JP2003238378A - Skin care preparation - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To obtain a skin care preparation which has excellent moisture retaining ability, slight change in moisture retaining ability, continuously has constant moisture retaining ability, removes extra sebum and stain while providing the skin with necessary moisture in a toilet soap, etc., has excellent smoothness and foaming, no greasiness in use under high humidity and excellent feel while providing the skin with necessary moisture in a cosmetic, etc. <P>SOLUTION: The skin care preparation comprises essence of Tabebuia avellanedae Lorentz, ex Grisb. or a concentrated fraction of the essence of Tabebuia avellanedae Lorentz, ex Grisb. as an active ingredient. <P>COPYRIGHT: (C)2003,JPO

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a skin external preparation that can be widely used as a soap or cosmetic.

[0002]

2. Description of the Related Art Commercially available external preparations for skin, especially toilet soaps, use designated ingredients, fragrances, and synthetic pigments that are considered to be irritating to the skin. Therefore, there is a concern about adverse effects on the skin rather than the role of the soap itself as skin care, which is to provide the skin with necessary moisture and to eliminate the tightness of the skin.

Therefore, in the conventional toilet soap, in addition to the display-designated component, the fragrance, and the synthetic pigment, which are considered to be irritating to the skin,
Many glycerin as a moisturizing agent and various other components are mixed in appropriate amounts to try to fulfill the role of skin care.

Many cosmetics as external preparations for the skin contain various moisturizers typified by glycerin and propylene glycol in order to keep the skin moist and smooth.

[0005]

However, none of the above-mentioned conventional toilet soaps can sufficiently provide the skin with the necessary moisturizing effect, and the skin's tightness cannot be almost eliminated. There was a problem that it could not fully fulfill.

Further, the above conventional cosmetics have various moisturizing agents to have a moisturizing ability to keep the skin moisturized and smooth, but it is suitable for use under high humidity. Had a problem that the sticky feeling cannot be eliminated.

Therefore, the present invention solves the problems of the above-mentioned conventional external preparations for skin, and by incorporating a specific plant extract as an active ingredient, it has an excellent moisturizing ability and, in addition, has a moisturizing ability. As a product that does not change much and always has a certain amount of moisturizing ability, it is possible to remove excess sebum and dirt while moisturizing the skin in the case of toilet soap and the like, and to provide a product that is smooth and has a good foaming property. The present invention has been made for the purpose of providing cosmetics and the like with a moisturizing property necessary for the skin, and without giving a sticky feeling even when used under high humidity.

[0008]

Therefore, the external preparation for skin of the present invention contains Avellanedae extract as an active ingredient.

Further, the external preparation for skin of the present invention may contain the Avellanedae extract concentrated fraction as an active ingredient.

The external preparation for skin of the present invention may be any one of toilet soap, face wash, bath agent and shampoo.

As the skin external preparation of the present invention, a lotion,
It may be any one of an emulsion, a beauty essence, a cream, a pack, a gel, an emulsified foundation, a scalp hair-growing material, an acne cosmetic, and a body cosmetic.

Further, when the external preparation for skin of the present invention is any one of a toilet soap, a face wash, a bath agent and a shampoo, etidronic acid may be added as an active ingredient in addition to Avellanedae extract.

The external preparation for skin of the present invention may contain red wine yeast extract or liposome dispersion in addition to Avellanedae extract.

[0014]

BEST MODE FOR CARRYING OUT THE INVENTION The Avellanedae extract contained in the external preparation for skin of the present invention means Tabebuia aberanedae (Nipponaceae) from South America Brazil.
vellanedae Lorentz, ex Gri
sb. The dried internal bark of (1) is extracted by boiling with water, and the extract is in the form of a solution or spray-dried powder extract. This Avellanedae extract is, for example, the following steps 1) to 4), steps 1) to 5) or 1).
It is manufactured through the steps of 6). The Avellanedae extract contains 2- (1-hydroxyethyl) -5-hydroxynaphtho [2,3-b] furan-4,9-dione as a useful component.

1) About 2 c of dried inner bark of Avellanedae
Cut it into chips around m. 2) Put a certain amount of treated water in the bark chips and heat at a certain temperature for a certain time. 3) A certain amount of treated water is further added according to the extraction state of the extract, and the mixture is heated at a constant temperature for a certain period of time. 4) The extracted extract is filtered with a fixed mesh and concentrated under reduced pressure to obtain a concentrated extract. 5) Concentrated extract After being subjected to an ultra-high speed centrifuge, it is concentrated under reduced pressure to obtain a highly concentrated extract (concentrated fraction). 6) Spray-dry the highly concentrated extract with a spray dryer.

