JP2002543118A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002543118A5 JP2002543118A5 JP2000614987A JP2000614987A JP2002543118A5 JP 2002543118 A5 JP2002543118 A5 JP 2002543118A5 JP 2000614987 A JP2000614987 A JP 2000614987A JP 2000614987 A JP2000614987 A JP 2000614987A JP 2002543118 A5 JP2002543118 A5 JP 2002543118A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pioglitazone
- metformin
- pharmaceutically acceptable
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13167599P | 1999-04-29 | 1999-04-29 | |
| US60/131,675 | 1999-04-29 | ||
| PCT/US2000/011355 WO2000066102A2 (en) | 1999-04-29 | 2000-04-28 | Pentoxifylline, pioglitazone and metformin are inhibitors of formation of advanced glycation endproducts (age's) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002543118A JP2002543118A (ja) | 2002-12-17 |
| JP2002543118A5 true JP2002543118A5 (https=) | 2007-06-28 |
Family
ID=22450526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000614987A Pending JP2002543118A (ja) | 1999-04-29 | 2000-04-28 | ペントキシフィリン、ピオグリタゾンおよびメトフォルミンは、後期糖化最終生成物（ａｇｅ）の形成の阻害剤である |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20020123501A1 (https=) |
| EP (1) | EP1210087A2 (https=) |
| JP (1) | JP2002543118A (https=) |
| AU (1) | AU776162B2 (https=) |
| CA (1) | CA2371391A1 (https=) |
| WO (1) | WO2000066102A2 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7030133B2 (en) | 1999-04-05 | 2006-04-18 | City Of Hope | Inhibitors of formation of advanced glycation endproducts (AGEs) |
| US6589944B1 (en) | 1999-04-05 | 2003-07-08 | City Of Hope | Breakers of advanced glycation endproducts |
| US6787566B2 (en) * | 1999-04-05 | 2004-09-07 | City Of Hope | Breakers of advanced glycation endproducts |
| JP4481011B2 (ja) | 2002-03-05 | 2010-06-16 | トランス テック ファーマ，インコーポレイテッド | リガンドのｒａｇｅとの相互作用を阻害する単環式および二環式アゾール誘導体 |
| UA80991C2 (en) | 2002-10-07 | 2007-11-26 | Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes | |
| GB0312122D0 (en) * | 2003-05-27 | 2003-07-02 | Pharmagene Lab Ltd | Therapeutic method |
| JP4976851B2 (ja) | 2003-10-27 | 2012-07-18 | シティ・オブ・ホープ | 脂質レベルを哺乳動物において低下させる方法 |
| US20090088367A1 (en) * | 2004-05-10 | 2009-04-02 | Burnham Institute For Medical Research | Treatment of Insulin Resistance/Metabolic Syndrome to Alleviate the Risks of Dementia |
| FR2883873B1 (fr) | 2005-03-31 | 2009-07-10 | Pharmamens Sarl | Inhibiteurs d'age |
| US20080248099A1 (en) | 2005-11-11 | 2008-10-09 | Ishii Douglas N | Method for Treating Disease or Disorder of Adult Central Nervous System Associated with Tissue Shrinkage or Atrophy by Administration of Insulin |
| CN101448500A (zh) * | 2006-03-16 | 2009-06-03 | 新陈代谢解决方案开发公司 | 噻唑烷二酮类似物和糖皮质激素激动剂的组合疗法 |
| DE102007041232A1 (de) | 2007-08-30 | 2009-03-05 | Henkel Ag & Co. Kgaa | Verwendung von Sulfonylharnstoffen zur Spaltung von AGEs |
| US8563500B2 (en) | 2007-09-05 | 2013-10-22 | Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts | Methods and compounds for treating diseases caused by reactive oxygen species |
