JPS6127094B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to cosmetics, nutrients, drugs and household preparations exhibiting non-Newtonian flow, and can be used, for example, in thixotropic high internal phase ratio emulsions as cosmetics, nutrients, drugs and household preparations. compositions containing such substances.

Emulsions are currently widely used in cosmetics, nutrients, medicines and household preparations. However, these emulsions are of the low or medium phase ratio type. Furthermore, it is known in the art that when the internal phase ratio exceeds 75%, it becomes unstable.

An object of the present invention is to provide a non-Newtonian composition that is stable even if it is an emulsion with an internal phase ratio of 75% or more and is suitable as cosmetics, nutritional supplements, drugs, and household preparations.

These non-Newtonian flow cosmetics, nutritionals, pharmaceuticals and household preparations are best produced by stable high internal phase ratio emulsions. High internal phase ratio emulsions exhibit very different properties from low or medium internal phase ratio emulsions. In particular, they exhibit non-Newtonian flow, exhibit a yield point phenomenon, and have a decreasing effective viscosity with shear rate. High internal phase ratio emulsions recover their high viscosity almost instantly, compared to gels that take a long time to return to their original state upon shearing.

By using the high internal phase ratio emulsions of the present invention, many advantages arise in the production of cosmetics, nutritionals, pharmaceuticals and household preparations. Finely divided solids or coarse solids are diffused into the internal phase of the high internal phase ratio emulsion and are thereby stably suspended for long periods of time. Therefore, it is possible to obtain properties that normally require thickening agents to keep the solids in suspension as well as vigorous agitation just before use, and which are stable without incorporating large amounts of immiscible substances. and it is possible to convert them into non-sedimentable properties. For example, water-based cosmetics that have pigments and are typically used for body or leg cosmetics are formed into water-in-oil, high internal phase ratio emulsions that have all the benefits of the adulterated ingredients. However, it has a soft oily outer phase of about 2% by volume in order to maintain non-sedimentation properties.

Since high internal phase ratio emulsions are already highly creamy, they do not separate during storage and therefore exhibit excellent stability without creating ultrafine particles.

Because of the inherent high viscosity of high internal phase ratio emulsions, emulsions with desired viscosity properties can be made without the addition of film-forming thickeners or gelling agents. Drugs or nutrients used orally are made in oil-in-water or water-in-oil formats. When an aqueous solution of an agent having an unpleasant taste is incorporated as an internal phase in a high internal phase ratio water-in-oil emulsion, a flexible edible oil is used therein to prevent its odor. Similarly, unpalatable oils can be used as the internal phase of oil-in-water emulsions with improved odor and mouthfeel.

"Non-Newtonian fluid" refers to a thixotropic or pseudoplastic fluid. These fluids are defined as having variable apparent viscosities as the shear rate changes. In other words, when these fluids are injected at low shear rates, they behave like highly viscous fluids. However, as the injection rate increases and at the same time the shear rate increases, the fluid assumes a "shear thin" appearance and then behaves like a fluid with low viscosity.

However, the use of emulsions, especially high internal phase ratio emulsions in which the internal phase accounts for the majority of the emulsion, is particularly well suited for this purpose.
This is because, from an economic point of view, emulsions consist mostly of inexpensive primary ingredients, thereby providing an inexpensive fluid.

The non-Newtonian fluid used in the present invention is
When no force is applied, or under low shear conditions, it behaves like a flexible solid or a highly viscous fluid, but when a moderate shear rate is applied, for example when injected into a pipe, it is not very large. When shear rates are applied, they behave like low viscosity materials. These emulsions have the main part of the emulsion as the internal phase. For example, at least about 60% by volume, in one example at least about 80% by volume, but preferably about 90% by volume.
% by volume or more and often 95% by volume or more.

Special Patent Application No. 1972-72752 (Special Publication No. 55-7298)
and Japanese Patent Application No. 47-118508 (Japanese Patent Publication No. 56-34308) describe many emulsions with high internal phase ratios. It exhibits solid properties under static conditions and fluid properties under the influence of external forces. The thixotropic emulsion of the present invention has the following advantages.

1. Non-adhesive - Does not stick to the side walls of containers, etc.

2. Viscosity - Apparent resting viscosity is greater than 1000 cps, generally 10000-100000 or more, preferably 50000-100000 cps or more.
However, under low shear, it flows with a viscosity close to that of the fluid layer. Removal of shear instantly restores the initial apparent resting viscosity. The history loop is extremely small.

3. Temperature Stability - Increased temperature does not affect viscosity until a critical stability temperature is reached at which the emulsion decomposes into its fluid components. This allows use in a wide temperature range.

4. Shear Stability - The emulsion can be subjected to repeated shear deformations without collapsing unless its critical shear point is reached. However, the critical shear point is of sufficient height for normal injection and processing operations.

5. Quality Control - In these emulsions, the absence of gel-like structure makes it easy to produce products with identical performance.

6. Solids - Emulsions flow well even when containing large amounts of solids. This is because the emulsion has a wide range between static and moderate viscosity.

Compared to high volume percent solids in a gel or slurry to make a "putty," these emulsions can suspend such solids in the internal phase and affect the "flowability" of the external phase. It can be done.

Thus, the emulsion used in the present invention is as follows.

(1) Water-in-oil emulsion (2) In (1) above, an emulsion in which an aqueous substance is used instead of water, the substance being a non-aqueous and non-oil substance such as ethylene glycol, diethylene glycol, propylene glycol, etc. Contains equol and dipropylene glycol. Therefore,
The emulsion used in the present invention is a non-oil-in-oil emulsion, and the non-oil naturally contains water.

(3) An emulsion prepared by a continuous method as described in Japanese Patent Application No. 72752/1983 (Japanese Patent Publication No. 7298/1983).