In the external preparation for skin of the present invention, the Avellanedae extract is a powder or solution in an amount of 0.05.
It is preferable to mix it in an amount of up to 10.0% by weight. The compounding amount is 0.
When it is less than 05% by weight, the moisturizing ability peculiar to Avellanedae extract is not effectively exhibited, and when it is more than 10.0% by weight, stability may be affected, which is not preferable.

As the external preparation for skin of the present invention, toilet soap, face wash, bath agent, shampoo, lotion, emulsion, beauty essence, cream, pack, gel, emulsification foundation, scalp hair-growth agent, acne cosmetic agent, Examples include body cosmetics.

The etidronic acid to be added to the external preparation for skin of the present invention means 1-hydroxyethylidene-1,1-diphosphonic acid, aminotrimethylphosphonic acid, 5 sodium aminotrimethylphosphonic acid, etc., and is used as a chelating agent. It has a function of retaining foaming when the external preparation for skin is used as toilet soap, face wash, bath agent, shampoo and the like. The amount of etidronic acid to be blended is set to an appropriate amount depending on the oil and fat component as a raw material for these external preparations for skin and other components.

When the external preparation for skin of the present invention is used as a toilet soap, it can be made into a transparent toilet soap by incorporating a known clarifying agent. Examples of the clarifying agent include alcohols such as ethylene glycol, propylene glycol, butylene glycol and glycerin, and sugars such as sucrose, sucrose and granulated sugar. The white sugar and granulated sugar as the clarifying agent also have an action as a moisturizing component. In order to exert the action as the moisturizing component, it is necessary to mix 10 to 30% by weight. In addition,
When used as a transparent soap, the etidronic acid also has an effect of preventing coloration of the transparent toilet soap over time.

The red wine yeast extract and the liposome dispersion compounded in the external preparation for skin of the present invention have excellent moisturizing ability and less change in the moisturizing ability, so that the moisturizing ability can be constantly exhibited. And 0.1 to 1.0% by weight
It may be mixed.

Further, the external preparation for skin of the present invention comprises various components generally used for external preparations for skin, namely oils and fats, hydrocarbons, waxes, fatty acids, esters, alcohols, surfactants, thickeners, Moisturizers, preservatives, fragrances, pigments, other chemicals, water and the like can be added.

Examples of the oils and fats include jojoba oil, castor oil, olive oil, soybean oil, coconut oil, palm oil, cocoa oil, mink oil, turtle oil and the like.

Examples of hydrocarbons include liquid paraffin, petrolatum, microcrystalline wax, squalane and the like.

Examples of the waxes include beeswax, lanolin, carnauba wax, candelilla wax and the like.

As the fatty acid, myristic acid, palmitic acid, stearic acid, oleic acid, isostearic acid,
Examples include lauric acid and the like.

Examples of the esters include isopropyl myristate, isopropyl palmitate, butyl oleate, myristyl myristate, octyldodecyl myristate, propylene glycol monostearate, myristyl lactate, isostearyl malate, glyceryl monostearate and dichloride chloride. Stearyl dimethyl ammonium etc. are mentioned.

The above-mentioned oils and fats, hydrocarbons, waxes, fatty acids and esters are usually added in a proportion of 30% by weight or less.

As alcohols, ethanol, 1,
3-butylene glycol, propylene glycol, lauryl alcohol, cetanol, stearyl alcohol,
Examples include oleyl alcohol. Alcohol is
It is usually blended in a proportion of 25% by weight or less.

Examples of the surfactant include glycerin fatty acid esters, sorbitan fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene alkyl ethers, coconut oil fatty acid monoethanolamide and polyoxy. Ethylene hydrogenated castor oil, sodium lauryl sulphate, pyroglutamic acid isostearic acid polyoxyethylene glyceryl, sodium alkylbenzene sulfonate, polyoxyethylene stearyl ether, dialkylsulfosuccinic acid, cetylpyridinium bromide, -n-octadecyltrimethylammonium chloride, monoalkylphosphoric acid , N-acylglutamic acid, N-acylglutamine,
Sucrose fatty acid ester, polyoxyethylene sorbitan monostearate, polyoxyethylene lauryl ether sodium sulfate, polyoxyethylene reduced lanolin,
Examples include N-coconut oil fatty acid acyl taurine sodium, alkyl glycosides, tetrastearic acid polyoxyethylene pentaerythritol and the like. The surfactant is usually added in a proportion of 5% by weight or less.

