AU2001285219A1 - Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization - Google Patents

Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization

Info

Publication number
AU2001285219A1
AU2001285219A1 AU2001285219A AU8521901A AU2001285219A1 AU 2001285219 A1 AU2001285219 A1 AU 2001285219A1 AU 2001285219 A AU2001285219 A AU 2001285219A AU 8521901 A AU8521901 A AU 8521901A AU 2001285219 A1 AU2001285219 A1 AU 2001285219A1
Authority
AU
Australia
Prior art keywords
hybridization
compositions
methods
nucleic acid
acid molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001285219A
Inventor
Jing Cheng
Guoqing Wang
Xiao-Bo Wang
Lei Wu
Weiping Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aviva Biosciences Corp
Original Assignee
Aviva Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN 00123633 external-priority patent/CN1277933C/en
Priority claimed from US09/648,081 external-priority patent/US6900013B1/en
Application filed by Aviva Biosciences Corp filed Critical Aviva Biosciences Corp
Publication of AU2001285219A1 publication Critical patent/AU2001285219A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
AU2001285219A 2000-08-24 2001-08-22 Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization Abandoned AU2001285219A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN00123633 2000-08-24
CN 00123633 CN1277933C (en) 2000-08-24 2000-08-24 Method and composite for identifying nucleic acid molecule by nucleic acid enzymolysis activity and hybrid technology
US09648081 2000-08-24
US09/648,081 US6900013B1 (en) 2000-08-25 2000-08-25 Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization
PCT/US2001/026291 WO2002016647A1 (en) 2000-08-24 2001-08-22 Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization

Publications (1)

Publication Number Publication Date
AU2001285219A1 true AU2001285219A1 (en) 2002-03-04

Family

ID=25739542

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001285219A Abandoned AU2001285219A1 (en) 2000-08-24 2001-08-22 Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization

Country Status (4)

Country Link
US (1) US20030138838A1 (en)
EP (1) EP1387894A4 (en)
AU (1) AU2001285219A1 (en)
WO (1) WO2002016647A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100494360C (en) 2001-03-22 2009-06-03 博奥生物有限公司 Process for separating cells and its application
US20060029955A1 (en) 2001-03-24 2006-02-09 Antonio Guia High-density ion transport measurement biochip devices and methods
CA2441366A1 (en) 2001-03-24 2002-10-03 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
KR100436554B1 (en) * 2001-04-17 2004-06-18 삼성전자주식회사 A Method for Improving a Sensitivity of Sensing Device in the Detection of a Hybridized Nucleic Acid
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
WO2003093494A2 (en) 2002-05-04 2003-11-13 Aviva Biosciences Corporation Apparatus including ion transport detecting structures and methods of use
US7718365B2 (en) * 2005-07-09 2010-05-18 Agilent Technologies, Inc. Microarray analysis of RNA
US8076064B2 (en) 2005-07-09 2011-12-13 Agilent Technologies, Inc. Method of treatment of RNA sample
DE102005039726B3 (en) 2005-08-19 2007-01-11 Universität Rostock Detecting nucleic acid sequence, comprises hybridizing single stranded target strand with protected strand, reacting part of strand with redoxmarker, hybridizing surface with immobilized probe and hybridizing by electro analytical process
US20070281309A1 (en) * 2006-05-19 2007-12-06 Massachusetts Institute Of Technology Microfluidic-based Gene Synthesis
CA2657621A1 (en) 2006-07-14 2008-01-17 Aviva Biosciences Corporation Methods and compositions for detecting rare cells from a biological sample
JP2010520747A (en) 2007-02-23 2010-06-17 パナジェン インコーポレイテッド Method, composition, and kit for increasing the hybridization efficiency or specificity of PNA probe and target nucleic acid immobilized on a support
US9765385B2 (en) 2012-06-29 2017-09-19 Htg Molecular Diagnostics, Inc. Nuclease protection methods for detection of nucleotide variants
US9804069B2 (en) * 2012-12-19 2017-10-31 Dnae Group Holdings Limited Methods for degrading nucleic acid
US9315807B1 (en) 2013-01-26 2016-04-19 New England Biolabs, Inc. Genome selection and conversion method
US10087481B2 (en) 2013-03-19 2018-10-02 New England Biolabs, Inc. Enrichment of target sequences
EP3312295A1 (en) * 2013-03-19 2018-04-25 Directed Genomics, LLC Enrichment of target sequences
WO2020086896A1 (en) * 2018-10-24 2020-04-30 University Of Washington Methods and kits for depletion and enrichment of nucleic acid sequences
CN113166797B (en) * 2018-12-21 2024-04-12 Illumina公司 Nuclease-based RNA depletion

