JP2002513916A - 単層を利用する被検体の電子的検出方法 - Google Patents
単層を利用する被検体の電子的検出方法Info
- Publication number
- JP2002513916A JP2002513916A JP2000547268A JP2000547268A JP2002513916A JP 2002513916 A JP2002513916 A JP 2002513916A JP 2000547268 A JP2000547268 A JP 2000547268A JP 2000547268 A JP2000547268 A JP 2000547268A JP 2002513916 A JP2002513916 A JP 2002513916A
- Authority
- JP
- Japan
- Prior art keywords
- probe
- preferred
- etm
- nucleic acid
- capture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2610/00—Assays involving self-assembled monolayers [SAMs]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Materials Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8450998P | 1998-05-06 | 1998-05-06 | |
| US8465298P | 1998-05-06 | 1998-05-06 | |
| US60/084,652 | 1998-05-06 | ||
| US13518398A | 1998-08-17 | 1998-08-17 | |
| US09/135,183 | 1998-08-17 | ||
| US60/084,509 | 1998-08-17 | ||
| PCT/US1999/010104 WO1999057317A1 (en) | 1998-05-06 | 1999-05-06 | Electronic methods for the detection of analytes utilizing monolayers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002513916A true JP2002513916A (ja) | 2002-05-14 |
| JP2002513916A5 JP2002513916A5 (enExample) | 2006-06-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000547268A Pending JP2002513916A (ja) | 1998-05-06 | 1999-05-06 | 単層を利用する被検体の電子的検出方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6600026B1 (enExample) |
| EP (1) | EP1075549B1 (enExample) |
| JP (1) | JP2002513916A (enExample) |
| AT (1) | ATE407220T1 (enExample) |
| AU (1) | AU763494B2 (enExample) |
| CA (1) | CA2331189A1 (enExample) |
| DE (1) | DE69939464D1 (enExample) |
| WO (1) | WO1999057317A1 (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
| US7393645B2 (en) * | 1996-11-05 | 2008-07-01 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
| US7160678B1 (en) * | 1996-11-05 | 2007-01-09 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
| US6013459A (en) * | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
| CA2293744A1 (en) * | 1997-06-12 | 1998-12-17 | Clinical Micro Sensors, Inc. | Electronic methods for the detection of analytes |
| JP2002500897A (ja) | 1998-01-27 | 2002-01-15 | クリニカル・マイクロ・センサーズ・インコーポレイテッド | 電子的核酸検出の増幅 |
| US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
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- 1999-05-06 WO PCT/US1999/010104 patent/WO1999057317A1/en not_active Ceased
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| AU763494B2 (en) | 2003-07-24 |
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| CA2331189A1 (en) | 1999-11-11 |
| DE69939464D1 (de) | 2008-10-16 |
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