JP2002538106A - イソバレルアミド、イソ吉草酸、または関連化合物を用いてｃｎｓ活性の調節に影響を与えることによる、痙縮および痙攣を含む様々な病状の治療 - Google Patents
イソバレルアミド、イソ吉草酸、または関連化合物を用いてｃｎｓ活性の調節に影響を与えることによる、痙縮および痙攣を含む様々な病状の治療Info
- Publication number
- JP2002538106A JP2002538106A JP2000602054A JP2000602054A JP2002538106A JP 2002538106 A JP2002538106 A JP 2002538106A JP 2000602054 A JP2000602054 A JP 2000602054A JP 2000602054 A JP2000602054 A JP 2000602054A JP 2002538106 A JP2002538106 A JP 2002538106A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- isovaleramide
- condition
- isovaleric acid
- dimethylisovaleramide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
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- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
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- Medical Informatics (AREA)
- Botany (AREA)
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- Mycology (AREA)
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- Addiction (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/258,882 US6589994B1 (en) | 1996-08-30 | 1999-03-01 | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound |
| US09/258,882 | 1999-03-01 | ||
| PCT/US2000/005324 WO2000051586A2 (en) | 1999-03-01 | 2000-03-01 | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting modulation of cns activity with isovaleramide, isovaleric acid, or a related compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002538106A true JP2002538106A (ja) | 2002-11-12 |
| JP2002538106A5 JP2002538106A5 (https=) | 2007-04-26 |
Family
ID=22982536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000602054A Pending JP2002538106A (ja) | 1999-03-01 | 2000-03-01 | イソバレルアミド、イソ吉草酸、または関連化合物を用いてｃｎｓ活性の調節に影響を与えることによる、痙縮および痙攣を含む様々な病状の治療 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6589994B1 (https=) |
| EP (1) | EP1176953A2 (https=) |
| JP (1) | JP2002538106A (https=) |
| AU (1) | AU779418B2 (https=) |
| CA (1) | CA2366038A1 (https=) |
| WO (1) | WO2000051586A2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007530493A (ja) * | 2004-03-26 | 2007-11-01 | シュバルツ ファルマ アクチェンゲゼルシャフト | 痛みのある糖尿病性神経障害における疼痛を治療するためのペプチド化合物の新規使用 |
| KR20180054381A (ko) * | 2016-11-15 | 2018-05-24 | 경희대학교 산학협력단 | 쥐오줌풀 추출물을 유효성분으로 포함하는 측두엽 뇌전증 예방 또는 치료용 약학적 조성물 |
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| US6589994B1 (en) * | 1996-08-30 | 2003-07-08 | Nps Pharmaceuticals, Inc. | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound |
| US7235258B1 (en) * | 1999-10-19 | 2007-06-26 | Nps Pharmaceuticals, Inc. | Sustained-release formulations for treating CNS-mediated disorders |
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| US7205151B2 (en) * | 2001-06-20 | 2007-04-17 | Metaproteomics, Llc | Complex mixtures exhibiting selective inhibition of cyclooxygenase-2 |
| US20090263522A1 (en) * | 2001-10-26 | 2009-10-22 | Babish John G | Curcuminoid Compositions Exhibiting Synergistic Inhibition Of The Expression And/Or Activity Of Cyclooxygenase-2 |
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| US20030134844A1 (en) * | 2001-10-31 | 2003-07-17 | Pfizer Inc. | Nicontinic acetylcholine receptor antagonists in the treatment of restless legs syndrome |
| US8158160B2 (en) | 2001-11-13 | 2012-04-17 | Eric Hauser Kuhrts | Anti-inflammatory cyclooxygenase inhibitors |
