JP2001520509A - 自己免疫細胞療法:細胞組成物、方法およびヒト疾患の治療への応用 - Google Patents

自己免疫細胞療法:細胞組成物、方法およびヒト疾患の治療への応用

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Publication number
JP2001520509A
JP2001520509A JP50770697A JP50770697A JP2001520509A JP 2001520509 A JP2001520509 A JP 2001520509A JP 50770697 A JP50770697 A JP 50770697A JP 50770697 A JP50770697 A JP 50770697A JP 2001520509 A JP2001520509 A JP 2001520509A
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cells
cell
composition
immune
patient
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グルーエンバーグ,マイケル・エル
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セルセラピー・インコーポレイテツド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/462Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4621Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/46433Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/464838Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
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    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • CCHEMISTRY; METALLURGY
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/24Interferons [IFN]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/51B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/515CD3, T-cell receptor complex
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/599Cell markers; Cell surface determinants with CD designations not provided for elsewhere

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
JP50770697A 1995-07-25 1996-07-24 自己免疫細胞療法:細胞組成物、方法およびヒト疾患の治療への応用 Ceased JP2001520509A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50666895A 1995-07-25 1995-07-25
US506,668 1995-07-26
PCT/US1996/012170 WO1997005239A1 (fr) 1995-07-25 1996-07-24 Immunotherapie par cellules autologues: compositions cellulaires , methodes et application au traitement d'une maladie humaine

Publications (1)

Publication Number Publication Date
JP2001520509A true JP2001520509A (ja) 2001-10-30

Family

ID=24015526

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50770697A Ceased JP2001520509A (ja) 1995-07-25 1996-07-24 自己免疫細胞療法:細胞組成物、方法およびヒト疾患の治療への応用

Country Status (5)

Country Link
EP (1) EP0852618A1 (fr)
JP (1) JP2001520509A (fr)
AU (1) AU6649996A (fr)
CA (1) CA2227327A1 (fr)
WO (1) WO1997005239A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005108554A1 (fr) * 2004-05-11 2005-11-17 Shukokai Incorporated Immunocyte adoptif pour vaccin antitumoral et similaire
JP2008120724A (ja) * 2006-11-10 2008-05-29 Japan Science & Technology Agency Th2型アレルギー性疾患治療薬及び感染症治療薬
JP2021058200A (ja) * 2015-05-13 2021-04-15 テルモ ビーシーティー、インコーポレーテッド 細胞の増殖

