JP2002542783A5 - - Google Patents
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- Publication number
- JP2002542783A5 JP2002542783A5 JP2000614395A JP2000614395A JP2002542783A5 JP 2002542783 A5 JP2002542783 A5 JP 2002542783A5 JP 2000614395 A JP2000614395 A JP 2000614395A JP 2000614395 A JP2000614395 A JP 2000614395A JP 2002542783 A5 JP2002542783 A5 JP 2002542783A5
- Authority
- JP
- Japan
- Prior art keywords
- kda
- phl
- fraction
- passed
- separated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013566 allergen Substances 0.000 description 3
- 239000012505 Superdex™ Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000002523 gelfiltration Methods 0.000 description 1
- 238000004191 hydrophobic interaction chromatography Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19918682A DE19918682A1 (de) | 1999-04-23 | 1999-04-23 | DNA-Sequenz und rekombinante Herstellung eines Graminaen-Allergens |
| DE19918682.0 | 1999-04-23 | ||
| PCT/EP2000/003259 WO2000065060A2 (de) | 1999-04-23 | 2000-04-12 | Dna-sequenz und rekombinante herstellung eines graminaen-allergens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002542783A JP2002542783A (ja) | 2002-12-17 |
| JP2002542783A5 true JP2002542783A5 (enExample) | 2010-09-09 |
| JP4588888B2 JP4588888B2 (ja) | 2010-12-01 |
Family
ID=7905749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000614395A Expired - Fee Related JP4588888B2 (ja) | 1999-04-23 | 2000-04-12 | イネ科アレルゲンのｄｎａ配列および組換え体産生 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7241450B1 (enExample) |
| EP (1) | EP1171604B1 (enExample) |
| JP (1) | JP4588888B2 (enExample) |
| CN (1) | CN1203179C (enExample) |
| AT (1) | ATE338126T1 (enExample) |
| AU (1) | AU781275B2 (enExample) |
| CA (1) | CA2370393C (enExample) |
| CZ (1) | CZ20013796A3 (enExample) |
| DE (2) | DE19918682A1 (enExample) |
| ES (1) | ES2270828T3 (enExample) |
| HU (1) | HUP0200883A2 (enExample) |
| PL (1) | PL201818B1 (enExample) |
| PT (1) | PT1171604E (enExample) |
| RU (1) | RU2238321C2 (enExample) |
| WO (1) | WO2000065060A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19939982A1 (de) | 1999-08-24 | 2001-03-01 | Merck Patent Gmbh | Verfahren zur Isolierung und Aufreinigung von Gräserpollenallergenen |
| AUPR779201A0 (en) * | 2001-09-20 | 2001-10-11 | University Of Melbourne, The | Immunotherapeutic and immunoprophylactic reagents |
| SE0200946D0 (sv) * | 2002-03-27 | 2002-03-27 | Pharmacia Diagnostics Ab | Novel Allergen |
| US7731970B2 (en) * | 2002-08-19 | 2010-06-08 | Merck Patent Gmbh | Variants of the major allergen Phl p 1 from timothy grass |
| JP4782671B2 (ja) | 2003-06-04 | 2011-09-28 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 低減したアレルギー誘発性および保持されたＴ細胞反応性を有するＰｈｌｐ５ａ誘導体 |
| DE10359351A1 (de) * | 2003-12-16 | 2005-07-21 | Merck Patent Gmbh | DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden |
| DE102004035337A1 (de) * | 2004-07-21 | 2006-03-16 | Merck Patent Gmbh | Varianten der Gruppe 1-Allergene aus Poaceae mit reduzierter Allergenität und erhaltener T-Zellreaktivität |
| EP2523684A1 (de) * | 2010-01-14 | 2012-11-21 | Merck Patent GmbH | Varianten der gruppe 6-allergene der süssgräser mit reduzierter allergenität durch mutagenese von prolinresten |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5736362A (en) * | 1990-10-26 | 1998-04-07 | The University Of Melbourne | Ryegrass pollen allergen |
-
1999
- 1999-04-23 DE DE19918682A patent/DE19918682A1/de not_active Withdrawn
-
2000
- 2000-04-12 PT PT00926876T patent/PT1171604E/pt unknown
- 2000-04-12 US US09/959,340 patent/US7241450B1/en not_active Expired - Fee Related
- 2000-04-12 EP EP00926876A patent/EP1171604B1/de not_active Expired - Lifetime
- 2000-04-12 DE DE50013400T patent/DE50013400D1/de not_active Expired - Lifetime
- 2000-04-12 CA CA2370393A patent/CA2370393C/en not_active Expired - Fee Related
- 2000-04-12 JP JP2000614395A patent/JP4588888B2/ja not_active Expired - Fee Related
- 2000-04-12 HU HU0200883A patent/HUP0200883A2/hu unknown
- 2000-04-12 CN CNB008066566A patent/CN1203179C/zh not_active Expired - Fee Related
- 2000-04-12 AU AU45477/00A patent/AU781275B2/en not_active Ceased
- 2000-04-12 PL PL356055A patent/PL201818B1/pl unknown
- 2000-04-12 ES ES00926876T patent/ES2270828T3/es not_active Expired - Lifetime
- 2000-04-12 RU RU2001130165A patent/RU2238321C2/ru not_active IP Right Cessation
- 2000-04-12 WO PCT/EP2000/003259 patent/WO2000065060A2/de not_active Ceased
- 2000-04-12 CZ CZ20013796A patent/CZ20013796A3/cs unknown
- 2000-04-12 AT AT00926876T patent/ATE338126T1/de active
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