JP2002538827A - 細胞内リン酸化反応のレギュレータ - Google Patents

細胞内リン酸化反応のレギュレータ

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Publication number
JP2002538827A
JP2002538827A JP2000605750A JP2000605750A JP2002538827A JP 2002538827 A JP2002538827 A JP 2002538827A JP 2000605750 A JP2000605750 A JP 2000605750A JP 2000605750 A JP2000605750 A JP 2000605750A JP 2002538827 A JP2002538827 A JP 2002538827A
Authority
JP
Japan
Prior art keywords
hrip
polynucleotide
sequence
polypeptide
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000605750A
Other languages
English (en)
Japanese (ja)
Inventor
バンドマン、オルガ
タング、ワイ・トム
ユエ、ヘンリー
ヒルマン、ジェニファー・エル
ボーグン、マライア・アール
アジムザイ、ヤルダ
リュ、デュング・アイナ・エム
オウ−ヤング、ジャニス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Publication of JP2002538827A publication Critical patent/JP2002538827A/ja
Pending legal-status Critical Current

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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01037Protein kinase (2.7.1.37)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11013Protein kinase C (2.7.11.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03048Protein-tyrosine-phosphatase (3.1.3.48)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
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    • A61K38/00Medicinal preparations containing peptides
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid

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  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
JP2000605750A 1999-03-18 2000-03-17 細胞内リン酸化反応のレギュレータ Pending JP2002538827A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US12559399P 1999-03-18 1999-03-18
US13504999P 1999-05-20 1999-05-20
US14318899P 1999-07-09 1999-07-09
US60/143,188 1999-07-09
US60/135,049 1999-07-09
US60/125,593 1999-07-09
PCT/US2000/007277 WO2000055332A2 (fr) 1999-03-18 2000-03-17 Regulateur de la phosphorylation intracellulaire

Publications (1)

Publication Number Publication Date
JP2002538827A true JP2002538827A (ja) 2002-11-19

Family

ID=27383262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000605750A Pending JP2002538827A (ja) 1999-03-18 2000-03-17 細胞内リン酸化反応のレギュレータ

Country Status (5)

Country Link
EP (1) EP1192257A2 (fr)
JP (1) JP2002538827A (fr)
AU (1) AU3899600A (fr)
CA (1) CA2364739A1 (fr)
WO (1) WO2000055332A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2377135A1 (fr) 1999-04-23 2000-11-02 Ceptyr, Inc. Kinase phosphatase dsp-10 a double specificite activee par un mitogene
DE60027295T2 (de) * 1999-05-13 2007-01-18 Johnson & Johnson Pharmaceutical Research & Development, Llc Sphingosinekinase
JP2003501038A (ja) * 1999-05-28 2003-01-14 スージェン・インコーポレーテッド 蛋白質キナーゼ
WO2001012819A2 (fr) * 1999-08-13 2001-02-22 Sugen, Inc. Nouvelles phosphatases de proteines et diagnostic et traitement des troubles lies a la phosphatase
WO2001031029A2 (fr) * 1999-10-28 2001-05-03 Warner-Lambert Company Gene de la sphingosine kinase humaine
US6858427B2 (en) * 2000-02-14 2005-02-22 Genentech, Inc. Sphingosine kinases
IL151533A0 (en) 2000-02-29 2003-04-10 Mitsubishi Pharma Corp Novel cyclic amide derivatives
US20020102693A1 (en) * 2000-05-02 2002-08-01 Luche Ralf M. DSP-14 dual-specificity phosphatase
EP1227156A3 (fr) * 2001-01-30 2004-01-02 Aeomica, Inc. Protéine humaine contenant un domaine de protéine kinase
US20040096865A1 (en) * 2001-02-05 2004-05-20 Kohler Rainer H. Regulation of human tyrosine-specific protein phosphatase
EP1441034A4 (fr) * 2001-10-31 2006-06-07 Astellas Pharma Inc Methode d'evaluation d'inhibiteurs de la phosphatase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039446A2 (fr) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 proteines humaines secretees
US5955338A (en) * 1997-06-27 1999-09-21 Incyte Pharmaceuticals, Inc. Phosphatidylinositol 4,5-bisphosphate 5-phosphatase
US6235512B1 (en) * 1997-07-01 2001-05-22 Tularik Inc. IKK-α proteins, nucleic acids and methods

Also Published As

Publication number Publication date
EP1192257A2 (fr) 2002-04-03
WO2000055332A2 (fr) 2000-09-21
WO2000055332A3 (fr) 2002-01-10
AU3899600A (en) 2000-10-04
CA2364739A1 (fr) 2000-09-21

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