JP2001526398A - 質量分析法により液体中の反応速度を決定するための方法及び装置 - Google Patents
質量分析法により液体中の反応速度を決定するための方法及び装置Info
- Publication number
- JP2001526398A JP2001526398A JP2000524808A JP2000524808A JP2001526398A JP 2001526398 A JP2001526398 A JP 2001526398A JP 2000524808 A JP2000524808 A JP 2000524808A JP 2000524808 A JP2000524808 A JP 2000524808A JP 2001526398 A JP2001526398 A JP 2001526398A
- Authority
- JP
- Japan
- Prior art keywords
- reactants
- reaction
- source
- capillary
- volume
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 230000012846 protein folding Effects 0.000 description 4
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- XXQGYGJZNMSSFD-UHFFFAOYSA-N 2-[2-(dimethylcarbamoyl)phenoxy]acetic acid Chemical compound CN(C)C(=O)C1=CC=CC=C1OCC(O)=O XXQGYGJZNMSSFD-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
- G01N35/085—Flow Injection Analysis
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/986,140 US6054709A (en) | 1997-12-05 | 1997-12-05 | Method and apparatus for determining the rates of reactions in liquids by mass spectrometry |
| US08/986,140 | 1997-12-05 | ||
| PCT/CA1998/001120 WO1999030349A1 (en) | 1997-12-05 | 1998-12-03 | Method and apparatus for determining the rates of reactions in liquids by mass spectrometry |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001526398A true JP2001526398A (ja) | 2001-12-18 |
| JP2001526398A5 JP2001526398A5 (enExample) | 2006-02-02 |
Family
ID=25532120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000524808A Pending JP2001526398A (ja) | 1997-12-05 | 1998-12-03 | 質量分析法により液体中の反応速度を決定するための方法及び装置 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6054709A (enExample) |
| EP (1) | EP1036404B1 (enExample) |
| JP (1) | JP2001526398A (enExample) |
| AT (1) | ATE354173T1 (enExample) |
| AU (1) | AU1431099A (enExample) |
| CA (1) | CA2312891A1 (enExample) |
| DE (1) | DE69837106T2 (enExample) |
| WO (1) | WO1999030349A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005134187A (ja) * | 2003-10-29 | 2005-05-26 | Aida Eng Ltd | マイクロチップの微細流路における液体送液方法 |
| JP2019138855A (ja) * | 2018-02-14 | 2019-08-22 | 国立大学法人浜松医科大学 | イオン化装置、イオン化方法、プログラム、及び分析システム |
| JPWO2021020179A1 (enExample) * | 2019-07-31 | 2021-02-04 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6350987B1 (en) * | 1998-03-31 | 2002-02-26 | Dexter B. Northrup | Enzymatic reaction mechanisms by quenched-flow mass spectrometry |
| US6630664B1 (en) * | 1999-02-09 | 2003-10-07 | Syagen Technology | Atmospheric pressure photoionizer for mass spectrometry |
| ATE441190T1 (de) * | 2000-10-23 | 2009-09-15 | Univ Fraser Simon | Verfahren und vorrichtung zur erzeugung eines diskreten teilchens |
| JP4586275B2 (ja) * | 2001-01-17 | 2010-11-24 | 味の素株式会社 | 複合体の界面を同定する方法 |
| CA2387316A1 (en) * | 2002-05-31 | 2003-11-30 | The University Of Western Ontario | Method and apparatus for the detection of noncovalent interactions by mass spectrometry - based diffusion measurements |
| US20060228696A1 (en) * | 2002-06-27 | 2006-10-12 | Robert Rohwer | Methods for detecting and inactivating a prion |
| US7544932B2 (en) * | 2002-10-21 | 2009-06-09 | The United States Of America, As Represented By The Secretary, Of The Department Of Health And Human Services | Contiguous capillary electrospray sources and analytical devices |
| US20090068640A1 (en) * | 2003-06-27 | 2009-03-12 | Robert Rohwer | Methods for detecting and inactivating a prion |
| US6870154B1 (en) | 2004-02-27 | 2005-03-22 | The University Of Western Ontario | Capillary mixer with adjustable reaction chamber volume for mass spectrometry |
| US20140147921A1 (en) * | 2010-05-17 | 2014-05-29 | Ohio University | Microsecond time-resolved mass spectrometry |
