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- Publication number
- JP2003252783A5 JP2003252783A5 JP2002227397A JP2002227397A JP2003252783A5 JP 2003252783 A5 JP2003252783 A5 JP 2003252783A5 JP 2002227397 A JP2002227397 A JP 2002227397A JP 2002227397 A JP2002227397 A JP 2002227397A JP 2003252783 A5 JP2003252783 A5 JP 2003252783A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- composition
- fraction
- phlorizin
- dihydrochalcone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 14
- 150000008442 polyphenolic compounds Chemical class 0.000 claims 5
- 235000013824 polyphenols Nutrition 0.000 claims 5
- JCPGMXJLFWGRMZ-UHFFFAOYSA-N 1-(2-hydroxyphenyl)-3-phenylpropan-1-one Chemical compound OC1=CC=CC=C1C(=O)CCC1=CC=CC=C1 JCPGMXJLFWGRMZ-UHFFFAOYSA-N 0.000 claims 4
- NGSWKAQJJWESNS-UHFFFAOYSA-N 4-coumaric acid Chemical compound OC(=O)C=CC1=CC=C(O)C=C1 NGSWKAQJJWESNS-UHFFFAOYSA-N 0.000 claims 4
- 235000011430 Malus pumila Nutrition 0.000 claims 4
- 229940126902 Phlorizin Drugs 0.000 claims 4
- PXLWOFBAEVGBOA-UHFFFAOYSA-N dihydrochalcone Natural products OC1C(O)C(O)C(CO)OC1C1=C(O)C=CC(C(=O)CC(O)C=2C=CC(O)=CC=2)=C1O PXLWOFBAEVGBOA-UHFFFAOYSA-N 0.000 claims 4
- VGEREEWJJVICBM-UHFFFAOYSA-N phloretin Chemical compound C1=CC(O)=CC=C1CCC(=O)C1=C(O)C=C(O)C=C1O VGEREEWJJVICBM-UHFFFAOYSA-N 0.000 claims 4
- IOUVKUPGCMBWBT-UHFFFAOYSA-N phloridzosid Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-UHFFFAOYSA-N 0.000 claims 4
- IOUVKUPGCMBWBT-GHRYLNIYSA-N phlorizin Chemical compound O[C@@H]1[C@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-GHRYLNIYSA-N 0.000 claims 4
- 235000019139 phlorizin Nutrition 0.000 claims 4
- 241000220225 Malus Species 0.000 claims 3
- ZWTDXYUDJYDHJR-UHFFFAOYSA-N (E)-1-(2,4-dihydroxyphenyl)-3-(2,4-dihydroxyphenyl)-2-propen-1-one Natural products OC1=CC(O)=CC=C1C=CC(=O)C1=CC=C(O)C=C1O ZWTDXYUDJYDHJR-UHFFFAOYSA-N 0.000 claims 2
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 claims 2
- NGSWKAQJJWESNS-ZZXKWVIFSA-M 4-Hydroxycinnamate Natural products OC1=CC=C(\C=C\C([O-])=O)C=C1 NGSWKAQJJWESNS-ZZXKWVIFSA-M 0.000 claims 2
- DFYRUELUNQRZTB-UHFFFAOYSA-N Acetovanillone Natural products COC1=CC(C(C)=O)=CC=C1O DFYRUELUNQRZTB-UHFFFAOYSA-N 0.000 claims 2
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 claims 2
- YQHMWTPYORBCMF-UHFFFAOYSA-N Naringenin chalcone Natural products C1=CC(O)=CC=C1C=CC(=O)C1=C(O)C=C(O)C=C1O YQHMWTPYORBCMF-UHFFFAOYSA-N 0.000 claims 2
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 claims 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims 2
- 241000220222 Rosaceae Species 0.000 claims 2
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 claims 2
- 235000001368 chlorogenic acid Nutrition 0.000 claims 2
- 229940074393 chlorogenic acid Drugs 0.000 claims 2
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 claims 2
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 235000013399 edible fruits Nutrition 0.000 claims 2
- XFZJEEAOWLFHDH-NFJBMHMQSA-N procyanidin B2 Chemical compound C1([C@@H]2[C@H](O)[C@H](C3=C(O)C=C(O)C=C3O2)C=2C(O)=CC(O)=C3C[C@H]([C@H](OC3=2)C=2C=C(O)C(O)=CC=2)O)=CC=C(O)C(O)=C1 XFZJEEAOWLFHDH-NFJBMHMQSA-N 0.000 claims 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 claims 2
