JP2001513526A - アントラニル酸類似体 - Google Patents

アントラニル酸類似体

Info

Publication number
JP2001513526A
JP2001513526A JP2000507205A JP2000507205A JP2001513526A JP 2001513526 A JP2001513526 A JP 2001513526A JP 2000507205 A JP2000507205 A JP 2000507205A JP 2000507205 A JP2000507205 A JP 2000507205A JP 2001513526 A JP2001513526 A JP 2001513526A
Authority
JP
Japan
Prior art keywords
phenyl
acryloylamino
benzoic acid
hydrogen
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000507205A
Other languages
English (en)
Japanese (ja)
Inventor
ジョゼフ・リチャード・レノックス
スカイラー・アダム・アンテイン
ジョン・アンソニー・ブテラ
Original Assignee
アメリカン・ホーム・プロダクツ・コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アメリカン・ホーム・プロダクツ・コーポレイション filed Critical アメリカン・ホーム・プロダクツ・コーポレイション
Publication of JP2001513526A publication Critical patent/JP2001513526A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/06—Anti-spasmodics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
JP2000507205A 1997-08-05 1998-08-03 アントラニル酸類似体 Pending JP2001513526A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90668397A 1997-08-05 1997-08-05
US08/906,683 1997-08-05
PCT/US1998/016099 WO1999007669A1 (en) 1997-08-05 1998-08-03 Anthranilic acid analogs

Publications (1)

Publication Number Publication Date
JP2001513526A true JP2001513526A (ja) 2001-09-04

Family

ID=25422806

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000507205A Pending JP2001513526A (ja) 1997-08-05 1998-08-03 アントラニル酸類似体

Country Status (7)

Country Link
EP (1) EP1003712A1 (pt)
JP (1) JP2001513526A (pt)
CN (1) CN1273579A (pt)
AU (1) AU8684598A (pt)
BR (1) BR9811845A (pt)
CA (1) CA2297412A1 (pt)
WO (1) WO1999007669A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003503385A (ja) * 1999-06-25 2003-01-28 アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング インダニル置換ベンゼンカルボキサミド、その製造方法、薬剤としてのその使用およびそれを含有する医薬処方物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19935219A1 (de) * 1999-07-27 2001-02-01 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
PE20020354A1 (es) 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
DE10065042A1 (de) * 2000-12-23 2002-06-27 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
US7429593B2 (en) 2001-09-14 2008-09-30 Shionogi & Co., Ltd. Utilities of amide compounds
AU2003258491A1 (en) * 2002-09-05 2004-03-29 Neurosearch A/S Amide derivatives and their use as chloride channel blockers
WO2004047738A2 (en) * 2002-11-22 2004-06-10 Bristol-Myers Squibb Company Arylcyclopropylcarboxylic amides as potassium channel openers
GB0319124D0 (en) * 2003-08-14 2003-09-17 Smithkline Beecham Corp Chemical compounds
CN110357789B (zh) * 2018-04-11 2022-09-30 华东理工大学 作为dhodh抑制剂的n-取代丙烯酰胺衍生物及其制备和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5970654A (ja) * 1982-10-15 1984-04-21 Nippon Redarii Kk アントラニル酸誘導体
JPS6097946A (ja) * 1983-11-01 1985-05-31 Ono Pharmaceut Co Ltd カルボキサミド誘導体
GB9214120D0 (en) * 1991-07-25 1992-08-12 Ici Plc Therapeutic amides
DK41193D0 (da) * 1993-04-07 1993-04-07 Neurosearch As Ionkanalaabnere

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003503385A (ja) * 1999-06-25 2003-01-28 アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング インダニル置換ベンゼンカルボキサミド、その製造方法、薬剤としてのその使用およびそれを含有する医薬処方物

Also Published As

Publication number Publication date
CN1273579A (zh) 2000-11-15
EP1003712A1 (en) 2000-05-31
WO1999007669A1 (en) 1999-02-18
AU8684598A (en) 1999-03-01
CA2297412A1 (en) 1999-02-18
BR9811845A (pt) 2000-08-08

Similar Documents

Publication Publication Date Title
US6046239A (en) Anthranilic acid analogs
US6127392A (en) Anthranilic acid analogs
US6096770A (en) Anthranilic acid analogs
KR100522011B1 (ko) 설폰아미드 및 카르복사미드 유도체와, 이들을 유효 성분으로 함유하는 약제
CA2606471C (en) Benzisoxazole piperidine compounds and methods of use thereof
TWI409247B (zh) ４-取代之苯氧基苯基乙酸衍生物
JPH08508034A (ja) フェノキシフェニル酢酸誘導体
JP2004196702A (ja) 新規なアミド誘導体又はその塩
JPWO2008123207A1 (ja) オルニチン誘導体
JPH10310575A (ja) 新規なキノリンスルフィド誘導体、その製造方法及び用途
JP2001513526A (ja) アントラニル酸類似体
DE4327365A1 (de) Verwendung von Phenolen und Phenolderivaten als Arzneimittel mit fibrinogensenkender Wirkung
CA2419722A1 (en) Benzoic acid derivatives and drugs containing the same as the active ingredient
WO2003018515A2 (en) Prime ring substituted thyroid receptor antagonists for the treatment of cardiac and metabolic disorders
AU2002331145A1 (en) Prime ring substituted thyroid receptor antagonists for the treatment of cardiac and metabolic disorders
JP2007523873A (ja) 新規化合物
JP2001501179A (ja) キヌレニン―３―ヒドロキシラーゼ抑制活性を有するｎ―置換―２―アミノ―４―フェニル―４―オキソ―ブタン酸
JP2603639B2 (ja) チアゾリジン―４―カルボン酸化合物、その製造方法、この化合物を含有する解熱消炎鎮痛剤および虚血・リパーフュージョン症候群治療薬
JP2001513527A (ja) アントラニル酸類似体
TW201819361A (zh) 新穎吲唑化合物
MXPA00001261A (en) Anthranilic acid analogs
PT88116B (pt) Processo de preparacao de derivados de acido naftalenopropionico uteis como agentes anti-inflamatorios/antialergicos
AU727217B2 (en) Heterocyclylmethylamino derivatives of cyclobutene-3,4- diones as potassium channel modulators
JP2008506680A (ja) ピラゾリン誘導体、それを得るための方法および治療薬としてのその使用
MXPA00001255A (en) Anthranilic acid analogs