JP2001511807A5 - - Google Patents

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Publication number
JP2001511807A5
JP2001511807A5 JP1998535835A JP53583598A JP2001511807A5 JP 2001511807 A5 JP2001511807 A5 JP 2001511807A5 JP 1998535835 A JP1998535835 A JP 1998535835A JP 53583598 A JP53583598 A JP 53583598A JP 2001511807 A5 JP2001511807 A5 JP 2001511807A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998535835A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001511807A (ja
JP4311765B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/002375 external-priority patent/WO1998035940A1/en
Publication of JP2001511807A publication Critical patent/JP2001511807A/ja
Publication of JP2001511807A5 publication Critical patent/JP2001511807A5/ja
Application granted granted Critical
Publication of JP4311765B2 publication Critical patent/JP4311765B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP53583598A 1997-02-14 1998-02-11 高親油性カンプトテシン誘導体 Expired - Lifetime JP4311765B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3714897P 1997-02-14 1997-02-14
US60/037,148 1997-02-14
PCT/US1998/002375 WO1998035940A1 (en) 1997-02-14 1998-02-11 Highly lipophilic camptothecin derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009047622A Division JP5264561B2 (ja) 1997-02-14 2009-03-02 高親油性カンプトテシン誘導体

Publications (3)

Publication Number Publication Date
JP2001511807A JP2001511807A (ja) 2001-08-14
JP2001511807A5 true JP2001511807A5 (https=) 2005-10-06
JP4311765B2 JP4311765B2 (ja) 2009-08-12

Family

ID=21892705

Family Applications (2)

Application Number Title Priority Date Filing Date
JP53583598A Expired - Lifetime JP4311765B2 (ja) 1997-02-14 1998-02-11 高親油性カンプトテシン誘導体
JP2009047622A Expired - Lifetime JP5264561B2 (ja) 1997-02-14 2009-03-02 高親油性カンプトテシン誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009047622A Expired - Lifetime JP5264561B2 (ja) 1997-02-14 2009-03-02 高親油性カンプトテシン誘導体

Country Status (10)

Country Link
EP (1) EP1017675B1 (https=)
JP (2) JP4311765B2 (https=)
AT (1) ATE329903T1 (https=)
AU (1) AU6272598A (https=)
CA (1) CA2280905C (https=)
DE (1) DE69834923T2 (https=)
DK (1) DK1017675T3 (https=)
ES (1) ES2262223T3 (https=)
PT (1) PT1017675E (https=)
WO (1) WO1998035940A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150343A (en) * 1993-06-30 2000-11-21 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6136978A (en) * 1993-06-30 2000-10-24 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6743917B2 (en) 1993-06-30 2004-06-01 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
FR2790261B1 (fr) * 1999-02-26 2004-09-10 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
ATE329903T1 (de) * 1997-02-14 2006-07-15 Bionumerik Pharmaceuticals Inc Hochgradig lipophile camptothecin-derivate
US6057303A (en) * 1998-10-20 2000-05-02 Bionumerik Pharmaceuticals, Inc. Highly lipophilic Camptothecin derivatives
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
WO2000066127A1 (en) * 1999-05-04 2000-11-09 Bionumerik Pharmaceuticals, Inc. Novel highly lipophilic camptothecin analogs
US6350756B1 (en) * 2001-01-18 2002-02-26 California Pacific Medical Center Camptothecin derivatives
US6855720B2 (en) 2001-03-01 2005-02-15 California Pacific Medical Center Nitrogen-based camptothecin derivatives
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
DE60227113D1 (de) 2001-11-30 2008-07-24 Chugai Pharmaceutical Co Ltd Kondensierte camptothecine als antitumormittel
US6933302B2 (en) 2002-06-03 2005-08-23 California Pacific Medical Center Nitrogen-based homo-camptothecin derivatives
EP1393719A1 (en) * 2002-08-23 2004-03-03 Munich Biotech AG Camptothecin-carboxylate formulations
US7067666B2 (en) * 2003-06-27 2006-06-27 Research Triangle Institute 7-substituted camptothecin and camptothecin analogs and methods for producing the same
WO2005060871A1 (en) * 2003-12-17 2005-07-07 Bionumerik Pharmaceuticals, Inc. Pharmaceutical formulations of camptothecins and process for making same
RU2413731C2 (ru) 2004-04-09 2011-03-10 Чугаи Сейяку Кабусики Кайся Новые растворимые в воде пролекарства
ITRM20040240A1 (it) * 2004-05-13 2004-08-13 Ist Naz Stud Cura Dei Tumori Camptotecine coniugate in posizione 7 con antagonisti delle integrine.
TW200744603A (en) 2005-08-22 2007-12-16 Chugai Pharmaceutical Co Ltd Novel anticancer concomitant drug
US7875602B2 (en) 2005-10-21 2011-01-25 Sutter West Bay Hospitals Camptothecin derivatives as chemoradiosensitizing agents
WO2007075492A1 (en) * 2005-12-16 2007-07-05 Sonus Pharmaceuticals, Inc. Lipophilic anticancer drug compounds
CN101522686A (zh) * 2006-08-11 2009-09-02 克里斯特斯斯特林癌症研究基金会 制备喜树碱酯的方法
CN103068404B (zh) 2010-06-11 2015-11-25 独立行政法人科学技术振兴机构 药物多聚物微粒及其制造方法
WO2014067960A2 (en) * 2012-10-30 2014-05-08 Nerviano Medical Sciences S.R.L. Functionalized 9-bromo-camptothecin derivatives
FR3029637B1 (fr) 2014-12-05 2018-01-05 Universite De Strasbourg Microdispositif de detection de composes organiques volatils et methode de detection d'au moins un compose organique volatil compris dans un echantillon gazeux
WO2025077773A1 (zh) * 2023-10-10 2025-04-17 上海翊维康医药有限责任公司 新的i型拓扑异构酶抑制剂及其制备方法和用途
WO2025252101A1 (zh) * 2024-06-05 2025-12-11 荣昌生物制药(烟台)股份有限公司 一种喜树碱类化合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
JPH0615547B2 (ja) * 1988-01-20 1994-03-02 株式会社ヤクルト本社 新規なカンプトテシン誘導体
US5446047A (en) * 1992-07-23 1995-08-29 Sloan-Kettering Institute For Cancer Research Camptothecin analogues
US5468754A (en) * 1994-04-19 1995-11-21 Bionumerik Pharmaceuticals, Inc. 11,7 substituted camptothecin derivatives and formulations of 11,7 substituted camptothecin derivatives and methods for uses thereof
GB9510716D0 (en) * 1995-05-26 1995-07-19 Pharmacia Spa Substituted camptothecin derivatives and process for their preparation
ATE329903T1 (de) * 1997-02-14 2006-07-15 Bionumerik Pharmaceuticals Inc Hochgradig lipophile camptothecin-derivate

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