AU763494B2 - Electronic methods for the detection of analytes utilizing monolayers - Google Patents

Electronic methods for the detection of analytes utilizing monolayers Download PDF

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Publication number
AU763494B2
AU763494B2 AU40725/99A AU4072599A AU763494B2 AU 763494 B2 AU763494 B2 AU 763494B2 AU 40725/99 A AU40725/99 A AU 40725/99A AU 4072599 A AU4072599 A AU 4072599A AU 763494 B2 AU763494 B2 AU 763494B2
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AU
Australia
Prior art keywords
preferred
nucleic acid
probe
electrode
probes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU40725/99A
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English (en)
Other versions
AU4072599A (en
Inventor
Changjun Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clinical Micro Sensors Inc
Original Assignee
Clinical Micro Sensors Inc
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Filing date
Publication date
Application filed by Clinical Micro Sensors Inc filed Critical Clinical Micro Sensors Inc
Publication of AU4072599A publication Critical patent/AU4072599A/en
Application granted granted Critical
Publication of AU763494B2 publication Critical patent/AU763494B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2610/00Assays involving self-assembled monolayers [SAMs]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AU40725/99A 1998-05-06 1999-05-06 Electronic methods for the detection of analytes utilizing monolayers Ceased AU763494B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US8450998P 1998-05-06 1998-05-06
US8465298P 1998-05-06 1998-05-06
US60/084652 1998-05-06
US60/084509 1998-05-06
US13518398A 1998-08-17 1998-08-17
US09/135183 1998-08-17
PCT/US1999/010104 WO1999057317A1 (en) 1998-05-06 1999-05-06 Electronic methods for the detection of analytes utilizing monolayers

Publications (2)

Publication Number Publication Date
AU4072599A AU4072599A (en) 1999-11-23
AU763494B2 true AU763494B2 (en) 2003-07-24

Family

ID=27374792

Family Applications (1)

Application Number Title Priority Date Filing Date
AU40725/99A Ceased AU763494B2 (en) 1998-05-06 1999-05-06 Electronic methods for the detection of analytes utilizing monolayers

Country Status (8)

Country Link
US (1) US6600026B1 (enExample)
EP (1) EP1075549B1 (enExample)
JP (1) JP2002513916A (enExample)
AT (1) ATE407220T1 (enExample)
AU (1) AU763494B2 (enExample)
CA (1) CA2331189A1 (enExample)
DE (1) DE69939464D1 (enExample)
WO (1) WO1999057317A1 (enExample)

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Also Published As

Publication number Publication date
EP1075549B1 (en) 2008-09-03
CA2331189A1 (en) 1999-11-11
WO1999057317A1 (en) 1999-11-11
ATE407220T1 (de) 2008-09-15
AU4072599A (en) 1999-11-23
WO1999057317A9 (en) 2000-02-17
US6600026B1 (en) 2003-07-29
EP1075549A1 (en) 2001-02-14
JP2002513916A (ja) 2002-05-14
DE69939464D1 (de) 2008-10-16

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