JP2001519642A - 肝炎gbvタンパクの翻訳の制御に有用な試薬および方法 - Google Patents

肝炎gbvタンパクの翻訳の制御に有用な試薬および方法

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Publication number
JP2001519642A
JP2001519642A JP50946397A JP50946397A JP2001519642A JP 2001519642 A JP2001519642 A JP 2001519642A JP 50946397 A JP50946397 A JP 50946397A JP 50946397 A JP50946397 A JP 50946397A JP 2001519642 A JP2001519642 A JP 2001519642A
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nucleic acid
gbv
sequence
hgbv
cat
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Japanese (ja)
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JP2001519642A5 (enExample
Inventor
サイモンズ,ジヨン・エヌ
デザイ,シユアーシユ・エム
マツシヤワー,アイザ・ケイ
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アボツト・ラボラトリーズ
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Priority claimed from US08/580,038 external-priority patent/US5807670A/en
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Publication of JP2001519642A5 publication Critical patent/JP2001519642A5/ja
Ceased legal-status Critical Current

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • C12Q1/707Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • C12N2310/315Phosphorothioates
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • C12N2310/318Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
    • C12N2310/3181Peptide nucleic acid, PNA
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    • C12N2310/33Chemical structure of the base
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    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays

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  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP50946397A 1995-08-14 1996-08-14 肝炎gbvタンパクの翻訳の制御に有用な試薬および方法 Ceased JP2001519642A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US226595P 1995-08-14 1995-08-14
US60/002,265 1995-08-14
US08/580,038 1995-12-21
US08/580,038 US5807670A (en) 1995-08-14 1995-12-21 Detection of hepatitis GB virus genotypes
US08/639,857 1996-04-19
US08/639,857 US5955318A (en) 1995-08-14 1996-04-19 Reagents and methods useful for controlling the translation of hepatitis GBV proteins
PCT/US1996/013198 WO1997007224A1 (en) 1995-08-14 1996-08-14 Reagents and methods useful for controlling the translation of hepatitis gbv proteins

Publications (2)

Publication Number Publication Date
JP2001519642A true JP2001519642A (ja) 2001-10-23
JP2001519642A5 JP2001519642A5 (enExample) 2004-08-26

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JP50946397A Ceased JP2001519642A (ja) 1995-08-14 1996-08-14 肝炎gbvタンパクの翻訳の制御に有用な試薬および方法

Country Status (5)

Country Link
US (1) US5955318A (enExample)
EP (1) EP0845042A1 (enExample)
JP (1) JP2001519642A (enExample)
CA (1) CA2229143A1 (enExample)
WO (1) WO1997007224A1 (enExample)

Cited By (1)

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WO2014084354A1 (ja) * 2012-11-29 2014-06-05 国立大学法人岐阜大学 Rna干渉剤、その製造方法及びその利用

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DE10002027A1 (de) * 2000-01-19 2001-07-26 Tenovis Gmbh & Co Kg Vorrichtung zur direkten Herstellung von Telekommunikationsverbindungen von einer TK-Anlage ins Mobilfunknetz
US20030224353A1 (en) * 2001-10-16 2003-12-04 Stein David A. Antisense antiviral agent and method for treating ssRNA viral infection
AU2002342057B2 (en) * 2001-10-16 2009-01-22 Avi Biopharma, Inc. Antisense antiviral agent and method for treating ssRNA viral infection
AU2002360417A1 (en) * 2001-11-26 2003-06-10 Duke University Genetically stable expression vector
CA2532795A1 (en) * 2003-08-07 2005-02-17 Avi Biopharma, Inc. Sense antiviral compound and method for treating ssrna viral infection
US20050222068A1 (en) * 2003-10-23 2005-10-06 Mourich Dan V Method and antisense composition for selective inhibition of HIV infection in hematopoietic cells
US8129352B2 (en) 2004-09-16 2012-03-06 Avi Biopharma, Inc. Antisense antiviral compound and method for treating ssRNA viral infection
US8357664B2 (en) 2004-10-26 2013-01-22 Avi Biopharma, Inc. Antisense antiviral compound and method for treating influenza viral infection
US7524829B2 (en) * 2004-11-01 2009-04-28 Avi Biopharma, Inc. Antisense antiviral compounds and methods for treating a filovirus infection
US20060240032A1 (en) * 2005-03-31 2006-10-26 Hinrichs David J Immunomodulating compositions and methods for use in the treatment of human autoimmune diseases
US8067571B2 (en) 2005-07-13 2011-11-29 Avi Biopharma, Inc. Antibacterial antisense oligonucleotide and method
WO2007030691A2 (en) * 2005-09-08 2007-03-15 Avi Biopharma, Inc. Antisense antiviral compound and method for treating picornavirus infection
AU2006287530A1 (en) * 2005-09-08 2007-03-15 Sarepta Therapeutics, Inc. Antisense antiviral compound and method for treating picornavirus infection
US8501704B2 (en) 2005-11-08 2013-08-06 Sarepta Therapeutics, Inc. Immunosuppression compound and treatment method
NZ571041A (en) * 2006-03-29 2011-04-29 Graphic Packaging Int Inc Carrier package which changes dimensions during loading
SI2735568T1 (en) * 2006-05-10 2018-01-31 Sarepta Therapeutics, Inc. Analogues of the oligonucleotide, with cationic links between subunits
US8785407B2 (en) * 2006-05-10 2014-07-22 Sarepta Therapeutics, Inc. Antisense antiviral agent and method for treating ssRNA viral infection
US20100035248A1 (en) * 2007-06-15 2010-02-11 Rastislav Levicky Surface-based nucleic acid assays employing morpholinos
WO2010080554A1 (en) 2008-12-17 2010-07-15 Avi Biopharma, Inc. Antisense compositions and methods for modulating contact hypersensitivity or contact dermatitis
CN102712928B (zh) 2009-11-13 2017-08-04 萨雷普塔治疗公司 反义抗病毒化合物及治疗流感病毒感染的方法
NZ603606A (en) 2010-05-28 2015-06-26 Sarepta Therapeutics Inc Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups
US8198429B2 (en) 2010-08-09 2012-06-12 Avi Biopharma, Inc. Antisense antiviral compounds and methods for treating a filovirus infection
WO2012031243A2 (en) 2010-09-03 2012-03-08 Avi Biopharma, Inc. dsRNA MOLECULES COMPRISING OLIGONUCLEOTIDE ANALOGS HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS
AU2012340390B2 (en) 2011-11-18 2016-11-24 Sarepta Therapeutics, Inc. Functionally-modified oligonucleotides and subunits thereof
US11020417B2 (en) 2015-06-04 2021-06-01 Sarepta Therapeutics, Inc Methods and compounds for treatment of lymphocyte-related diseases and conditions

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014084354A1 (ja) * 2012-11-29 2014-06-05 国立大学法人岐阜大学 Rna干渉剤、その製造方法及びその利用
JPWO2014084354A1 (ja) * 2012-11-29 2017-01-05 国立大学法人岐阜大学 Rna干渉剤、その製造方法及びその利用
US10006024B2 (en) 2012-11-29 2018-06-26 Gifu University RNA interference agent, method for producing same, and use therefor

Also Published As

Publication number Publication date
EP0845042A1 (en) 1998-06-03
CA2229143A1 (en) 1997-02-27
WO1997007224A1 (en) 1997-02-27
US5955318A (en) 1999-09-21

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