JP2002512194A5 - - Google Patents
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- Publication number
- JP2002512194A5 JP2002512194A5 JP2000544332A JP2000544332A JP2002512194A5 JP 2002512194 A5 JP2002512194 A5 JP 2002512194A5 JP 2000544332 A JP2000544332 A JP 2000544332A JP 2000544332 A JP2000544332 A JP 2000544332A JP 2002512194 A5 JP2002512194 A5 JP 2002512194A5
- Authority
- JP
- Japan
- Prior art keywords
- nsaid
- supplement
- vitamin
- therapeutic agent
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 20
- RADKZDMFGJYCBB-UHFFFAOYSA-N Pyridoxal Chemical compound CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 12
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 10
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 10
- 229940011671 vitamin b6 Drugs 0.000 description 10
- 239000013589 supplement Substances 0.000 description 8
- 235000019158 vitamin B6 Nutrition 0.000 description 8
- 239000011726 vitamin B6 Substances 0.000 description 8
- 239000003814 drug Substances 0.000 description 7
- 229940124597 therapeutic agent Drugs 0.000 description 7
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 6
- NHZMQXZHNVQTQA-UHFFFAOYSA-N pyridoxamine Chemical compound CC1=NC=C(CO)C(CN)=C1O NHZMQXZHNVQTQA-UHFFFAOYSA-N 0.000 description 4
- 206010020772 Hypertension Diseases 0.000 description 3
- 229960001259 diclofenac Drugs 0.000 description 3
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 description 3
- 229960000905 indomethacin Drugs 0.000 description 3
- RDJGLLICXDHJDY-NSHDSACASA-N (2s)-2-(3-phenoxyphenyl)propanoic acid Chemical compound OC(=O)[C@@H](C)C1=CC=CC(OC=2C=CC=CC=2)=C1 RDJGLLICXDHJDY-NSHDSACASA-N 0.000 description 2
- BUZICZZQJDLXJN-UHFFFAOYSA-N 3-azaniumyl-4-hydroxybutanoate Chemical compound OCC(N)CC(O)=O BUZICZZQJDLXJN-UHFFFAOYSA-N 0.000 description 2
- BSYNRYMUTXBXSQ-FOQJRBATSA-N 59096-14-9 Chemical compound CC(=O)OC1=CC=CC=C1[14C](O)=O BSYNRYMUTXBXSQ-FOQJRBATSA-N 0.000 description 2
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 2
- CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 229960005142 alclofenac Drugs 0.000 description 2
- ARHWPKZXBHOEEE-UHFFFAOYSA-N alclofenac Chemical compound OC(=O)CC1=CC=C(OCC=C)C(Cl)=C1 ARHWPKZXBHOEEE-UHFFFAOYSA-N 0.000 description 2
- -1 aluminoprofen Chemical compound 0.000 description 2
- SOYCMDCMZDHQFP-UHFFFAOYSA-N amfenac Chemical compound NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=CC=C1 SOYCMDCMZDHQFP-UHFFFAOYSA-N 0.000 description 2
- 229950008930 amfenac Drugs 0.000 description 2
- 229960000616 diflunisal Drugs 0.000 description 2
- HUPFGZXOMWLGNK-UHFFFAOYSA-N diflunisal Chemical compound C1=C(O)C(C(=O)O)=CC(C=2C(=CC(F)=CC=2)F)=C1 HUPFGZXOMWLGNK-UHFFFAOYSA-N 0.000 description 2
- SYKQOFCBFHMCJV-UHFFFAOYSA-N ethyl 2-cyano-3-phenylpropanoate Chemical compound CCOC(=O)C(C#N)CC1=CC=CC=C1 SYKQOFCBFHMCJV-UHFFFAOYSA-N 0.000 description 2
- 229960001419 fenoprofen Drugs 0.000 description 2
- 229960001680 ibuprofen Drugs 0.000 description 2
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 description 2
- 229960000991 ketoprofen Drugs 0.000 description 2
- 229960004752 ketorolac Drugs 0.000 description 2
- OZWKMVRBQXNZKK-UHFFFAOYSA-N ketorolac Chemical compound OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 OZWKMVRBQXNZKK-UHFFFAOYSA-N 0.000 description 2
- 229960003464 mefenamic acid Drugs 0.000 description 2
- HYYBABOKPJLUIN-UHFFFAOYSA-N mefenamic acid Chemical compound CC1=CC=CC(NC=2C(=CC=CC=2)C(O)=O)=C1C HYYBABOKPJLUIN-UHFFFAOYSA-N 0.000 description 2
- 229960002009 naproxen Drugs 0.000 description 2
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 description 2
- 229960002895 phenylbutazone Drugs 0.000 description 2
- VYMDGNCVAMGZFE-UHFFFAOYSA-N phenylbutazonum Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 VYMDGNCVAMGZFE-UHFFFAOYSA-N 0.000 description 2
- 229960002702 piroxicam Drugs 0.000 description 2
