JP2002513156A5 - - Google Patents

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Publication number
JP2002513156A5
JP2002513156A5 JP2000546239A JP2000546239A JP2002513156A5 JP 2002513156 A5 JP2002513156 A5 JP 2002513156A5 JP 2000546239 A JP2000546239 A JP 2000546239A JP 2000546239 A JP2000546239 A JP 2000546239A JP 2002513156 A5 JP2002513156 A5 JP 2002513156A5
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JP
Japan
Prior art keywords
phage display
library
internalized
display library
target cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000546239A
Other languages
English (en)
Japanese (ja)
Other versions
JP4493845B2 (ja
JP2002513156A (ja
Filing date
Publication date
Priority claimed from US09/249,529 external-priority patent/US6794128B2/en
Application filed filed Critical
Publication of JP2002513156A publication Critical patent/JP2002513156A/ja
Publication of JP2002513156A5 publication Critical patent/JP2002513156A5/ja
Application granted granted Critical
Publication of JP4493845B2 publication Critical patent/JP4493845B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2000546239A 1998-04-24 1999-04-22 インターナライズする抗体を選択する方法 Expired - Fee Related JP4493845B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8295398P 1998-04-24 1998-04-24
US60/082,953 1998-04-24
US09/249,529 1999-02-12
US09/249,529 US6794128B2 (en) 1998-04-24 1999-02-12 Methods of selecting internalizing antibodies
PCT/US1999/008468 WO1999056129A1 (en) 1998-04-24 1999-04-22 Methods of selecting internalizing antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009170482A Division JP2009278993A (ja) 1998-04-24 2009-07-21 インターナライズする抗体を選択する方法

Publications (3)

Publication Number Publication Date
JP2002513156A JP2002513156A (ja) 2002-05-08
JP2002513156A5 true JP2002513156A5 (cg-RX-API-DMAC7.html) 2006-05-25
JP4493845B2 JP4493845B2 (ja) 2010-06-30

Family

ID=26768026

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000546239A Expired - Fee Related JP4493845B2 (ja) 1998-04-24 1999-04-22 インターナライズする抗体を選択する方法
JP2009170482A Pending JP2009278993A (ja) 1998-04-24 2009-07-21 インターナライズする抗体を選択する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009170482A Pending JP2009278993A (ja) 1998-04-24 2009-07-21 インターナライズする抗体を選択する方法

Country Status (8)

Country Link
US (3) US6794128B2 (cg-RX-API-DMAC7.html)
EP (1) EP1073905B1 (cg-RX-API-DMAC7.html)
JP (2) JP4493845B2 (cg-RX-API-DMAC7.html)
AT (1) ATE525385T1 (cg-RX-API-DMAC7.html)
AU (1) AU768784B2 (cg-RX-API-DMAC7.html)
CA (1) CA2326499C (cg-RX-API-DMAC7.html)
DK (1) DK1073905T3 (cg-RX-API-DMAC7.html)
WO (1) WO1999056129A1 (cg-RX-API-DMAC7.html)