| AU2003286549B2 (en) * | 2002-10-21 | 2006-11-30 | Metaproteomics, Llc | Compositions that treat or inhibit pathological conditions associated with inflammatory response |
| AU2004283065B2 (en) * | 2003-05-22 | 2009-11-26 | Metaproteomics, Llc | Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment or prevention of gastric toxicity |
| US20050112215A1 (en) * | 2003-10-09 | 2005-05-26 | Valerie Otto | Cramp bark extract and method of extraction |
| WO2005046659A2 (en) * | 2003-11-12 | 2005-05-26 | Nps Pharmaceuticals, Inc. | Migraine treatments including isovaleramide compounds and serotonin agonists |
| US7297522B2 (en) * | 2003-11-18 | 2007-11-20 | Ultra Biotech Limited | Methods and compositions for treating epilepsy |
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| US20050192356A1 (en) * | 2004-02-27 | 2005-09-01 | Babish John G. | Synergistic anti-inflammatory pharmaceutical compositions and methods of use |
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| WO2006012603A2 (en) * | 2004-07-22 | 2006-02-02 | Nps Pharmaceuticals, Inc. | Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases |
| PL1781276T3 (pl) | 2004-08-27 | 2010-11-30 | Ucb Pharma Gmbh | Zastosowanie związków peptydowych do leczenia bólu związanego z rakiem kości, bólu indukowanego przez chemioterapię oraz nukleozydy |
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| US20070087977A1 (en) * | 2004-11-16 | 2007-04-19 | Wendye Robbins | Methods and compositions for treating pain |
| CA2587406A1 (en) * | 2004-11-16 | 2006-05-26 | Limerick Neurosciences, Inc. | Methods and compositions for treating pain |
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| CA2618613A1 (en) * | 2005-08-09 | 2007-02-22 | Metaproteomics, Llc | Protein kinase modulation by hops and acacia products |
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| EP2152684A4 (en) * | 2007-05-11 | 2011-05-18 | Metaproteomics Llc | METHOD AND COMPOSITIONS FOR THE DETOXIFICATION OF HEAVY METAL |
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| KR20100131969A (ko) * | 2007-12-10 | 2010-12-16 | 메타프로테오믹스, 엘엘씨 | 암, 혈관신생 및 이와 관련된 염증 경로의 치환된 1,3-시클로펜타디온 다중-표적 단백질 키나아제 조절제 |
| RU2010142655A (ru) | 2008-03-19 | 2012-04-27 | Ауриммед Фарма, Инк. (Us) | Соединение, пригодное для лечения болезней и нарушений центральной нервной системы, и способ его получения |
| US9212155B2 (en) | 2008-03-19 | 2015-12-15 | Aurimmed Pharma, Inc. | Compounds advantageous in the treatment of central nervous system diseases and disorders |
| US10793515B2 (en) | 2008-03-19 | 2020-10-06 | Aurimmed Pharma, Inc. | Compounds advantageous in the treatment of central nervous system diseases and disorders |
| US20210130285A1 (en) | 2008-03-19 | 2021-05-06 | Aurimmed Pharma, Inc. | Novel compounds advantageous in the treatment of central nervous system diseases and disorders |
| JP2011516492A (ja) * | 2008-04-02 | 2011-05-26 | メタプロテオミクス， エルエルシー | 内皮炎症及び内皮−単球相互作用の置換１，３−シクロペンタジオンによる減弱 |
| US9808434B2 (en) | 2011-01-27 | 2017-11-07 | City Of Hope | Compound for treating cancer and diabetes |
| WO2012103523A2 (en) | 2011-01-27 | 2012-08-02 | Samuel Rahbar | Novel modulators of development of adipocyte and cancer cells |
| EP2675297A4 (en) * | 2011-02-16 | 2014-10-01 | Wellbemed Sweden Ab | FOOD WITH AN EXTRACT MIXTURE |
| ES3059582T3 (en) | 2016-02-29 | 2026-03-23 | Bio Pharm Solutions Co Ltd | Sulfamate derivative compounds, processes for preparing them and their uses |
