JP2002511746A5 - - Google Patents

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Publication number
JP2002511746A5
JP2002511746A5 JP1998549413A JP54941398A JP2002511746A5 JP 2002511746 A5 JP2002511746 A5 JP 2002511746A5 JP 1998549413 A JP1998549413 A JP 1998549413A JP 54941398 A JP54941398 A JP 54941398A JP 2002511746 A5 JP2002511746 A5 JP 2002511746A5
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JP
Japan
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JP1998549413A
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JP4050329B2 (ja
JP2002511746A (ja
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Priority claimed from PCT/US1998/009629 external-priority patent/WO1998051803A1/en
Publication of JP2002511746A publication Critical patent/JP2002511746A/ja
Publication of JP2002511746A5 publication Critical patent/JP2002511746A5/ja
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Figure 2002511746
Figure 2002511746
Figure 2002511746
Figure 2002511746
JP54941398A 1997-05-16 1998-05-12 プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸 Expired - Fee Related JP4050329B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US85788497A 1997-05-16 1997-05-16
US08/857,884 1997-05-16
US6289297P 1997-10-20 1997-10-20
US60/062,892 1997-10-20
PCT/US1998/009629 WO1998051803A1 (en) 1997-05-16 1998-05-12 Polypeptides having prolyl pipeptidyl aminopeptidase activity and nucleic acids encoding same

Publications (3)

Publication Number Publication Date
JP2002511746A JP2002511746A (ja) 2002-04-16
JP2002511746A5 true JP2002511746A5 (ja) 2005-12-08
JP4050329B2 JP4050329B2 (ja) 2008-02-20

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JP54941398A Expired - Fee Related JP4050329B2 (ja) 1997-05-16 1998-05-12 プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸

Country Status (9)

Country Link
US (2) US6664092B1 (ja)
EP (1) EP0981630B1 (ja)
JP (1) JP4050329B2 (ja)
CN (1) CN1227363C (ja)
AT (1) ATE414775T1 (ja)
AU (1) AU7381098A (ja)
DE (1) DE69840230D1 (ja)
DK (1) DK0981630T3 (ja)
WO (1) WO1998051803A1 (ja)

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US7186540B2 (en) * 2001-12-27 2007-03-06 National Institute of Advanced Indusrtial Science and Technology Thermostable glutaminase and thermostable glutaminase gene
AU2003236689A1 (en) 2002-06-04 2003-12-19 Dsm Ip Assets B.V. Protein hydrolysate rich in tripeptides
JP4300289B2 (ja) * 2002-08-27 2009-07-22 国立大学法人 岡山大学 加水分解又は脱水縮合酵素、及び当該酵素の生産方法、並びに当該酵素を用いたアミドの合成方法
JP4887139B2 (ja) 2003-03-25 2012-02-29 武田薬品工業株式会社 ジペプチジルペプチダーゼインヒビター
JP2007511467A (ja) 2003-05-14 2007-05-10 タケダ サン ディエゴ インコーポレイテッド ジペプチジルペプチダーゼインヒビター
MXPA06000878A (es) * 2003-08-01 2006-03-30 Calpis Co Ltd Hidrolizado de caseina, proceso para producirla y uso de la misma.
RU2006107553A (ru) 2003-08-13 2007-09-20 Такеда Фармасьютикал Компани Лимитед (Jp) Производные 4-пиримидона и их применение в качестве ингибиторов пептидилпептидаз
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1699777B1 (en) 2003-09-08 2012-12-12 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
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WO2005118555A1 (en) 2004-06-04 2005-12-15 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2006019965A2 (en) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
WO2006068978A2 (en) 2004-12-21 2006-06-29 Takeda Pharmaceutial Company Limited Dipeptidyl peptidase inhibitors
NZ566799A (en) 2005-09-14 2011-04-29 Takeda Pharmaceutical Dipeptidyl peptidase inhibitors for treating diabetes
CN101360723A (zh) 2005-09-16 2009-02-04 武田药品工业株式会社 制备嘧啶二酮衍生物的方法
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
EP2398822B1 (en) * 2009-02-19 2013-01-02 Novo Nordisk A/S Modification of factor viii
JP5759132B2 (ja) * 2010-09-21 2015-08-05 月桂冠株式会社 糸状菌ペプチダーゼの生産方法
WO2013092731A1 (en) * 2011-12-21 2013-06-27 Dsm Ip Assets B.V. Method for making a dough with a glutamyl endopeptidase
CN103695361B (zh) * 2013-12-06 2015-11-11 江南大学 一种生产脯氨酸氨肽酶的基因工程菌及其构建方法

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