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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WO1999021887A2 (fr) * 1997-10-23 1999-05-06 Klehr Nikolaus W Procede pour la production de cytokines de sang autologue humain
EP1030674A1 (fr) * 1997-11-10 2000-08-30 Arch Development Corporation METHODES DE TRAITEMENT DE TUMEURS ET DE CELLULES TUMORALES FAISANT APPEL A DES LYMPHOCYTES T ACTIVES $i(EX VIVO)
US6610542B1 (en) * 1998-04-24 2003-08-26 Hemosol Inc. Efficient ex vivo expansion of cd4+ and cd8− T-cells from HIV infected subjects
DE69941150D1 (de) 1998-05-11 2009-09-03 Miltenyi Biotec Gmbh Verfahren zur direkten auswahl von antigen-spezifischen t-zellen
WO2000000587A1 (fr) * 1998-06-26 2000-01-06 Keld Kaltoft Methode de developpement et de selection des lymphocytes t associes a une pathologie
US6406699B1 (en) * 1999-10-05 2002-06-18 Gary W. Wood Composition and method of cancer antigen immunotherapy
GB9928193D0 (en) * 1999-11-29 2000-01-26 Univ Bristol Cell treatment method
US6797514B2 (en) 2000-02-24 2004-09-28 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
US6867041B2 (en) 2000-02-24 2005-03-15 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
CN100510060C (zh) 2001-08-15 2009-07-08 宝生物工程株式会社 抗原特异性细胞毒性t细胞的扩大培养方法
AU2002336417A1 (en) * 2001-08-31 2003-03-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Methods of generating human cd4+ th1 cells
US20030134415A1 (en) * 2001-09-19 2003-07-17 Gruenberg Micheal L. Th1 cell adoptive immunotherapy
US20030175272A1 (en) * 2002-03-07 2003-09-18 Medcell Biologics, Inc. Re-activated T-cells for adoptive immunotherapy
US20030170238A1 (en) * 2002-03-07 2003-09-11 Gruenberg Micheal L. Re-activated T-cells for adoptive immunotherapy
ATE491021T1 (de) 2002-03-25 2010-12-15 Takara Bio Inc Verfahren zur produktion eines zytotoxischen lymphozyten
US20050084967A1 (en) 2002-06-28 2005-04-21 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
AU2003265948B8 (en) 2002-09-06 2009-09-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Immunotherapy with in vitro-selected antigen-specific lymphocytes after nonmyeloablative lymphodepleting chemotherapy
AU2003300359A1 (en) 2003-05-08 2004-12-13 Xcyte Therapies, Inc. Generation and isolation of antigen-specific t cells
US7435592B2 (en) 2003-05-13 2008-10-14 Immunovative Therapies, Ltd. Compositions for allogeneic cell therapy
US20070025961A1 (en) 2003-06-03 2007-02-01 Kenzo Bamba Composition for stabilizing survival of transplanted hematopoietic stem cell, kit for obtaining the composition, method of stabilizing survival of transplanted hematopoietic stem cell, human monoclonal antibody or human polyclonal antibody and method of producing the same, gene encoding human monoclonal antibody and transf
WO2005007116A2 (fr) * 2003-07-18 2005-01-27 Valeocyte Therapies Llc Systemes de cellules presentant l'antigene artificielles
DE602004025591D1 (de) 2003-08-22 2010-04-01 Takara Bio Inc Verfahren zur herstellung zytotoxischer lymphozyten
CN101243187B (zh) 2005-08-17 2012-07-11 宝生物工程株式会社 淋巴细胞的制备方法
EP2361930A3 (fr) 2007-03-26 2011-10-26 Dako Denmark A/S Multimeres du complexes peptide-cmh et leur utilisation dans des maladies infectieuses de borrelia
EP2167536A1 (fr) 2007-07-03 2010-03-31 Dako Denmark A/S Procedes ameliores pour produire, marquer et utiliser des multimeres du cmh
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
US10968269B1 (en) 2008-02-28 2021-04-06 Agilent Technologies, Inc. MHC multimers in borrelia diagnostics and disease
US10722562B2 (en) 2008-07-23 2020-07-28 Immudex Aps Combinatorial analysis and repair
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
US10369204B2 (en) 2008-10-02 2019-08-06 Dako Denmark A/S Molecular vaccines for infectious disease
AU2012354438B2 (en) * 2011-12-22 2016-03-31 GC Cell Corporation Method for producing natural killer cells, natural killer cells produced thereby, and composition for treating cancers and infectious diseases containing the same
KR101697473B1 (ko) 2014-11-26 2017-01-18 주식회사 녹십자랩셀 T 세포를 이용한 자연살해세포의 배양방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340565C (fr) * 1989-06-29 1999-05-25 Thomas B. Okarma Dispositif et methode pour capter et recuperer des cellules
EP1553168A3 (fr) * 1993-06-04 2011-04-06 The United States of America as represented by The Secretary of The Navy Procédé pour la stimulation sélective de la prolifération des cellules T

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005108554A1 (fr) * 2004-05-11 2005-11-17 Shukokai Incorporated Immunocyte adoptif pour vaccin antitumoral et similaire
US7655393B2 (en) 2004-05-11 2010-02-02 Shukokai Incorporated Adoptive immune cells for tumor vaccines
US8075882B2 (en) 2004-05-11 2011-12-13 Shukokai Incorporated Adoptive immune cells for tumor vaccines
JP2008120724A (ja) * 2006-11-10 2008-05-29 Japan Science & Technology Agency Th2型アレルギー性疾患治療薬及び感染症治療薬
JP2021058200A (ja) * 2015-05-13 2021-04-15 テルモ ビーシーティー、インコーポレーテッド 細胞の増殖
JP7101751B2 (ja) 2015-05-13 2022-07-15 テルモ ビーシーティー、インコーポレーテッド 細胞の増殖

Also Published As

Publication number Publication date
AU6649996A (en) 1997-02-26
EP0852618A1 (fr) 1998-07-15
CA2227327A1 (fr) 1997-02-13
WO1997005239A1 (fr) 1997-02-13

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