JP2001524067A - 放射線感作性タキサン類およびその医薬製剤 - Google Patents

放射線感作性タキサン類およびその医薬製剤

Info

Publication number
JP2001524067A
JP2001524067A JP51209497A JP51209497A JP2001524067A JP 2001524067 A JP2001524067 A JP 2001524067A JP 51209497 A JP51209497 A JP 51209497A JP 51209497 A JP51209497 A JP 51209497A JP 2001524067 A JP2001524067 A JP 2001524067A
Authority
JP
Japan
Prior art keywords
rsg
heteroaryl
hydrocarbon
hydrogen
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP51209497A
Other languages
English (en)
Japanese (ja)
Inventor
ホルトン，ロバート・エイ
ナディザデー，ホサイン
ホファー，カート・ジー
ヤン，リ−シ
Original Assignee
フロリダ・ステイト・ユニバーシティ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by フロリダ・ステイト・ユニバーシティ filed Critical フロリダ・ステイト・ユニバーシティ
Priority claimed from PCT/US1996/014613 external-priority patent/WO1997009979A1/fr
Publication of JP2001524067A publication Critical patent/JP2001524067A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP51209497A 1995-09-13 1996-09-13 放射線感作性タキサン類およびその医薬製剤 Pending JP2001524067A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US368795P 1995-09-13 1995-09-13
US60/003,687 1995-09-13
PCT/US1996/014613 WO1997009979A1 (fr) 1995-09-13 1996-09-13 Taxanes a effet radiosensibilisant et leurs preparations pharmaceutiques

Publications (1)

Publication Number Publication Date
JP2001524067A true JP2001524067A (ja) 2001-11-27

Family

ID=34810323

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51209497A Pending JP2001524067A (ja) 1995-09-13 1996-09-13 放射線感作性タキサン類およびその医薬製剤

Country Status (3)

Country Link
EP (1) EP0855909A4 (fr)
JP (1) JP2001524067A (fr)
AU (1) AU728057B2 (fr)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
AU663732B2 (en) * 1991-09-23 1995-10-19 Bristol-Myers Squibb Company 10-desacetoxytaxol derivatives
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
AU2333892A (en) * 1992-01-31 1993-09-01 Trustees Of Columbia University In The City Of New York, The Taxol as a radiation sensitizer
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
PT1227093E (pt) * 1993-03-22 2005-09-30 Univ Florida State Beta-cactamas uteis para a preparacao de taxanos possuindo cadeia lateral substituida com furilo ou tienilo
US5780653A (en) * 1995-06-07 1998-07-14 Vivorx Pharmaceuticals, Inc. Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers

Also Published As

Publication number Publication date
EP0855909A1 (fr) 1998-08-05
AU728057B2 (en) 2001-01-04
EP0855909A4 (fr) 2000-06-07
AU6974696A (en) 1997-04-01

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