Oily and non-oily materials, emulsifiers, methods, etc. described in the above Japanese patent applications may be used to prepare the emulsions of the present invention.

The following examples are provided for illustrative purposes and are not intended to be limiting. Oxyalkylation was carried out in the general manner described in Example 1a of US Pat. No. 2,695,886.

The emulsifier that can be applied to the present invention is
72752, an oxyalkylating emulsifier. Nonoxyalkyl emulsifiers can also be used.

The following example illustrates the preparation of a thixotropic emulsion with an external oil phase and a high internal water phase.

Example 1 A 2 inch (5.08 cm) diameter Viking pump driven by a motor rotating at 805 rpm has an 8 foot (2.4 cm) diameter at its outlet.
A similar flexible hose is also attached to the inlet. The ends of these two hoses are located in a 50 gallon (189.0) open iron drum. This configuration allows the sample to be pumped out of the drum and returned to the drum.

1 gallon (3.78) of mineral oil and 1 pint (0.47)
) was mixed with the emulsifier and placed in an iron drum. The emulsifier used here was prepared by an oxyalkyl reaction between 1 part by weight of octylphenol and 0.69 part by weight of ethylene oxide. While circulating this sample with a pump, water was gradually added to the water inlet of the pump. After 15 minutes, 50 gallons (189.2
) of water was added to form a thick white jelly-like emulsion.

Example 2 Laboratory samples of emulsions were prepared using a kitchen type mixer, such as the Model C3 Kitchen Aid mixer manufactured by The Hobart Manufacturing Company.
Made using C3Kitchen Aid Mixer).
This Kitchen Aid mixer has a 1.9 (2 quart) glass mixing bowl and a wire beater with planetary motion. A typical water-in-oil type cosmetic base cream with a high internal phase ratio was patented in 1973.
72752, by the following procedure. First, 10 ml of the aqueous phase and an appropriate amount of emulsifier, usually 2 to 4 ml of emulsifier, are mixed in the mixing glass bowl of the above mixer. Gradually add the organic phase to the bowl while the mixer is running at a rotational speed scale of 2 to 6. At the initial stage, the organic phase is added little by little and the oil is mixed into the emulsifier under thorough stirring. The greater the amount of material in the bowl, the greater the mixing efficiency, allowing the subsequent organic phase to be added more quickly. The experiment is considered complete when an emulsion containing no free oil phase is obtained. Perfume oils and coloring ingredients are incorporated depending on the specific purpose. When specific active ingredients are incorporated into the oil phase, it becomes necessary to adjust the emulsifier for optimal performance. The method for selecting an emulsifier is described in the aforementioned Japanese Patent Application No. 72752-1983 (Japanese Patent Publication No. 7298-1987). For example, if a water-soluble emulsifier base oil is used, the base oil is oxyalkylated with polyethylene oxide or butylene oxide until it becomes oil-soluble. On the other hand, if an oil-soluble base oil is used, the base oil is oxyalkylated with ethylene oxide until it becomes water-soluble, and a suitable emulsifier is employed for any oxyalkylation. If desired, suitable pigments may be diffused into the aqueous phase before emulsification in order to make the product opaque and match the skin tone. Water-soluble components can be dissolved in the internal phase.

For example, specialized products are prepared as follows.

Example 3 A sunscreen cream is made according to the procedure of the previous example. For example, the external phase is composed of light mineral oil, and the light mineral oil contains an ultraviolet screening agent, dipropylene glycol salicylate, in an amount of about 0.1 to 3% by weight of the light mineral oil, and an oil-soluble oil as described in Example 1 of the Japanese patent application. The emulsifier is about 1% by weight of the light mineral oil.
~10% is dissolved. The oil-soluble emulsifier is n-
This emulsifier was prepared by mixing 1 part by weight of decanol and 1.96 parts by weight of propylene oxide, and then adding 2.61 parts by weight of ethylene oxide per 1 part by weight of n-decanol for oxyalkylation. The external phase consists of water or water containing a small amount of soft glycerin. The aqueous phase is additionally adjusted to be isotonic with human skin. The actual emulsion is made by any of the methods shown in any of the previous examples. For example, following the procedure of Example 2, the external phase is placed in a Hobart type mixer and the internal phase is added slowly with the mixer speed set at a medium level. Similarly, emulsions are produced by gradually injecting the internal phase into the inlet of the pump while circulating the external phase through the pump as described in the previous example. For industrial production, the internal and external phases are preferably introduced simultaneously into a mixing tank of a continuous emulsifier.

Example 4 In exactly the same manner as shown in Example 3, an oil-soluble neutralizing agent, diethyltoluamide, was used in an amount of about 1 to 10% by weight of the light mineral oil in place of the UV screening agent. An effective insect repellent composition was created.

Typical examples of nutritional emulsions are as follows.

Example 5 The external phase is edible oil, corn oil or salad oil.
In particular, the method, ingredient amounts and emulsifiers shown in Example 1 are used. An edible emulsifier is added to edible oil, corn oil or salad oil. The interior phase is water. This produces a high internal phase ratio water-in-oil emulsion. The emulsion produced has the general properties of a mayonnaise or salad dressing and exhibits the advantage of having a very low caloric content, making it particularly suitable for diets where regulation of caloric intake is desired. Another advantage is that water-soluble flavorings can be added to the internal phase. Also, insoluble flavorings such as mustard, turmeric root powder can be added to the aqueous phase to produce a homogeneous and non-sedimentable final product.