- PFTAWBLQPZVEMU-ZFWWWQNUSA-N (+)-epicatechin Natural products C1([C@@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-ZFWWWQNUSA-N 0.000 claims 1
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 claims 1
- XFZJEEAOWLFHDH-UHFFFAOYSA-N (2R,2'R,3R,3'R,4R)-3,3',4',5,7-Pentahydroxyflavan(48)-3,3',4',5,7-pentahydroxyflavan Natural products C=12OC(C=3C=C(O)C(O)=CC=3)C(O)CC2=C(O)C=C(O)C=1C(C1=C(O)C=C(O)C=C1O1)C(O)C1C1=CC=C(O)C(O)=C1 XFZJEEAOWLFHDH-UHFFFAOYSA-N 0.000 claims 1
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 claims 1
- 244000141359 Malus pumila Species 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 229920002350 Procyanidin B2 Polymers 0.000 claims 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 claims 1
- LUJAXSNNYBCFEE-UHFFFAOYSA-N Quercetin 3,7-dimethyl ether Natural products C=1C(OC)=CC(O)=C(C(C=2OC)=O)C=1OC=2C1=CC=C(O)C(O)=C1 LUJAXSNNYBCFEE-UHFFFAOYSA-N 0.000 claims 1
- PUTDIROJWHRSJW-UHFFFAOYSA-N Quercitrin Natural products CC1OC(Oc2cc(cc(O)c2O)C3=CC(=O)c4c(O)cc(O)cc4O3)C(O)C(O)C1O PUTDIROJWHRSJW-UHFFFAOYSA-N 0.000 claims 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 claims 1
- OXGUCUVFOIWWQJ-XIMSSLRFSA-N acanthophorin B Natural products O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OXGUCUVFOIWWQJ-XIMSSLRFSA-N 0.000 claims 1
- 230000037396 body weight Effects 0.000 claims 1
- 235000004883 caffeic acid Nutrition 0.000 claims 1
- 229940074360 caffeic acid Drugs 0.000 claims 1
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000000378 dietary effect Effects 0.000 claims 1
- LPTRNLNOHUVQMS-UHFFFAOYSA-N epicatechin Natural products Cc1cc(O)cc2OC(C(O)Cc12)c1ccc(O)c(O)c1 LPTRNLNOHUVQMS-UHFFFAOYSA-N 0.000 claims 1
- 235000012734 epicatechin Nutrition 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 229930005346 hydroxycinnamic acid Natural products 0.000 claims 1
- 235000010359 hydroxycinnamic acids Nutrition 0.000 claims 1
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 claims 1
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 150000002989 phenols Chemical class 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 229960001285 quercetin Drugs 0.000 claims 1
- 235000005875 quercetin Nutrition 0.000 claims 1
- OEKUVLQNKPXSOY-UHFFFAOYSA-N quercetin 3-O-beta-D-glucopyranosyl(1->3)-alpha-L-rhamnopyranosyl(1->6)-beta-d-galactopyranoside Natural products OC1C(O)C(C(O)C)OC1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OEKUVLQNKPXSOY-UHFFFAOYSA-N 0.000 claims 1
- QPHXPNUXTNHJOF-UHFFFAOYSA-N quercetin-7-O-beta-L-rhamnopyranoside Natural products OC1C(O)C(O)C(C)OC1OC1=CC(O)=C2C(=O)C(O)=C(C=3C=C(O)C(O)=CC=3)OC2=C1 QPHXPNUXTNHJOF-UHFFFAOYSA-N 0.000 claims 1
- OXGUCUVFOIWWQJ-HQBVPOQASA-N quercitrin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OXGUCUVFOIWWQJ-HQBVPOQASA-N 0.000 claims 1
- NGSWKAQJJWESNS-ZZXKWVIFSA-N trans-4-coumaric acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C=C1 NGSWKAQJJWESNS-ZZXKWVIFSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0202418 | 2002-02-26 | ||
| FR0202418A FR2836336B1 (fr) | 2002-02-26 | 2002-02-26 | Utilisation dans un traitement cosmetique d'une fraction phenolique riche en dihydrochalcones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003252783A JP2003252783A (ja) | 2003-09-10 |
| JP2003252783A5 true JP2003252783A5 (enExample) | 2005-10-27 |
Family
