JP2002220391A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002220391A5 JP2002220391A5 JP2001357400A JP2001357400A JP2002220391A5 JP 2002220391 A5 JP2002220391 A5 JP 2002220391A5 JP 2001357400 A JP2001357400 A JP 2001357400A JP 2001357400 A JP2001357400 A JP 2001357400A JP 2002220391 A5 JP2002220391 A5 JP 2002220391A5
- Authority
- JP
- Japan
- Prior art keywords
- carbons
- alkyl
- carbon atoms
- hydrogen
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000004432 carbon atom Chemical group C* 0.000 claims 17
- 239000001257 hydrogen Substances 0.000 claims 11
- 229910052739 hydrogen Inorganic materials 0.000 claims 11
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 11
- 125000000217 alkyl group Chemical group 0.000 claims 10
- 150000003839 salts Chemical class 0.000 claims 10
- 150000002475 indoles Chemical class 0.000 claims 9
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 8
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 3
- 125000003342 alkenyl group Chemical group 0.000 claims 3
- 125000003710 aryl alkyl group Chemical group 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 3
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 3
- DMEGYFMYUHOHGS-UHFFFAOYSA-N heptamethylene Natural products C1CCCCCC1 DMEGYFMYUHOHGS-UHFFFAOYSA-N 0.000 claims 3
- 125000004043 oxo group Chemical group O=* 0.000 claims 3
- 125000004430 oxygen atom Chemical group O* 0.000 claims 3
- -1 trifluoro Methoxy, cyano, phenyl Chemical group 0.000 claims 3
- RGSFGYAAUTVSQA-UHFFFAOYSA-N Cyclopentane Chemical compound C1CCCC1 RGSFGYAAUTVSQA-UHFFFAOYSA-N 0.000 claims 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims 2
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 claims 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 1
- 125000001810 isothiocyanato group Chemical group *N=C=S 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001357400A JP4292738B2 (ja) | 2000-11-22 | 2001-11-22 | インドール誘導体およびその医薬用途 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000356382 | 2000-11-22 | ||
| JP2000-356382 | 2000-11-22 | ||
| JP2001357400A JP4292738B2 (ja) | 2000-11-22 | 2001-11-22 | インドール誘導体およびその医薬用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002220391A JP2002220391A (ja) | 2002-08-09 |
| JP2002220391A5 true JP2002220391A5 (https=) | 2005-06-30 |
| JP4292738B2 JP4292738B2 (ja) | 2009-07-08 |
Family
ID=18828643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001357400A Expired - Fee Related JP4292738B2 (ja) | 2000-11-22 | 2001-11-22 | インドール誘導体およびその医薬用途 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6770654B2 (https=) |
| EP (1) | EP1342723B1 (https=) |
| JP (1) | JP4292738B2 (https=) |
| KR (1) | KR20030053530A (https=) |
| CN (1) | CN1247591C (https=) |
| AT (1) | ATE402179T1 (https=) |
| AU (2) | AU2408602A (https=) |
| CA (1) | CA2427931A1 (https=) |
| DE (1) | DE60135016D1 (https=) |
| ES (1) | ES2311034T3 (https=) |
| WO (1) | WO2002042309A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1424337A1 (en) * | 2002-11-26 | 2004-06-02 | Solvay Pharmaceuticals GmbH | 4-hydroxy derivatives of 5,6,9,10-tetrahydro-10-((2-methyl-1h-imidazol-1-yl)methyl)-4h-pyrido-(3,2,1-jk)-carbazol-11(8h)-one |
| EP1602374A4 (en) * | 2003-03-07 | 2007-03-07 | Toray Industries | MEANS FOR TREATMENT OF MEDICAMENT / SUBSTANCE DEPENDENCE |
| CA2580694A1 (en) * | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| WO2006126529A1 (ja) | 2005-05-25 | 2006-11-30 | Shionogi & Co., Ltd. | ６，７－不飽和－７－カルバモイル置換モルヒナン誘導体 |
| JPWO2008001859A1 (ja) * | 2006-06-30 | 2009-11-26 | 学校法人北里研究所 | オピオイドδ受容体アゴニスト |
| EP2149370A1 (en) | 2008-07-31 | 2010-02-03 | Neuroscienze Pharmaness S.C. A R.L. | Diazabicyclic compounds and microemulsions thereof |
| IT1390848B1 (it) | 2008-07-31 | 2011-10-19 | Neuroscienze Pharmaness S C A R L | Composti farmaceutici |
| IT1396951B1 (it) | 2009-12-18 | 2012-12-20 | Neuroscienze Pharmaness S C A R L | Composti farmaceutici |
| US20210015813A1 (en) | 2018-03-08 | 2021-01-21 | Victoria Link Ltd. | Treatment of demyelinating diseases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849731A (en) * | 1995-09-26 | 1998-12-15 | Toray Industries, Inc. | Indole derivatives and medical application thereof |
-
2001
- 2001-11-22 AU AU2408602A patent/AU2408602A/xx active Pending
- 2001-11-22 WO PCT/JP2001/010249 patent/WO2002042309A1/ja not_active Ceased
- 2001-11-22 ES ES01997196T patent/ES2311034T3/es not_active Expired - Lifetime
- 2001-11-22 CA CA002427931A patent/CA2427931A1/en not_active Abandoned
- 2001-11-22 AU AU2002224086A patent/AU2002224086B8/en not_active Ceased
- 2001-11-22 AT AT01997196T patent/ATE402179T1/de not_active IP Right Cessation
- 2001-11-22 CN CNB018221122A patent/CN1247591C/zh not_active Expired - Fee Related
- 2001-11-22 KR KR10-2003-7006870A patent/KR20030053530A/ko not_active Ceased
- 2001-11-22 EP EP01997196A patent/EP1342723B1/en not_active Expired - Lifetime
- 2001-11-22 DE DE60135016T patent/DE60135016D1/de not_active Expired - Fee Related
- 2001-11-22 JP JP2001357400A patent/JP4292738B2/ja not_active Expired - Fee Related
- 2001-11-22 US US10/432,011 patent/US6770654B2/en not_active Expired - Fee Related