Examples of the thickener include carboxyvinyl polymer, methylpolysiloxane, dextran, carboxymethylcellulose, carrageenan, hydroxypropylmethylcellulose and the like. The thickener is usually added in a proportion of 1% by weight or less.

Examples of moisturizers include glycerin, propylene glycol, 1,3-butylene glycol, pyroglutamic acid, N-acetylglutamine, N-acetylglutamine isostearyl ester, L-arginine, white wine yeast extract, seaweed extract, hyaluronic acid. , Procyanidins and the like. The moisturizer is usually added in a proportion of 25% by weight or less.

Preservatives include benzoic acid, salicylic acid,
Examples thereof include dehydroacetic acid or salts thereof, phenols of paraoxybenzoic acid ester, triclosan halocarbane, phenoxyethanol and the like. Preservatives
It is usually blended in a proportion of 0.3% by weight or less.

As the fragrance, any fragrance can be used as long as it is usually used in cosmetics, and either natural fragrance or synthetic fragrance can be used. The fragrance is usually added in a proportion of 1% by weight or less.

Examples of the pigment include iron oxide, titanium dioxide, zinc oxide, kaolin, talc and the like. The pigment is usually added in a proportion of 1% by weight or less.

Other agents include wheat germ oil, vitamin A, vitamin A B2, vitamin E, ascorbic acid-
2-magnesium phosphate, ascorbic acid-2-sodium phosphate, D-pantothenyl alcohol, dipotassium glycyrrhizinate, glutathione, UV absorbers, chelating agents, plant extracts, microbial metabolites, microbial metabolite extracts, etc. Can be mentioned. Other agents are usually blended in a proportion of 5% by weight or less.

Examples of water include tap water, mineral water, brackish water, seawater, pure water, ultrapure water, polar ice water, purified water and the like. Water is mixed in an arbitrary ratio.

[0037]

EXAMPLES Hereinafter, the skin external preparation of the present invention will be described in detail based on examples. (Example 1) To make the external preparation for skin of the present invention into a cosmetic soap, sodium hydroxide is added to animal and vegetable oils and fats (for example, animal and vegetable oils and fats in which beef tallow: coconut oil is mixed at 7: 3) to saponify the soap base. In the manufacturing process, Avellanedae extract and glycerin as a moisturizer, etidronic acid as a chelating agent, sucrose and isopropanol as a clarifying agent, and purified water are added in appropriate amounts. Next, these are heated, uniformly stirred and mixed, then put into a mold, molded into a cylinder, and naturally cooled. Then, after natural cooling, the surface is cut to trim the cut surface, laid at room temperature for 2 months, soaked in hot water, wiped in the surface, stamped and molded, and wiped to finish the surface. , The product of the following ingredients.

(Components) Soap matrix 80.3 parts Avellanedae extract 0.5 parts Glycerin 3.0 parts Etidronic acid 0.2 parts Sucrose 16.0 parts Isopropanol * 0 parts Purified water * 0 parts (* Isopropanol and purified water are , It doesn't evaporate when the product is finished.)

Using the toilet soap obtained in Example 1 above,
For normal, dry, oily, and partially dry or oily monitors, you can use them as follows depending on the condition of the skin on each monitor (feeling of lack of tightness and moistness) and gloss of the skin. Various evaluation results were obtained. Table 1 shows the evaluation results
~ 4.

Monitor age structure and skin quality: 62 people with normal skin in their 20s to 80s, 75 people with dry skin in their 20s to 70s, 20 people with oily skin in their 20s to 60s 34 people with partially dry and oily skin in their 20s to 60s Method: Use for bathing every day for about 3 months Evaluation: Very good and good for lack of tension, moistness, and gloss of skin There are 5 grades: normal, bad, and very bad.