Example 5a External Phase Corn Oil 1 Gallon (3.78) Emulsifier (Same as Example 1)
1 pint (0.47) Internal phase water 50 gallons Example 5b External phase Corn oil 1 gallon (3.78) Emulsifier C 1 pint (0.47) Internal phase water 50 gallons Example 6 Follow the procedure of Example 2 The base cream thus obtained is made into a sweat cream by using a 15% aqueous solution of aluminum chloride hydrate as a phase. In preparing this cream, the aluminum chloride component was added to the base cream and homogenized while stirring vigorously using the Kitchen Aid mixer of Example 2.

Example 7 Base cream of Example 6, i.e. Example 2
The base cream obtained with 20% of aluminum sulfate
% aqueous solution and by using 10% by weight of the internal phase of titanium dioxide suspended therein as the internal phase.
It becomes a sweat cream. In preparing this cream, both the aluminum sulfate and titanium dioxide components were added to the base cream and homogenized while stirring vigorously using the Kitchen Aid mixer of Example 2.

Example 8 A leg cosmetic, ie "liquid stockings", is made as follows.

Add the following ingredients to the Hobart mixer of Example 2.

Light mineral oil 1 gallon (3.78) Emulsifier Emulsifier of Example 1 (emulsifier of Example 3) of Japanese Patent Application No. 1972-72752 (Japanese Patent Publication No. 55-7298) 1/4 pint (0.1175) 1/4 pint (0.1175) Emulsifier of Example 21 of Japanese Patent Publication No. 55-7298 (Emulsifier of Example 1) 1/4 pint (0.1175) Using the mixer of Example 2, stir the mixture made by stirring the following ingredients. Add gradually.

Water 8 gallons (30.24) White powder base 10 pounds (4.5Kg) Concentrated loess 1 dram (1.772g) Geranium lake 2 drams (3.544g) Example 9 Japanese Patent Application No. 1972-72752 (Japanese Patent Publication No. 55-7298)
An anhydrous hand cream is made by supplying the following ingredients to the tank as described in, for example, Example 1 above, in a ratio of 4-6 parts of external phase to 1 part of internal phase: .

External phase Odorless kerosene 6 parts by volume Diglycol oleate 2 parts by volume Emulsifier of Example 1 (emulsifier of Example 3) of Japanese Patent Application No. 1972-72752 (Japanese Patent Publication No. 55-7298) 1 part by volume -72752 (Japanese Patent Publication No. 55-7298) Emulsifier of Example 21 (emulsifier of Example 1) 1 part by volume Internal phase Water 75 parts by volume Glycerin 5 parts by volume Fragrance 10 parts by volume HIPR of the present invention (high internal phase) Emulsions are used in many cosmetic products, the most important of which can be classified into the following categories: (1) Creams, such as cold creams, vanishing creams, absorbent base creams, and creams for special purposes, such as sunscreen, hair removal, deodorization, etc.; (2) lotions (cream-like), which are used for various purposes. made for. (3) Makeup and skin cosmetics (4) Shampoo, hair waving and hair styling products (5) Shaving products (6) Toothpaste (7) Bath products (8) Toilet soaps (special products for sensitive skin) (9) Hand cleaning compositions (including industrial hand cleaners, hand washing soaps used in public toilets, etc.) (10) Nutrients such as puddings,
Pies, whipped cream products, low-calorie sheer pastes, etc.

Items (8) and (9) above are very close to the fields of medicines and items used by guards and custodians, respectively. This is not surprising given the function and behavior of emulsions in such products. Many products that may be considered primarily as cosmetics have practical value for the skin and can therefore also be classified as dermatological therapeutics. Of course, the opposite is also true.
Dermatological treatments that help restore impaired skin health and are harmless enough to be sold without a prescription can, in fact, be sold as cosmetics in cosmetic stores.

Thus, the gist of the present invention resides in the following composition. (1) A thixotropic high internal phase ratio cosmetic emulsion characterized by containing a cosmetic agent (2) A thixotropic high internal phase ratio drug emulsion characterized by containing a drug (3) Containing a cosmetic agent and a drug From (4) a thixotropic high internal phase ratio cosmetic and pharmaceutical emulsion characterized by containing a nutrient (5) a thixotropic high internal phase ratio nutritional emulsion (5) an emulsion for household preparations and public facilities A composition selected from the group consisting of:

The thixotropic high internal phase ratio emulsion according to the present invention comprises:
A stable oil-in-oil emulsion containing at least 80% by volume of a dispersed internal phase, a fluid external phase and an emulsifier, exhibiting solid properties under resting conditions, while exhibiting thixotropic properties exhibiting flow properties under the influence of external forces. and contains at least one chemical agent selected from nutritional agents, cosmetic agents, pharmaceutical agents, and agents for home and public facilities.

Whether or not skin treatment products are liked by consumers depends primarily on aesthetic factors as well as scientific factors, and the latter is often difficult to control. For example, some softeners have good ingredients but have an oily feel. Although it is desirable to increase the concentration of emollients in skin treatment formulations for performance reasons, a concomitant increase in greasiness or oiliness can reduce the marketability of the product.

However, when a softening agent is mixed into the high internal phase ratio emulsion type product of the present invention, the product softens without giving a greasy or oily feel even after application to human skin or other surfaces and drying. It has been found that it is possible to mix in agents. The present invention therefore provides a means of incorporating emollients into skin care and protection formulations without sacrificing the aesthetic feel. This is because the lotion when applied to the skin and dried has a sticky, drying, non-greasy feel.

The advantages of the present invention are found in a wide range of compositions made for skin treatment and protection. Protecting or eliminating skin dryness with softening lotions is important. Insufficient water supply from the lower epidermis,
or skin dryness or "rough skin" due to excess moisture escaping from exposed areas of the skin, or both. Excessive and continuous use of soaps removes the protective fatty layer that prevents moisture from escaping, resulting in dry skin.