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 description 2
- 229960003581 pyridoxal Drugs 0.000 description 2
- 235000008164 pyridoxal Nutrition 0.000 description 2
- 239000011674 pyridoxal Substances 0.000 description 2
- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 description 2
- 235000007682 pyridoxal 5'-phosphate Nutrition 0.000 description 2
- 239000011589 pyridoxal 5'-phosphate Substances 0.000 description 2
- 229960001327 pyridoxal phosphate Drugs 0.000 description 2
- 235000008151 pyridoxamine Nutrition 0.000 description 2
- 239000011699 pyridoxamine Substances 0.000 description 2
- 235000008160 pyridoxine Nutrition 0.000 description 2
- 239000011677 pyridoxine Substances 0.000 description 2
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 description 2
- 229960004172 pyridoxine hydrochloride Drugs 0.000 description 2
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 description 2
- 239000011764 pyridoxine hydrochloride Substances 0.000 description 2
- 229960000894 sulindac Drugs 0.000 description 2
- MLKXDPUZXIRXEP-MFOYZWKCSA-N sulindac Chemical compound CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(S(C)=O)C=C1 MLKXDPUZXIRXEP-MFOYZWKCSA-N 0.000 description 2
- 229960001017 tolmetin Drugs 0.000 description 2
- UPSPUYADGBWSHF-UHFFFAOYSA-N tolmetin Chemical compound C1=CC(C)=CC=C1C(=O)C1=CC=C(CC(O)=O)N1C UPSPUYADGBWSHF-UHFFFAOYSA-N 0.000 description 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- ISRODTBNJUAWEJ-UHFFFAOYSA-N amixetrine Chemical compound C=1C=CC=CC=1C(OCCC(C)C)CN1CCCC1 ISRODTBNJUAWEJ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 229960002390 flurbiprofen Drugs 0.000 description 1
- SYTBZMRGLBWNTM-UHFFFAOYSA-N flurbiprofen Chemical compound FC1=CC(C(C(O)=O)C)=CC=C1C1=CC=CC=C1 SYTBZMRGLBWNTM-UHFFFAOYSA-N 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/061,173 | 1998-04-16 | ||
| US09/061,173 US6051587A (en) | 1998-04-16 | 1998-04-16 | Treatment of iatrogenic and age-related hypertension and pharmaceutical compositions useful therein |
| PCT/CA1999/000331 WO1999053928A1 (en) | 1998-04-16 | 1999-04-16 | Treatment of iatrogenic and age-related hypertension and pharmaceutical compositions useful therein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002512194A JP2002512194A (ja) | 2002-04-23 |
| JP2002512194A5 true JP2002512194A5 (https=) | 2006-05-25 |
Family
ID=22034118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000544332A Withdrawn JP2002512194A (ja) | 1998-04-16 | 1999-04-16 | 医原性および年齢関連性高血圧症の治療方法、およびこれに有用な医薬組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6051587A (https=) |
| EP (1) | EP1071430B1 (https=) |
| JP (1) | JP2002512194A (https=) |
| AT (1) | ATE319457T1 (https=) |
| AU (1) | AU765749B2 (https=) |
| BR (1) | BR9909672A (https=) |
| CA (1) | CA2328730C (https=) |
| DE (1) | DE69930243T2 (https=) |
| ES (1) | ES2260906T3 (https=) |
| IL (1) | IL139681A0 (https=) |
| NZ (1) | NZ508142A (https=) |
| WO (1) | WO1999053928A1 (https=) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716858B1 (en) | 1995-08-28 | 2004-04-06 | Kansas University Medical Center | Methods for inhibiting diabetic complications |
| US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
| CA2366602A1 (en) | 1999-03-08 | 2000-09-14 | Medicure Inc. | Pyridoxal analogues for vitamin b-6 disorders |
| CA2376029A1 (en) * | 1999-07-13 | 2001-01-18 | Medicure Inc. | Use of pyridoxin derivatives for the treatment of diabetes and related complications |
| US6677356B1 (en) | 1999-08-24 | 2004-01-13 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
| EP1531157B1 (en) * | 2000-02-29 | 2008-03-19 | Medicure International Inc. | Cardioprotective phosphonates |
| US7442689B2 (en) | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| WO2001064692A1 (en) * | 2000-02-29 | 2001-09-07 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| CA2404329A1 (en) | 2000-03-28 | 2001-10-04 | Medicure International Inc. | Treatment of cerebrovascular disease |
