CA2331189A1 - Electronic methods for the detection of analytes utilizing monolayers - Google Patents
Electronic methods for the detection of analytes utilizing monolayers Download PDFInfo
- Publication number
- CA2331189A1 CA2331189A1 CA002331189A CA2331189A CA2331189A1 CA 2331189 A1 CA2331189 A1 CA 2331189A1 CA 002331189 A CA002331189 A CA 002331189A CA 2331189 A CA2331189 A CA 2331189A CA 2331189 A1 CA2331189 A1 CA 2331189A1
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- CA
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- Prior art keywords
- preferred
- nucleic acid
- electrode
- probe
- capture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2610/00—Assays involving self-assembled monolayers [SAMs]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Materials Engineering (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8465298P | 1998-05-06 | 1998-05-06 | |
| US8450998P | 1998-05-06 | 1998-05-06 | |
| US60/084,652 | 1998-05-06 | ||
| US60/084,509 | 1998-05-06 | ||
| US13518398A | 1998-08-17 | 1998-08-17 | |
| US09/135,183 | 1998-08-17 | ||
| PCT/US1999/010104 WO1999057317A1 (en) | 1998-05-06 | 1999-05-06 | Electronic methods for the detection of analytes utilizing monolayers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2331189A1 true CA2331189A1 (en) | 1999-11-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002331189A Abandoned CA2331189A1 (en) | 1998-05-06 | 1999-05-06 | Electronic methods for the detection of analytes utilizing monolayers |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6600026B1 (enExample) |
| EP (1) | EP1075549B1 (enExample) |
| JP (1) | JP2002513916A (enExample) |
| AT (1) | ATE407220T1 (enExample) |
| AU (1) | AU763494B2 (enExample) |
| CA (1) | CA2331189A1 (enExample) |
| DE (1) | DE69939464D1 (enExample) |
| WO (1) | WO1999057317A1 (enExample) |
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| US7381525B1 (en) * | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
| US7160678B1 (en) * | 1996-11-05 | 2007-01-09 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
| US7393645B2 (en) * | 1996-11-05 | 2008-07-01 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
| US6013459A (en) * | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
| WO1998057159A1 (en) * | 1997-06-12 | 1998-12-17 | Clinical Micro Sensors, Inc. | Electronic methods for the detection of analytes |
| US7090804B2 (en) | 1998-01-27 | 2006-08-15 | Clinical Mirco Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
| US6761816B1 (en) | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
| US6740518B1 (en) | 1998-09-17 | 2004-05-25 | Clinical Micro Sensors, Inc. | Signal detection techniques for the detection of analytes |
| AU1241000A (en) * | 1998-10-27 | 2000-05-15 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
| US6833267B1 (en) * | 1998-12-30 | 2004-12-21 | Clinical Micro Sensors, Inc. | Tissue collection devices containing biosensors |
| US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
| US20040053290A1 (en) * | 2000-01-11 | 2004-03-18 | Terbrueggen Robert Henry | Devices and methods for biochip multiplexing |
| US7312087B2 (en) | 2000-01-11 | 2007-12-25 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US20020177135A1 (en) | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
| US6361958B1 (en) * | 1999-11-12 | 2002-03-26 | Motorola, Inc. | Biochannel assay for hybridization with biomaterial |
| WO2001083826A2 (en) * | 2000-05-03 | 2001-11-08 | Massachusetts Institute Of Technology | Methods and reagents for assembling molecules on solid supports |
| JP4382265B2 (ja) * | 2000-07-12 | 2009-12-09 | 日本電気株式会社 | 酸化シリコン膜の形成方法及びその形成装置 |
| GB0205455D0 (en) | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
| EP1466663A1 (en) * | 2003-03-19 | 2004-10-13 | F. Hoffmann-La Roche Ag | Quality control method for manufacturing nucleic acid arrays |
| US8003374B2 (en) | 2003-03-25 | 2011-08-23 | The Regents Of The University Of California | Reagentless, reusable, bioelectronic detectors |
| US7597793B2 (en) | 2003-06-20 | 2009-10-06 | Roche Operations Ltd. | System and method for analyte measurement employing maximum dosing time delay |
| US7452457B2 (en) | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
| US7604721B2 (en) | 2003-06-20 | 2009-10-20 | Roche Diagnostics Operations, Inc. | System and method for coding information on a biosensor test strip |
| US7556723B2 (en) | 2004-06-18 | 2009-07-07 | Roche Diagnostics Operations, Inc. | Electrode design for biosensor |
| US7569126B2 (en) | 2004-06-18 | 2009-08-04 | Roche Diagnostics Operations, Inc. | System and method for quality assurance of a biosensor test strip |
| US20060068870A1 (en) * | 2004-09-13 | 2006-03-30 | Pokertek, Inc. | Electronic card table and method with host console |
| EP1954838B1 (en) * | 2005-11-14 | 2014-02-26 | Life Technologies Corporation | Coded molecules for detecting target analytes |
| US7803542B2 (en) | 2005-11-29 | 2010-09-28 | The Regents Of The University Of California | Signal-on architecture for electronic, oligonucleotide-based detectors |
| JP5352742B2 (ja) | 2009-08-07 | 2013-11-27 | オームクス コーポレーション | 酵素による酸化還元変化化学的脱離(e−trace)免疫学的検定法 |
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1999
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- 1999-05-06 EP EP99924156A patent/EP1075549B1/en not_active Expired - Lifetime
- 1999-05-06 AU AU40725/99A patent/AU763494B2/en not_active Ceased
- 1999-05-06 JP JP2000547268A patent/JP2002513916A/ja active Pending
- 1999-05-06 CA CA002331189A patent/CA2331189A1/en not_active Abandoned
- 1999-05-06 DE DE69939464T patent/DE69939464D1/de not_active Expired - Lifetime
- 1999-05-06 WO PCT/US1999/010104 patent/WO1999057317A1/en not_active Ceased
- 1999-05-06 AT AT99924156T patent/ATE407220T1/de not_active IP Right Cessation
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| EP1075549A1 (en) | 2001-02-14 |
| ATE407220T1 (de) | 2008-09-15 |
| US6600026B1 (en) | 2003-07-29 |
| WO1999057317A1 (en) | 1999-11-11 |
| AU4072599A (en) | 1999-11-23 |
| EP1075549B1 (en) | 2008-09-03 |
| JP2002513916A (ja) | 2002-05-14 |
| AU763494B2 (en) | 2003-07-24 |
| DE69939464D1 (de) | 2008-10-16 |
| WO1999057317A9 (en) | 2000-02-17 |
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