Softening lotions are used to protect or treat dry skin conditions. However, emollients are oily or greasy materials, and application to the skin leaves behind a greasy or oily feel, which of course increases in proportion to the amount of emollient used. The present invention allows the use of lotions containing emollients, which quickly moisturize the skin, but which are dry and non-oily to the touch. Hand lotions containing various medicaments in addition to emollients are also made according to the present invention. Other skin treatment products are made by replacing some or all of the emollients with, for example, sunscreens or analgesics. Cosmetic manufacturers can easily imagine that many other effective lotions can be made.

When conventional emulsions are applied to the skin to form a film, the film formed is easily washed away with water. The fact that this film is easily washed away makes many skin lotions useless, such as sunscreen lotions, hand lotions, skin lotions, hair lotions, etc. This is because the film often comes into contact with water and is easily washed off by contact with water or sweat, so its effectiveness is not long-lasting.

It has been found that Takauchi phase ratio emulsions have other very strange properties. It has been found that such materials have the ability to form a relatively tacky and relatively water-resistant film on the skin and other surfaces, yet the film has a relatively dry feel.

The film formed on the skin by such emulsions, by rubbing and drying, adheres more firmly to the skin and has greater water resistance than conventional emulsions.
For example, a high internal phase ratio emulsion containing only 10% oil will adhere more firmly to the skin than a conventional emulsion containing 50% oil. For example, the 90/10 W/O emulsion of the present invention and the conventional 50/
When a 50 W/0 emulsion is applied to the skin and then washed with water, the film formed on the skin by the emulsion of the present invention is not stained by an aqueous solution of blue dye, but the film formed by the conventional emulsion is dyed blue. When washed with dye, the skin turns blue. This proves that the emulsion of the present invention forms a film that is more adhesive and has better water resistance than films made with conventional emulsions.

Many softeners are known and available. In particular, the following oil-soluble softeners are useful.
Namely, wax esters such as lanolin, spermaceti; steroid alcohols such as cholesterol, lanolin alcohols; fatty alcohols such as stearyl alcohol, cetyl alcohol, etc.; triglyceride esters (animal and vegetable oils); phospholipids such as lecithin, cephalin: Mainly mono- and di-fatty acid esters of polyhydric alcohol esters, glycols, glycerol, sorbitol and pentaerythritol: Fatty alcohol esters and esters: Hydrocarbon oils and waxes: Ethoxylated lanolin or beeswax derivatives: and silicone oils.

Other additives in addition to the softener include bactericides,
These include topical painkillers, sunscreens, artificial tanning agents, and insect repellents. The invention also encompasses the use of more than one active agent in a single product, such as the coexistence of a sunscreen and an insect repellent. Oil-soluble softeners can also be dissolved and used in "inert" oils.

A number of optional ingredients can also be included in the products of this invention. It is particularly desirable to have as wetting agents mainly polyhydric alcohols, in particular glycerol, propylene glycol and sorbitol. Other optional ingredients include skin protectants, fragrances, colorants if you want something other than a white lotion, and small amounts of alcohol.

In summary, when conventional oil-containing lotions are applied to the skin, an undesirable oily film is formed. Therefore, there is a need to create lotions that form a desirable film when applied to the skin, providing a thin, tacky, and dry feel. Despite its dry feel, the film of the present invention not only provides desirable film properties, but also has the ability to not be washed away with water. This performance is in contrast to the film formed by conventional oil lotions, which not only provide an oily feel but are also easily washed away with water.
Examples of products prepared according to the present invention are listed below, but it goes without saying that the present invention is not limited to these examples.

(1) Sunscreen lotions Sunscreen lotions are widely used to prevent sunburn. That's because they contain chemicals that block the sun's rays, which cause sunburn. These lotions, usually emulsions, when applied to the brain,
It forms an oily layer, but these layers are washed off by sweating, water bathing, etc.

When these lotions are used in a swimming pool, they not only wash off from the skin and lose their effectiveness, but also float on the surface of the pool as a soap cake, staining the pool.

On the contrary, the films formed by the emulsions of the present invention are not only dry, but because of their tackiness and water resistance, soapstock formation is eliminated or reduced.

(2) Wet cream The water-in-oil wet emulsion prepared according to the present invention has an appearance similar to that of cold cream. When applied to the skin, the water present in this emulsion not only removes surface dirt, but also forms a thin, sticky, water-resistant oily film that does not leave a dry feeling on the skin. It is intended to give. Because of its tackiness, this film forms a protective coating that prevents skin abrasion that occurs during sleep due to friction with bedding. Furthermore, the adhesive film protects the skin in contact with water and is used, for example, as a protective cream for washing or before going out.

(3) Cream Suspension Lotions prepared according to the present invention can be prepared with solids in the suspension.
For example, creams containing talc form a continuous dry film of the talc-in-oil type when applied to the skin. This product not only provides comfortable moisture to the skin, but also provides a silky feel. From a cosmetic point of view, this product provides the dull glow often required in the cosmetic field. If desired, the talc is colored. For example, the moisturizing cream of the invention can also be used as a makeup base onto which cosmetics are applied. Additionally, the dry film wet base can be used as a skin make-up base and a brown talcum emulsion can also be applied to this base. Although this method does not produce a specific color, a natural tone can be obtained. This is because talc particles are well formed into a film and cannot be clearly seen from the outside.

(4) Emulsion for pine surge The skin cream prepared according to the present invention forms a wet-dry film when applied to the skin, and when the film dries, it exhibits a cooling effect similar to that of pine surge alcohol. This product exhibits the ability to act as an alcohol pine surge agent without the drying effects that normally occur in alcohol pine surge. In addition to being a soothing pine surger, this cream also forms a protective film that is very useful when a patient remains in bed for long periods of time to prevent bed sores. This pine surgery lotion is used in hospitals and for infants. Additionally, alcoholic lotions containing talc have three advantages: cooling, film formation, and silky feel.

