JP2002527504A - システインプロテアーゼのＩＣＥ／ｃｅｄ−３系の置換アシルジペプチジル抑制剤 - Google Patents

システインプロテアーゼのＩＣＥ／ｃｅｄ−３系の置換アシルジペプチジル抑制剤

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JP2002527504A
JP2002527504A JP2000577149A JP2000577149A JP2002527504A JP 2002527504 A JP2002527504 A JP 2002527504A JP 2000577149 A JP2000577149 A JP 2000577149A JP 2000577149 A JP2000577149 A JP 2000577149A JP 2002527504 A JP2002527504 A JP 2002527504A
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phenyl
naphthyl
substituted
cycloalkyl
mmol
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JP2002527504A5 (https=
Inventor
エス． カラニュースキー，ドナルド
ジェイ． カリッシュ，ビンセント
ディー． ロビンソン，エドワード
アール． ウルマン，ブレット
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アイドゥン ファーマシューティカルズ， インコーポレイテッド
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Publication of JP2002527504A publication Critical patent/JP2002527504A/ja
Publication of JP2002527504A5 publication Critical patent/JP2002527504A5/ja
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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JP2007506803A (ja) * 2003-05-27 2007-03-22 バーテックス　ファーマシューティカルズ　インコーポレイテッド カスパーゼ阻害剤およびそれらの用途
JP4791365B2 (ja) * 2003-05-27 2011-10-12 バーテックス ファーマシューティカルズ インコーポレイテッド カスパーゼ阻害剤およびそれらの用途
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JP2008538205A (ja) * 2005-03-07 2008-10-16 ガンガ， ラジュ ゴカラジュ， ボスウェル酸及び選択的に濃縮したボスウェル酸の新規な塩、ならびにそのための方法
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