JP2002501534A5 - - Google Patents
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- Publication number
- JP2002501534A5 JP2002501534A5 JP1999500802A JP50080299A JP2002501534A5 JP 2002501534 A5 JP2002501534 A5 JP 2002501534A5 JP 1999500802 A JP1999500802 A JP 1999500802A JP 50080299 A JP50080299 A JP 50080299A JP 2002501534 A5 JP2002501534 A5 JP 2002501534A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/865,666 US6096881A (en) | 1997-05-30 | 1997-05-30 | Sulfur transfer reagents for oligonucleotide synthesis |
| US08/865,666 | 1997-05-30 | ||
| PCT/US1998/010653 WO1998054198A1 (en) | 1997-05-30 | 1998-05-26 | Novel sulfur transfer reagents for oligonucleotide synthesis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002501534A JP2002501534A (ja) | 2002-01-15 |
| JP2002501534A5 true JP2002501534A5 (enExample) | 2005-12-08 |
| JP4393594B2 JP4393594B2 (ja) | 2010-01-06 |
Family
ID=25345990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50080299A Expired - Lifetime JP4393594B2 (ja) | 1997-05-30 | 1998-05-26 | オリゴヌクレオチド合成用新規硫黄転移試薬 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6096881A (enExample) |
| EP (1) | EP0986571B1 (enExample) |
| JP (1) | JP4393594B2 (enExample) |
| AT (1) | ATE271065T1 (enExample) |
| AU (1) | AU7597498A (enExample) |
| CA (1) | CA2291688C (enExample) |
| DE (1) | DE69825051T2 (enExample) |
| ES (1) | ES2226135T3 (enExample) |
| WO (1) | WO1998054198A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7098325B2 (en) * | 1998-10-08 | 2006-08-29 | Pierre Martin | Process for the sulfurization of a phosphorus-containing compound |
| DE69910140T2 (de) * | 1998-10-08 | 2004-06-03 | Novartis Ag | Verfahren zur Sulfurierung von Phosphor-enthaltenden Verbindungen |
| GB0004889D0 (en) | 2000-03-01 | 2000-04-19 | Avecia Ltd | Synthesis of oligonucleotides |
| EP1343802B1 (en) * | 2000-12-05 | 2012-05-30 | Avecia Biotechnology Inc | Process for the preparation of oligonucleotides |
| US6768005B2 (en) * | 2000-12-20 | 2004-07-27 | Avecia Limited | Process |
| AR036122A1 (es) * | 2001-07-03 | 2004-08-11 | Avecia Biotechnology Inc | Un complejo de sal que comprende un n-alquilimidazol y una 1,1-dioxo-1,2-dihidro-1l6-benzo [d]-isotiazol-3-ona y un metodo para sintetizar oligonucleotidos utilizando la quimica de fosforamidita |
| JP4825375B2 (ja) * | 2001-08-28 | 2011-11-30 | 株式会社 資生堂 | ジチアゾール化合物及びマトリックスメタロプロテアーゼ活性阻害剤、皮膚外用剤 |
| GB0209539D0 (en) * | 2002-04-26 | 2002-06-05 | Avecia Ltd | Monomer Polymer and process |
| CA2561741C (en) * | 2004-04-05 | 2016-09-27 | Alnylam Pharmaceuticals, Inc. | Processes and reagents for oligonucleotide synthesis and purification |
| CN104086516B (zh) * | 2014-07-18 | 2016-01-06 | 成都樵枫科技发展有限公司 | R-(+)-硫代四氢呋喃-2-甲酸的合成方法 |
| KR20190100225A (ko) | 2016-12-28 | 2019-08-28 | 다이이찌 산쿄 가부시키가이샤 | 알포트 증후군 치료약 |
| WO2019111791A1 (ja) * | 2017-12-07 | 2019-06-13 | 第一三共株式会社 | ジストロフィン遺伝子のイントロンリテンションを解消するアンチセンスオリゴヌクレオチド |
| CN115976028B (zh) | 2018-03-09 | 2025-03-25 | 第一三共株式会社 | 糖原病Ia型治疗药 |
| US20210207136A1 (en) | 2018-06-13 | 2021-07-08 | Daiichi Sankyo Company, Limited | Myocardial dysfunction therapeutic agent |
| WO2020246560A1 (ja) | 2019-06-05 | 2020-12-10 | 学校法人福岡大学 | 化学修飾核酸を導入した安定型標的編集ガイドｒｎａ |
| JP7715345B2 (ja) | 2019-06-26 | 2025-07-30 | 神戸天然物化学株式会社 | ミオスタチン遺伝子のｍＲＮＡの産生を抑制する核酸医薬 |
| US20220364086A1 (en) | 2019-07-12 | 2022-11-17 | Daiichi Sankyo Company, Limited | ANTISENSE OLIGONUCLEOTIDE CAPABLE OF ALTERING SPLICING OF DUX4 pre-mRNA |
| CA3150715A1 (en) | 2019-09-10 | 2021-03-18 | Makoto Koizumi | Conjugate of galnac-oligonucleotide for delivery to liver and manufacturing method thereof |
| TW202128704A (zh) | 2019-10-18 | 2021-08-01 | 日商第一三共股份有限公司 | 雙環亞磷醯胺之製造方法 |
| EP4119167A4 (en) | 2020-03-11 | 2025-08-06 | Biocomber Co Ltd | SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR INDUCING FRAME SHIFT-1 AND COMPOSITION |
| US20230272403A1 (en) | 2020-07-28 | 2023-08-31 | Knc Laboratories Co., Ltd. | Antisense oligonucleotide inducing exon skipping of angiotensin converting enzyme 2 gene |
| WO2022124345A1 (ja) | 2020-12-08 | 2022-06-16 | 学校法人福岡大学 | 化学修飾核酸を導入した安定型標的編集ガイドｒｎａ |
| CA3211057A1 (en) | 2021-02-26 | 2022-09-01 | Knc Laboratories Co., Ltd. | Nucleic acid medicine expressing splicing variant of myostatin |
| CN118891366A (zh) | 2022-03-16 | 2024-11-01 | 第一三共株式会社 | 抑制转铁蛋白受体2的表达的siRNA |
| CN118871585A (zh) | 2022-03-16 | 2024-10-29 | 第一三共株式会社 | 具有RNAi活性的化学-修饰的寡核苷酸 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3753908A (en) * | 1971-08-30 | 1973-08-21 | Chevron Res | Oxidation inhibited lubricating oil compositions with extreme pressure properties |
| DE4320157A1 (de) * | 1993-06-18 | 1994-12-22 | Bayer Ag | Verwendung von 1,2,4-Dithiazolium-Salzen als Chemotherapeutica |
-
1997
- 1997-05-30 US US08/865,666 patent/US6096881A/en not_active Expired - Lifetime
-
1998
- 1998-05-26 AT AT98923757T patent/ATE271065T1/de not_active IP Right Cessation
- 1998-05-26 EP EP98923757A patent/EP0986571B1/en not_active Expired - Lifetime
- 1998-05-26 DE DE69825051T patent/DE69825051T2/de not_active Expired - Lifetime
- 1998-05-26 JP JP50080299A patent/JP4393594B2/ja not_active Expired - Lifetime
- 1998-05-26 AU AU75974/98A patent/AU7597498A/en not_active Abandoned
- 1998-05-26 ES ES98923757T patent/ES2226135T3/es not_active Expired - Lifetime
- 1998-05-26 CA CA002291688A patent/CA2291688C/en not_active Expired - Lifetime
- 1998-05-26 WO PCT/US1998/010653 patent/WO1998054198A1/en not_active Ceased