JP2001519441A - 新規ビタミンd受容体関連ポリペプチド、かかるポリペプチドをコードする核酸配列及びその使用 - Google Patents

新規ビタミンd受容体関連ポリペプチド、かかるポリペプチドをコードする核酸配列及びその使用

Info

Publication number
JP2001519441A
JP2001519441A JP2000515925A JP2000515925A JP2001519441A JP 2001519441 A JP2001519441 A JP 2001519441A JP 2000515925 A JP2000515925 A JP 2000515925A JP 2000515925 A JP2000515925 A JP 2000515925A JP 2001519441 A JP2001519441 A JP 2001519441A
Authority
JP
Japan
Prior art keywords
vdrr
polypeptide
nucleic acid
acid sequence
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000515925A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001519441A5 (enExample
Inventor
ベルチエンスタム,アンデシユ
ダールベリイ,マツツ
Original Assignee
ファルマシア・アクチエボラーグ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9703745A external-priority patent/SE9703745D0/xx
Application filed by ファルマシア・アクチエボラーグ filed Critical ファルマシア・アクチエボラーグ
Publication of JP2001519441A publication Critical patent/JP2001519441A/ja
Publication of JP2001519441A5 publication Critical patent/JP2001519441A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000515925A 1997-10-14 1998-08-31 新規ビタミンd受容体関連ポリペプチド、かかるポリペプチドをコードする核酸配列及びその使用 Pending JP2001519441A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE9703745-1 1997-10-14
SE9703745A SE9703745D0 (sv) 1997-10-14 1997-10-14 New receptors
SE9801148-9 1998-03-31
SE9801148A SE9801148D0 (sv) 1997-10-14 1998-03-31 New receptors
PCT/SE1998/001548 WO1999019354A1 (en) 1997-10-14 1998-08-31 Novel vitamin d receptor related polypeptides, nucleic acid sequence encoding the same and uses thereof

Publications (2)

Publication Number Publication Date
JP2001519441A true JP2001519441A (ja) 2001-10-23
JP2001519441A5 JP2001519441A5 (enExample) 2006-01-05

Family

ID=26663102

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000515925A Pending JP2001519441A (ja) 1997-10-14 1998-08-31 新規ビタミンd受容体関連ポリペプチド、かかるポリペプチドをコードする核酸配列及びその使用

Country Status (9)

Country Link
EP (1) EP1023323A1 (enExample)
JP (1) JP2001519441A (enExample)
KR (1) KR20010031120A (enExample)
CN (1) CN1134452C (enExample)
AU (1) AU732079B2 (enExample)
CA (1) CA2306453A1 (enExample)
NZ (1) NZ504025A (enExample)
SE (1) SE9801148D0 (enExample)
WO (1) WO1999019354A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007082550A (ja) * 1998-01-09 2007-04-05 Salk Inst For Biological Studies 新規なステロイド活性化核受容体とその利用法

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1044216A4 (en) * 1997-12-12 2001-10-31 Merck & Co Inc DNA MOLECULES ENCODING THE HUMAN CORE REPTOR PROTEINS nNR7 AND nNR7-1.
US6911537B2 (en) * 1998-01-09 2005-06-28 The Salk Institute For Biological Studies Xenobiotic compound modulated expression systems and uses therefor
AU2003200641B2 (en) * 1998-01-09 2008-04-03 The Salk Institute For Biological Studies Novel Steroid-activated Nuclear Receptors and Uses therefor
US6984773B1 (en) 1998-01-09 2006-01-10 The Salk Institute For Biological Studies Transgenic mice expressing a human SXR receptor polypeptide
US7238491B1 (en) 1998-03-27 2007-07-03 Smithkline Beecham Corporation Pregnane X receptor method
JP2002535241A (ja) * 1998-03-27 2002-10-22 グラクソ グループ リミテッド オーファン核内受容体
FR2801311B1 (fr) * 1999-11-22 2005-08-26 Centre Nat Rech Scient Polypeptides derives du recepteur nucleaire de la vitamine d, et leurs utilisations notamment dans le cadre du criblage d'analogues de la vitamine d
AU2006200258B2 (en) * 1999-12-09 2009-04-09 The Salk Institute For Biological Studies Novel steroid-activated nuclear receptors and uses therefor
US6514941B1 (en) 1999-12-10 2003-02-04 Campina Melkunie B.V. Method of preparing a casein hydrolysate enriched in anti-hypertensive peptides
US20040053866A1 (en) * 2002-08-21 2004-03-18 The Regents Of The University Of California Tumor suppressor genes and their uses
SE0400489D0 (sv) * 2004-02-27 2004-02-27 Biovitrum Ab Therapeutic proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989009223A1 (en) * 1988-03-30 1989-10-05 Arch Development Corporation Dna binding proteins including androgen receptor
DE69232537T2 (de) * 1991-09-17 2002-10-24 The Salk Institute For Biological Studies, La Jolla Rezeptoren der steroid/thyroid superfamilie von rezeptoren
US5756448A (en) * 1992-02-26 1998-05-26 The General Hospital Corporation Constitute activator of retinoid (CAR) receptor polypeptides
WO1996022390A1 (en) * 1995-01-17 1996-07-25 The Salk Institute For Biological Studies Methods, polypeptides, nucleotide sequence of xor-6, a vitamin d-like receptor from xenopus
AU5426596A (en) * 1995-05-16 1996-11-29 Salk Institute For Biological Studies, The Modulators for new members of the steroid/thyroid superfamily of receptors

