JP2002523112A - 毒物学的反応マーカー - Google Patents

毒物学的反応マーカー

Info

Publication number
JP2002523112A
JP2002523112A JP2000567743A JP2000567743A JP2002523112A JP 2002523112 A JP2002523112 A JP 2002523112A JP 2000567743 A JP2000567743 A JP 2000567743A JP 2000567743 A JP2000567743 A JP 2000567743A JP 2002523112 A JP2002523112 A JP 2002523112A
Authority
JP
Japan
Prior art keywords
nucleic acid
molecule
acid molecule
sample
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000567743A
Other languages
English (en)
Japanese (ja)
Inventor
カニンガム、メアリー・ジェーン
ゼイガー、ゲーリー・ビー
パンザー、スコット・アール
サイルハマー、ジェフリー・ジェイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/141,825 external-priority patent/US6403778B1/en
Priority claimed from US09/172,711 external-priority patent/US6160105A/en
Priority claimed from US09/172,108 external-priority patent/US6160104A/en
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Publication of JP2002523112A publication Critical patent/JP2002523112A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000567743A 1998-08-28 1999-08-27 毒物学的反応マーカー Pending JP2002523112A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US09/141,825 1998-08-28
US09/141,825 US6403778B1 (en) 1998-05-04 1998-08-28 Toxicological response markers
US09/172,711 US6160105A (en) 1998-10-13 1998-10-13 Monitoring toxicological responses
US09/172,711 1998-10-13
US09/172,108 1998-10-13
US09/172,108 US6160104A (en) 1998-10-13 1998-10-13 Markers for peroxisomal proliferators
PCT/US1999/019768 WO2000012760A2 (fr) 1998-08-28 1999-08-27 Marqueurs de reaction toxicologique

Publications (1)

Publication Number Publication Date
JP2002523112A true JP2002523112A (ja) 2002-07-30

Family

ID=27385714

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000567743A Pending JP2002523112A (ja) 1998-08-28 1999-08-27 毒物学的反応マーカー

Country Status (5)

Country Link
EP (1) EP1108067A2 (fr)
JP (1) JP2002523112A (fr)
AU (1) AU6022299A (fr)
CA (1) CA2340589A1 (fr)
WO (1) WO2000012760A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6881571B1 (en) 1998-03-11 2005-04-19 Exonhit Therapeutics S.A. Qualitative differential screening
FR2798392B1 (fr) * 1999-09-13 2005-07-15 Exonhit Therapeutics Sa Marqueurs genetiques de la toxicite, preparation et utilisations
WO2002008453A2 (fr) * 2000-07-21 2002-01-31 Phase-1 Molecular Toxicology Genes canins de toxicite
AU2001280889A1 (en) * 2000-07-31 2002-02-13 Gene Logic, Inc. Molecular toxicology modeling
US7590493B2 (en) 2000-07-31 2009-09-15 Ocimum Biosolutions, Inc. Methods for determining hepatotoxins
WO2002066682A2 (fr) * 2001-01-29 2002-08-29 Phase-1 Molecular Toxicology, Inc. Us0204917genes de rats en rapport avec la toxicologie, et leurs utilisations
WO2002095000A2 (fr) 2001-05-22 2002-11-28 Gene Logic, Inc. Modelisation en toxicologie moleculaire
US7447594B2 (en) 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
JPWO2003014394A1 (ja) * 2001-08-03 2004-11-25 旭メディカル株式会社 生体適合性評価法
US20050112573A1 (en) * 2001-08-24 2005-05-26 Hitoshi Iwahashi Method of detecting toxic substance
US7469185B2 (en) 2002-02-04 2008-12-23 Ocimum Biosolutions, Inc. Primary rat hepatocyte toxicity modeling
EP1344834A3 (fr) * 2002-03-14 2004-06-02 F. Hoffmann-La Roche Ag Méthodes pour la prédiction de la toxicité d'un composé
GB0215509D0 (en) * 2002-07-04 2002-08-14 Novartis Ag Marker genes
WO2004058957A2 (fr) * 2002-12-31 2004-07-15 Pharmacia & Upjohn Company Llc Sequences de cyp1a2 canin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6114114A (en) * 1992-07-17 2000-09-05 Incyte Pharmaceuticals, Inc. Comparative gene transcript analysis
WO1997013877A1 (fr) * 1995-10-12 1997-04-17 Lynx Therapeutics, Inc. Mesure de profils d'expression genique pour evaluer la toxicite

Also Published As

Publication number Publication date
AU6022299A (en) 2000-03-21
WO2000012760A3 (fr) 2000-08-03
CA2340589A1 (fr) 2000-03-09
WO2000012760A2 (fr) 2000-03-09
EP1108067A2 (fr) 2001-06-20

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