[0041]

[Table 1]

[0042]

[Table 2]

[0043]

[Table 3]

[0044]

[Table 4]

As can be seen from Tables 1 to 4 above, the lack of a feeling of tightness in each skin monitor was about 58 to 7
As a result of 0% being very good and good, and about moist feeling, about 56 to 70% being very good and good,
Regarding the skin gloss, about 40 to 60% was very good, and the result was evaluated as good.

Furthermore, about 60% of all the monitors have no feeling of tightness, which is very good, and about 61% of the feeling of moistness is very good, which is good. Regarding gloss, about 43% was a very good result.

(Example 2) A mixture (A) having the following formulation, which was uniformly dissolved by heating in purified water, was added and stirred, and then at 60 ° C.
The formulation (B) of the following formulation that has been dissolved and kept warm in advance by the above
Is gradually added to make a uniform solution. Then, the compound (C) having the following formulation was added and dissolved to prepare a moisture lotion.

[0048]   (Prescription)   (A) Methyl paraben (preservative) 0.1 part           1,3-butylene glycol 2.0 parts           Glycerin 2.0 parts   (B) Polyoxyethylene hydrogenated castor oil 0.5 parts           Dl-α-tocopherol acetate 0.05 part   (C) 0.1 part of dipotassium glycyrrhetinate           Trehalose 0.1 part           Avellanedae extract 0.5 parts   Prepared so that the total amount of purified water is 100

Example 3 A compound (A) having the following formulation, which was heated to 80 ° C. and uniformly dissolved, was heated and dissolved in advance at 80 ° C.
While slowly adding the compound (B) having the following formulation, with stirring,
An emulsion was created. Then, after adding the compound (C) of the following formulation which was uniformly dispersed in advance and heated to 50 ° C. and uniformly mixed, the compound (D) of the following formulation was added and stirring was terminated at 30 ° C. to obtain emollient milk. Prepared.

[0050]   (Prescription)   (A) Liquid paraffin 2.0 parts           Squalane 2.0 parts           Glyceryl tri-2-ethylhexanoate 1.0 part           Jojoba oil 1.5 parts           Stearyl alcohol 1.5 parts           Decaglyceryl monolaurate 1.5 parts           Glyceryl monostearate 1.0 part           Dl-α-tocopherol acetate 0.05 part           Butylparaben (preservative) 0.1 part   (B) Methyl paraben (preservative) 0.1 part           1,3-butylene glycol 2.0 parts           Glycerin 1.0 part           Prepared so that the total amount of purified water is 100   (C) Carboxy vinyl polymer 0.1 part           Purified water 10.0 parts   (D) 0.5 part of Avellanedae extract

Example 4 A compound (A) having the following formulation, which was heated to 80 ° C. and uniformly dissolved, was heated and dissolved in advance at 80 ° C.
While slowly adding the compound (B) having the following formulation, with stirring,
An emulsion was created. Then, the compound (C) having the following formulation was added at 40 ° C. and the stirring was completed at 30 ° C. to prepare an emollient cream.

[0052]   (Prescription)   (A) Fluid Paraffin 5.0 parts           Squalane 3.0 parts           Glyceryl tri-2-ethylhexanoate 5.0 parts           White vaseline 1.5 parts           Cetyl palmitate 1.5 parts           Stearyl alcohol 2.0 parts           Glyceryl monostearate 2.0 parts           Decaglyceryl monolaurate 3.0 parts           Dl-α-tocopherol acetate 0.05 part           Butylparaben (preservative) 0.1 part   (B) Methyl paraben (preservative) 0.1 part           1,3-butylene glycol 2.0 parts           Glycerin 2.0 parts           Prepared so that the total amount of purified water is 100   (C) Quince extract 0.5 parts           Avellanedae extract 1.0 part

Example 5 A mixture having the following formulation was prepared according to a conventional method to give a cream.

[0054]   (Prescription)           Avellanedae extract 0.5 parts           Red wine yeast extract 0.1 parts           Jojoba oil 10.0 parts           Phospholipid 0.5 parts           Glycerin fatty acid ester 2.0 parts           Higher alcohol 3.0 parts           Polyhydric alcohol fatty acid ester 0.5 part           Carboxy vinyl polymer 0.05 parts           Glycerin 7.0 parts           1,3-butylene glycol 7.0 parts           L-arginine 0.1 part           Preservative 0.5 part           Prepared so that the total amount of purified water is 100

(Sensory Test 1) Using the emollient milk of Example 3 (implemented product), a sensory test was conducted on the degree of satisfaction with respect to the effect of improving dry skin and sensitive skin by a monitor in his or her 20s to 70s. Further, the same sensory test was performed using the emollient cream (control product) obtained by removing the Avellanedae extract from the formulation of Example 3. The age structure and skin type classification of the monitors are shown in Tables 5 and 6, and the sensory test was conducted in the dry season of November. Table 7 shows the test results of the implemented product and the control product.

