JP2002510653A - 緩衝剤としてコハク酸を含有する注射可能なｉｇｆ処方物 - Google Patents

緩衝剤としてコハク酸を含有する注射可能なｉｇｆ処方物

Info

Publication number
JP2002510653A
JP2002510653A JP2000542042A JP2000542042A JP2002510653A JP 2002510653 A JP2002510653 A JP 2002510653A JP 2000542042 A JP2000542042 A JP 2000542042A JP 2000542042 A JP2000542042 A JP 2000542042A JP 2002510653 A JP2002510653 A JP 2002510653A
Authority
JP
Japan
Prior art keywords
igf
pharmaceutically active
injection
composition
active agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000542042A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002510653A5 (enExample
Inventor
ブレット エイ． シャーリー，
マニンダー エス． ホラ，
Original Assignee
カイロン コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by カイロン コーポレイション filed Critical カイロン コーポレイション
Publication of JP2002510653A publication Critical patent/JP2002510653A/ja
Publication of JP2002510653A5 publication Critical patent/JP2002510653A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2000542042A 1998-04-03 1999-04-02 緩衝剤としてコハク酸を含有する注射可能なｉｇｆ処方物 Pending JP2002510653A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8000898P 1998-04-03 1998-04-03
US60/080,008 1998-04-03
PCT/US1999/007531 WO1999051272A1 (en) 1998-04-03 1999-04-02 Injectable igf-formulations containing succinate as buffering agent

Publications (2)

Publication Number Publication Date
JP2002510653A true JP2002510653A (ja) 2002-04-09
JP2002510653A5 JP2002510653A5 (enExample) 2006-05-25

Family

ID=22154445

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000542042A Pending JP2002510653A (ja) 1998-04-03 1999-04-02 緩衝剤としてコハク酸を含有する注射可能なｉｇｆ処方物

Country Status (10)

Country Link
US (1) US20070249522A1 (enExample)
EP (1) EP1069912B1 (enExample)
JP (1) JP2002510653A (enExample)
AT (1) ATE367828T1 (enExample)
AU (1) AU3473999A (enExample)
DE (1) DE69936638T2 (enExample)
DK (1) DK1069912T3 (enExample)
ES (1) ES2288018T3 (enExample)
PT (1) PT1069912E (enExample)
WO (1) WO1999051272A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021506952A (ja) * 2018-06-22 2021-02-22 イーライ リリー アンド カンパニー Ｇｉｐ／ｇｌｐ１アゴニスト組成物
JP2022533971A (ja) * 2019-05-15 2022-07-27 ベクソン バイオメディカル，インク． 皮下注射のためのケタミン製剤

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL149008A0 (en) 1999-10-04 2002-11-10 Chiron Corp Stabilized liquid polypeptide-containing pharmaceutical compositions
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
WO2003018782A2 (en) 2001-08-30 2003-03-06 Stem Cell Therapeutics Inc. Differentiation of neural stem cells and therapeutic use theeof
ATE541921T1 (de) 2001-09-14 2012-02-15 Stem Cell Therapeutics Inc Prolaktin-induzierte zunahme an neuronalen stammzellen und dessen therapeutische anwendung
EP1430113A2 (en) * 2001-09-18 2004-06-23 Stem Cell Therapeutics Inc. Effect of growth hormone and igf-1 on neural stem cells and therapeutic application
CA2492442A1 (en) 2002-07-31 2004-02-05 Stem Cell Therapeutics Inc. Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
JP2006515882A (ja) 2003-01-08 2006-06-08 カイロン コーポレイション 組織因子経路インヒビター（ｔｆｐｉ）または組織因子経路インヒビター改変体を含有する安定化水性組成物
EP1928488A4 (en) 2005-09-27 2009-07-22 Stem Cell Therapeutics Corp REGULATION OF OLIGODENDROCYTE PRECURSOR CELL PROLIFERATION WITH PROLACTIN
US11097023B1 (en) * 2020-07-02 2021-08-24 Par Pharmaceutical, Inc. Pre-filled syringe containing sugammadex

