JP2002539161A5 - - Google Patents
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- Publication number
- JP2002539161A5 JP2002539161A5 JP2000604846A JP2000604846A JP2002539161A5 JP 2002539161 A5 JP2002539161 A5 JP 2002539161A5 JP 2000604846 A JP2000604846 A JP 2000604846A JP 2000604846 A JP2000604846 A JP 2000604846A JP 2002539161 A5 JP2002539161 A5 JP 2002539161A5
- Authority
- JP
- Japan
- Prior art keywords
- hutni
- peptide
- seq
- composition
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 description 60
- 239000000203 mixture Substances 0.000 description 40
- 239000008194 pharmaceutical composition Substances 0.000 description 28
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 26
- 125000003275 alpha amino acid group Chemical group 0.000 description 15
- 210000004027 cell Anatomy 0.000 description 15
- 210000001519 tissue Anatomy 0.000 description 13
- 239000002773 nucleotide Substances 0.000 description 12
- 125000003729 nucleotide group Chemical group 0.000 description 12
- 210000003205 muscle Anatomy 0.000 description 11
- 125000000539 amino acid group Chemical group 0.000 description 10
- 241000283690 Bos taurus Species 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 210000000845 cartilage Anatomy 0.000 description 5
- 239000003937 drug carrier Substances 0.000 description 5
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 description 4
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 4
- 230000033115 angiogenesis Effects 0.000 description 4
- 230000004663 cell proliferation Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000035475 disorder Diseases 0.000 description 4
- 210000002889 endothelial cell Anatomy 0.000 description 4
- 239000003112 inhibitor Substances 0.000 description 4
- 210000000981 epithelium Anatomy 0.000 description 3
- 210000005036 nerve Anatomy 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 210000001612 chondrocyte Anatomy 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 210000000663 muscle cell Anatomy 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26827499A | 1999-03-15 | 1999-03-15 | |
| US09/268,274 | 1999-03-15 | ||
| US09/442,099 US6465431B1 (en) | 1999-11-17 | 1999-11-17 | Pharmaceutical compositions comprising troponin subunits, fragments and homologs thereof and methods of their use to inhibit angiogenesis |
| US09/442,099 | 1999-11-17 | ||
| PCT/US2000/006667 WO2000054770A1 (en) | 1999-03-15 | 2000-03-14 | Pharmaceutical compositions comprising troponin subunits, fragments and homologs thereof and methods of their use to inhibit angiogenesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002539161A JP2002539161A (ja) | 2002-11-19 |
| JP2002539161A5 true JP2002539161A5 (enExample) | 2007-01-25 |
Family
ID=26952984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000604846A Pending JP2002539161A (ja) | 1999-03-15 | 2000-03-14 | トロポニンサブユニット、それらの断片および相同体を含む医薬組成物ならびに血管形成を抑制するためのそれらの使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1165059A4 (enExample) |
| JP (1) | JP2002539161A (enExample) |
| AU (1) | AU774596B2 (enExample) |
| CA (1) | CA2367611A1 (enExample) |
| WO (1) | WO2000054770A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7407767B2 (en) | 2003-04-16 | 2008-08-05 | Ono Pharmaceutical Co., Ltd. | Method of screening remedy for heart disease and medicinal composition for treating heart disease |
| JP2007526763A (ja) * | 2004-01-27 | 2007-09-20 | コンピュゲン エルティーディー． | 新規のヌクレオチドおよびアミノ酸配列、ならびにそれらを心臓疾患の診断に用いるアッセイおよび方法 |
| ES2644723T3 (es) * | 2008-07-23 | 2017-11-30 | F. Hoffmann-La Roche Ag | Identificación de sujetos susceptibles de tratamiento antiangiogénico |
| JP5553547B2 (ja) * | 2009-07-14 | 2014-07-16 | 俊一 梶岡 | トロポニン含有医薬組成物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5837680A (en) * | 1996-02-16 | 1998-11-17 | Children's Medical Center Corporation | Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis |
-
2000
- 2000-03-14 CA CA002367611A patent/CA2367611A1/en not_active Abandoned
- 2000-03-14 WO PCT/US2000/006667 patent/WO2000054770A1/en not_active Ceased
- 2000-03-14 AU AU37449/00A patent/AU774596B2/en not_active Ceased
- 2000-03-14 JP JP2000604846A patent/JP2002539161A/ja active Pending
- 2000-03-14 EP EP00916329A patent/EP1165059A4/en not_active Withdrawn
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