JP2002503674A5 - - Google Patents
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- Publication number
- JP2002503674A5 JP2002503674A5 JP2000531467A JP2000531467A JP2002503674A5 JP 2002503674 A5 JP2002503674 A5 JP 2002503674A5 JP 2000531467 A JP2000531467 A JP 2000531467A JP 2000531467 A JP2000531467 A JP 2000531467A JP 2002503674 A5 JP2002503674 A5 JP 2002503674A5
- Authority
- JP
- Japan
- Prior art keywords
- chemical
- compound according
- nrr
- ring
- nhr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1998/002891 WO1999041276A1 (en) | 1998-02-12 | 1998-02-12 | β-SHEET MIMETICS AND METHODS RELATING TO THE USE THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002503674A JP2002503674A (ja) | 2002-02-05 |
| JP2002503674A5 true JP2002503674A5 (enExample) | 2005-12-22 |
Family
ID=22266392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000531467A Pending JP2002503674A (ja) | 1998-02-12 | 1998-02-12 | βシート模倣物およびその使用に関する方法 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1053246B1 (enExample) |
| JP (1) | JP2002503674A (enExample) |
| KR (1) | KR20010040939A (enExample) |
| AT (1) | ATE230414T1 (enExample) |
| AU (1) | AU748887B2 (enExample) |
| CA (1) | CA2319766A1 (enExample) |
| DE (1) | DE69810513T2 (enExample) |
| ES (1) | ES2192764T3 (enExample) |
| WO (1) | WO1999041276A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1261611A2 (en) * | 2000-02-29 | 2002-12-04 | Bristol-Myers Squibb Pharma Company | Inhibitors of hepatitis c virus ns3 protease |
| US6534651B2 (en) | 2000-04-06 | 2003-03-18 | Inotek Pharmaceuticals Corp. | 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof |
| US20060276497A1 (en) | 2000-05-09 | 2006-12-07 | Cephalon, Inc. | Novel multicyclic compounds and the use thereof |
| US7122679B2 (en) | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
| JP2005526722A (ja) * | 2002-02-14 | 2005-09-08 | ミリアド・ジェネティックス・インコーポレイテッド | β−シートミメティックならびにそれに関連する組成物および方法 |
| US20110212078A1 (en) | 2008-06-25 | 2011-09-01 | Reddy Panduranga Adulla P | Synthesis and use of heterocyclic antibacterial agents |
| SG11201702797RA (en) | 2014-10-06 | 2017-05-30 | Cortexyme Inc | Inhibitors of lysine gingipain |
| CA3004095A1 (en) | 2015-11-09 | 2017-05-18 | Cortexyme, Inc. | Inhibitors of arginine gingipain |
| HUE057289T2 (hu) | 2016-08-31 | 2022-05-28 | Jiangsu Hengrui Medicine Co | Oxopikolinamid-származék, annak elõállítási módszere és gyógyszerészeti felhasználása |
| MX2019003087A (es) | 2016-09-16 | 2019-08-12 | Cortexyme Inc | Inhibidores cetónicos de gingipain de lisina. |
| CN112004810B (zh) | 2018-07-02 | 2022-04-08 | 江苏恒瑞医药股份有限公司 | 一种氧代吡啶酰胺类衍生物的晶型及制备方法 |
| MX2022003649A (es) | 2019-09-27 | 2022-06-08 | Shenzhen Salubris Pharm Co Ltd | Inhibidores del fxia y metodo de preparacion de los mismos y uso farmaceutico de los mismos. |
| CN119894901A (zh) | 2023-06-30 | 2025-04-25 | 深圳信立泰药业股份有限公司 | 一种多取代的大环化合物及其制备方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993016103A1 (en) * | 1992-02-14 | 1993-08-19 | Merrell Dow Pharmaceuticals Inc. | Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
| AU669364B2 (en) * | 1992-05-15 | 1996-06-06 | Merrell Pharmaceuticals Inc. | Novel mercaptoacetylamido pyridazo(1,2)pyridazine, pyrazolo(1,2)pyridazine, pyridazo(1,2-a)(1,2)diazepine and pyrazolo(1,2-a)(1,2)diazepine derivatives useful as inhibitors of enkephalinase and ace |
| EP0618223A3 (en) * | 1993-03-08 | 1996-06-12 | Sandoz Ltd | Peptides, the release of Interleukin 1-Bêta, useful as anti-inflammatory agents. |
| NZ297360A (en) * | 1994-12-22 | 2000-03-27 | Iaf Biochem Int | 5-oxo-5H-thiazolo[3,2-a]pyridine, 5-oxo-2-thia-4a,7-diaza-naphthalene, 4-oxo-octahydro-pyrrolo[1,2-a]pyrazine or 6-oxo-octahydro-pyrido-[2,1-c][1,4]thiazine derivatives and medicaments |
| EP0817642A1 (en) * | 1995-03-24 | 1998-01-14 | Molecumetics, Ltd. | $g(b)-SHEET MIMETICS AND USE THEREOF AS INHIBITORS OF BIOLOGICALLY ACTIVE PEPTIDES OR PROTEINS |
| WO1996030396A1 (en) * | 1995-03-24 | 1996-10-03 | Molecumetics Ltd. | β-SHEET MIMETICS AND USE THEREOF AS PROTEASE INHIBITORS |
| US5877313A (en) * | 1995-05-17 | 1999-03-02 | Bristol-Myers Squibb | Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP |
| IT1277405B1 (it) * | 1995-08-01 | 1997-11-10 | Menarini Farma Ind | Derivati di lattami biciclici come inibitori della trombina |
| NZ334227A (en) * | 1996-08-05 | 2000-10-27 | Molecumetics Ltd | Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors |
-
1998
- 1998-02-12 CA CA002319766A patent/CA2319766A1/en not_active Abandoned
- 1998-02-12 DE DE69810513T patent/DE69810513T2/de not_active Expired - Lifetime
- 1998-02-12 AU AU66557/98A patent/AU748887B2/en not_active Ceased
- 1998-02-12 AT AT98908551T patent/ATE230414T1/de not_active IP Right Cessation
- 1998-02-12 JP JP2000531467A patent/JP2002503674A/ja active Pending
- 1998-02-12 ES ES98908551T patent/ES2192764T3/es not_active Expired - Lifetime
- 1998-02-12 EP EP98908551A patent/EP1053246B1/en not_active Expired - Lifetime
- 1998-02-12 WO PCT/US1998/002891 patent/WO1999041276A1/en not_active Ceased
- 1998-02-12 KR KR1020007008856A patent/KR20010040939A/ko not_active Ceased
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