CA2340589A1 - Marqueurs de reaction toxicologique - Google Patents
Marqueurs de reaction toxicologique Download PDFInfo
- Publication number
- CA2340589A1 CA2340589A1 CA002340589A CA2340589A CA2340589A1 CA 2340589 A1 CA2340589 A1 CA 2340589A1 CA 002340589 A CA002340589 A CA 002340589A CA 2340589 A CA2340589 A CA 2340589A CA 2340589 A1 CA2340589 A1 CA 2340589A1
- Authority
- CA
- Canada
- Prior art keywords
- nucleic acid
- dna
- molecule
- molecules
- misc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
L'invention concerne une composition comprenant plusieurs molécules d'acides nucléiques. La composition peut être utilisée sous la forme d'éléments hybridables d'un jeu ordonné de microéchantillons. La présente invention concerne aussi des procédés pour cribler des composés et des agents thérapeutiques à la recherche de réactions métaboliques indiquant la présence d'un composé toxique.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/141,825 US6403778B1 (en) | 1998-05-04 | 1998-08-28 | Toxicological response markers |
US09/141,825 | 1998-08-28 | ||
US09/172,711 | 1998-10-13 | ||
US09/172,711 US6160105A (en) | 1998-10-13 | 1998-10-13 | Monitoring toxicological responses |
US09/172,108 US6160104A (en) | 1998-10-13 | 1998-10-13 | Markers for peroxisomal proliferators |
US09/172,108 | 1998-10-13 | ||
PCT/US1999/019768 WO2000012760A2 (fr) | 1998-08-28 | 1999-08-27 | Marqueurs de reaction toxicologique |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2340589A1 true CA2340589A1 (fr) | 2000-03-09 |
Family
ID=27385714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002340589A Abandoned CA2340589A1 (fr) | 1998-08-28 | 1999-08-27 | Marqueurs de reaction toxicologique |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1108067A2 (fr) |
JP (1) | JP2002523112A (fr) |
AU (1) | AU6022299A (fr) |
CA (1) | CA2340589A1 (fr) |
WO (1) | WO2000012760A2 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6881571B1 (en) | 1998-03-11 | 2005-04-19 | Exonhit Therapeutics S.A. | Qualitative differential screening |
FR2798392B1 (fr) * | 1999-09-13 | 2005-07-15 | Exonhit Therapeutics Sa | Marqueurs genetiques de la toxicite, preparation et utilisations |
WO2002008453A2 (fr) * | 2000-07-21 | 2002-01-31 | Phase-1 Molecular Toxicology | Genes canins de toxicite |
US7590493B2 (en) | 2000-07-31 | 2009-09-15 | Ocimum Biosolutions, Inc. | Methods for determining hepatotoxins |
WO2002010453A2 (fr) * | 2000-07-31 | 2002-02-07 | Gene Logic, Inc. | Modelisation en toxicologie moleculaire |
EP1368499A2 (fr) * | 2001-01-29 | 2003-12-10 | Phase-1 Molecular Toxicology Inc. | Genes de rats en rapport avec la toxicologie, et leurs utilisations |
EP1392871A4 (fr) | 2001-05-22 | 2006-04-19 | Gene Logic Inc | Modelisation en toxicologie moleculaire |
US7447594B2 (en) | 2001-07-10 | 2008-11-04 | Ocimum Biosolutions, Inc. | Molecular cardiotoxicology modeling |
US20040241690A1 (en) * | 2001-08-03 | 2004-12-02 | Takayuki Souka | Method of evaluating biocompatibility |
WO2003018792A1 (fr) * | 2001-08-24 | 2003-03-06 | National Institute Of Advanced Industrial Science And Technology | Procede de detection d'une substance toxique |
US7469185B2 (en) | 2002-02-04 | 2008-12-23 | Ocimum Biosolutions, Inc. | Primary rat hepatocyte toxicity modeling |
EP1344834A3 (fr) * | 2002-03-14 | 2004-06-02 | F. Hoffmann-La Roche Ag | Méthodes pour la prédiction de la toxicité d'un composé |
GB0215509D0 (en) * | 2002-07-04 | 2002-08-14 | Novartis Ag | Marker genes |
JP2006512075A (ja) * | 2002-12-31 | 2006-04-13 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | イヌcyp1a2配列 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6114114A (en) * | 1992-07-17 | 2000-09-05 | Incyte Pharmaceuticals, Inc. | Comparative gene transcript analysis |
WO1997013877A1 (fr) * | 1995-10-12 | 1997-04-17 | Lynx Therapeutics, Inc. | Mesure de profils d'expression genique pour evaluer la toxicite |
-
1999
- 1999-08-27 AU AU60222/99A patent/AU6022299A/en not_active Abandoned
- 1999-08-27 EP EP99968250A patent/EP1108067A2/fr not_active Withdrawn
- 1999-08-27 CA CA002340589A patent/CA2340589A1/fr not_active Abandoned
- 1999-08-27 WO PCT/US1999/019768 patent/WO2000012760A2/fr not_active Application Discontinuation
- 1999-08-27 JP JP2000567743A patent/JP2002523112A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2000012760A3 (fr) | 2000-08-03 |
EP1108067A2 (fr) | 2001-06-20 |
WO2000012760A2 (fr) | 2000-03-09 |
JP2002523112A (ja) | 2002-07-30 |
AU6022299A (en) | 2000-03-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6372431B1 (en) | Mammalian toxicological response markers | |
US6160105A (en) | Monitoring toxicological responses | |
US6709855B1 (en) | Methods for detection and use of differentially expressed genes in disease states | |
EP0991770B1 (fr) | Gene associe au cancer de la prostate | |
Barker et al. | A mutation causing Alport syndrome with tardive hearing loss is common in the western United States. | |
US20020165345A1 (en) | Prostate cancer gene | |
US5945522A (en) | Prostate cancer gene | |
EP1140137A2 (fr) | Methodes de detection et d'utilisation de genes exprimes de fa on differentielle dans des maladies | |
NZ336483A (en) | Large scale genotyping of diseases and a diagnostic test for spinocerebellar ataxia type 6 | |
CA2340589A1 (fr) | Marqueurs de reaction toxicologique | |
US6025194A (en) | Nucleic acid sequence of senescence asssociated gene | |
US20030065157A1 (en) | Genes expressed in lung cancer | |
US20030175795A1 (en) | Polynucleotides associated with cardiac muscle function | |
US6403778B1 (en) | Toxicological response markers | |
US20030013099A1 (en) | Genes regulated by DNA methylation in colon tumors | |
JP2004507206A (ja) | 診断上重要な組織特異的遺伝子 | |
JP2002519027A (ja) | 網膜芽腫結合タンパク質(rbp−7)をコードする核酸および前記核酸に関連する多型マーカー | |
US6368794B1 (en) | Detection of altered expression of genes regulating cell proliferation | |
US20050130171A1 (en) | Genes expressed in Alzheimer's disease | |
US6448041B1 (en) | Colon cancer marker | |
Kidd et al. | Regulated expression of a cell division control-related protein kinase during development | |
US6160104A (en) | Markers for peroxisomal proliferators | |
JP5301281B2 (ja) | 臓器特異的遺伝子、その同定方法およびその用途 | |
US7189833B2 (en) | Prostate cancer gene | |
US20030096234A1 (en) | Canine toxicity genes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |