ATE271065T1 - Schwefel-überführungs-reagenz für oligonukleotid- synthese - Google Patents

Schwefel-überführungs-reagenz für oligonukleotid- synthese

Info

Publication number
ATE271065T1
ATE271065T1 AT98923757T AT98923757T ATE271065T1 AT E271065 T1 ATE271065 T1 AT E271065T1 AT 98923757 T AT98923757 T AT 98923757T AT 98923757 T AT98923757 T AT 98923757T AT E271065 T1 ATE271065 T1 AT E271065T1
Authority
AT
Austria
Prior art keywords
sulfur
compounds
reagents
transfer
transfer reagents
Prior art date
Application number
AT98923757T
Other languages
English (en)
Inventor
Han Yongxin
Jimmy Tang
Zhoada Zhang
Jin-Yan Tang
Original Assignee
Avecia Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Biotechnology Inc filed Critical Avecia Biotechnology Inc
Application granted granted Critical
Publication of ATE271065T1 publication Critical patent/ATE271065T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT98923757T 1997-05-30 1998-05-26 Schwefel-überführungs-reagenz für oligonukleotid- synthese ATE271065T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/865,666 US6096881A (en) 1997-05-30 1997-05-30 Sulfur transfer reagents for oligonucleotide synthesis
PCT/US1998/010653 WO1998054198A1 (en) 1997-05-30 1998-05-26 Novel sulfur transfer reagents for oligonucleotide synthesis

Publications (1)

Publication Number Publication Date
ATE271065T1 true ATE271065T1 (de) 2004-07-15

Family

ID=25345990

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98923757T ATE271065T1 (de) 1997-05-30 1998-05-26 Schwefel-überführungs-reagenz für oligonukleotid- synthese

Country Status (9)

Country Link
US (1) US6096881A (de)
EP (1) EP0986571B1 (de)
JP (1) JP4393594B2 (de)
AT (1) ATE271065T1 (de)
AU (1) AU7597498A (de)
CA (1) CA2291688C (de)
DE (1) DE69825051T2 (de)
ES (1) ES2226135T3 (de)
WO (1) WO1998054198A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7098325B2 (en) * 1998-10-08 2006-08-29 Pierre Martin Process for the sulfurization of a phosphorus-containing compound
ATE246693T1 (de) * 1998-10-08 2003-08-15 Novartis Pharma Gmbh Verfahren zur sulfurierung von phosphor- enthaltenden verbindungen
GB0004889D0 (en) 2000-03-01 2000-04-19 Avecia Ltd Synthesis of oligonucleotides
US6768005B2 (en) * 2000-12-20 2004-07-27 Avecia Limited Process
JP2004517089A (ja) * 2000-12-05 2004-06-10 アベシア・リミテッド ホスホロチオエートオリゴヌクレオチドの調製方法
AR036122A1 (es) * 2001-07-03 2004-08-11 Avecia Biotechnology Inc Un complejo de sal que comprende un n-alquilimidazol y una 1,1-dioxo-1,2-dihidro-1l6-benzo [d]-isotiazol-3-ona y un metodo para sintetizar oligonucleotidos utilizando la quimica de fosforamidita
JP4825375B2 (ja) * 2001-08-28 2011-11-30 株式会社 資生堂 ジチアゾール化合物及びマトリックスメタロプロテアーゼ活性阻害剤、皮膚外用剤
GB0209539D0 (en) * 2002-04-26 2002-06-05 Avecia Ltd Monomer Polymer and process
US20050267300A1 (en) * 2004-04-05 2005-12-01 Muthiah Manoharan Processes and reagents for oligonucleotide synthesis and purification
CN104086516B (zh) * 2014-07-18 2016-01-06 成都樵枫科技发展有限公司 R-(+)-硫代四氢呋喃-2-甲酸的合成方法
EP3564373A4 (de) 2016-12-28 2020-12-16 Daiichi Sankyo Company, Limited Therapeutisches arzneimittel gegen das alport-syndrom
WO2019111791A1 (ja) * 2017-12-07 2019-06-13 第一三共株式会社 ジストロフィン遺伝子のイントロンリテンションを解消するアンチセンスオリゴヌクレオチド
JP6884268B2 (ja) 2018-03-09 2021-06-09 第一三共株式会社 糖原病Ｉａ型治療薬
BR112020023503A2 (pt) 2018-06-13 2021-03-30 Daiichi Sankyo Company, Limited Agente terapêutico contra disfunção do miocárdio
WO2020246560A1 (ja) 2019-06-05 2020-12-10 学校法人福岡大学 化学修飾核酸を導入した安定型標的編集ガイドｒｎａ
EP3995153A4 (de) 2019-06-26 2023-11-22 KNC Laboratories Co., Ltd. Nukleinsäurearzneimittel zur unterdrückung der produktion von myostatin-mrna
AU2020313255A1 (en) 2019-07-12 2022-01-06 Daiichi Sankyo Company, Limited Antisense oligonucleotide capable of altering splicing of DUX4 pre-mRNA
WO2021049504A1 (ja) 2019-09-10 2021-03-18 第一三共株式会社 肝臓送達用ＧａｌＮＡｃ－オリゴヌクレオチドコンジュゲートおよび製造方法
IL292286A (en) 2019-10-18 2022-06-01 Daiichi Sankyo Co Ltd Production method for bicyclic phosphoramidite
EP4119167A1 (de) 2020-03-11 2023-01-18 BioComber Co. Ltd Einsträngiges nukleinsäuremolekül zur induzierung von 1-rahmenverschiebung und zusammensetzung
JPWO2022024833A1 (de) 2020-07-28 2022-02-03
CA3201553A1 (en) 2020-12-08 2022-06-16 Fukuoka University Stable target-editing guide rna to which chemically modified nucleic acid is introduced
WO2022181532A1 (ja) 2021-02-26 2022-09-01 学校法人神戸学院 ミオスタチンのスプライシングバリアントを発現させる核酸医薬

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753908A (en) * 1971-08-30 1973-08-21 Chevron Res Oxidation inhibited lubricating oil compositions with extreme pressure properties
DE4320157A1 (de) * 1993-06-18 1994-12-22 Bayer Ag Verwendung von 1,2,4-Dithiazolium-Salzen als Chemotherapeutica

Also Published As

Publication number Publication date
WO1998054198A1 (en) 1998-12-03
US6096881A (en) 2000-08-01
WO1998054198A9 (en) 1999-04-01
JP2002501534A (ja) 2002-01-15
CA2291688A1 (en) 1998-12-03
JP4393594B2 (ja) 2010-01-06
DE69825051T2 (de) 2005-10-06
CA2291688C (en) 2008-01-29
EP0986571B1 (de) 2004-07-14
AU7597498A (en) 1998-12-30
DE69825051D1 (de) 2004-08-19
EP0986571A1 (de) 2000-03-22
ES2226135T3 (es) 2005-03-16

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