|
DE69638023D1
(de)
|
1995-06-28 |
2009-10-22 |
Univ Yale |
Nukleotid- und proteinsequenzen von delta-genen von vertebraten und darauf basierende methoden
|
|
US5780300A
(en)
*
|
1995-09-29 |
1998-07-14 |
Yale University |
Manipulation of non-terminally differentiated cells using the notch pathway
|
|
US20060122373A1
(en)
|
1997-04-04 |
2006-06-08 |
Millennium Pharmaceuticals, Inc. |
Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof
|
|
US6664098B1
(en)
*
|
1997-05-14 |
2003-12-16 |
Asahi Kasei Kabushiki Kaisha |
Differentiation inhibitory agent
|
|
EP1100899A2
(en)
*
|
1998-07-27 |
2001-05-23 |
Amgen Inc. |
Delta-related polypeptides
|
|
AU6913100A
(en)
*
|
1999-08-19 |
2001-03-13 |
Chiron Corporation |
Notch receptor ligands and uses thereof
|
|
US6703221B1
(en)
|
1999-08-19 |
2004-03-09 |
Chiron Corporation |
Notch receptor ligands and uses thereof
|
|
GB9927328D0
(en)
|
1999-11-18 |
2000-01-12 |
Lorantis Ltd |
Immunotherapy
|
|
GB9927331D0
(en)
|
1999-11-18 |
2000-01-12 |
Fluorescience Ltd |
Assay for measuring enzyme activity in vivo
|
|
US6984522B2
(en)
|
2000-08-03 |
2006-01-10 |
Regents Of The University Of Michigan |
Isolation and use of solid tumor stem cells
|
|
US8044259B2
(en)
|
2000-08-03 |
2011-10-25 |
The Regents Of The University Of Michigan |
Determining the capability of a test compound to affect solid tumor stem cells
|
|
CA2457879A1
(en)
*
|
2001-08-22 |
2003-03-06 |
Galapagos Genomics N.V. |
Modulators of bone homeostasis identified in a high-throughput screen
|
|
JP2003245084A
(ja)
|
2001-12-20 |
2003-09-02 |
Morinaga Milk Ind Co Ltd |
脳梁又は精子の形成不全の診断及び治療に有用な新規遺伝子、並びにその用途
|
|
US8048418B2
(en)
|
2004-10-29 |
2011-11-01 |
Regeneron Pharmaceuticals, Inc. |
Therapeutic methods for inhibiting tumor growth with combination of Dll4 antagonists and VEGF antagonists
|
|
US7906116B2
(en)
|
2005-09-01 |
2011-03-15 |
Parkash Gill |
Methods for using and identifying modulators of Delta-like 4
|
|
CA2628221A1
(en)
|
2005-10-31 |
2007-05-10 |
Oncomed Pharmaceuticals, Inc. |
Anti-frizzled receptor antibodies for treating cancer
|
|
US7723477B2
(en)
|
2005-10-31 |
2010-05-25 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
|
|
NZ572177A
(en)
|
2006-06-06 |
2012-02-24 |
Genentech Inc |
Anti-dll4 antibodies and methods using same
|
|
DK2066694T3
(en)
|
2006-09-29 |
2016-02-08 |
Oncomed Pharm Inc |
Compositions and Methods for Diagnosing and Treating Cancer
|
|
RU2448979C2
(ru)
|
2006-12-14 |
2012-04-27 |
Ридженерон Фармасьютикалз, Инк. |
Антитела человека к дельта-подобному лиганду-4 человека
|
|
WO2008092002A2
(en)
|
2007-01-24 |
2008-07-31 |
The Regents Of The University Of Michigan |
Compositions and methods for treating and diagnosing pancreatic cancer
|
|
SG190568A1
(en)
|
2008-09-26 |
2013-06-28 |
Oncomed Pharm Inc |
Frizzled-binding agents and uses thereof
|
|
CA2742969A1
(en)
|
2008-11-07 |
2010-05-14 |
Fabrus Llc |
Anti-dll4 antibodies and uses thereof
|
|
HUE029661T2
(en)
|
2009-10-16 |
2017-03-28 |
Oncomed Pharm Inc |
A therapeutic combination and use of DLL4 antagonist antibodies and antihypertensive agents
|
|
TWI535445B
(zh)
|
2010-01-12 |
2016-06-01 |
安可美德藥物股份有限公司 |
Wnt拮抗劑及治療和篩選方法
|
|
DK2530091T3
(en)
|
2010-01-29 |
2018-05-28 |
Chugai Pharmaceutical Co Ltd |
ANTI-DLL3 ANTIBODY
|
|
CA2794674A1
(en)
|
2010-04-01 |
2011-10-06 |
Oncomed Pharmaceuticals, Inc. |
Frizzled-binding agents and uses thereof
|
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
|
LT3485903T
(lt)
|
2011-09-23 |
2023-02-27 |
Mereo Biopharma 5, Inc. |
Vegf/ dll4 surišantys agentai ir jų panaudojimas
|
|
AU2013334790A1
(en)
|
2012-10-23 |
2015-04-30 |
Oncomed Pharmaceuticals, Inc. |
Methods of treating neuroendocrine tumors using Wnt pathway-binding agents
|
|
US9599620B2
(en)
|
2012-10-31 |
2017-03-21 |
Oncomed Pharmaceuticals, Inc. |
Methods and monitoring of treatment with a DLL4 antagonist
|
|
AU2014212081A1
(en)
|
2013-02-04 |
2015-08-13 |
Oncomed Pharmaceuticals, Inc. |
Methods and monitoring of treatment with a Wnt pathway inhibitor
|
|
US9168300B2
(en)
|
2013-03-14 |
2015-10-27 |
Oncomed Pharmaceuticals, Inc. |
MET-binding agents and uses thereof
|
|
ES2808153T3
(es)
|
2014-10-31 |
2021-02-25 |
Mereo Biopharma 5 Inc |
Terapia de combinación para tratamiento de enfermedad
|
|
US11339213B2
(en)
|
2015-09-23 |
2022-05-24 |
Mereo Biopharma 5, Inc. |
Methods and compositions for treatment of cancer
|
|
JP7314146B2
(ja)
|
2017-12-28 |
2023-07-25 |
中外製薬株式会社 |
細胞傷害誘導治療剤
|