| US11670410B1 (en) * | 2022-04-13 | 2023-06-06 | Green Sky Creations LLC | Systems and methods to automatically administer a psychoactive substance to an airway of a user based on a detected event or condition |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH09501908A (ja) * | 1993-06-11 | 1997-02-25 | エヌピーエス ファーマシューティカルズ，インク． | 穏和不安緩解薬および穏和鎮静薬としてのイソバレラマイドの使用 |
| WO1998008498A1 (en) * | 1996-08-30 | 1998-03-05 | Nps Pharmaceuticals, Inc. | Treatment of spasticity, convulsions by isovaleric acid derivatives cns depressants |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE1617555C3 (de) | 1966-04-19 | 1974-09-19 | Kali-Chemie Ag, 3000 Hannover | Verfahren zur Isolierung von therapeutisch wertvollen Isovaleriansäureestern aus Valeriana- und Kentranthus-Extrakten |
| US5994392A (en) * | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
| US6107499A (en) * | 1988-02-26 | 2000-08-22 | Neuromedica, Inc. | Dopamine analog amide |
| US4933324A (en) * | 1988-02-26 | 1990-06-12 | Shashoua Victor E | Fatty acid-neuroactive drug conjugate as a prodrug |
| US4939174A (en) * | 1988-02-26 | 1990-07-03 | Shashoua Victor E | Appetite suppression with dopamine-fatty acid conjugates |
| IT1283951B1 (it) | 1996-03-15 | 1998-05-07 | Mendes Srl | Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di |
| US6589994B1 (en) * | 1996-08-30 | 2003-07-08 | Nps Pharmaceuticals, Inc. | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound |
| ATE295160T1 (de) | 1998-03-04 | 2005-05-15 | Nps Pharma Inc | Zusammensetzungen enthaltend isovalerianamide zusammen mit ibuprofen |
| JP2003512311A (ja) | 1999-10-19 | 2003-04-02 | エヌピーエス ファーマシューティカルズ インコーポレーテッド | Ｃｎｓ介在性障害を治療するための持続放出製剤 |
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1999
- 1999-03-01 US US09/258,882 patent/US6589994B1/en not_active Expired - Fee Related
-
2000
- 2000-03-01 EP EP00910383A patent/EP1176953A2/en not_active Withdrawn
- 2000-03-01 AU AU32483/00A patent/AU779418B2/en not_active Ceased
- 2000-03-01 JP JP2000602054A patent/JP2002538106A/ja active Pending
- 2000-03-01 CA CA002366038A patent/CA2366038A1/en not_active Abandoned
- 2000-03-01 WO PCT/US2000/005324 patent/WO2000051586A2/en not_active Ceased
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2003
- 2003-07-08 US US10/614,344 patent/US7265155B2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09501908A (ja) * | 1993-06-11 | 1997-02-25 | エヌピーエス ファーマシューティカルズ，インク． | 穏和不安緩解薬および穏和鎮静薬としてのイソバレラマイドの使用 |
| WO1998008498A1 (en) * | 1996-08-30 | 1998-03-05 | Nps Pharmaceuticals, Inc. | Treatment of spasticity, convulsions by isovaleric acid derivatives cns depressants |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007530493A (ja) * | 2004-03-26 | 2007-11-01 | シュバルツ ファルマ アクチェンゲゼルシャフト | 痛みのある糖尿病性神経障害における疼痛を治療するためのペプチド化合物の新規使用 |
| KR20180054381A (ko) * | 2016-11-15 | 2018-05-24 | 경희대학교 산학협력단 | 쥐오줌풀 추출물을 유효성분으로 포함하는 측두엽 뇌전증 예방 또는 치료용 약학적 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20040072900A1 (en) | 2004-04-15 |
| WO2000051586A3 (en) | 2001-11-29 |
| US6589994B1 (en) | 2003-07-08 |
| CA2366038A1 (en) | 2000-09-08 |
| WO2000051586A2 (en) | 2000-09-08 |
| EP1176953A2 (en) | 2002-02-06 |
| US7265155B2 (en) | 2007-09-04 |
| AU3248300A (en) | 2000-09-21 |
| AU779418B2 (en) | 2005-01-20 |
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