(5) Cleansing Baby Oil Emulsion Baby oil is emulsified in alcohol, so when the product is rubbed into an infant's skin, the alcohol acts as a cleanser to remove bacteria from the skin surface. This oil then forms a normal baby oil film. This is a unique way to use baby oil to cleanse the body at the same time.
Because alcohol removes bacteria from the skin,
This is because the next step is to form a protective coating, as mothers normally do. This product is considered a cream rather than a regular oil, but it becomes an oil when used. This product soothes infants by providing a slight cooling effect, but this action forms a protective film upon evaporation, reducing the cooling effect.

(6) Wax Creams According to the present invention, wax-containing water-in-oil emulsions have also been prepared which have a creamy appearance but form a thin film of wax on the skin when used. This film forms a film on the skin and acts as a super protective cream that protects the hands like a glove.

Furthermore, these wax emulsions can be used as brighteners for furniture, automobiles, etc., which are easily adhesive, have continuous water resistance, and can form thin films.

(7) Petrolatum Cream A water-in-petrolatum oil emulsion can be prepared that is used to form a thin, textureless film of petrolatum on the skin. In contrast to traditional petrolatum, which is oily and unpleasant, a thin drying waterproof film is one of the best as a skin protector primarily to protect against moisture. This product can be used for first aid and infant use. In contrast to conventional petrolatum, which is greasy unless diluted with water until it is no longer effective, the product of the present invention forms an effective continuous thin dry water-resistant film.

(8) Hair styling emulsions Due to current trends, water-soluble materials are used in hair styling products instead of oily products that are effective for hair. The water-in-oil emulsion of the present invention is advantageous in forming a thin film on the hair to give it a natural appearance. These oil-containing emulsions provide greater protection than currently used water-soluble films without the tackiness of oily hair products.

(9) Ice skin creams According to the present invention, novel emulsion creams are prepared. These creams form a thin continuous sticky film that is very cold when applied to the skin in the form of ice cream and contains fragrance. This is a unique cosmetic product that is sold and used in a refrigerated state.

These products are also used as a base for indulgences. For example, Chiyokolate Sunday Ice Cream, Vanilla Hua Tsuji Ice Cream,
It's fruit ice cream.

Other uses include: (10) Toothpaste (11) Acne Cream (12) Tresaderm Cream (13) Hydrogen Peroxide Cream (14) Hydrocortisone Cream (15) Anti-Sweat Cream (16) Cleaning cream (17) Lipstick (18) Denture adhesive (19) PAM type non-adhesive emergency food (20) Many foods, medicines, cosmetics, health foods, household goods, and supplies for public facilities, etc.

All of the above mentioned perform their intended function when used and form the protective film of the present invention.

Next, the present invention will be explained in more detail with reference to the following examples, but it goes without saying that the present invention is not limited to these examples.

A water-in-oil emulsion is prepared as follows.

The emulsifier and oil-soluble material are dissolved in the oil phase vessel and the water-soluble material is dissolved in the water phase vessel. In order to produce the desired emulsion in the following patent application,
72752 and added to the emulsifier in appropriate proportions. The emulsion made in this way is removed and packaged.

Batch processes for water-in-oil emulsions are carried out by adding the aqueous phase to the emulsifier-containing oil phase under low shear mixing until the desired emulsion is created.

In the examples below, propylparaben and methylparaben are used as antioxidants. They are the propyl and methyl esters of parahydroxybenzoic acid, respectively.

POE(2) oleyl ester is oleic acid oxyalkylated with 2 moles of ethylene oxide. This is used as an emulsifier.

Example 10 makeup cream Forms a water-insoluble film on the skin.

Ingredients % Light mineral oil #40 5.00 POE(2) oleyl ether 5.00 70% sorbitol solution 5.00 Propylparaben 0.10 Methylparaben 0.10 Fragrance 0.05 Water 84.75 Preparation procedure 1 Weigh POE(2) oleyl ether, light mineral oil and propylparaben, and add the oil Pour into a phase container and mix. (Heat to promote solution formation.) 2. After the solution has cooled, weigh the fragrance into the oil phase container.

3. Weigh water, sorbitol, and methylparaben and mix in the water phase container. (Heat to promote solution formation.) 4 Emulsify to form W/O emulsion. (W/O means water-in-oil type.) Example 11 Cosmetic cream Forms a water-insoluble film on the skin.

Ingredients % Light mineral oil #40 2.50 POE(2) oleyl ether 2.50 70% sorbitol solution 2.50 Propylparaben 0.05 Methylparaben 0.10 Fragrance 0.05 Water 92.30 Preparation procedure 1 Weigh POE(2) oleyl ether, light mineral oil and propylparaben, and add the oil Pour into a phase container and mix. (Heat to promote solution formation.) 2. After the solution has cooled, weigh the fragrance into the oil phase container.

3. Weigh water, sorbitol, and methylparaben and mix in the water phase container. (Heat to promote solution formation.) 4 Emulsify to form W/O emulsion.

Example 12 makeup cream Forms a water-insoluble film on the skin.

Ingredients % Light mineral oil #40 1.25 POE(2) oleyl ether 1.25 70% sorbitol solution 1.25 Propylparaben 0.03 Methylparaben 0.10 Fragrance 0.05 Water 96.07 Preparation procedure 1 Weigh POE(2) oleyl ether, light mineral oil and propylparaben, and add the oil Pour into a phase container and mix. (Heat to promote solution formation.) 2. After the solution has cooled, weigh the fragrance into the oil phase container.

3. Weigh water, sorbitol, and methylparaben and mix in the water phase container. (Heat to promote solution formation.) 4 Emulsify to form W/O emulsion.

