WO2000012760A3 - Marqueurs de reaction toxicologique - Google Patents
Marqueurs de reaction toxicologique Download PDFInfo
- Publication number
- WO2000012760A3 WO2000012760A3 PCT/US1999/019768 US9919768W WO0012760A3 WO 2000012760 A3 WO2000012760 A3 WO 2000012760A3 US 9919768 W US9919768 W US 9919768W WO 0012760 A3 WO0012760 A3 WO 0012760A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- response markers
- toxicological response
- composition
- relates
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU60222/99A AU6022299A (en) | 1998-08-28 | 1999-08-27 | Toxicological response markers |
CA002340589A CA2340589A1 (fr) | 1998-08-28 | 1999-08-27 | Marqueurs de reaction toxicologique |
JP2000567743A JP2002523112A (ja) | 1998-08-28 | 1999-08-27 | 毒物学的反応マーカー |
EP99968250A EP1108067A2 (fr) | 1998-08-28 | 1999-08-27 | Marqueurs de reaction toxicologique |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/141,825 US6403778B1 (en) | 1998-05-04 | 1998-08-28 | Toxicological response markers |
US09/172,108 US6160104A (en) | 1998-10-13 | 1998-10-13 | Markers for peroxisomal proliferators |
US09/172,711 US6160105A (en) | 1998-10-13 | 1998-10-13 | Monitoring toxicological responses |
US09/172,108 | 1998-10-13 | ||
US09/141,825 | 1998-10-13 | ||
US09/172,711 | 1998-10-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000012760A2 WO2000012760A2 (fr) | 2000-03-09 |
WO2000012760A3 true WO2000012760A3 (fr) | 2000-08-03 |
Family
ID=27385714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/019768 WO2000012760A2 (fr) | 1998-08-28 | 1999-08-27 | Marqueurs de reaction toxicologique |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1108067A2 (fr) |
JP (1) | JP2002523112A (fr) |
AU (1) | AU6022299A (fr) |
CA (1) | CA2340589A1 (fr) |
WO (1) | WO2000012760A2 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6881571B1 (en) | 1998-03-11 | 2005-04-19 | Exonhit Therapeutics S.A. | Qualitative differential screening |
FR2798392B1 (fr) * | 1999-09-13 | 2005-07-15 | Exonhit Therapeutics Sa | Marqueurs genetiques de la toxicite, preparation et utilisations |
AU2001280746A1 (en) | 2000-07-21 | 2002-02-05 | Phase-1 Molecular Toxicology | Canine toxicity genes |
AU2001280889A1 (en) * | 2000-07-31 | 2002-02-13 | Gene Logic, Inc. | Molecular toxicology modeling |
US7590493B2 (en) | 2000-07-31 | 2009-09-15 | Ocimum Biosolutions, Inc. | Methods for determining hepatotoxins |
JP2004535776A (ja) * | 2001-01-29 | 2004-12-02 | フェイズ − 1 モレキュラー トクシコロジー、インコーポレイテッド | ラット毒性関連遺伝子及びその使用 |
WO2002095000A2 (fr) | 2001-05-22 | 2002-11-28 | Gene Logic, Inc. | Modelisation en toxicologie moleculaire |
US7447594B2 (en) | 2001-07-10 | 2008-11-04 | Ocimum Biosolutions, Inc. | Molecular cardiotoxicology modeling |
EP1413629A1 (fr) * | 2001-08-03 | 2004-04-28 | ASAHI MEDICAL Co., Ltd. | Methode d'evaluation de la biocompatibilite |
DE60236559D1 (de) * | 2001-08-24 | 2010-07-08 | Daikin Ind Ltd | Verfahren zum Nachweis toxischer Substanzen |
US7469185B2 (en) | 2002-02-04 | 2008-12-23 | Ocimum Biosolutions, Inc. | Primary rat hepatocyte toxicity modeling |
EP1344834A3 (fr) * | 2002-03-14 | 2004-06-02 | F. Hoffmann-La Roche Ag | Méthodes pour la prédiction de la toxicité d'un composé |
GB0215509D0 (en) * | 2002-07-04 | 2002-08-14 | Novartis Ag | Marker genes |
AU2003288649A1 (en) * | 2002-12-31 | 2004-07-22 | Pharmacia & Upjohn Company Llc | Canine cyp1a2 sequences |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995020681A1 (fr) * | 1994-01-27 | 1995-08-03 | Incyte Pharmaceuticals, Inc. | Analyse comparative de produits de transcription geniques |
WO1997013877A1 (fr) * | 1995-10-12 | 1997-04-17 | Lynx Therapeutics, Inc. | Mesure de profils d'expression genique pour evaluer la toxicite |
-
1999
- 1999-08-27 EP EP99968250A patent/EP1108067A2/fr not_active Withdrawn
- 1999-08-27 AU AU60222/99A patent/AU6022299A/en not_active Abandoned
- 1999-08-27 WO PCT/US1999/019768 patent/WO2000012760A2/fr not_active Application Discontinuation
- 1999-08-27 JP JP2000567743A patent/JP2002523112A/ja active Pending
- 1999-08-27 CA CA002340589A patent/CA2340589A1/fr not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995020681A1 (fr) * | 1994-01-27 | 1995-08-03 | Incyte Pharmaceuticals, Inc. | Analyse comparative de produits de transcription geniques |
WO1997013877A1 (fr) * | 1995-10-12 | 1997-04-17 | Lynx Therapeutics, Inc. | Mesure de profils d'expression genique pour evaluer la toxicite |
Non-Patent Citations (3)
Title |
---|
DATABASE EMBL embl heidelberg; 30 September 1995 (1995-09-30), LEE H.N. ET AL.,: "EST108960 rat PC-12 cells", XP002130308 * |
LEE N.H. ET AL.,: "Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment", PROC. NATL. ACAD. SCI. USA, vol. 92, - August 1995 (1995-08-01), pages 8303 - 8307, XP002047703 * |
SCHENA M ET AL: "PARALLEL HUMAN GENOME ANALYSIS: MICROARRAY-BASED EXPRESSION MONITORING OF 1000 GENES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA,US,NATIONAL ACADEMY OF SCIENCE. WASHINGTON, vol. 93, no. 20, 1 October 1996 (1996-10-01), pages 10614 - 10619, XP002912238, ISSN: 0027-8424 * |
Also Published As
Publication number | Publication date |
---|---|
AU6022299A (en) | 2000-03-21 |
WO2000012760A2 (fr) | 2000-03-09 |
EP1108067A2 (fr) | 2001-06-20 |
CA2340589A1 (fr) | 2000-03-09 |
JP2002523112A (ja) | 2002-07-30 |
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