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3273597D1 (en) * 1981-11-28 1986-11-06 Sunstar Kk Pharmaceutical composition containing interferon in stable state
JPS6069037A (ja) * 1983-09-26 1985-04-19 Sunstar Inc エリテマト−デス治療用外用剤
US4605555A (en) * 1984-09-20 1986-08-12 Sun Star Kabushiki Kaisha Composition and method for treating keratosic disorder of skin and mucosa
EP0284249A1 (en) * 1987-03-13 1988-09-28 Interferon Sciences, Inc. Lyophilized lymphokine composition
US5151265A (en) * 1987-11-03 1992-09-29 Genentech, Inc. Gamma interferon formulation
DE68907066T2 (de) * 1988-01-29 1993-12-16 Koken Kk Verbesserte Formulierungen mit kontrollierter Abgabe.
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
US5126324A (en) * 1990-06-07 1992-06-30 Genentech, Inc. Method of enhancing growth in patients using combination therapy
US5374620A (en) * 1990-06-07 1994-12-20 Genentech, Inc. Growth-promoting composition and its use
US5589167A (en) * 1993-02-23 1996-12-31 Genentech, Inc. Excipient stabilization of polypeptides treated with organic solvents
IT1272252B (it) * 1994-05-16 1997-06-16 Applied Research Systems Formulazioni liquide di interferone beta
TW426523B (en) * 1995-04-06 2001-03-21 Hoffmann La Roche Interferon solution
US6511811B1 (en) * 1995-06-07 2003-01-28 The Regents Of The University Of California Protein kinase C antagonist related to insulin receptor
US5977057A (en) * 1996-05-08 1999-11-02 The University Of Vermont And State Agricultural College Thrombosis prophylaxis for factor VLEIDEN carriers
US5783556A (en) * 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition
DE19825736C2 (de) * 1997-06-11 2003-09-18 Hyundai Electronics Ind Verfahren zum Bilden eines Kondensators einer Halbleitervorrichtung
US6663899B2 (en) * 1997-06-13 2003-12-16 Genentech, Inc. Controlled release microencapsulated NGF formulation
US6887462B2 (en) * 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021506952A (ja) * 2018-06-22 2021-02-22 イーライ リリー アンド カンパニー Ｇｉｐ／ｇｌｐ１アゴニスト組成物
JP2021167314A (ja) * 2018-06-22 2021-10-21 イーライ リリー アンド カンパニー Ｇｉｐ／ｇｌｐ１アゴニスト組成物
JP7413315B2 (ja) 2018-06-22 2024-01-15 イーライ リリー アンド カンパニー Ｇｉｐ／ｇｌｐ１アゴニスト組成物
JP2024041808A (ja) * 2018-06-22 2024-03-27 イーライ リリー アンド カンパニー Ｇｉｐ／ｇｌｐ１アゴニスト組成物
JP7700205B2 (ja) 2018-06-22 2025-06-30 イーライ リリー アンド カンパニー Ｇｉｐ／ｇｌｐ１アゴニスト組成物
JP2022533971A (ja) * 2019-05-15 2022-07-27 ベクソン バイオメディカル，インク． 皮下注射のためのケタミン製剤

Also Published As

Publication number Publication date
US20070249522A1 (en) 2007-10-25
WO1999051272A1 (en) 1999-10-14
DK1069912T3 (da) 2007-11-12
AU3473999A (en) 1999-10-25
PT1069912E (pt) 2007-09-14
DE69936638D1 (de) 2007-09-06
EP1069912B1 (en) 2007-07-25
EP1069912A1 (en) 2001-01-24
DE69936638T2 (de) 2008-05-21
ES2288018T3 (es) 2007-12-16
ATE367828T1 (de) 2007-08-15

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