| GB201019337D0 (en) * | 2010-11-16 | 2010-12-29 | Micromass Ltd | Controlling hydrogen-deuterium exchange on a spectrum by spectrum basis |
| JP2015522151A (ja) | 2012-07-07 | 2015-08-03 | クレオプティクス・アーゲーＣｒｅｏｐｔｉｘ Ａｇ | 生化学センサーのためのフロー導管システム |
| WO2014178418A1 (en) * | 2013-04-30 | 2014-11-06 | Canon Kabushiki Kaisha | Liquid droplet injecting apparatus and ion source |
| JP6323922B2 (ja) * | 2013-08-07 | 2018-05-16 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 質量分析計供給源中への液体流れからの気泡除去 |
| CN106683973A (zh) * | 2017-01-17 | 2017-05-17 | 中国科学技术大学 | 一种用于质谱仪的电喷雾电离源装置及系统 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5009849A (en) * | 1984-12-14 | 1991-04-23 | Monsanto Company | Apparatus for carrying out catalyzed chemical reactions and for studying catalysis |
| EP0211645B1 (en) * | 1985-08-21 | 1990-07-18 | Kratos Analytical Limited | Apparatus and methods for use in the mass analysis of chemical samples |
| US4861988A (en) * | 1987-09-30 | 1989-08-29 | Cornell Research Foundation, Inc. | Ion spray apparatus and method |
| US4935624A (en) * | 1987-09-30 | 1990-06-19 | Cornell Research Foundation, Inc. | Thermal-assisted electrospray interface (TAESI) for LC/MS |
| US5245186A (en) * | 1991-11-18 | 1993-09-14 | The Rockefeller University | Electrospray ion source for mass spectrometry |
| US5608217A (en) * | 1994-03-10 | 1997-03-04 | Bruker-Franzen Analytik Gmbh | Electrospraying method for mass spectrometric analysis |
| DE4415480C2 (de) * | 1994-05-02 | 1999-09-02 | Bruker Daltonik Gmbh | Vorrichtung und Verfahren zur massenspektrometrischen Untersuchung von Substanzgemischen durch Kopplung kapillarelektrophoretischer Separation (CE) mit Elektrospray-Ionisierung (ESI) |
-
1997
- 1997-12-05 US US08/986,140 patent/US6054709A/en not_active Expired - Fee Related
-
1998
- 1998-12-03 AT AT98958132T patent/ATE354173T1/de not_active IP Right Cessation
- 1998-12-03 AU AU14310/99A patent/AU1431099A/en not_active Abandoned
- 1998-12-03 DE DE69837106T patent/DE69837106T2/de not_active Expired - Fee Related
- 1998-12-03 EP EP98958132A patent/EP1036404B1/en not_active Expired - Lifetime
- 1998-12-03 WO PCT/CA1998/001120 patent/WO1999030349A1/en not_active Ceased
- 1998-12-03 JP JP2000524808A patent/JP2001526398A/ja active Pending
- 1998-12-03 CA CA002312891A patent/CA2312891A1/en not_active Abandoned
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005134187A (ja) * | 2003-10-29 | 2005-05-26 | Aida Eng Ltd | マイクロチップの微細流路における液体送液方法 |
| JP2019138855A (ja) * | 2018-02-14 | 2019-08-22 | 国立大学法人浜松医科大学 | イオン化装置、イオン化方法、プログラム、及び分析システム |
| JP7064746B2 (ja) | 2018-02-14 | 2022-05-11 | 国立大学法人浜松医科大学 | イオン化装置、イオン化方法、プログラム、及び分析システム |
| JPWO2021020179A1 (enExample) * | 2019-07-31 | 2021-02-04 | ||
| WO2021020179A1 (ja) * | 2019-07-31 | 2021-02-04 | 国立研究開発法人産業技術総合研究所 | スプレーイオン化装置、分析装置および表面塗布装置 |
| JP7186471B2 (ja) | 2019-07-31 | 2022-12-09 | 国立研究開発法人産業技術総合研究所 | スプレーイオン化装置、分析装置および表面塗布装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1036404B1 (en) | 2007-02-14 |
| EP1036404A1 (en) | 2000-09-20 |
| ATE354173T1 (de) | 2007-03-15 |
| US6054709A (en) | 2000-04-25 |
| AU1431099A (en) | 1999-06-28 |
| DE69837106D1 (de) | 2007-03-29 |
| DE69837106T2 (de) | 2007-08-30 |
| WO1999030349A1 (en) | 1999-06-17 |
| CA2312891A1 (en) | 1999-06-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20051205 |
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| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20051205 |
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| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090106 |
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| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20090602 |