Example 13 Sunscreen Cream A sunscreen agent is mixed into a water-resistant film that does not fall off due to bathing or sweating.

Ingredients % Light mineral oil #40 5.00 POE(2) oleyl ether 5.00 Aluminum paradimethylaminobenzoate (sunlight shielding agent) 2.00 Silicone oil (dimethylsiloxane 100CS) 1.00 Propylparaben 0.10 Methylparaben 0.10 Fragrance 0.05 Water 86.75 Preparation procedure 1 POE( 2) Oleyl ether, mineral oil, silicone oil, aluminum paradimethylaminobenzoate,
and propylparaben are weighed into the oil phase container and mixed to form a solution. (By heating,
This operation must be facilitated and thoroughly agitated to keep the silicone oil uniformly suspended. ) 2 Once the oil phase container has cooled, add flavoring.

3. Weigh water and methylparaben and mix in a water phase container. (Heat to facilitate solution creation.) 4 Emulsify to form W/O emulsion.

Example 14 Hydrocortisone Cream The cream holds hydrocortisone in a non-greasy, water-resistant film that is absorbed into the skin.

Ingredients % POE(2) oleyl ether 5.0 Propylene glycol 5.0 D'Avrille petrolatum 2.5 Light mineral oil #40 2.5 Hydrocortisone-17-valerate 0.5 Propylparaben 0.1 Methylparaben 0.1 Fragrance 0.1 Water 84.2 Preparation procedure 1 POE(2) oleyl ether, Weigh the mineral oil, petrolatum, and propylparaben into the oil phase container and mix to make the solution. (Heat to accelerate solution creation.) 2. Once the oil phase container has cooled, add the fragrance.

3. Weigh the water, propylene glycol, and methylparaben into the aqueous phase container and mix to create the solution. (Heat to facilitate solution creation.) 4. Emulsify to form a W/O emulsion.

5. Add hydrocortisone to the emulsion and mix until homogeneous using an auxiliary mixer.

Example 15 Cosmetic Cream with Silicone Resin A water-insoluble film is formed to protect and moisturize the skin.

Ingredients % Light mineral oil #40 5.00 Dimethylsiloxane oil 100C.S. 3.00 POE(2) oleyl ether 5.00 70% sorbitol solution 5.00 Propylparaben 0.10 Methylparaben 0.10 Fragrance 0.05 Water 81.75 Preparation procedure 1 Mix mineral oil, silicone oil, and propylparaben with oil Mix together in a phase vessel. Heat to accelerate solution creation.

2. After cooling the oil phase container, add fragrance.

3. Mix sorbitol, methylparaben, and water together in a water phase container. Heat to accelerate solution creation.

4 Emulsify to produce a W/O emulsion.

Example 16 Hair Cream Forms a non-greasy, light continuous film on the hair.

Ingredients % Light mineral oil #40 5.00 POE(2) oleyl ether 5.00 70% sorbitol solution 5.00 Propylparaben 0.10 Methylparaben 0.10 Fragrance 0.05 Water 84.75 Preparation procedure 1 Weigh POE(2) oleyl ether, mineral oil and propylparaben, and prepare the oil phase. Mix in a container. (Heat to promote solution formation.) 2. After the solution has cooled, weigh the fragrance into the oil phase container.

3. Weigh water, sorbitol, and methylparaben and mix in the water phase container. (Heat to facilitate solution creation.) 4 Emulsify to form W/O emulsion.

Example 17 Hair Cream Forms a non-greasy, light continuous film on the hair.

Ingredients % Light mineral oil #40 2.50 POE(2) oleyl ether 25.0 70% sorbitol solution 2.50 Propylparaben 0.05 Methylparaben 0.10 Fragrance 0.05 Water 92.30 Preparation procedure 1 Weigh POE(2) oleyl ether, light mineral oil and propylparaben, and add the oil Pour into a phase container and mix. (Heat to promote solution formation.) 2. After the solution has cooled, weigh the fragrance into the oil phase container.

3. Weigh water, sorbitol, and methylparaben and mix in the water phase container. (Heat to promote solution formation.) 4 Emulsify to form W/O emulsion.

Example 18 Hair Cream Forms a non-greasy, light continuous film on the hair.

Ingredients % Light mineral oil #40 1.25 POE(2) oleyl ether 1.25 70% sorbitol solution 1.25 Propylparaben 0.03 Methylparaben 0.10 Fragrance 0.05 Water 96.07 Preparation procedure 1 Weigh POE(2) oleyl ether, light mineral oil and propylparaben, and add the oil Pour into a phase container and mix. (Heat to promote solution formation.) 2. After the solution has cooled, measure the fragrance into the oil phase container.

3. Weigh water, sorbitol, and methylparaben and mix in the water phase container. (Heat to facilitate solution creation.) 4 Emulsify to form W/O emulsion.

Example 19 Talc Cream Talc powder is contained in a water-insoluble film that protects and moisturizes the skin as well as imparting a silky "talc feel".

Ingredients % Light mineral oil #40 2.50 White fondoline petrolatum 2.50 POE(2) oleyl ether 5.00 Propylparaben 0.10 Fragrance 0.05 Talc powder 20.00 Water 64.75 Propylene glycol 5.00 Methylparaben 0.10 Preparation procedure 1 Mineral oil, petrolatum, POE(2), and propyl The parabens are mixed together in the oil phase container. Heat to promote solution formation.

2. After the oil phase container has cooled, add fragrance.

3. Mix propylene glycol, water, and methylparaben together in a water phase vessel. Heat to accelerate solution creation.

4 Emulsify to form a W/O emulsion.

5 Add talc powder to the emulsion and mix until uniform.

Example 20 Petrolatum Cream Forms a thick, durable, water-resistant film on hands and other skin for washing dishes and other strenuous tasks. This coating is not greasy.

