JP2002521065A5 - - Google Patents

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Publication number
JP2002521065A5
JP2002521065A5 JP2000562554A JP2000562554A JP2002521065A5 JP 2002521065 A5 JP2002521065 A5 JP 2002521065A5 JP 2000562554 A JP2000562554 A JP 2000562554A JP 2000562554 A JP2000562554 A JP 2000562554A JP 2002521065 A5 JP2002521065 A5 JP 2002521065A5
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JP
Japan
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seq
nos
amino acid
acid residue
mutation
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JP2000562554A
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English (en)
Japanese (ja)
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JP2002521065A (ja
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Priority claimed from US09/226,012 external-priority patent/US6207383B1/en
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Publication of JP2002521065A publication Critical patent/JP2002521065A/ja
Publication of JP2002521065A5 publication Critical patent/JP2002521065A5/ja
Withdrawn legal-status Critical Current

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JP2000562554A 1998-07-27 1999-07-20 Ｈｅｒｇ−長期ｑｔ症候群遺伝子中の突然変異およびそのゲノム構造 Withdrawn JP2002521065A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12284798A 1998-07-27 1998-07-27
US09/122,847 1998-07-27
US09/226,012 US6207383B1 (en) 1998-07-27 1999-01-06 Mutations in and genomic structure of HERG—a long QT syndrome gene
US09/226,012 1999-01-06
PCT/US1999/016337 WO2000006772A1 (en) 1998-07-27 1999-07-20 Mutations in and genomic structure of herg - a long qt syndrome gene

Publications (2)

Publication Number Publication Date
JP2002521065A JP2002521065A (ja) 2002-07-16
JP2002521065A5 true JP2002521065A5 (https=) 2006-09-14

Family

ID=26820952

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000562554A Withdrawn JP2002521065A (ja) 1998-07-27 1999-07-20 Ｈｅｒｇ−長期ｑｔ症候群遺伝子中の突然変異およびそのゲノム構造

Country Status (6)

Country Link
US (3) US6207383B1 (https=)
EP (2) EP1553190A3 (https=)
JP (1) JP2002521065A (https=)
AU (2) AU774194B2 (https=)
CA (1) CA2336236C (https=)
WO (1) WO2000006772A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274332B1 (en) * 1995-12-22 2001-08-14 Univ. Of Utah Research Foundation Mutations in the KCNE1 gene encoding human minK which cause arrhythmia susceptibility thereby establishing KCNE1 as an LQT gene
US6207383B1 (en) * 1998-07-27 2001-03-27 University Of Utah Research Foundation Mutations in and genomic structure of HERG—a long QT syndrome gene
US6852704B1 (en) * 1999-01-19 2005-02-08 The Children's Hospital Of Philadelphia Reverse gene therapy
US7282489B2 (en) * 2000-01-19 2007-10-16 The Children's Hospital Of Philadelphia Compositions and methods for performing reverse gene therapy
ATE381626T1 (de) * 2000-04-13 2008-01-15 Univ Georgetown Genetische diagnose zur feststellung von qt- verlängerungen als unerwünschte reaktion auf arzneimittel
DE10224534A1 (de) * 2002-05-31 2003-12-11 Juergen Dolderer Verfahren zum Diagnostizieren des colorektaien Karzinoms in einer Gewebeprobe und Mittel zur Behandlung
KR20040023166A (ko) * 2002-09-11 2004-03-18 학교법인 계명기독학원 유전자 돌연변이 및 ｓｎｐ 탐지용 프라이머를 이용한ｑｔ연장증후군의 진단방법
US7537928B2 (en) * 2003-08-22 2009-05-26 Masonic Medical Research Laboratory Mutations in ion channel proteins associated with sudden cardiac death
CA2537746A1 (en) 2003-09-04 2005-03-17 Poseidon Pharmaceuticals A/S Erg channel openers for the treatment of cardiac arrhythmias
US20050064547A1 (en) * 2003-09-24 2005-03-24 Brown Arthur M. Vectors and transfected cells
WO2005042732A2 (en) * 2003-10-28 2005-05-12 Wisconsin Alumni Research Foundation STABLE CELL LINES EXPRESSING HERG1a AND HERG1b
US20070239230A1 (en) * 2004-12-17 2007-10-11 Medtronic, Inc. System and method for regulating cardiac triggered therapy to the brain
US7833718B2 (en) * 2006-11-06 2010-11-16 Masonic Medical Research Laboratory CACNA1C nucleic acid mutations as indicators of shorter than normal QT interval and ST segment elevation associated with sudden cardiac death
US20090047703A1 (en) * 2007-08-17 2009-02-19 University Of Maryland, Baltimore ERG-1 Peptides and Polynucleotides and Their Use in the Treatment and Diagnosis of Disease
US20110151484A1 (en) * 2008-05-20 2011-06-23 Victor Chang Cardiac Research Institute Limited hERG MUTANTS AND USES THEREOF
US11579152B2 (en) * 2016-04-01 2023-02-14 The Rockefeller University Engineered hERG channel proteins, vesicles and methods of identifying small molecule pharmacological agents
CA3036726A1 (en) 2016-09-15 2018-03-22 The Governors Of The University Of Alberta Recombinant cardiomyocytes and cardiomyocyte cell lines expressing herg
BR112020002871A2 (pt) * 2017-08-15 2020-07-28 Kindred Biosciences, Inc. variantes fc de igg para uso veterinário
CN117487907B (zh) * 2023-12-29 2024-04-23 湖南家辉生物技术有限公司 Kcnh2基因突变体、突变体蛋白、试剂、试剂盒及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599673A (en) 1995-03-09 1997-02-04 University Of Utah Research Foundation Long QT syndrome genes
US6207383B1 (en) * 1998-07-27 2001-03-27 University Of Utah Research Foundation Mutations in and genomic structure of HERG—a long QT syndrome gene

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