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US7563874B2 (en) * 1998-08-31 2009-07-21 The Regents Of The University Of California Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
US9034330B2 (en) * 1999-02-22 2015-05-19 Georgetown University Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof
US7780882B2 (en) * 1999-02-22 2010-08-24 Georgetown University Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent
JP4799736B2 (ja) * 1999-02-22 2011-10-26 ジョージタウン・ユニバーシティ 全身性遺伝子送達のための抗体フラグメント標的化イムノリポソーム
US9034329B2 (en) * 1999-02-22 2015-05-19 Georgetown University Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof
IL144559A0 (en) 1999-03-01 2002-05-23 Genentech Inc Antibodies for cancer therapy and diagnosis
US7045283B2 (en) * 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
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US20030104402A1 (en) * 2001-01-23 2003-06-05 University Of Rochester Methods of producing or identifying intrabodies in eukaryotic cells
JP2004537280A (ja) * 2001-03-07 2004-12-16 ゼノジェン コーポレイション 標的細胞中へのｄｎａの導入についてのスクリーニング方法
US20030194798A1 (en) * 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
ITRM20010408A1 (it) * 2001-07-10 2003-01-10 Univ Napoli Federico Ii Mini-anticorpo umano citotossico per cellule tumorali che esprimono il recettore erbb2.
US20030073104A1 (en) * 2001-10-02 2003-04-17 Belcher Angela M. Nanoscaling ordering of hybrid materials using genetically engineered mesoscale virus
US7452539B2 (en) * 2001-12-19 2008-11-18 Genentech, Inc. Stabilizing polypeptides which have been exposed to urea
US7332585B2 (en) * 2002-04-05 2008-02-19 The Regents Of The California University Bispecific single chain Fv antibody molecules and methods of use thereof
US7332580B2 (en) * 2002-04-05 2008-02-19 The Regents Of The University Of California Bispecific single chain Fv antibody molecules and methods of use thereof
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US20050064508A1 (en) * 2003-09-22 2005-03-24 Semzyme Peptide mediated synthesis of metallic and magnetic materials
US9701754B1 (en) * 2002-10-23 2017-07-11 City Of Hope Covalent disulfide-linked diabodies and uses thereof
ES2374822T3 (es) * 2004-02-24 2012-02-22 Allergan, Inc. Ensayo de selección de toxinas botul�?nicas.
EP2153848A3 (en) * 2005-01-27 2010-07-21 The Regents of the University of California Therapeutic monoclonal antibodies that neutralize botulinium neurotoxins
MX2007013200A (es) * 2005-04-22 2008-03-24 Johnson & Johnson Composicion de inmunoliposoma para el direccionamiento hacia un receptor de la celula her2.
US20100041874A1 (en) * 2006-10-03 2010-02-18 Genmab A/S High throughput methods for characterization of antibodies
WO2008053486A1 (en) * 2006-11-02 2008-05-08 Sylvie Luria Methods for screening for therapeutic molecules and use of the molecules therefrom
WO2008140493A2 (en) * 2006-11-21 2008-11-20 The Regents Of The University Of Californina Anti-egfr family antibodies, bispecific anti-egfr family antibodies and methods of use thereof
WO2009008916A2 (en) 2007-03-22 2009-01-15 The Regents Of The University Of Californina Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
US20090175784A1 (en) 2007-05-11 2009-07-09 Joshua Goldstein Anti-Alpha V Immunoliposome Composition, Methods, and Uses
CA2692546C (en) * 2007-07-09 2018-03-13 Esther H. Chang Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery
US9000131B2 (en) * 2008-07-31 2015-04-07 The Regents Of The University Of California Antibodies that neutralize botulinum neurotoxins
RU2011131071A (ru) * 2008-12-26 2013-02-10 Дзе Юниверсити Оф Токио Диагностика и лечение рака с помощью антитела против lgr7
CN102884084B (zh) * 2010-03-04 2016-12-07 西福根有限公司 抗her2抗体及组合物
US8609095B2 (en) 2010-03-04 2013-12-17 Symphogen A/S Anti-HER2 antibodies and compositions
US9243057B2 (en) 2010-08-31 2016-01-26 The Regents Of The University Of California Antibodies for botulinum neurotoxins
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US9097721B2 (en) 2012-02-29 2015-08-04 The Board Of Trustees Of The University Of Illinois Compositions comprising engineered phosphothreonine affinity reagents, methods of making, and methods of use
MY191368A (en) 2013-06-28 2022-06-20 X Body Inc Target antigen discovery, phenotypic screens and use thereof for identification of target cell specific target epitopes
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WO2019106694A1 (en) 2017-11-30 2019-06-06 University Of Delhi South Campus An antibody fragment library, and uses thereof
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NL2038054B1 (en) 2024-06-25 2026-01-15 Academisch Ziekenhuis Leiden A method for preparing liposomes

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