Ingredients % White fondoline petrolatum 2.50 POE(2) oleyl ether 5.00 Light mineral oil #40 2.50 Glycerin 10.00 Propylparaben 0.10 Methylparaben 0.10 Fragrance 0.05 Water 79.75 Preparation procedure 1 Add petrolatum, POE(2), oil, and propylparaben to the oil phase Mix in a container. Heating accelerates solution creation.

2. After the oil phase container has cooled, add fragrance.

3. Mix glycerin, water, and methylparaben in a water phase container. Heating accelerates solution creation.

4 Emulsify to form a W/O emulsion.

Example 21 TRESERDERM Cream This veterinary drug for preventing pinna ear infections can be applied as a thick film without shedding or washing away.

Ingredients % Light mineral oil 5.0 POE(2)oleyl ether 5.0 Treserderm 45.0 Water 45.0 Creation steps 1. Mix mineral oil and POE(2) in an oil phase container.

2. Mix Tresadam and water in a water phase container.

3 Emulsify to form a W/O emulsion.

Example 22 Wax Cosmetic Cream Forms a durable, non-greasy, water-resistant film on the skin. It is mineral oil free, but has isopropyl myristate, wax and glycerin emollients to protect and moisturize the skin.

Ingredients % POE(2) oleyl ether 5.0 Isopropyl myristate 3.0 Witco wax ×-145 2.0 Glycerin 5.0 Water 84.7 Fragrance 0.01 Propylparaben 0.1 Methylparaben 0.1 Preparation procedure 1 POE(2), IPM, wax and propylparaben Mix and heat to create a homogeneous solution in the oil phase vessel.

2. Mix and heat glycerin, water, and methyl paraben in a water phase container to create a homogeneous solution.

3. Emulsify to make W/O emulsion.

4. Cool the emulsion, add perfume and mix with an auxiliary mixer.

Example 23 Wax Polish A hard wax film is formed by a creamy thick emulsion containing 80% water. Use a light buff to remove stains and polish.

Ingredients % Deodorized kerosene 14.0 Creamer “67” wax (manufactured by Petrolite Corporation)
5.0 POE(2) Oleyl Ether 1.0 Water 80.0 Preparation Procedure 1 Mix kerosene, wax, and POE(2) together and heat until the oil phase container is homogeneous.

2. Heat so that both phases are at the same temperature.

3 Emulsify to form a W/O emulsion.

Example 24 Silicone Resin Polish A durable silicone resin overcoat is formed from a special silicone oil. This high-class cream costs 90
% water and does not require buffing to impart shine.

Ingredients % ICI silicone oil M466 8.0 POE(2) oleyl ether 2.0 Water 90.0 Preparation procedure 1 Mix silicone oil and POE(2) together in an oil phase container.

2 Pour water into the water phase container.

3 Emulsify to create a W/O emulsion.

Example 25 Acne Cream The best ingredients against acne are benzoyl peroxide and colloidal sulfur. However, the two have not yet been combined into a stable product. This product was manufactured in stable condition.

Ingredients % Light mineral oil #40 5.00 POE(2) oleyl ether 5.00 Benzoyl peroxide 5.00 Colloidal sulfur 5.00 Water 78.80 Carboxymethylcellulose (Hercules7HF) 1.00 Methylparaben 0.10 Propyleneparaben 0.10 Preparation procedure 1 Mix mineral oil, POE(2) and propylparaben with oil Mix together in a phase vessel. Heat to accelerate solution creation.

2. Mix water, CMC, methylparaben, and benzoyl peroxide in a water phase vessel. Grind in a ball mill until the desired particle size is obtained. Add sulfur and grind in a ball mill as above.

3 Emulsify to form a W/O emulsion.

Example 26 Anti-Sweat Cream This premium cream uses the best known anti-perspirant deodorizer, aluminum hydroxychloride complex compound. This has the advantage of resulting in a non-irritating, soft, water-resistant film. This means that, unlike current commercially available products, the film will not be washed away by slight perspiration.

Ingredients % Light mineral oil #40 15.00 POE(2) oleyl ether 5.00 50% solution of aluminum hydroxychloride complex compound (CHLCRHYDROL registered trademark)
40.00 Water 39.725 Methylparaben 0.10 Propylparaben 0.10 Fragrance 0.075 Preparation Procedure 1 Mix mineral oil POE(2), and propylparaben together in an oil phase container. Heat to promote solution formation.

2. Mix alcohol, methylparaben and water in a water phase vessel. Heat to accelerate solution creation.

3 Emulsify to form a W/O emulsion.

Example 27 Toothpaste This is a new idea in toothpaste.
This polishing product cleans and shines teeth and forms a water-resistant film. This gives the teeth excellent shine as well as film protection.

Ingredients % Light mineral oil USP 2.5 Mono- and diglycerides (food grade) 2.5 Sorbitol solution 70% 2.5 Dicalcium phosphate dihydrate 20.0 Peppermint oil 0.2 Chloroform 0.1 Propylparaben 0.10 Methylparaben 0.10 Water 72.0 Preparation procedure 1 Mineral oil, glycerides, and propylparaben are mixed in an oil phase vessel and heated to promote solution formation.

2 Cool the oil phase and mix in peppermint oil and chloroform.

3. Mix sorbitol, methylparaben and water together in a water phase container. Heat to accelerate solution creation.

4 Emulsify to form a W/O emulsion.

5 Add dicalcium phosphate to the emulsion,
Mix evenly with an auxiliary mixer.

Example 28 Hydrogen Peroxide Cream A premium softening cream that protects the skin is mixed with the safest known bleaching agent. As a cream, it does not run off and stays where it is applied.

Ingredients % Light mineral oil 5.0 POE(2) oleyl ether 5.0 30% hydrogen peroxide solution 10.0 Water 80.0 Preparation procedure 1 Mix mineral oil and POE(2) together in an oil phase container.

2. Mix hydrogen peroxide and water together in a water phase vessel.

3 Emulsify to form a W/O emulsion.

Example 29 Alcohol Cream This is a soft cream in which the alcohol imparts a very refreshing cooling effect without drying the skin. A waterproof film remains on the skin to protect it.

Ingredients % Light mineral oil 5.0 PEO (20) oleyl ether 5.0 Ethyl alcohol 10.0 Propyl paraben 0.1 Methyl paraben 0.1 Water 79.8 Working procedure 1 Mix mineral oil, PEO (20) and propyl paraben in an oil phase vessel.

Heat the mixture to promote dissolution of the propylparaben.

2. Mix alcohol, methylparaben and water in a water phase vessel. Heat the mixture to promote dissolution of methylparaben.

3. Prepare a W/O emulsion by emulsifying both phases.

When the skin lotion prepared in the above examples is rubbed into the skin and allowed to dry, and the film formed thereby is washed with water, such film is not colored by the aqueous solution of the water-soluble blue dye. . In contrast, in the case of similar films made from 50/50 W/O conventional emulsions, aqueous blue dye solutions stain the skin.

Any emulsifier capable of forming a high internal phase ratio emulsion can be used. Generally, the emulsion is 0.05 to 10%, for example 2 to 8
%, for example 3-7%, but preferably 4-6
Contains % emulsifier. Nonionic emulsifiers are preferred, but other suitable emulsifiers that are non-toxic, non-irritating and do not pose an odor or color hazard may be used.
Other emulsifiers include cationic, anionic, amphoteric, etc. emulsifiers. Examples of suitable emulsifiers are polyoxyethylene fatty alcohol ethers and esters,
They are ethoxylated sorbitan fatty acid esters and polyhydric alcohol fatty acid esters. Special examples of food and cosmetic emulsifiers are as follows.

Sorbitan Sequoioleate Sorbitan Monooleate Mono- and Diglycerides Glycerol Monooleate Sorbitan Trioletononyl Phenoxypolyoxyethylene Ethanol Diglycerol Monooleate Terms to describe the films formed from the high internal phase ratio emulsions of the present invention ``stickiness'', ``relatively water resistant'', and ``relatively dry feel'' are relative to films formed from conventional emulsions. However, in general, even in the case of high internal phase ratio emulsions, films formed from emulsions having less than about 80% internal phase are relatively less sticky than high internal phase ratio emulsions of about 80% or more, and It has relatively low water resistance and also has a relatively low dry feel.

The term "household and institutional supplies" refers to products used in household and institutional maintenance services, such as cleaning agents, polishing agents, disinfectants, detergents, soaps, disinfectants, bleaches, etc.

Embodiments of the present invention are listed below.

1 the non-oil is water, ethylene glycol, diethylene glycol, propylene glycol, dipropylene glycol or a mixture thereof;
The oil is a saturated hydrocarbon including mineral oil, wax, petrolatum kerosene or mixtures thereof and edible oil, and the emulsifier is polyoxyalkylene fatty alcohol ester, polyoxyalkylene ether, alcoholate polyol fatty acid ester, sesquioleate, sorbitan oleate. , mono- or diglycerides, glycerol monooleate, sorbitan trioleate,
Nonylphenoxypolyoxyethylene ethanol or diglycerol monooleate.

2 The non-oil is water and the formulation is a nutritional supplement.

3 Water is the internal phase of the emulsion.

4. The oil is corn oil or salad oil.

5. The emulsion is a cosmetic formulation, water is the internal phase of the emulsion, the cosmetic agent is a pigment, and the formulation is for leg makeup.

6 The emulsion is a cosmetic preparation, water is the internal phase of the emulsion, and the cosmetic agent is an ultraviolet absorber, talc, an aphrodisiac, a humidifier, an antiperspirant,
Rubbing alcohol or hair protectant.

7. The external phase of the emulsion is mineral oil, and an oil-soluble emollient is added to the mineral oil.

8 The internal phase of the emulsion is water with a small amount of humectant.

9 An emulsion is a cosmetic formulation, and water and alcohol form the external phase of the emulsion.

10 An emulsion is a cosmetic formulation, water is the external phase of the emulsion, and the emulsifier is dissolved in the aqueous phase.

11 The emulsion is a pharmaceutical or veterinary formulation, water is the internal phase of the emulsion, and into the emulsion hydrocortisone, tresadam, benzoyl peroxide-colloidal sulfur or analgesics are added.

12 An emulsion is a household or institutional formulation in which water is the internal phase of the emulsion and the external phase contains detergents, soaps, waxes, abrasives, bleaches, or disinfectants.

Claims (1)

[Claims] 1. An emulsion composition comprising at least 80% by volume of a dispersed internal phase, a fluid external phase, and an emulsifier, and is non-oil-in-oil, said emulsion composition being free of thickeners, stable, and quiescent. The oil has thixotropy, exhibiting solid properties under conditions, while exhibiting flow properties under external influences, and the oil is mineral oil,
1 selected from the group consisting of wax, petrolatum kerosene, mixtures of these substances and edible oils.
saturated hydrocarbons, said non-oil is water, water and ethylene glycol, water and diethylene glycol,
The emulsion composition is one selected from the group consisting of water and propylene glycol and water and dipropylene glycol, and the emulsion composition is at least one selected from the group consisting of nutritional supplements, cosmetics, pharmaceutical drugs, and drugs for home and public facilities. An emulsion composition characterized in that it contains a chemical agent.