ID=27636437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002227397A Pending JP2003252783A (ja) | 2002-02-26 | 2002-08-05 | 美容処理におけるジヒドロカルコンに富むフェノール性画分の使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6805873B2 (enExample) |
| EP (1) | EP1338270B1 (enExample) |
| JP (1) | JP2003252783A (enExample) |
| AT (1) | ATE421313T1 (enExample) |
| DE (1) | DE60230961D1 (enExample) |
| DK (1) | DK1338270T3 (enExample) |
| ES (1) | ES2321164T3 (enExample) |
| FR (1) | FR2836336B1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2836336B1 (fr) * | 2002-02-26 | 2004-08-27 | Diana Ingredients | Utilisation dans un traitement cosmetique d'une fraction phenolique riche en dihydrochalcones |
| US20050186290A1 (en) * | 2003-12-10 | 2005-08-25 | L'oreal | Use of aquaglyceroporin modulators as slimming agent |
| WO2006078848A1 (en) * | 2005-01-21 | 2006-07-27 | Western Holdings, Llc | Compositions containing botanical extracts rich in phlorizin and methods for using such compositions in blood glucose modification and to affect aging |
| AT503521A1 (de) * | 2006-05-05 | 2007-11-15 | Omnica Gmbh | Verwendung eines extraktes von kiwi-frucht |
| FR2935096B1 (fr) * | 2008-08-21 | 2010-12-10 | Cooperative Agricole D Elle Et Vire | Compositions riches en acide chlorogenique, leur procede d'obtention et leur utilisation |
| AU2009319881C1 (en) * | 2008-11-26 | 2015-12-24 | Perio Sciences, Llc | Antioxidant compositions for soft oral tissue and methods of formulation and use thereof |
| CN102116772B (zh) * | 2010-09-28 | 2013-08-28 | 上海大学 | 二氢查尔酮化合物的筛选方法 |
| WO2012104145A1 (en) | 2011-01-31 | 2012-08-09 | Dsm Ip Assets B.V. | Dihydrochalcone purification process |
| CN103813723B (zh) | 2011-06-06 | 2017-03-15 | 荷兰联合利华有限公司 | 可食用组合物 |
| CA2849910A1 (en) | 2011-09-30 | 2013-04-04 | Perio Sciences, Llc | Antioxidant compositions for treatment of inflammation or oxidative damage |
| EP2596704A1 (en) * | 2011-11-28 | 2013-05-29 | Nestec S.A. | Increasing the bioavailability of hydroxycinnamic acids |
| FR2986708B1 (fr) | 2012-02-09 | 2015-09-25 | Nuxe Lab | Composition a base d'extrait de feuille de pommier pour le raffermissement de la peau |
| FR2986709B1 (fr) | 2012-02-09 | 2015-09-25 | Nuxe Lab | Composition a base d'extrait d'ecorce de pommier utilisable en cosmetique |
| FR2986707B1 (fr) | 2012-02-09 | 2015-09-25 | Nuxe Lab | Composition comprenant un extrait de jus de pomme pour le confort cutane. |
| US20170258114A1 (en) * | 2014-09-17 | 2017-09-14 | Takasago International Corporation | Flavor deterioration inhibitor |
| CN109875990A (zh) * | 2019-04-12 | 2019-06-14 | 中国农业大学 | 一种含对香豆酸的药用组合物及其应用 |
| CN117016851B (zh) * | 2023-09-11 | 2025-05-09 | 内蒙古昆明卷烟有限责任公司 | 一种烟用海棠果浸膏的制备方法、组合物及应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1427100A (fr) | 1964-12-14 | 1966-02-04 | Ile De Rech Pharma Et Therapeu | Procédé pour l'obtention d'hydroxyflavanne-3-4-diols |
| FR2092743A1 (en) | 1970-06-15 | 1972-01-28 | Aquitaine Invest Pharma | Complete extraction of total flavanol gomers from plats -peripheral - venous activity |
| GB1541469A (en) | 1976-12-01 | 1979-02-28 | Inverni Della Beffa Spa | Method of obtaining flavonolic oligomers |
| US5110801A (en) * | 1984-08-13 | 1992-05-05 | Leveen Harry H | Treatment of acne |