| KR101537830B1 (ko) * | 2007-09-14 | 2015-07-17 | 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 | 고혈압 치료용 티아졸리딘디온 유사체 |
| US8304441B2 (en) | 2007-09-14 | 2012-11-06 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic diseases |
| DE102007054653A1 (de) | 2007-11-14 | 2009-05-20 | Henkel Ag & Co. Kgaa | Verwendung von Thioharnstoff-Derivaten zur Spaltung von AGEs |
| ME01898B (me) | 2008-08-12 | 2014-12-20 | Zinfandel Pharmaceuticals Inc | Metoda za identifikaciju faktora rizika od alchajmerove bolesti |
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| GB2465796A (en) * | 2008-12-01 | 2010-06-02 | Bee Kang Tan | Metformin for the therapeutic use of conditions with raised serum amyloid A levels |
| US8377947B2 (en) * | 2009-03-16 | 2013-02-19 | Chien-Hung Chen | Treating alzheimer's disease and osteoporosis and reducing aging |
| ES2467923T3 (es) | 2009-09-30 | 2014-06-13 | Transtech Pharma, Llc | Derivados de imidazol substituidos para el tratamiento de la enfermedad de Alzheimer |
| RU2564661C2 (ru) | 2009-12-15 | 2015-10-10 | МЕТАБОЛИК СОЛЮШНЗ ДЕВЕЛОПМЕНТ КОМПАНИ, ЭлЭлСи | Соли тиазолидиндиона со сниженным сродством к ppar для лечения нарушений обмена веществ |
| NL1037643C2 (en) * | 2010-01-22 | 2011-07-25 | Karel Paul Bouter | Nutritional product comprising a biguanide. |
| AU2012205798B2 (en) | 2011-01-10 | 2016-02-25 | Takeda Pharmaceutical Company Limited | Methods and drug products for treating Alzheimer's disease |
| US9808434B2 (en) | 2011-01-27 | 2017-11-07 | City Of Hope | Compound for treating cancer and diabetes |
| WO2012103523A2 (en) | 2011-01-27 | 2012-08-02 | Samuel Rahbar | Novel modulators of development of adipocyte and cancer cells |
| US20150038589A1 (en) * | 2011-07-22 | 2015-02-05 | Karel Paul Bouter | Nutritional Product Comprising a Biguanide |
| KR101432246B1 (ko) * | 2011-09-20 | 2014-08-21 | 가톨릭대학교 산학협력단 | 메포민을 포함하는 자가면역질환 예방 및 치료용 조성물 |
| ES2589169B1 (es) * | 2015-05-06 | 2017-08-29 | Instituto De Investigacion Sanitaria - Fundación Jiménez Díaz | Uso de la pentoxifilina y de una composición farmacéutica para elaborar un medicamento para prevenir el envejecimiento prematuro en humanos |
| WO2019104065A1 (en) * | 2017-11-22 | 2019-05-31 | Turrinii Pharmaceutical, Llc | Anti-aging methods and compositions |
| CN114831930B (zh) * | 2022-03-28 | 2023-09-05 | 厦门大学 | 一种胶原蛋白组装眼药、制备方法及应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5100919A (en) * | 1984-03-19 | 1992-03-31 | The Rockefeller University | Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein |
| JPH062675B2 (ja) * | 1985-04-05 | 1994-01-12 | ヘキストジヤパン株式会社 | 記憶障害治療剤 |
| JPH0798794B2 (ja) * | 1987-04-01 | 1995-10-25 | 大鵬薬品工業株式会社 | タウリン型化合物 |
| US5268500A (en) | 1987-06-15 | 1993-12-07 | Montefiore Medical Center | Compound, composition and method for the reduction of lipids the modification of the affinity of hemoblogin for oxygen and the prevention of platelet aggregation |
| US5093367A (en) | 1988-06-15 | 1992-03-03 | Montefiore Medical Center | Method of synthesis and novel compounds for pharmaceutical uses |
