JP2002506425A - ポリヌクレオチド分離のための改良された液体クロマトグラフィー媒体 - Google Patents

ポリヌクレオチド分離のための改良された液体クロマトグラフィー媒体

Info

Publication number
JP2002506425A
JP2002506425A JP54717998A JP54717998A JP2002506425A JP 2002506425 A JP2002506425 A JP 2002506425A JP 54717998 A JP54717998 A JP 54717998A JP 54717998 A JP54717998 A JP 54717998A JP 2002506425 A JP2002506425 A JP 2002506425A
Authority
JP
Japan
Prior art keywords
beads
bead
silica
separation
porous particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP54717998A
Other languages
English (en)
Japanese (ja)
Inventor
グジエルド，ダグラス・テイ
テイラー，ポール・デイ
Original Assignee
トランスジエノミツク・インコーポレーテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by トランスジエノミツク・インコーポレーテツド filed Critical トランスジエノミツク・インコーポレーテツド
Publication of JP2002506425A publication Critical patent/JP2002506425A/ja
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287—Non-polar phases; Reversed phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3225—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating involving a post-treatment of the coated or impregnated product
    • B01J20/3227—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating involving a post-treatment of the coated or impregnated product by end-capping, i.e. with or after the introduction of functional or ligand groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP54717998A 1997-04-25 1998-04-24 ポリヌクレオチド分離のための改良された液体クロマトグラフィー媒体 Pending JP2002506425A (ja)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US4485697P 1997-04-25 1997-04-25
US60/044,856 1997-04-25
US5545697P 1997-08-11 1997-08-11
US60/055,456 1997-08-11
US5952797P 1997-09-22 1997-09-22
US60/059,527 1997-09-22
US6212397P 1997-10-15 1997-10-15
US60/062,123 1997-10-15
US6230397P 1997-10-17 1997-10-17
US60/062,303 1997-10-17
US6361997P 1997-10-27 1997-10-27
US60/063,619 1997-10-27
US6931397P 1997-12-05 1997-12-05
US60/069,313 1997-12-05
US7799898P 1998-03-13 1998-03-13
US60/077,998 1998-03-13
US5833798A 1998-04-10 1998-04-10
US09/058,337 1998-04-10
PCT/US1998/008293 WO1998048914A1 (fr) 1997-04-25 1998-04-24 Milieu chromatographique liquide ameliore utilise dans la separation de polynucleotides

Publications (1)

Publication Number Publication Date
JP2002506425A true JP2002506425A (ja) 2002-02-26

Family

ID=27578183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54717998A Pending JP2002506425A (ja) 1997-04-25 1998-04-24 ポリヌクレオチド分離のための改良された液体クロマトグラフィー媒体

Country Status (5)

Country Link
EP (1) EP1027121A4 (fr)
JP (1) JP2002506425A (fr)
AU (1) AU725928B2 (fr)
CA (1) CA2285307A1 (fr)
WO (1) WO1998048914A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002337100A (ja) * 2001-03-13 2002-11-26 Inst Of Physical & Chemical Res ナノ被覆分子性材料
WO2012033194A1 (fr) * 2010-09-09 2012-03-15 ダイセル化学工業株式会社 Procédé servant à séparer un matériau biologique soluble dans l'eau
WO2017115655A1 (fr) * 2015-12-28 2017-07-06 昭和電工株式会社 Procédé de séparation et analyse

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6475388B1 (en) 1996-11-13 2002-11-05 Transgenomic, Inc. Method and system for RNA analysis by matched ion polynucleotide chromatography
US6576133B2 (en) 1996-11-13 2003-06-10 Transgenomic, Inc Method and system for RNA analysis by matched ion polynucleotide chromatography
US6177559B1 (en) 1998-04-24 2001-01-23 Transgenomic, Inc. Process for separation of polynucleotide fragments
JP2001521729A (ja) * 1997-10-30 2001-11-13 トランスジエノミツク・インコーポレーテツド ポリヌクレオチドの高分離の液体クロマトグラフィー分離方法
US6258264B1 (en) 1998-04-10 2001-07-10 Transgenomic, Inc. Non-polar media for polynucleotide separations
US6265168B1 (en) 1998-10-06 2001-07-24 Transgenomic, Inc. Apparatus and method for separating and purifying polynucleotides
AU777251B2 (en) * 2000-05-01 2004-10-07 Transgenomic, Inc. Polynucleotide separations on polymeric separation media
CA2396667A1 (fr) * 2000-05-26 2001-12-06 Benjamin L. Legendre, Jr. Appareil et procede permettant la separation et la purification de polynucleotides
US6521411B2 (en) 2000-09-28 2003-02-18 Transgenomic, Inc. Method and system for the preparation of cDNA
DE10120821A1 (de) * 2001-04-27 2002-10-31 Sachtleben Chemie Gmbh Mit Polyalken beschichtete, poröse Füllstoffe
AU2002334892A1 (en) 2001-10-05 2003-04-22 Transgenomic, Inc. Methods and compositions for mutation analysis by liquid chromatography
EP2570183A1 (fr) * 2011-09-15 2013-03-20 InstrAction GmbH Sorbant comportant à sa surface une unité aliphatique pour la purification des molécules organiques
MX2018013486A (es) * 2016-05-06 2019-03-28 Goldcorp Inc Composicion adsorbente, metodo de elaboracion de la misma y usos del mismo.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6281400A (ja) * 1985-10-04 1987-04-14 Toyo Soda Mfg Co Ltd 核酸の分離方法
JPH08505700A (ja) * 1992-11-18 1996-06-18 サラセプ インコーポレイテッド 核酸断片の分離法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042327A (en) * 1976-01-15 1977-08-16 Waters Associates, Inc. Ion-pairing chromatography
US5015373A (en) * 1988-02-03 1991-05-14 Regents Of The University Of Minnesota High stability porous zirconium oxide spherules
CA2102425A1 (fr) * 1991-03-04 1992-09-05 Ethan S. Simon Revetement a base de polymere de butadieneacrylonitrile et materiel de garnissage de colonne de chromatographie
US5100547A (en) * 1991-03-04 1992-03-31 Monsanto Company Chromatography supports consisting of an inorganic susbstrate coated with polybutadiene with alkyl side chains
US5772889A (en) * 1995-11-13 1998-06-30 Transgenomic, Inc. System and method for performing nucleic acid separations using liquid chromatography

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6281400A (ja) * 1985-10-04 1987-04-14 Toyo Soda Mfg Co Ltd 核酸の分離方法
JPH08505700A (ja) * 1992-11-18 1996-06-18 サラセプ インコーポレイテッド 核酸断片の分離法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002337100A (ja) * 2001-03-13 2002-11-26 Inst Of Physical & Chemical Res ナノ被覆分子性材料
WO2012033194A1 (fr) * 2010-09-09 2012-03-15 ダイセル化学工業株式会社 Procédé servant à séparer un matériau biologique soluble dans l'eau
JP5926682B2 (ja) * 2010-09-09 2016-05-25 株式会社ダイセル 水溶性生体関連物質の分離方法
WO2017115655A1 (fr) * 2015-12-28 2017-07-06 昭和電工株式会社 Procédé de séparation et analyse

Also Published As

Publication number Publication date
WO1998048914A1 (fr) 1998-11-05
AU7157798A (en) 1998-11-24
EP1027121A4 (fr) 2001-07-11
AU725928B2 (en) 2000-10-26
CA2285307A1 (fr) 1998-11-05
EP1027121A1 (fr) 2000-08-16

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