|
US7232899B2
(en)
|
1996-09-25 |
2007-06-19 |
The Scripps Research Institute |
Adenovirus vectors, packaging cell lines, compositions, and methods for preparation and use
|
|
AU4070499A
(en)
|
1998-04-30 |
1999-11-16 |
Cornell Research Foundation Inc. |
Adenoviral vectors with tandem fiber proteins
|
|
US6455314B1
(en)
|
1998-09-11 |
2002-09-24 |
Genvec, Inc. |
Alternatively targeted adenovirus
|
|
IL133032A
(en)
*
|
1998-11-20 |
2007-06-03 |
Introgene Bv |
Adenoviral gene delivery vectors provided with a tissue tropism for smooth muscle cells and /or endothelial cells
|
|
EP1020529B1
(en)
*
|
1998-11-20 |
2005-06-01 |
Crucell Holland B.V. |
Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
|
|
JP2000279178A
(ja)
*
|
1999-02-24 |
2000-10-10 |
Japan Found Cancer Res |
ウイルスベクター
|
|
DE19932688B4
(de)
|
1999-07-13 |
2009-10-08 |
Scil Proteins Gmbh |
Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen
|
|
AU783879B2
(en)
*
|
1999-11-25 |
2005-12-15 |
Transgene S.A. |
Modified adenovirus fibre and uses
|
|
AU6368901A
(en)
*
|
2000-05-31 |
2001-12-11 |
Univ Saskatchewan |
Modified bovine adenovirus having altered tropism
|
|
AU2001283832A1
(en)
*
|
2000-06-02 |
2001-12-11 |
Novartis Ag |
Adenovirus particles with mutagenized fiber proteins
|
|
US20060228334A1
(en)
*
|
2002-07-10 |
2006-10-12 |
Manuel Rosa-Calatrava |
Modified adenoviral fiber with ablated to cellular receptors
|
|
US20060281090A1
(en)
*
|
2003-05-01 |
2006-12-14 |
University Of Washington Uw Tech Transfer- Invention Licensing |
Capsid-modified adenovirus vectors and methods of using the same
|
|
JP2007503843A
(ja)
*
|
2003-05-14 |
2007-03-01 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
アデノウイルス親和性の拡大
|
|
DE10324447A1
(de)
|
2003-05-28 |
2004-12-30 |
Scil Proteins Gmbh |
Generierung künstlicher Bindungsproteine auf der Grundlage von Ubiquitin
|
|
GB0313132D0
(en)
*
|
2003-06-06 |
2003-07-09 |
Ich Productions Ltd |
Peptide ligands
|
|
WO2005030927A2
(en)
*
|
2003-09-23 |
2005-04-07 |
Uab Research Foundation |
Methods and compositions for in vivo inflammation monitoring
|
|
DE602005017743D1
(de)
*
|
2004-01-23 |
2009-12-31 |
Angeletti P Ist Richerche Bio |
Impfstoffträger für schimpansen-adenovirus
|
|
DE102004049479A1
(de)
|
2004-10-11 |
2006-04-13 |
Scil Proteins Gmbh |
Proteinkonjugate zur Verwendung in Therapie, Diagnose und Chromatographie
|
|
US20070010016A1
(en)
*
|
2005-03-11 |
2007-01-11 |
Mccelland Alan |
Gene transfer with adenoviruses having modified fiber proteins
|
|
WO2006133911A2
(en)
*
|
2005-06-17 |
2006-12-21 |
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa |
Hepatitis c virus nucleic acid vaccine
|
|
WO2007094653A1
(en)
*
|
2006-02-13 |
2007-08-23 |
Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg |
Adenovirus particles having a chimeric adenovirus spike protein, use thereof and methods for producing such particles.