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL202210A (en) * 1954-11-22
US3687808A (en) * 1969-08-14 1972-08-29 Univ Leland Stanford Junior Synthetic polynucleotides
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
GB8822228D0 (en) * 1988-09-21 1988-10-26 Southern E M Support-bound oligonucleotides
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6040138A (en) * 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5527681A (en) * 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US5242974A (en) * 1991-11-22 1993-09-07 Affymax Technologies N.V. Polymer reversal on solid surfaces
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
DE3924454A1 (en) * 1989-07-24 1991-02-07 Cornelis P Prof Dr Hollenberg THE APPLICATION OF DNA AND DNA TECHNOLOGY FOR THE CONSTRUCTION OF NETWORKS FOR USE IN CHIP CONSTRUCTION AND CHIP PRODUCTION (DNA CHIPS)
US5646019A (en) * 1989-10-24 1997-07-08 Stratagene Method for producing primed nucleic acid templates
US5573907A (en) * 1990-01-26 1996-11-12 Abbott Laboratories Detecting and amplifying target nucleic acids using exonucleolytic activity
US6013431A (en) * 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
US5888819A (en) * 1991-03-05 1999-03-30 Molecular Tool, Inc. Method for determining nucleotide identity through primer extension
IL103674A0 (en) * 1991-11-19 1993-04-04 Houston Advanced Res Center Method and apparatus for molecule detection
US5412087A (en) * 1992-04-24 1995-05-02 Affymax Technologies N.V. Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
US5384261A (en) * 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
US5359115A (en) * 1992-03-26 1994-10-25 Affymax Technologies, N.V. Methods for the synthesis of phosphonate esters
US5420328A (en) * 1992-09-11 1995-05-30 Affymax Technologies, N.V. Methods for the synthesis of phosphonate esters
EP0625213B1 (en) * 1992-10-09 1999-12-29 VYSIS, Inc. Assay methods
US5554501A (en) * 1992-10-29 1996-09-10 Beckman Instruments, Inc. Biopolymer synthesis using surface activated biaxially oriented polypropylene
US5681943A (en) * 1993-04-12 1997-10-28 Northwestern University Method for covalently linking adjacent oligonucleotides
US5472672A (en) * 1993-10-22 1995-12-05 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and method for polymer synthesis using arrays
US5429807A (en) * 1993-10-28 1995-07-04 Beckman Instruments, Inc. Method and apparatus for creating biopolymer arrays on a solid support surface
ATE247716T1 (en) * 1994-02-07 2003-09-15 Beckman Coulter Inc LIGASE/POLYMERASE-MEDIATED ANALYSIS OF GENETIC ELEMENTS OF SINGLE NUCLEOTIDE POLYMORPHISMS AND THEIR USE IN GENETIC ANALYSIS
US5571639A (en) * 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US5556752A (en) * 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US5599695A (en) * 1995-02-27 1997-02-04 Affymetrix, Inc. Printing molecular library arrays using deprotection agents solely in the vapor phase
US5624711A (en) * 1995-04-27 1997-04-29 Affymax Technologies, N.V. Derivatization of solid supports and methods for oligomer synthesis
US5753439A (en) * 1995-05-19 1998-05-19 Trustees Of Boston University Nucleic acid detection methods
US5545531A (en) * 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
FR2737502B1 (en) * 1995-07-31 1997-10-24 Genset Sa NUCLEIC ACID DETECTION METHOD USING NUCLEOTIDE PROBES ALLOWING BOTH SPECIFIC CAPTURE AND DETECTION
US5658734A (en) * 1995-10-17 1997-08-19 International Business Machines Corporation Process for synthesizing chemical compounds
DE19548680A1 (en) * 1995-12-23 1997-06-26 Boehringer Mannheim Gmbh Method for the quantitative detection of specific nucleic acid sequences
US5770370A (en) * 1996-06-14 1998-06-23 David Sarnoff Research Center, Inc. Nuclease protection assays
US5998136A (en) * 1996-08-19 1999-12-07 Arcaris, Inc. Selection systems and methods for identifying genes and gene products involved in cell proliferation
GB2324370B (en) * 1997-04-14 1999-03-03 Stuart Harbron Detection of hybrid double-stranded DNA with antibody after enzyme degradation of excess single-standed DNA
US6004752A (en) * 1997-07-29 1999-12-21 Sarnoff Corporation Solid support with attached molecules
US6238869B1 (en) * 1997-12-19 2001-05-29 High Throughput Genomics, Inc. High throughput assay system
US6232066B1 (en) * 1997-12-19 2001-05-15 Neogen, Inc. High throughput assay system
US6458533B1 (en) * 1997-12-19 2002-10-01 High Throughput Genomics, Inc. High throughput assay system for monitoring ESTs
US5994079A (en) * 1998-02-06 1999-11-30 Digene Corporation Direct detection of RNA mediated by reverse transcriptase lacking RNAse H function
US6004755A (en) * 1998-04-07 1999-12-21 Incyte Pharmaceuticals, Inc. Quantitative microarray hybridizaton assays
JPH11348343A (en) * 1998-06-03 1999-12-21 Canon Inc Method and apparatus for forming image
US6441152B1 (en) * 1998-12-08 2002-08-27 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
AU2375600A (en) * 1998-12-22 2000-07-12 Stephen Felder High throughput assay system using mass spectrometry
US6448010B1 (en) * 1999-10-06 2002-09-10 Amersham Pharmacia Biotech, Inc. Method for detecting mutations using arrayed primer extension

Also Published As

Publication number Publication date
WO2002016647A1 (en) 2002-02-28
EP1387894A1 (en) 2004-02-11
US20030138838A1 (en) 2003-07-24
EP1387894A4 (en) 2006-10-11

Similar Documents

Publication Publication Date Title
AU2001285219A1 (en) Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization
AU2001255518A1 (en) Compositions and methods for array-based nucleic acid hybridization
AU3459301A (en) Compositions and methods for performing biological reactions
AU2001268513A1 (en) Nucleic acid accessible hybridization sites
AU2001273453A1 (en) Nucleic acid hairpin probes and uses thereof
AU2002239284A1 (en) Methods and devices for characterizing duplex nucleic acid molecules
AU3719700A (en) Enzymatic dna molecules that contain modified nucleotides
AU3199699A (en) Modified nucleotides and methods useful for nucleic acid sequencing
AU2001280968A1 (en) Compositions and methods for directed gene assembly
AU8909998A (en) Methods and compositions for cloning nucleic acid molecules
AU2003239129A1 (en) Methods and compositions for dna manipulation
AU2002365811A1 (en) Methods for the selection and cloning of nucleic acid molecules free of unwanted nucleotide sequence alterations
AU3347500A (en) Methods and kits for characterizing gc-rich nucleic acid sequences
AU2001245987A1 (en) Compositions and methods for gene therapy
AU2003303588A1 (en) Methods and compositions for sequencing nucleic acid molecules
AU7265298A (en) Methods and compositions for targeted dna differential display
AU2002211498A1 (en) Efficient tests of association for quantitative traits and affected-unaffected studies using pooled dna
AU2003220608A1 (en) Oligoribonucleotides and ribonucleases for cleaving rna
AU1908100A (en) Isothermal nucleic acid amplification methods
AU2002311759A1 (en) Methods and compositions for analyzing nucleic acids
AU6094200A (en) Nor gene compositions and methods for use thereof
IL157703A0 (en) Methods for delivering nucleic acid molecules into cells and assessment thereof
AU2001260313A1 (en) Compositions and methods for nucleic acid analyses
AU5474400A (en) Compositions and methods for targeted gene insertion
AU2002213695A1 (en) Method of genomic analysis