MXPA04005767A - Formacion previa para hacer tabletas de mezclas naturales de estrogenos conjugados. - Google Patents

Formacion previa para hacer tabletas de mezclas naturales de estrogenos conjugados.

Info

Publication number
MXPA04005767A
MXPA04005767A MXPA04005767A MXPA04005767A MXPA04005767A MX PA04005767 A MXPA04005767 A MX PA04005767A MX PA04005767 A MXPA04005767 A MX PA04005767A MX PA04005767 A MXPA04005767 A MX PA04005767A MX PA04005767 A MXPA04005767 A MX PA04005767A
Authority
MX
Mexico
Prior art keywords
tabletting
formulation
natural mixtures
conjugated estrogens
solid
Prior art date
Application number
MXPA04005767A
Other languages
English (en)
Inventor
Lerch Martina
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of MXPA04005767A publication Critical patent/MXPA04005767A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invencion se relaciona con una formacion previa farmaceutica en forma de un extracto seco solido libremente fluente de mezclas naturales de estrogenos equinos conjugados. Formaciones convenientes de las mezclas naturales mencionadas de estrogeno equinos conjugados se usan para formas galenicas solidas, por ejemplo, para hacer tabletas. Los estrogenos conjugados se proporcionan para el procesamiento galenico posterior en una forma que asegura la estabilidad quimica de las hormonas y permite un procesamiento ventajoso para obtener formas galenicas solidas, por ejemplo tabletas. La invencion se refiere tambien a un metodo para la produccion de esta formacion en forma de un extracto seco.
MXPA04005767A 2001-12-14 2002-12-12 Formacion previa para hacer tabletas de mezclas naturales de estrogenos conjugados. MXPA04005767A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01129840 2001-12-14
PCT/EP2002/014104 WO2003051337A1 (de) 2001-12-14 2002-12-12 Präformulierung für die tablettierung von natürlichen gemischen konjugierter oestrogene

Publications (1)

Publication Number Publication Date
MXPA04005767A true MXPA04005767A (es) 2004-09-10

Family

ID=8179550

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04005767A MXPA04005767A (es) 2001-12-14 2002-12-12 Formacion previa para hacer tabletas de mezclas naturales de estrogenos conjugados.

Country Status (14)

Country Link
US (2) US8273728B2 (es)
EP (1) EP1458363B1 (es)
JP (1) JP4695838B2 (es)
CN (2) CN1298313C (es)
AR (1) AR037642A1 (es)
AU (1) AU2002358682B2 (es)
BR (1) BR0214954A (es)
CA (1) CA2470209A1 (es)
ES (1) ES2403218T3 (es)
HK (2) HK1075007A1 (es)
MX (1) MXPA04005767A (es)
PL (1) PL205544B1 (es)
TW (1) TWI332400B (es)
WO (1) WO2003051337A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9586335B2 (en) * 2010-01-27 2017-03-07 Sd3, Llc Blade guard with dust collection
TWI332400B (en) * 2001-12-14 2010-11-01 Solvay Pharm Gmbh Preformulation for the tableting of natural mixtures of conjugated estrogens
US8349819B2 (en) 2002-10-09 2013-01-08 Dr. Reddy's Laboratories New York, Inc. Steroid extraction process from urine sources
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US20090232897A1 (en) * 2008-03-14 2009-09-17 Bijayananda Sahoo Pharmaceutical compositions comprising conjugated estrogens
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
US20120100211A1 (en) * 2009-07-16 2012-04-26 James Farina Material and process for incorporation of low dosage active pharmaceutical ingredients and use thereof
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
WO2013083674A1 (de) * 2011-12-08 2013-06-13 Hexal Ag Neue pharmazeutische statin-zusammensetzung
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
EP3435977A4 (en) 2016-04-01 2019-10-16 Therapeuticsmd, Inc. PHARMACEUTICAL COMPOSITION OF STEROID HORMONE
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
WO2021162906A1 (en) * 2020-02-11 2021-08-19 Sheh Fung Screws Co., Ltd Fastener having improved wobble control, fastening system including the same, and method of forming the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487152A (en) * 1967-02-07 1969-12-30 Hoffmann La Roche Tablets containing 7 - chloro - 2 - methylamino - 5 - phenyl - 3h - 1,4 - benzodiazepine-4-oxide and conjugated estrogenic substances
US4154820A (en) * 1976-02-23 1979-05-15 Akzona Incorporated Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers
DE3535536A1 (de) * 1985-10-04 1987-04-09 Lentia Gmbh Verfahren zum gleichzeitigen trocknen und granulieren von extraktstoffen aus enteiweisstem kaelberblut
EP0322020A1 (en) * 1987-12-22 1989-06-28 Akzo N.V. Pharmaceutical dosage unit for treating climacteric complaints and osteoporosis
WO1997004752A1 (en) * 1995-07-26 1997-02-13 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions of conjugated estrogens and methods for their use
HU228763B1 (hu) 1996-08-30 2013-05-28 Abbott Products Gmbh Eljárás ösztrogének kinyerésére kancavizeletbõl
DE19681616B4 (de) 1996-08-30 2006-03-09 Solvay Pharmaceuticals Gmbh Prozeß zur Gewinnung von Oestrogenen aus Stutenharn
US6200289B1 (en) 1998-04-10 2001-03-13 Milestone Scientific, Inc. Pressure/force computer controlled drug delivery system and the like
JP2000156938A (ja) 1998-11-19 2000-06-06 Hokuto Denko Kk 電池の充放電試験装置
TWI332400B (en) * 2001-12-14 2010-11-01 Solvay Pharm Gmbh Preformulation for the tableting of natural mixtures of conjugated estrogens

Also Published As

Publication number Publication date
US8329679B2 (en) 2012-12-11
CN1298313C (zh) 2007-02-07
CN1607944A (zh) 2005-04-20
CN100502839C (zh) 2009-06-24
CN1977862A (zh) 2007-06-13
HK1104220A1 (en) 2008-01-11
CA2470209A1 (en) 2003-06-26
US20050009800A1 (en) 2005-01-13
US20120237666A1 (en) 2012-09-20
US8273728B2 (en) 2012-09-25
JP2005516923A (ja) 2005-06-09
AU2002358682B2 (en) 2009-03-26
AU2002358682A1 (en) 2003-06-30
AR037642A1 (es) 2004-11-17
ES2403218T3 (es) 2013-05-16
WO2003051337A1 (de) 2003-06-26
EP1458363B1 (de) 2013-01-16
JP4695838B2 (ja) 2011-06-08
PL368730A1 (en) 2005-04-04
TWI332400B (en) 2010-11-01
BR0214954A (pt) 2004-12-14
HK1075007A1 (en) 2005-12-02
EP1458363A1 (de) 2004-09-22
TW200408400A (en) 2004-06-01
PL205544B1 (pl) 2010-04-30

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