| US4921997A (en) | 1988-06-15 | 1990-05-01 | Montefiore Medical Center | Method of synthesis and novel compounds for pharmaceutical uses |
| JP3117823B2 (ja) * | 1992-11-17 | 2000-12-18 | 鐘紡株式会社 | コラーゲン代謝賦活剤 |
| JPH0741423A (ja) * | 1993-02-24 | 1995-02-10 | Sankyo Co Ltd | 動脈硬化症治療剤 |
| US6046222A (en) * | 1993-09-15 | 2000-04-04 | Warner-Lambert Company | Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
| JPH1029942A (ja) * | 1996-04-02 | 1998-02-03 | Yoichi Ichikawa | 慢性関節リウマチ治療剤 |
| JPH10212247A (ja) * | 1996-05-31 | 1998-08-11 | Sankyo Co Ltd | 自己免疫疾患治療剤 |
| US6191154B1 (en) * | 1998-11-27 | 2001-02-20 | Case Western Reserve University | Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases |
| US6498193B2 (en) * | 1999-12-22 | 2002-12-24 | Trustees Of Dartmouth College | Treatment for complications of type 2 diabetes |
-
2000
- 2000-04-28 WO PCT/US2000/011355 patent/WO2000066102A2/en not_active Ceased
- 2000-04-28 AU AU46712/00A patent/AU776162B2/en not_active Ceased
- 2000-04-28 JP JP2000614987A patent/JP2002543118A/ja active Pending
- 2000-04-28 CA CA002371391A patent/CA2371391A1/en not_active Abandoned
- 2000-04-28 EP EP00928475A patent/EP1210087A2/en not_active Withdrawn
-
2002
- 2002-03-14 US US10/096,580 patent/US20020123501A1/en not_active Abandoned
- 2002-03-14 US US10/096,579 patent/US6693106B2/en not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002543118A5 (https=) | ||
| JP2003530346A5 (https=) | ||
| ATE124626T1 (de) | Verwendung von triclosan zur behandlung von krankheiten des gastrointestinaltraktes. | |
| CA2380068A1 (en) | Pullulan film compositions | |
| CA2452577A1 (en) | Soft capsules | |
| JP2004506009A5 (https=) | ||
| ATE289512T1 (de) | Arzneimittel zur behandlung der mucositis, stomatitis und des behcetschen syndroms | |
| BRPI0513455A (pt) | formulação para mascaramento de sabor compreendendo o fármaco em uma forma de dissolução retardada e/ou ciclodextrina em uma forma de dissolução melhorada | |
| SE8801732D0 (sv) | Ny komposition | |
| WO2008057300A2 (en) | Trpvi antagonists and uses thereof | |
| JP2000290161A5 (https=) | ||
| EP1264838A4 (en) | PROTEIN HYDROLYSATES, THEIR PRODUCTION PROCESS AND FOOD AND DRINKS CONTAINING PROTEIN HYDROLYSTS | |
| RU2005117356A (ru) | Способ подавления роста дрожжей | |
| JP2939301B2 (ja) | 経口摂取組成物 | |
| JP5053535B2 (ja) | 寝つきまたは寝起き改善用経口剤 | |
| JP2003522782A5 (https=) | ||
| JP2007514699A5 (https=) | ||
| NO20005850L (no) | Fremgangsmåte for konservering av spekeprodukt av marint råstoff | |
| RU2006109556A (ru) | Состав для детского питания | |
| WO2004004705A3 (en) | Pharmaceutical formulations for preparing drink products | |
| Babu et al. | Overview of formulation & evaluation of fast dissolving tablet: A promising tablet dosage form | |
| RU2004107655A (ru) | Композиции для регулирования аппетита и связанные с ними способы | |
| WO2006115153A1 (ja) | 肌状態改善作用を有する食品組成物 | |
| JP3140669U (ja) | タコ酒用吸盤プレート | |
| JP3238977U (ja) | 乾燥食品商品 |