DE69837106D1 - Verfahren und vorrichtung zur bestimmung von reaktionsraten in flüssigkeiten mittels massenspektrometrie - Google Patents

Verfahren und vorrichtung zur bestimmung von reaktionsraten in flüssigkeiten mittels massenspektrometrie

Info

Publication number
DE69837106D1
DE69837106D1 DE69837106T DE69837106T DE69837106D1 DE 69837106 D1 DE69837106 D1 DE 69837106D1 DE 69837106 T DE69837106 T DE 69837106T DE 69837106 T DE69837106 T DE 69837106T DE 69837106 D1 DE69837106 D1 DE 69837106D1
Authority
DE
Germany
Prior art keywords
determined
reactants
fluids
reaction time
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69837106T
Other languages
English (en)
Other versions
DE69837106T2 (de
Inventor
J Douglas
Lars Konermann
Bruce Collings
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of DE69837106D1 publication Critical patent/DE69837106D1/de
Application granted granted Critical
Publication of DE69837106T2 publication Critical patent/DE69837106T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G01N35/085—Flow Injection Analysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Electron Tubes For Measurement (AREA)
DE69837106T 1997-12-05 1998-12-03 Verfahren und vorrichtung zur bestimmung von reaktionsraten in flüssigkeiten mittels massenspektrometrie Expired - Fee Related DE69837106T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US986140 1997-12-05
US08/986,140 US6054709A (en) 1997-12-05 1997-12-05 Method and apparatus for determining the rates of reactions in liquids by mass spectrometry
PCT/CA1998/001120 WO1999030349A1 (en) 1997-12-05 1998-12-03 Method and apparatus for determining the rates of reactions in liquids by mass spectrometry

Publications (2)

Publication Number Publication Date
DE69837106D1 true DE69837106D1 (de) 2007-03-29
DE69837106T2 DE69837106T2 (de) 2007-08-30

Family

ID=25532120

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837106T Expired - Fee Related DE69837106T2 (de) 1997-12-05 1998-12-03 Verfahren und vorrichtung zur bestimmung von reaktionsraten in flüssigkeiten mittels massenspektrometrie

Country Status (8)

Country Link
US (1) US6054709A (de)
EP (1) EP1036404B1 (de)
JP (1) JP2001526398A (de)
AT (1) ATE354173T1 (de)
AU (1) AU1431099A (de)
CA (1) CA2312891A1 (de)
DE (1) DE69837106T2 (de)
WO (1) WO1999030349A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350987B1 (en) * 1998-03-31 2002-02-26 Dexter B. Northrup Enzymatic reaction mechanisms by quenched-flow mass spectrometry
US6630664B1 (en) * 1999-02-09 2003-10-07 Syagen Technology Atmospheric pressure photoionizer for mass spectrometry
CA2462265C (en) * 2000-10-23 2013-11-19 Simon Fraser University Method and apparatus for producing a discrete particle
JP4586275B2 (ja) * 2001-01-17 2010-11-24 味の素株式会社 複合体の界面を同定する方法
CA2387316A1 (en) * 2002-05-31 2003-11-30 The University Of Western Ontario Method and apparatus for the detection of noncovalent interactions by mass spectrometry - based diffusion measurements
WO2004003505A2 (en) * 2002-06-27 2004-01-08 University Of Marlyland, Baltimore Methods for detecting and inactivating a prion
WO2004038752A2 (en) * 2002-10-21 2004-05-06 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Contiguous capillary electrospray sources and analytical device
US20090068640A1 (en) * 2003-06-27 2009-03-12 Robert Rohwer Methods for detecting and inactivating a prion
JP3787578B2 (ja) * 2003-10-29 2006-06-21 アイダエンジニアリング株式会社 マイクロチップの微細流路における液体送液方法
US6870154B1 (en) 2004-02-27 2005-03-22 The University Of Western Ontario Capillary mixer with adjustable reaction chamber volume for mass spectrometry
US20140147921A1 (en) * 2010-05-17 2014-05-29 Ohio University Microsecond time-resolved mass spectrometry
GB201019337D0 (en) * 2010-11-16 2010-12-29 Micromass Ltd Controlling hydrogen-deuterium exchange on a spectrum by spectrum basis
CN104737025B (zh) 2012-07-07 2018-02-27 建奥迪斯有限公司 用于生物化学传感器的流动管道系统
KR20160003000A (ko) * 2013-04-30 2016-01-08 캐논 가부시끼가이샤 액적 토출 장치 및 이온원
JP6323922B2 (ja) * 2013-08-07 2018-05-16 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 質量分析計供給源中への液体流れからの気泡除去
CN106683973A (zh) * 2017-01-17 2017-05-17 中国科学技术大学 一种用于质谱仪的电喷雾电离源装置及系统
JP7064746B2 (ja) * 2018-02-14 2022-05-11 国立大学法人浜松医科大学 イオン化装置、イオン化方法、プログラム、及び分析システム
US20220250102A1 (en) * 2019-07-31 2022-08-11 National Institute Of Advanced Industrial Science And Technology Spray ionization device, analysis device, and surface coating device

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009849A (en) * 1984-12-14 1991-04-23 Monsanto Company Apparatus for carrying out catalyzed chemical reactions and for studying catalysis
DE3672710D1 (de) * 1985-08-21 1990-08-23 Kratos Analytical Ltd Vorrichtung und verfahren zum gebrauch bei der massenanalyse von chemischen proben.
US4861988A (en) * 1987-09-30 1989-08-29 Cornell Research Foundation, Inc. Ion spray apparatus and method
US4935624A (en) * 1987-09-30 1990-06-19 Cornell Research Foundation, Inc. Thermal-assisted electrospray interface (TAESI) for LC/MS
US5245186A (en) * 1991-11-18 1993-09-14 The Rockefeller University Electrospray ion source for mass spectrometry
US5608217A (en) * 1994-03-10 1997-03-04 Bruker-Franzen Analytik Gmbh Electrospraying method for mass spectrometric analysis
DE4415480C2 (de) * 1994-05-02 1999-09-02 Bruker Daltonik Gmbh Vorrichtung und Verfahren zur massenspektrometrischen Untersuchung von Substanzgemischen durch Kopplung kapillarelektrophoretischer Separation (CE) mit Elektrospray-Ionisierung (ESI)

Also Published As

Publication number Publication date
WO1999030349A1 (en) 1999-06-17
AU1431099A (en) 1999-06-28
ATE354173T1 (de) 2007-03-15
DE69837106T2 (de) 2007-08-30
CA2312891A1 (en) 1999-06-17
EP1036404A1 (de) 2000-09-20
EP1036404B1 (de) 2007-02-14
US6054709A (en) 2000-04-25
JP2001526398A (ja) 2001-12-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee