FR2761689B1 - Fibre adenovirale modifiee et adenovirus cibles - Google Patents

Fibre adenovirale modifiee et adenovirus cibles

Info

Publication number
FR2761689B1
FR2761689B1 FR9704747A FR9704747A FR2761689B1 FR 2761689 B1 FR2761689 B1 FR 2761689B1 FR 9704747 A FR9704747 A FR 9704747A FR 9704747 A FR9704747 A FR 9704747A FR 2761689 B1 FR2761689 B1 FR 2761689B1
Authority
FR
France
Prior art keywords
adenovirus
fiber
adenoviral fiber
residues
modified adenoviral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9704747A
Other languages
English (en)
French (fr)
Other versions
FR2761689A1 (fr
Inventor
Valerie Legrand
Majid Mehtali
Pierre Boulanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9703987A external-priority patent/FR2761688A1/fr
Application filed by Transgene SA filed Critical Transgene SA
Priority to FR9704747A priority Critical patent/FR2761689B1/fr
Priority to DE69831741T priority patent/DE69831741T2/de
Priority to JP54126098A priority patent/JP2001522236A/ja
Priority to US09/402,401 priority patent/US6569677B1/en
Priority to CA002285565A priority patent/CA2285565A1/fr
Priority to EP98917294A priority patent/EP0991763B1/fr
Priority to ES98917294T priority patent/ES2246533T3/es
Priority to DK98917294T priority patent/DK0991763T3/da
Priority to PCT/FR1998/000668 priority patent/WO1998044121A1/fr
Priority to AT98917294T priority patent/ATE305513T1/de
Priority to AU70547/98A priority patent/AU741728B2/en
Publication of FR2761689A1 publication Critical patent/FR2761689A1/fr
Publication of FR2761689B1 publication Critical patent/FR2761689B1/fr
Application granted granted Critical
Priority to US10/402,954 priority patent/US7256036B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10345—Special targeting system for viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
    • C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
    • C12N2810/851—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from growth factors; from growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Processing Of Solid Wastes (AREA)
FR9704747A 1997-04-02 1997-04-17 Fibre adenovirale modifiee et adenovirus cibles Expired - Fee Related FR2761689B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR9704747A FR2761689B1 (fr) 1997-04-02 1997-04-17 Fibre adenovirale modifiee et adenovirus cibles
ES98917294T ES2246533T3 (es) 1997-04-02 1998-04-02 Fibra adenovirica modificada y adenovirus dianas.
PCT/FR1998/000668 WO1998044121A1 (fr) 1997-04-02 1998-04-02 Fibre adenovirale modifiee et adenovirus cibles
US09/402,401 US6569677B1 (en) 1997-04-02 1998-04-02 Modified adenoviral fiber and target adenoviruses
CA002285565A CA2285565A1 (fr) 1997-04-02 1998-04-02 Fibre adenovirale modifiee et adenovirus cibles
EP98917294A EP0991763B1 (fr) 1997-04-02 1998-04-02 Fibre adenovirale modifiee et adenovirus cibles
DE69831741T DE69831741T2 (de) 1997-04-02 1998-04-02 Modifizierte adenovirale fiber und sie enthaltende adenoviren
DK98917294T DK0991763T3 (da) 1997-04-02 1998-04-02 Modificeret adenovirusfiber og måladenovirus
JP54126098A JP2001522236A (ja) 1997-04-02 1998-04-02 改変アデノウイルスファイバーおよび標的アデノウイルス
AT98917294T ATE305513T1 (de) 1997-04-02 1998-04-02 Modifizierte adenovirale fiber und sie enthaltende adenoviren
AU70547/98A AU741728B2 (en) 1997-04-02 1998-04-02 Modified adenoviral fiber and target adenoviruses
US10/402,954 US7256036B2 (en) 1997-04-02 2003-04-01 Modified adenoviral fiber and target adenoviruses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9703987A FR2761688A1 (fr) 1997-04-02 1997-04-02 Fibre adenovirale modifiee et adenovirus cibles
FR9704747A FR2761689B1 (fr) 1997-04-02 1997-04-17 Fibre adenovirale modifiee et adenovirus cibles

Publications (2)

Publication Number Publication Date
FR2761689A1 FR2761689A1 (fr) 1998-10-09
FR2761689B1 true FR2761689B1 (fr) 1999-06-25

Family

ID=26233432

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9704747A Expired - Fee Related FR2761689B1 (fr) 1997-04-02 1997-04-17 Fibre adenovirale modifiee et adenovirus cibles

Country Status (11)

Country Link
US (2) US6569677B1 (https=)
EP (1) EP0991763B1 (https=)
JP (1) JP2001522236A (https=)
AT (1) ATE305513T1 (https=)
AU (1) AU741728B2 (https=)
CA (1) CA2285565A1 (https=)
DE (1) DE69831741T2 (https=)
DK (1) DK0991763T3 (https=)
ES (1) ES2246533T3 (https=)
FR (1) FR2761689B1 (https=)
WO (1) WO1998044121A1 (https=)

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AU2014236207B2 (en) 2013-03-14 2019-05-23 Salk Institute For Biological Studies Oncolytic adenovirus compositions
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JP6738340B2 (ja) 2015-02-06 2020-08-12 ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ 新規なｅｇｆｒ結合タンパク質
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Also Published As

Publication number Publication date
US20030175243A1 (en) 2003-09-18
US6569677B1 (en) 2003-05-27
EP0991763A1 (fr) 2000-04-12
FR2761689A1 (fr) 1998-10-09
US7256036B2 (en) 2007-08-14
CA2285565A1 (fr) 1998-10-08
ES2246533T3 (es) 2006-02-16
AU7054798A (en) 1998-10-22
JP2001522236A (ja) 2001-11-13
ATE305513T1 (de) 2005-10-15
DE69831741T2 (de) 2006-07-06
DE69831741D1 (de) 2006-02-09
WO1998044121A1 (fr) 1998-10-08
AU741728B2 (en) 2001-12-06
EP0991763B1 (fr) 2005-09-28
DK0991763T3 (da) 2006-02-20

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