JP2002510463A - 抗菌化合物 - Google Patents

抗菌化合物

Info

Publication number
JP2002510463A
JP2002510463A JP2000528707A JP2000528707A JP2002510463A JP 2002510463 A JP2002510463 A JP 2002510463A JP 2000528707 A JP2000528707 A JP 2000528707A JP 2000528707 A JP2000528707 A JP 2000528707A JP 2002510463 A JP2002510463 A JP 2002510463A
Authority
JP
Japan
Prior art keywords
compound
polypeptide
triclosan
mutant
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2000528707A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002510463A5 (fr
Inventor
スチュアート ビー. レヴィー
ローラ エム. マクマリー
Original Assignee
トルスティーズ オブ トゥフツ カレッジ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by トルスティーズ オブ トゥフツ カレッジ filed Critical トルスティーズ オブ トゥフツ カレッジ
Publication of JP2002510463A publication Critical patent/JP2002510463A/ja
Publication of JP2002510463A5 publication Critical patent/JP2002510463A5/ja
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/001Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2000528707A 1998-01-23 1999-01-22 抗菌化合物 Abandoned JP2002510463A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7224498P 1998-01-23 1998-01-23
US60/072,244 1998-01-23
US1344098A 1998-01-26 1998-01-26
US09/013,440 1998-01-26
PCT/US1999/001288 WO1999037800A1 (fr) 1998-01-23 1999-01-22 Composes antimicrobiens

Publications (2)

Publication Number Publication Date
JP2002510463A true JP2002510463A (ja) 2002-04-09
JP2002510463A5 JP2002510463A5 (fr) 2006-03-09

Family

ID=26684842

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000528707A Abandoned JP2002510463A (ja) 1998-01-23 1999-01-22 抗菌化合物

Country Status (6)

Country Link
EP (1) EP1049799A1 (fr)
JP (1) JP2002510463A (fr)
AU (1) AU2332499A (fr)
CA (1) CA2319115A1 (fr)
IL (1) IL137444A0 (fr)
WO (1) WO1999037800A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007091395A1 (fr) * 2006-02-10 2007-08-16 Tokai University Procédé ou agent pour inhiber la fonction de pompe à éjection de pseudomonas aeruginosa

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6713043B2 (en) 1996-02-29 2004-03-30 The Trustees Of Columbia University In The City Of New York Antimicrobial activity of gemfibrozil
US6346391B1 (en) 1999-07-22 2002-02-12 Trustees Of Tufts College Methods of reducing microbial resistance to drugs
US6951729B1 (en) * 1999-10-27 2005-10-04 Affinium Pharmaceuticals, Inc. High throughput screening method for biological agents affecting fatty acid biosynthesis
US6531291B1 (en) 1999-11-10 2003-03-11 The Trustees Of Columbia University In The City Of New York Antimicrobial activity of gemfibrozil and related compounds and derivatives and metabolites thereof
GB2509159B (en) 2012-12-21 2017-07-26 Oxoid Ltd Triclosan derivatives and uses thereof
PT3297666T (pt) 2015-05-22 2019-09-06 Consejo Superior Investigacion Adjuvante e vacina molecular

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5702935A (en) * 1994-04-28 1997-12-30 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Method and compounds for inhibiting lipid biosynthesis of bacteria and plants
BR9603085A (pt) * 1996-07-12 1998-05-05 Cosmeticos Natural Ind Com Sabonete antisséptico líquido para cuidado da pele
DE69735225T2 (de) * 1996-08-28 2006-11-02 Affinium Pharmaceuticals, Inc., Toronto Fab I Enoyl-ACP-Reduktase aus Staphylokokken

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007091395A1 (fr) * 2006-02-10 2007-08-16 Tokai University Procédé ou agent pour inhiber la fonction de pompe à éjection de pseudomonas aeruginosa
US7985410B2 (en) 2006-02-10 2011-07-26 Tokai University Method or agent for inhibiting the function of efflux pump Pseudomonas aeruginosa
AU2007213275B2 (en) * 2006-02-10 2013-01-10 Tokai University Method or agent for inhibiting the function of efflux pump of Pseudomonas aeruginosa
JP5314286B2 (ja) * 2006-02-10 2013-10-16 学校法人東海大学 緑膿菌の薬剤排出ポンプの機能を阻害する方法及び薬剤

Also Published As

Publication number Publication date
WO1999037800A1 (fr) 1999-07-29
IL137444A0 (en) 2001-07-24
AU2332499A (en) 1999-08-09
CA2319115A1 (fr) 1999-07-29
EP1049799A1 (fr) 2000-11-08

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