|
|
EP1925664A1
(en)
*
|
2006-11-15 |
2008-05-28 |
Scil proteins GmbH |
Artificial binding proteins based on a modified alpha helical region of ubiquitin
|
|
WO2009111738A2
(en)
|
2008-03-06 |
2009-09-11 |
Mayo Foundation For Medical Education And Research |
Single cycle replicating adenovirus vectors
|
|
RU2553333C2
(ru)
|
2009-12-14 |
2015-06-10 |
Сцил Протеинс Гмбх |
Способ идентификации гетеромультимерных модифицированных убиквитиновых белков со способностью связываться с лигандами
|
|
CA2837804C
(en)
|
2011-06-15 |
2018-03-20 |
Scil Proteins Gmbh |
Dimeric binding proteins based on modified ubiquitins
|
|
SG11201507393TA
(en)
|
2013-03-14 |
2015-10-29 |
Salk Inst For Biological Studi |
Oncolytic adenovirus compositions
|
|
KR102608590B1
(ko)
|
2014-09-24 |
2023-12-01 |
솔크 인스티튜트 포 바이올로지칼 스터디즈 |
종양 살상 바이러스 및 이의 사용방법
|
|
JP6738340B2
(ja)
|
2015-02-06 |
2020-08-12 |
ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH |
新規なegfr結合タンパク質
|
|
JP6856938B2
(ja)
|
2015-07-16 |
2021-04-14 |
ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH |
新規な免疫グロブリン結合タンパク質およびアフィニティ精製におけるそれらの使用
|
|
WO2017013136A1
(en)
|
2015-07-20 |
2017-01-26 |
Scil Proteins Gmbh |
Novel binding proteins based on di-ubiquitin muteins and methods for generation
|
|
WO2017147265A1
(en)
|
2016-02-23 |
2017-08-31 |
Salk Institute For Biological Studies |
High throughput assay for measuring adenovirus replication kinetics
|
|
WO2017147269A1
(en)
|
2016-02-23 |
2017-08-31 |
Salk Institute For Biological Studies |
Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
|
|
US11813336B2
(en)
|
2016-05-04 |
2023-11-14 |
Navigo Proteins Gmbh |
Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker
|
|
CN109963864B
(zh)
|
2016-08-11 |
2024-01-02 |
瑞普利金公司 |
用于亲和色谱的碱性稳定性fc结合蛋白
|
|
EP4485466A3
(en)
|
2016-08-17 |
2025-04-02 |
The Broad Institute Inc. |
Novel crispr enzymes and systems
|
|
WO2018035387A1
(en)
|
2016-08-17 |
2018-02-22 |
The Broad Institute, Inc. |
Novel crispr enzymes and systems
|
|
EP3532082A4
(en)
|
2016-12-12 |
2020-08-26 |
Salk Institute for Biological Studies |
SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES
|
|
WO2018191750A2
(en)
|
2017-04-14 |
2018-10-18 |
The Broad Institute Inc. |
Novel delivery of large payloads
|
|
WO2019135816A2
(en)
|
2017-10-23 |
2019-07-11 |
The Broad Institute, Inc. |
Novel nucleic acid modifiers
|
|
US11414466B2
(en)
|
2017-11-07 |
2022-08-16 |
Navigo Proteins Gmbh |
Fusion proteins with specificity for ED-B and long serum half-life for diagnosis or treatment of cancer
|
|
EP3710039A4
(en)
|
2017-11-13 |
2021-08-04 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER BY TARGETING THE CLEC2D-KLRB1 PATH
|
|
CN112292449A
(zh)
|
2018-04-09 |
2021-01-29 |
萨克生物研究学院 |
具有增强的复制特性的溶瘤腺病毒组合物
|
|
CN113544266A
(zh)
|
2018-12-17 |
2021-10-22 |
博德研究所 |
Crispr相关转座酶系统和其使用方法
|
|
MX2021007283A
(es)
|
2018-12-18 |
2021-07-15 |
Navigo Proteins Gmbh |
Proteinas de union especificas del folr1 novedosas para diagnostico y tratamiento del cancer.
|
|
WO2020236972A2
(en)
|
2019-05-20 |
2020-11-26 |
The Broad Institute, Inc. |
Non-class i multi-component nucleic acid targeting systems
|
|
US12297426B2
(en)
|
2019-10-01 |
2025-05-13 |
The Broad Institute, Inc. |
DNA damage response signature guided rational design of CRISPR-based systems and therapies
|
|
US11149286B1
(en)
|
2020-08-17 |
2021-10-19 |
Mayo Foundation For Medical Education And Research |
Adenovirus vectors and methods for using adenovirus vectors
|
|
IL316038A
(en)
|
2022-04-04 |
2024-11-01 |
Univ California |
Preparations and methods for genetic complementation
|
|
WO2025072383A1
(en)
|
2023-09-25 |
2025-04-03 |
The Broad Institute, Inc. |
Viral open reading frames, uses thereof, and methods of detecting the same
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025129158A1
(en)
|
2023-12-15 |
2025-06-19 |
The Broad Institute, Inc. |
Engineered arc delivery vesicles and uses thereof
|
|
WO2025250808A1
(en)
|
2024-05-29 |
2025-12-04 |
The Brigham And Women’S Hospital, Inc. |
Anti-crispr delivery compositions and methods
|