[0056]

[Table 5]

[0057]

[Table 6]

[0058]

[Table 7]

As shown in Table 7, about 63% of the products of the present invention were satisfied or slightly satisfied, and about 10% were slightly dissatisfied or dissatisfied. As for the control product, about 30% were satisfied or slightly satisfied, and about 32% were slightly dissatisfied or dissatisfied. Therefore, it can be said that the external preparation for skin of the present invention has an excellent effect of improving dry skin and sensitive skin.

(Sensory test 2) Using the emollient cream of Example 4 (implemented product), a sensory test was conducted on the degree of satisfaction with respect to the effect of improving dry skin and sensitive skin by monitoring in the 20s to 70s. Further, the same sensory test was conducted using the emollient cream (control product) obtained by removing the Avellanedae extract from the formulation of Example 4. The age composition of the monitor and the skin type classification are as shown in Tables 5 and 6 above,
The sensory test was conducted in the dry season in November. Table 8 shows the test results of the implemented product and the control product.

[0061]

[Table 8]

As shown in Table 8, about 65% of the implements of the present invention were satisfied or slightly satisfied, and about 7% were slightly dissatisfied or dissatisfied. As for the control product, about 24% were satisfied or slightly satisfied, and about 30% were slightly dissatisfied or dissatisfied. Therefore, it can be said that the external preparation for skin of the present invention has an excellent effect of improving dry skin and sensitive skin.

(Humidity Test) 2 g of the cream (working example) of Example 5 was applied to the upper arms of 10 monitors in their 20s to 70s, and the amount of water retained on the skin after application was measured to obtain the moisture retention. I checked Noh. Further, the moisturizing ability was examined by similarly measuring the water retention amount using a cream (control product) obtained by removing the Avellanedae extract and the red wine yeast extract from the formulation of Example 5. Table 9 shows the measurement results of the implemented product and the control product.

[0064]

[Table 9]

As shown in Table 9, the products of the present invention are:
The water content was about twice that of the control product. Therefore, it can be said that the external preparation for skin of the present invention has an extremely excellent moisturizing ability.

[0066]

EFFECTS OF THE INVENTION The external preparation for skin of the present invention has an excellent moisturizing ability, has a small change in the moisturizing ability, and has a constant moisturizing ability at all times. While applying it, it can remove excess sebum and dirt, and it becomes smooth and has a good foaming property. While providing necessary moisture to the skin in cosmetics, etc., there is no sticky feeling even when used under high humidity, It has an excellent feel.

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61K 7/00 A61K 7/00 NU W Y 7/021 7/021 7/06 7/06 7/075 7/075 7/50 7/50 F-term (reference) 4C083 AA031 AA111 AA112 AA122 AC022 AC072 AC122 AC352 AC422 AC432 AC482 AC582 AC891 AC892 AD092 AD201 AD211 AD222 AD532 AD572 AD662 CC04 CC05 CC07 CC12 CC23 CC25 CC37 CC38 DD22 DD23 DD27 DD31 DD41 DD41 EE06 EE07 EE10 EE14

Claims (7)

[Claims] 1. A skin external preparation containing Avellanedae extract as an active ingredient. 2. An external preparation for skin, comprising an Avellanedae extract concentrated fraction as an active ingredient. 3. The external preparation for skin according to claim 1 or 2, wherein the external preparation for skin is any one of toilet soap, face wash, bath agent and shampoo. 4. An external preparation for skin is lotion, emulsion, beauty essence,
The external preparation for skin according to claim 1 or 2, which is one of a cream, a pack, a gel, an emulsion foundation, a hair-growth agent for scalp, a cosmetic agent for acne, and a cosmetic agent for body. 5. The external preparation for skin according to claim 3, which contains etidronic acid. 6. The external preparation for skin according to claim 3, wherein a red wine yeast extract is blended. 7. The external preparation for skin according to claim 3, wherein a liposome dispersion is blended.