| JP2003530437A (ja) * | 2000-04-13 | 2003-10-14 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ | Ａβ４２低下物質 |
| US6897228B2 (en) * | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
| US6521645B2 (en) | 2000-11-20 | 2003-02-18 | The University Of Kansas Medical Center | Methods for the treatment and prevention of urinary stone disease |
| US20050026874A1 (en) * | 2002-07-29 | 2005-02-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease |
| US7521584B2 (en) * | 2002-07-29 | 2009-04-21 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of disease |
| US20050148517A1 (en) * | 2002-07-29 | 2005-07-07 | Lockwood Samuel F. | Carotenoid ether analogs or derivatives for controlling connexin 43 expression |
| US20050059635A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling C-reactive protein levels |
| US7375133B2 (en) * | 2002-07-29 | 2008-05-20 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
| CN101845009B (zh) | 2002-07-29 | 2012-10-03 | 卡达克斯药物公司 | 用于抑制和改善疾病的类胡萝卜素结构类似物 |
| US7723327B2 (en) | 2002-07-29 | 2010-05-25 | Cardax Pharmaceuticals, Inc. | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease |
| US7320997B2 (en) * | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
| US20050059659A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for controlling C-reactive protein levels |
| US7763649B2 (en) | 2002-07-29 | 2010-07-27 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for controlling connexin 43 expression |
| US20050004235A1 (en) * | 2002-07-29 | 2005-01-06 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease |
| US20050049248A1 (en) * | 2002-07-29 | 2005-03-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for controlling C-reactive protein levels |
| US7345091B2 (en) * | 2002-07-29 | 2008-03-18 | Cardax Pharmaceuticals, Inc. | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
| US20050143475A1 (en) * | 2002-07-29 | 2005-06-30 | Lockwood Samuel F. | Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury |
| WO2004071431A2 (en) * | 2003-02-05 | 2004-08-26 | Myriad Genetics, Inc. | Method and composition for treating neurodegenerative disorders |
| CA2520422A1 (en) * | 2003-03-27 | 2004-10-07 | Medicure Inc. | Compositions for treating angina |
| JP2006523206A (ja) * | 2003-03-27 | 2006-10-12 | メディキュア インコーポレーテッド | 細胞死の調節 |
| KR20060040676A (ko) * | 2003-07-11 | 2006-05-10 | 미리어드 제네틱스, 인크. | 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형 |
| WO2006001877A2 (en) * | 2004-04-13 | 2006-01-05 | Myriad Genetics, Inc. | Combination treatment for neurodegenerative disorders comprising r-flurbiprofen |
| US20060058269A1 (en) * | 2004-04-14 | 2006-03-16 | Lockwood Samuel F | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
| CA2564066A1 (en) * | 2004-04-14 | 2005-11-03 | Hawaii Biotech, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
| AU2005241023A1 (en) * | 2004-04-29 | 2005-11-17 | Keystone Retaining Wall Systems, Inc. | Veneers for walls, retaining walls and the like |
| JP2008505126A (ja) * | 2004-07-07 | 2008-02-21 | メディキュア インターナショナル インコーポレイテッド | 血小板凝集薬を用いる併用療法 |
| AU2005270701A1 (en) * | 2004-08-10 | 2006-02-16 | Medicure International Inc. | Combination therapies employing vitamin B6 related compounds and ACE inhibitors and uses thereof for the treatment of diabetic disorders |
| US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
| WO2006020850A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| BRPI0514303A (pt) * | 2004-08-11 | 2008-06-10 | Myriad Genetics Inc | composição farmacêutica e método para tratar distúrbios neurodegenerativos |
| WO2006020852A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| US20060094749A1 (en) * | 2004-10-28 | 2006-05-04 | Medicure International Inc. | Substituted pyridoxines as anti-platelet agents |
| US7459468B2 (en) * | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
