CA2227327A1 - Immunotherapie par cellules autologues: compositions cellulaires , methodes et application au traitement d'une maladie humaine - Google Patents
Immunotherapie par cellules autologues: compositions cellulaires , methodes et application au traitement d'une maladie humaine Download PDFInfo
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Classifications
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- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
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- A61K39/461—Cellular immunotherapy characterised by the cell type used
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- C12N2501/20—Cytokines; Chemokines
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/51—B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/515—CD3, T-cell receptor complex
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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Abstract
Compositions renfermant des populations essentiellement homogènes de cellules immunes définies par leur fonction ou leur phénotype, qui ont été isolées d'un patient puis développées et/ou différentiées ex vivo. L'invention porte également sur des méthodes de traitement ou de prévention d'une maladie ou de modification de l'état immunitaire du patient par réintroduction de telles cellules. L'invention porte enfin sur des méthodes de développement et/ou de différenciation de telles cellules ex vivo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50666895A | 1995-07-25 | 1995-07-25 | |
| US08/506,668 | 1995-07-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2227327A1 true CA2227327A1 (fr) | 1997-02-13 |
Family
ID=24015526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002227327A Abandoned CA2227327A1 (fr) | 1995-07-25 | 1996-07-24 | Immunotherapie par cellules autologues: compositions cellulaires , methodes et application au traitement d'une maladie humaine |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0852618A1 (fr) |
| JP (1) | JP2001520509A (fr) |
| AU (1) | AU6649996A (fr) |
| CA (1) | CA2227327A1 (fr) |
| WO (1) | WO1997005239A1 (fr) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1025123B1 (fr) * | 1997-10-23 | 2009-12-16 | Nikolaus W. Klehr | Procede pour la production de cytokines de sang autologue humain |
| JP2001522806A (ja) * | 1997-11-10 | 2001-11-20 | アーチ・デヴェロップメント・コーポレイション | エクス・ビボ活性化ｔ細胞を用いる腫瘍および腫瘍細胞の処理方法 |
| NZ508242A (en) * | 1998-04-24 | 2003-05-30 | Hemosol Inc | Efficient ex vivo expansion of CD4+ and CD8+ T-Cells from HIV infected subjects |
| AU765085B2 (en) | 1998-05-11 | 2003-09-11 | Miltenyi Biotec Gmbh | Method of direct selection of antigen-specific T cells |
| CA2335516A1 (fr) * | 1998-06-26 | 2000-01-06 | Keld Kaltoft | Methode de developpement et de selection des lymphocytes t associes a une pathologie |
| US6406699B1 (en) * | 1999-10-05 | 2002-06-18 | Gary W. Wood | Composition and method of cancer antigen immunotherapy |
| GB9928193D0 (en) * | 1999-11-29 | 2000-01-26 | Univ Bristol | Cell treatment method |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US20040241153A1 (en) * | 2001-08-31 | 2004-12-02 | Fowler Daniel H. | Methods of generating human cd4+ th1 cells |
| EP2070542A3 (fr) | 2001-08-15 | 2010-01-06 | Takara Bio Inc. | Procédé de culture étendue de lymphocytes T cyotoxiques spécifiques aux antigènes |
| US20030134415A1 (en) * | 2001-09-19 | 2003-07-17 | Gruenberg Micheal L. | Th1 cell adoptive immunotherapy |
| US20030175272A1 (en) * | 2002-03-07 | 2003-09-18 | Medcell Biologics, Inc. | Re-activated T-cells for adoptive immunotherapy |
| US20030170238A1 (en) * | 2002-03-07 | 2003-09-11 | Gruenberg Micheal L. | Re-activated T-cells for adoptive immunotherapy |
| CN100591760C (zh) | 2002-03-25 | 2010-02-24 | 宝生物工程株式会社 | 制备细胞毒性淋巴细胞的方法 |
| US20050084967A1 (en) | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| CA2497552C (fr) | 2002-09-06 | 2014-05-27 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Immunotherapie utilisant des lymphocytes specifiques d'un antigene selectionnes in vitro apres une chimiotherapie non myeloablative appau vrissant les lymphocytes |
| JP2006524991A (ja) | 2003-05-08 | 2006-11-09 | エクサイト セラピーズ インコーポレーティッド | 抗原特異的ｔ細胞の作製および単離の方法 |
| US7435592B2 (en) | 2003-05-13 | 2008-10-14 | Immunovative Therapies, Ltd. | Compositions for allogeneic cell therapy |
| US20070025961A1 (en) | 2003-06-03 | 2007-02-01 | Kenzo Bamba | Composition for stabilizing survival of transplanted hematopoietic stem cell, kit for obtaining the composition, method of stabilizing survival of transplanted hematopoietic stem cell, human monoclonal antibody or human polyclonal antibody and method of producing the same, gene encoding human monoclonal antibody and transf |
| WO2005007116A2 (fr) * | 2003-07-18 | 2005-01-27 | Valeocyte Therapies Llc | Systemes de cellules presentant l'antigene artificielles |
| US8927273B2 (en) | 2003-08-22 | 2015-01-06 | Takara Bio Inc. | Process for producing cytotoxic lymphocytes |
| WO2005108554A1 (fr) * | 2004-05-11 | 2005-11-17 | Shukokai Incorporated | Immunocyte adoptif pour vaccin antitumoral et similaire |
| US8765469B2 (en) | 2005-08-17 | 2014-07-01 | Takara Bio Inc. | Method of producing lymphocytes |
| JP4825113B2 (ja) * | 2006-11-10 | 2011-11-30 | 独立行政法人科学技術振興機構 | Ｔｈ２型アレルギー性疾患治療薬及び感染症治療薬 |
| EP2155782A2 (fr) | 2007-03-26 | 2010-02-24 | Dako Denmark A/S | Complexes peptidiques du cmh et leurs utilisations dans des maladies infectieuses |
| EP2167536A1 (fr) | 2007-07-03 | 2010-03-31 | Dako Denmark A/S | Procedes ameliores pour produire, marquer et utiliser des multimeres du cmh |
| WO2009039854A2 (fr) | 2007-09-27 | 2009-04-02 | Dako Denmark A/S | Multimères cmh dans le diagnostic, le vaccin et le traitement de la tuberculose |
| DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
| US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
| GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| US10369204B2 (en) | 2008-10-02 | 2019-08-06 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| EP2794859B1 (fr) * | 2011-12-22 | 2017-09-20 | Mogam Biotechnology Institute | Procédé pour produire des cellules tueuses naturelles, cellules tueuses naturelles produites de cette façon, et composition pour traiter des cancers et des maladies infectieuses contenant les mêmes |
| KR101697473B1 (ko) | 2014-11-26 | 2017-01-18 | 주식회사 녹십자랩셀 | T 세포를 이용한 자연살해세포의 배양방법 |
| JP6816026B2 (ja) * | 2015-05-13 | 2021-01-20 | テルモ ビーシーティー、インコーポレーテッド | 細胞の増殖 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340565C (fr) * | 1989-06-29 | 1999-05-25 | Thomas B. Okarma | Dispositif et methode pour capter et recuperer des cellules |
| PT700430E (pt) * | 1993-06-04 | 2005-07-29 | Univ Michigan | Processo para estimular selectivamente a proliferacao das celulas t |
-
1996
- 1996-07-24 CA CA002227327A patent/CA2227327A1/fr not_active Abandoned
- 1996-07-24 WO PCT/US1996/012170 patent/WO1997005239A1/fr not_active Application Discontinuation
- 1996-07-24 JP JP50770697A patent/JP2001520509A/ja not_active Ceased
- 1996-07-24 EP EP96926117A patent/EP0852618A1/fr not_active Withdrawn
- 1996-07-25 AU AU66499/96A patent/AU6649996A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6649996A (en) | 1997-02-26 |
| JP2001520509A (ja) | 2001-10-30 |
| EP0852618A1 (fr) | 1998-07-15 |
| WO1997005239A1 (fr) | 1997-02-13 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |