JP2002514055A - ガラニンｇａｌｒ３受容体をコードするｄｎａおよびその使用 - Google Patents
ガラニンｇａｌｒ３受容体をコードするｄｎａおよびその使用Info
- Publication number
- JP2002514055A JP2002514055A JP51773898A JP51773898A JP2002514055A JP 2002514055 A JP2002514055 A JP 2002514055A JP 51773898 A JP51773898 A JP 51773898A JP 51773898 A JP51773898 A JP 51773898A JP 2002514055 A JP2002514055 A JP 2002514055A
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- galr3
- galr3 receptor
- cells
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72813996A | 1996-10-09 | 1996-10-09 | |
| US08/728,139 | 1996-10-09 | ||
| US76796496A | 1996-12-17 | 1996-12-17 | |
| US08/767,964 | 1996-12-17 | ||
| US78726197A | 1997-01-24 | 1997-01-24 | |
| US08/787,261 | 1997-01-24 | ||
| US08/900,230 US6329197B2 (en) | 1996-10-09 | 1997-07-23 | DNA encoding galanin GALR3 receptors and uses thereof |
| US08/900,230 | 1997-07-23 | ||
| PCT/US1997/018222 WO1998015570A1 (en) | 1996-10-09 | 1997-10-09 | Dna encoding galanin galr3 receptors and uses thereof |
Publications (2)
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| JP2002514055A true JP2002514055A (ja) | 2002-05-14 |
| JP2002514055A5 JP2002514055A5 (enExample) | 2005-06-16 |
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| US (5) | US6329197B2 (enExample) |
| EP (1) | EP0956291A4 (enExample) |
| JP (1) | JP2002514055A (enExample) |
| AU (1) | AU741041B2 (enExample) |
| CA (1) | CA2248222A1 (enExample) |
| DE (1) | DE956291T1 (enExample) |
| ES (1) | ES2151465T1 (enExample) |
| WO (1) | WO1998015570A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6329197B2 (en) * | 1996-10-09 | 2001-12-11 | Synaptic Pharmaceutical Corporation | DNA encoding galanin GALR3 receptors and uses thereof |
| US20030119096A1 (en) * | 1997-01-24 | 2003-06-26 | Bard Jonathan A. | Method of treating an abnormality using a GALR3 receptor antagonist |
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6693182B1 (en) * | 1997-08-22 | 2004-02-17 | Schering Corporation | Mammalian galanin receptors |
| CA2326694A1 (en) * | 1997-12-17 | 1999-06-24 | Merck & Co., Inc. | Galanin receptor galr3 and nucleotides encoding same |
| US6395877B1 (en) | 1998-06-30 | 2002-05-28 | Millennium Pharmaceuticals, Inc. | 14273 receptor, a novel G-protein coupled receptor |
| EP1092024A2 (en) | 1998-06-30 | 2001-04-18 | Millennium Pharmaceuticals, Inc. | 14273 receptor, a g-protein coupled receptor |
| US6448005B1 (en) | 1998-06-30 | 2002-09-10 | Millennium Pharmaceuticals, Inc. | 14723 Receptor, a novel G-protein coupled receptor |
| US7534579B2 (en) | 1998-06-30 | 2009-05-19 | Millennium Pharmaceuticals, Inc. | 14273 receptor, a novel G-protein coupled receptor |
| US6221613B1 (en) | 1998-12-31 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
| ATE342979T1 (de) | 1999-08-03 | 2006-11-15 | Millennium Pharm Inc | 15571, ein neues gpcr-ähnliches molekül der secretin-ähnlichen familie und dessen verwendungen |
| WO2001087930A2 (en) * | 2000-05-18 | 2001-11-22 | Bayer Aktiengesellschaft | Human galanin receptor-like g protein coupled receptor |
| US20040127502A1 (en) * | 2001-01-31 | 2004-07-01 | Synaptic Pharmaceutical Corporation | Use of GAL3 antagonist for treatment of depression |
| US7081470B2 (en) * | 2001-01-31 | 2006-07-25 | H. Lundbeck A/S | Use of GALR3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods |
| IL157102A0 (en) | 2001-01-31 | 2004-02-08 | Synaptic Pharma Corp | Use of gal3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods |
| JP2005507654A (ja) * | 2001-08-27 | 2005-03-24 | トゥラリック インコーポレイテッド | 増幅した癌遺伝子およびそれらの癌への関与 |
| AU2003259759A1 (en) * | 2002-08-07 | 2004-02-25 | Synaptic Pharmaceutical Corporation | Gal3 receptor antagonists for the treatment of affective disorders |
| US7642281B2 (en) * | 2002-08-07 | 2010-01-05 | Helicon Therapeutics, Inc. | Indolone compounds useful to treat cognitive impairment |
| US7220775B2 (en) | 2002-08-07 | 2007-05-22 | H. Lundbeck A/S | Compound useful for the treatment of neuropathic pain |
| AU2005299771A1 (en) * | 2004-10-21 | 2006-05-04 | High Point Pharmaceuticals, Llc | Bissulfonamide compounds as agonists of GalR1, compositions, and methods of use |
| EP2636757B1 (en) * | 2008-05-27 | 2016-11-23 | Dako Denmark A/S | Compositions and methods for detection of chromosomal aberrations with novel hybridization buffers |
| US9303287B2 (en) | 2009-02-26 | 2016-04-05 | Dako Denmark A/S | Compositions and methods for RNA hybridization applications |
| US20100284977A1 (en) * | 2009-04-28 | 2010-11-11 | University Of South Carolina | Expression of Anti-Nociceptive Compounds from Endogenously Regulated Promoters |
| EP2647722B1 (en) * | 2010-12-03 | 2016-07-06 | Tsumura & Co. | Daikenchuto bioassay method and quality management method using same |
| WO2013046033A1 (en) | 2011-09-30 | 2013-04-04 | Dako Denmark A/S | Hybridization compositions and methods using formamide |
| EP3252173A1 (en) | 2011-10-21 | 2017-12-06 | Dako Denmark A/S | Hybridization compositions and methods |
| US9879254B2 (en) | 2012-01-18 | 2018-01-30 | The General Hosptial Corporation | Targeting RNAs to microvesicles |
| KR101514440B1 (ko) * | 2013-12-13 | 2015-04-22 | 고려대학교 산학협력단 | 갈라닌 수용체 3형의 리간드로서 스펙신의 용도 |
| CN113512592A (zh) * | 2021-04-23 | 2021-10-19 | 中国科学院深圳先进技术研究院 | 用于检测甘丙肽分泌细胞的引物、探针以及试剂盒 |
| EP4626454A1 (en) * | 2022-11-29 | 2025-10-08 | Neuracle Science Co., Ltd. | Use of galr2 agonists to treat gastrointestinal and/or endocrine disorders |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5462856A (en) | 1990-07-19 | 1995-10-31 | Bunsen Rush Laboratories, Inc. | Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins |
| US5401629A (en) | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| JPH06510363A (ja) | 1990-10-29 | 1994-11-17 | ディカルブ プラント ジェネティクス | 磁気性粒子を使用する生物学的材料の単離 |
| WO1992012997A1 (en) | 1991-01-16 | 1992-08-06 | The General Hospital Corporation | Human galanin |
| WO1992015015A1 (en) | 1991-02-25 | 1992-09-03 | Zymogenetic, Inc. | Methods for detecting galanin antagonists |
| WO1992015681A1 (en) | 1991-03-06 | 1992-09-17 | Garvan Institute Of Medical Research | HUMAN GALANIN, cDNA CLONES ENCODING HUMAN GALANIN AND A METHOD OF PRODUCING HUMAN GALANIN |
| US5576296A (en) | 1991-05-15 | 1996-11-19 | Aktiebolaget Astra | Galanin antagonist |
| SE9101472D0 (sv) | 1991-05-15 | 1991-05-15 | Trion Forskning & Utveckling | Galanin antagonist |
| US5436155A (en) | 1991-12-31 | 1995-07-25 | Arch Development Corporation | Isolated DNA encoding a somatostatin receptor |
| US5290808A (en) | 1992-11-06 | 1994-03-01 | Carter-Wallace, Inc. | Method to control the intake of food |
| FR2716205B1 (fr) | 1994-02-17 | 1996-04-12 | Rhone Poulenc Rorer Sa | Récepteur galanine, acides nucléiques, cellules transformées et utilisations. |
| US6399325B1 (en) | 1994-10-13 | 2002-06-04 | Takeda Chemical Industries, Ltd. | DNA encoding a galanin receptor |
| US6562862B1 (en) | 1994-10-20 | 2003-05-13 | Eli Lilly And Company | Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y |
| US6410686B1 (en) | 1996-06-05 | 2002-06-25 | Bayer Corporation | Galanin receptor 2 protein |
| SE9602822D0 (sv) | 1996-07-19 | 1996-07-19 | Astra Pharma Inc | New receptor |
| PT1342410E (pt) | 1996-07-24 | 2010-05-11 | Neurotargets Ltd | Utilização de um agonista de galanina na preparação de um medicamento para melhorar a memória e outras funções cognitivas |
| US6329197B2 (en) | 1996-10-09 | 2001-12-11 | Synaptic Pharmaceutical Corporation | DNA encoding galanin GALR3 receptors and uses thereof |
| CA2326694A1 (en) | 1997-12-17 | 1999-06-24 | Merck & Co., Inc. | Galanin receptor galr3 and nucleotides encoding same |
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1997
- 1997-07-23 US US08/900,230 patent/US6329197B2/en not_active Expired - Fee Related
- 1997-10-09 JP JP51773898A patent/JP2002514055A/ja not_active Withdrawn
- 1997-10-09 AU AU48125/97A patent/AU741041B2/en not_active Ceased
- 1997-10-09 CA CA002248222A patent/CA2248222A1/en not_active Abandoned
- 1997-10-09 EP EP19970910850 patent/EP0956291A4/en not_active Withdrawn
- 1997-10-09 ES ES97910850T patent/ES2151465T1/es active Pending
- 1997-10-09 DE DE0956291T patent/DE956291T1/de active Pending
- 1997-10-09 WO PCT/US1997/018222 patent/WO1998015570A1/en not_active Ceased
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1998
- 1998-04-09 US US09/058,333 patent/US6368812B1/en not_active Expired - Fee Related
- 1998-11-25 US US09/199,737 patent/US6287788B1/en not_active Expired - Fee Related
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2001
- 2001-01-26 US US09/771,287 patent/US20030082641A1/en not_active Abandoned
- 2001-12-03 US US10/007,132 patent/US7022489B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0956291A1 (en) | 1999-11-17 |
| EP0956291A4 (en) | 2002-10-24 |
| WO1998015570A1 (en) | 1998-04-16 |
| AU741041B2 (en) | 2001-11-22 |
| ES2151465T1 (es) | 2001-01-01 |
| US6329197B2 (en) | 2001-12-11 |
| US20010009766A1 (en) | 2001-07-26 |
| US20030027254A1 (en) | 2003-02-06 |
| DE956291T1 (de) | 2001-05-23 |
| US7022489B2 (en) | 2006-04-04 |
| AU4812597A (en) | 1998-05-05 |
| US6287788B1 (en) | 2001-09-11 |
| US6368812B1 (en) | 2002-04-09 |
| CA2248222A1 (en) | 1998-04-16 |
| US20030082641A1 (en) | 2003-05-01 |
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