| EP1817288A4 (en) * | 2004-10-28 | 2009-08-26 | Medicure Int Inc | DUAL ANTIPLÄTTCHEN / ANTIKOAGULANS PYRIDOXINANALOGE |
| US20070243249A1 (en) * | 2004-11-26 | 2007-10-18 | Friesen Albert D | Novel formulation of pyridoxal-5'-phosphate and method of preparation |
| JP2008526783A (ja) * | 2005-01-05 | 2008-07-24 | メディキュア・インターナショナル・インコーポレーテッド | トリグリセリドレベルを調節するための化合物及び方法 |
| CA2610502A1 (en) | 2005-03-29 | 2006-10-05 | Cardax Pharmaceuticals, Inc. | Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof |
| CA2503087A1 (en) * | 2005-03-30 | 2006-09-30 | Medicure International Inc. | Intravenous formulations of pyridoxal 5'-phosphate and method of preparation |
| CA2615063A1 (en) * | 2005-07-22 | 2007-02-01 | Myriad Genetics, Inc. | High drug load formulations and dosage forms |
| JP2009517411A (ja) * | 2005-11-28 | 2009-04-30 | メディキュア インターナショナル インコーポレーテッド | 心血管及び関連病状の処置のための調剤 |
| DOP2007000055A (es) | 2006-04-10 | 2007-10-31 | Senosiain S A De C V Lab | Composición farmaceutica que comprende un analgésico y vitaminas |
| WO2008006099A2 (en) * | 2006-07-07 | 2008-01-10 | Myriad Genetics, Inc. | Treatment of psychiatric disorders |
| MX2008003230A (es) * | 2008-03-07 | 2009-09-07 | Senosiain S A De C V Lab | Composicion famaceutica oral que comprende la combinacion de una sal de ketorolaco y vitaminas del complejo b. |
| ITMI20121316A1 (it) | 2012-07-27 | 2014-01-28 | Altergon Sa | Complessi di condroitina ad assorbimento transcutaneo |
| EP2908858B1 (en) * | 2012-10-19 | 2020-06-24 | New York University | Compositions for use in inhibiting osteolysis |
| RU2629367C1 (ru) * | 2016-11-02 | 2017-08-29 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Нестероидное противовоспалительное средство на основе напроксена, обладающее низкой гастротоксичностью |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR4492M (https=) * | 1965-07-07 | 1966-10-10 | ||
| FR6707M (https=) * | 1966-04-29 | 1969-02-17 | ||
| FR6723M (https=) * | 1966-12-30 | 1969-02-17 | ||
| FR7503M (https=) * | 1967-05-30 | 1969-12-08 | ||
| GB1236531A (en) * | 1969-02-12 | 1971-06-23 | Soc D Etudes Prod Chimique | Adenin derivative |
| JPS53121765A (en) * | 1977-04-01 | 1978-10-24 | Chugai Pharmaceut Co Ltd | Pyridoxal derivatives |
| IL62602A (en) * | 1980-05-19 | 1984-06-29 | Labaz Sanofi Nv | Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them |
| US4542026A (en) * | 1983-04-29 | 1985-09-17 | Jose Rios | Method of treating vasomotor disorders |
| US4579846A (en) * | 1984-10-11 | 1986-04-01 | Pfizer Inc. | Antiinflammatory compositions and methods |
| FR2641189B1 (fr) * | 1988-06-20 | 1991-05-10 | Timol Mamoojee | Compositions pharmaceutiques contenant de l'acide acetyl salicylique et de la vitamine b6 |
| US20040180865A1 (en) * | 1993-06-04 | 2004-09-16 | Jeffry W. Kreamer | Aspirin and vitamin and/or trace element compositions for the amelioration and treatment of vascular disease |
-
1998
- 1998-04-16 US US09/061,173 patent/US6051587A/en not_active Expired - Fee Related
-
1999
- 1999-04-16 BR BRPI9909672-2A patent/BR9909672A/pt not_active Application Discontinuation
- 1999-04-16 CA CA002328730A patent/CA2328730C/en not_active Expired - Fee Related
- 1999-04-16 AU AU34029/99A patent/AU765749B2/en not_active Ceased
- 1999-04-16 ES ES99915411T patent/ES2260906T3/es not_active Expired - Lifetime
- 1999-04-16 DE DE69930243T patent/DE69930243T2/de not_active Expired - Fee Related
- 1999-04-16 EP EP99915411A patent/EP1071430B1/en not_active Expired - Lifetime
- 1999-04-16 IL IL13968199A patent/IL139681A0/xx unknown
- 1999-04-16 JP JP2000544332A patent/JP2002512194A/ja not_active Withdrawn
- 1999-04-16 AT AT99915411T patent/ATE319457T1/de not_active IP Right Cessation
- 1999-04-16 WO PCT/CA1999/000331 patent/WO1999053928A1/en not_active Ceased
- 1999-04-16 NZ NZ508142A patent/NZ508142A/xx unknown
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