| US4760135A (en) * | 1984-09-06 | 1988-07-26 | University Of Kentucky Research Foundation | Phloretin and phlorizin derivative containing compounds |
| US4698360B1 (en) | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
| FR2611140B1 (fr) | 1987-02-20 | 1991-02-22 | Lamaison Jean Louis | Procede d'obtention de principes tanniques d'origine vegetale, composition cosmetologique et composition pharmaceutique contenant le principe tannique purifie obtenu selon le procede |
| IT1219732B (it) | 1988-06-28 | 1990-05-24 | Tecnofarmaci Spa | Frazioni oligomeriche procianidoliche,loro procedimento di preparazione e composizioni farmaceutiche che le contengono |
| FR2643073B1 (fr) | 1989-02-15 | 1991-08-16 | Expansion Rech Phytochimie | Procede de preparation d'extraits polyphenoliques de type flavane-3-ol purifies et extraits obtenus |
| CA1340994C (en) | 1989-09-21 | 2000-05-16 | Rudolf Edgar Dr. Falk | Treatment of conditions and disease |
| JP3018013B2 (ja) * | 1989-10-19 | 2000-03-13 | 三井農林株式会社 | α―アミラーゼ活性阻害剤 |
| CA2128293C (en) * | 1993-12-06 | 2002-09-03 | Masayuki Tanabe | Fruit polyphenols and medicinal compositions containing them |
| DE4444238A1 (de) * | 1994-12-13 | 1996-06-20 | Beiersdorf Ag | Kosmetische oder dermatologische Wirkstoffkombinationen aus Zimtsäurederivaten und Flavonglycosiden |
| JPH09291039A (ja) * | 1995-12-26 | 1997-11-11 | Suntory Ltd | プロシアニジンを有効成分とする抗肥満剤 |
| JPH09175982A (ja) * | 1995-12-28 | 1997-07-08 | Nikka Uisukii Kk | 化粧品 |
| JP4856298B2 (ja) * | 1998-06-30 | 2012-01-18 | アサヒグループホールディングス株式会社 | ポリフェノールの製造法 |
| JP4515556B2 (ja) * | 1999-05-31 | 2010-08-04 | 日本製粉株式会社 | 脂肪蓄積抑制剤、抗肥満剤、食品添加物、食品及びペットフード |
| AU5755200A (en) * | 1999-08-27 | 2001-03-26 | Joel R.L. Ehrenkranz | Method of using dihydrochalcone derivatives to block glucose transfer |
| FR2799121B1 (fr) * | 1999-10-01 | 2004-02-13 | Fabre Pierre Dermo Cosmetique | Extraits de branches de pommiers utiles en dermocosmetologie et leur procede de preparation |
| DE10018533C2 (de) | 2000-04-13 | 2002-10-31 | Herbstreith & Fox Kg Pektin Fa | Verfahren zur Gewinnung von Wertstoffen aus Nebenprodukten der Obst- und Gemüseverarbeitung |
| DE10053496A1 (de) * | 2000-10-27 | 2002-05-08 | Peter Fuerst | Zusammensetzungen enthaltend Flavonoide und Phloridzin oder Phloretin |
| FR2822466B1 (fr) * | 2001-03-23 | 2004-07-02 | Diana Ingredients | Fraction phenolique riche en phloridzine et son utilisation en tant qu'agent cosmetique, alimentaire ou nutraceutique |
| FR2836336B1 (fr) * | 2002-02-26 | 2004-08-27 | Diana Ingredients | Utilisation dans un traitement cosmetique d'une fraction phenolique riche en dihydrochalcones |
-
2002
- 2002-02-26 FR FR0202418A patent/FR2836336B1/fr not_active Expired - Lifetime
- 2002-04-04 US US10/118,521 patent/US6805873B2/en not_active Expired - Lifetime
- 2002-04-04 DE DE60230961T patent/DE60230961D1/de not_active Expired - Lifetime
- 2002-04-04 ES ES02290833T patent/ES2321164T3/es not_active Expired - Lifetime
- 2002-04-04 EP EP02290833A patent/EP1338270B1/fr not_active Revoked
- 2002-04-04 DK DK02290833T patent/DK1338270T3/da active
- 2002-04-04 AT AT02290833T patent/ATE421313T1/de active
- 2002-08-05 JP JP2002227397A patent/JP2003252783A/ja active Pending
-
2004
- 2004-10-18 US US10/967,524 patent/US7285298B2/en not_active Expired - Fee Related
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