JP2002517521A - アシル化アルキル化シクロデキストリン誘導体及びその薬物担体としての使用 - Google Patents

アシル化アルキル化シクロデキストリン誘導体及びその薬物担体としての使用

Info

Publication number
JP2002517521A
JP2002517521A JP2000552168A JP2000552168A JP2002517521A JP 2002517521 A JP2002517521 A JP 2002517521A JP 2000552168 A JP2000552168 A JP 2000552168A JP 2000552168 A JP2000552168 A JP 2000552168A JP 2002517521 A JP2002517521 A JP 2002517521A
Authority
JP
Japan
Prior art keywords
cyd
group
derivatives
mixture
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000552168A
Other languages
English (en)
Japanese (ja)
Inventor
兼人 上釜
文俊 平山
明 近藤
博志 川路
正昭 太田
安弘 岡本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of JP2002517521A publication Critical patent/JP2002517521A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
JP2000552168A 1998-05-29 1999-05-27 アシル化アルキル化シクロデキストリン誘導体及びその薬物担体としての使用 Withdrawn JP2002517521A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10-164465 1998-05-29
JP16446598 1998-05-29
PCT/JP1999/002806 WO1999062958A1 (fr) 1998-05-29 1999-05-27 Derives de cyclodextrine alkyle acyle et leur utilisation en tant qu'excipients pour medicaments

Publications (1)

Publication Number Publication Date
JP2002517521A true JP2002517521A (ja) 2002-06-18

Family

ID=15793704

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000552168A Withdrawn JP2002517521A (ja) 1998-05-29 1999-05-27 アシル化アルキル化シクロデキストリン誘導体及びその薬物担体としての使用

Country Status (4)

Country Link
EP (1) EP1084149A1 (fr)
JP (1) JP2002517521A (fr)
AU (1) AU3954799A (fr)
WO (1) WO1999062958A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006521403A (ja) * 2003-03-28 2006-09-21 アイバックス コーポレイション クラドリビンの経口製剤

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6835717B2 (en) 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
JP2003063965A (ja) * 2001-06-13 2003-03-05 Otsuka Pharmaceut Factory Inc 注射用シロスタゾール水性製剤
US20050171057A1 (en) * 2002-01-15 2005-08-04 Altana Pharma Ag Pantoprazole cyclodextrin inclusion complexes
FR2903987B1 (fr) * 2006-07-21 2012-12-21 Centre Nat Rech Scient Nouveaux derives de cyclodextrines amphiphiles, leur utilisation dans les domaines pharmaceutiques,cosmetiques, alimentaires et leur application a la production de nouveaux nanosystemes
EP3364947B1 (fr) 2015-10-20 2021-09-15 B. Braun Melsungen AG Composition aqueuse comprenant dantrolène

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201783B (en) * 1987-10-13 1990-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing partially methylized carboxy-acyl-beta-cyclodextrines and salts
DE3810737A1 (de) * 1988-03-30 1989-10-12 Macherey Nagel Gmbh & Co Kg Substituierte cyclodextrine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006521403A (ja) * 2003-03-28 2006-09-21 アイバックス コーポレイション クラドリビンの経口製剤

Also Published As

Publication number Publication date
WO1999062958A1 (fr) 1999-12-09
AU3954799A (en) 1999-12-20
EP1084149A1 (fr) 2001-03-21

Similar Documents

Publication Publication Date Title
US5024998A (en) Pharmaceutical formulations for parenteral use
JP2722277B2 (ja) 水溶解性の高いシクロデキストリン誘導体組成物及びその用途
AU2006285678B2 (en) Anticancer agent
EP0335545B1 (fr) Formulations pharmaceutiques pour l'usage parentéral
ES2298510T3 (es) Microemulsiones polimericas.
JP2003532757A (ja) アシル化シクロデキストリン：ゲスト分子包接錯体
CA2209862A1 (fr) Composition pharmaceutique renfermant une cyclodextrine acylee
EP2194068A1 (fr) Composé de cyclodextrine modifié par l'acide folique, procédé pour le produire, agent de délivrance de médicament pour le ciblage d'un système de délivrance de médicament, composition pharmaceutique et agent d'imagerie
WO2003043602A1 (fr) Dispersions solides contenant de la cyclodextrine substituee et un medicament insoluble et preparations afferentes
US9364546B2 (en) Melt-extruded composition comprising a cellulose ether
IE890810L (en) Pharmaceutical formulations for parenteral use
PL195280B1 (pl) Kompleks inhibitora RAS-farnezylotransferazy o ulepszonej rozpuszczalności w wodzie i trwałości oraz kompozycja inhibitora RAS-farnezylotransferazy
JP2002517521A (ja) アシル化アルキル化シクロデキストリン誘導体及びその薬物担体としての使用
GB2109381A (en) Inclusion complexes of steroids with delta -cyclodextrin
Lemesle-Lamache et al. Study of β-cyclodextrin and ethylated β-cyclodextrin salbutamol complexes, in vitro evaluation of sustained-release behaviour of salbutamol
CN109153735A (zh) 基于环糊精的聚合物、其方法、组合物和应用
CN112618729A (zh) 一种雷公藤红素-壳寡糖偶联药物的制备方法及其应用
JPH07165616A (ja) シクロデキストリンの複合組成物及び複合化法
Ansari et al. Cyclodextrin and its Derivative in Drug Delivery System
JPS6130551A (ja) ４−ビフエニリル酢酸−シクロデキストリン包接化合物
Duchêne New trends in pharmaceutical applications of cyclodextrin inclusion compounds
TWI283583B (en) Cyclodextrin-drospirenone inclusion complexes
CH₂OH et al. BIOMEDICAL USES OF AMORPHOUS WATER-SOLUBLE DERIVATIVES OF CYCLODEXTRINS
Bertolla Monofunctionalizations of beta-cyclodextrin, conjugation with recognition patterns, and biological evaluation
PT99146B (pt) Processo para a preparacao de complexos de inclusao com silibinina e de composicoes farmaceuticas que os contem

Legal Events

Date Code Title Description
A300 Withdrawal of application because of no request for examination

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 20060801