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007082550A (ja) * 1998-01-09 2007-04-05 Salk Inst For Biological Studies 新規なステロイド活性化核受容体とその利用法
JP2010029211A (ja) * 1998-01-09 2010-02-12 Salk Inst For Biological Studies 新規なステロイド活性化核受容体とその利用法

Also Published As

Publication number Publication date
AU9013198A (en) 1999-05-03
WO1999019354A9 (en) 1999-12-02
SE9801148D0 (sv) 1998-03-31
AU732079B2 (en) 2001-04-12
CN1134452C (zh) 2004-01-14
WO1999019354A1 (en) 1999-04-22
CN1279689A (zh) 2001-01-10
CA2306453A1 (en) 1999-04-22
KR20010031120A (ko) 2001-04-16
NZ504025A (en) 2003-04-29
EP1023323A1 (en) 2000-08-02

Similar Documents

Publication Publication Date Title
Oberkofler et al. Potentiation of liver X receptor transcriptional activity by peroxisome-proliferator-activated receptor gamma co-activator 1alpha
JP2003535037A (ja) 炎症を治療する方法
JP2001519441A (ja) 新規ビタミンd受容体関連ポリペプチド、かかるポリペプチドをコードする核酸配列及びその使用
JP2002501083A (ja) リガンド受容体およびそれらの使用
JP2006068010A (ja) レチノイドx受容体相互作用性ポリペプチドならびに関連する分子および方法
DE69925271T2 (de) Angiostatin-bindendes protein
JP2002526098A (ja) 新規なぺプチド類
JP2000515018A (ja) メラトニン1aレセプター遺伝子調節領域およびその使用
AU1793092A (en) Receptors for bombesin-like peptides
JP2003520803A (ja) ホルモンレセプターの調節
US7118885B2 (en) Nucleic acid encoding vitamin D receptor related polypeptide
US5831051A (en) Receptor for peptide hormones involved in energy homeostasis, and method and compositions for use thereof
JPWO1999000491A1 (ja) 新規なレポーター遺伝子dnaを含むプラスミドdnaおよびその用途
JP3759899B2 (ja) 新規ヒトアンドロゲンレセプター変異体
US20030215878A1 (en) Novel G protein-coupled purinergic receptor, GAVE17
MXPA00003667A (en) Novel vitamin d receptor related polypeptides, nucleic acid sequence encoding the same and uses thereof
US6989242B1 (en) Car receptors and related molecules and methods
US20030211577A1 (en) Novel G protein-coupled receptor, GAVE7
US20040234993A1 (en) Novel g protein-coupled receptor, gave 10
RUDOLPH GABA A Receptor
JP2005500036A (ja) 新規のgタンパク質共役受容体、gave3
ZA200400383B (en) A novel G protein-coupled receptor, GAVE8.
JPWO2000039315A1 (ja) Ucp−2プロモーターおよびその用途
AU2003226272A8 (en) A novel g protein-coupled purinergic receptor, gave 17
AU2002344837A1 (en) A novel G protein-coupled receptor, GAVE 3

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050701

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050701

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20050621

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080520

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20081014