JP2001513109A - 核酸含有重合可能錯体 - Google Patents
核酸含有重合可能錯体Info
- Publication number
- JP2001513109A JP2001513109A JP53854698A JP53854698A JP2001513109A JP 2001513109 A JP2001513109 A JP 2001513109A JP 53854698 A JP53854698 A JP 53854698A JP 53854698 A JP53854698 A JP 53854698A JP 2001513109 A JP2001513109 A JP 2001513109A
- Authority
- JP
- Japan
- Prior art keywords
- polymerizable
- ethylene
- nucleic acid
- polymerization
- containing monomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/812,105 US5932711A (en) | 1997-03-05 | 1997-03-05 | Nucleic acid-containing polymerizable complex |
| US08/812,105 | 1997-03-05 | ||
| PCT/US1998/003246 WO1998039351A1 (en) | 1997-03-05 | 1998-02-20 | Nucleic acid-containing polymerizable complex |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001513109A true JP2001513109A (ja) | 2001-08-28 |
| JP2001513109A5 JP2001513109A5 (enExample) | 2005-10-06 |
Family
ID=25208519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53854698A Ceased JP2001513109A (ja) | 1997-03-05 | 1998-02-20 | 核酸含有重合可能錯体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5932711A (enExample) |
| EP (1) | EP0971943B1 (enExample) |
| JP (1) | JP2001513109A (enExample) |
| AT (1) | ATE449781T1 (enExample) |
| AU (1) | AU6436498A (enExample) |
| CA (1) | CA2283798A1 (enExample) |
| DE (1) | DE69841304D1 (enExample) |
| WO (1) | WO1998039351A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005200405A (ja) * | 2003-12-02 | 2005-07-28 | F Hoffmann La Roche Ag | 分子ロッドを含むオリゴヌクレオチド |
| JP2007514643A (ja) * | 2003-09-18 | 2007-06-07 | アイシス ファーマシューティカルズ、インク． | ４’−チオヌクレオシドおよびオリゴマー化合物 |
| JP2007525571A (ja) * | 2004-01-07 | 2007-09-06 | ソレクサ リミテッド | 修飾分子アレイ |
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| US20020150921A1 (en) * | 1996-02-09 | 2002-10-17 | Francis Barany | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| US6852487B1 (en) * | 1996-02-09 | 2005-02-08 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| EP0912761A4 (en) * | 1996-05-29 | 2004-06-09 | Cornell Res Foundation Inc | DETERMINATION OF DIFFERENCES IN THE NUCLEIC ACID SEQUENCE BY MEANS OF A COMBINATION OF LIGASE DETERMINATION AND POLYMERASE CHAIN REACTION |
| WO1998051823A1 (en) * | 1997-05-16 | 1998-11-19 | Mosaic Technologies | Electrophoretic analysis of molecules using immobilized probes |
| CA2331767A1 (en) | 1998-06-18 | 1999-12-23 | Mosaic Technologies | Denaturing gradient affinity electrophoresis and methods of use thereof |
| JP2002518026A (ja) * | 1998-06-19 | 2002-06-25 | エムティー テクノロジー， インコーポレイテッド | Ｓｒｐｒｎａを用いる非ウイルス生物の検出 |
| US6238927B1 (en) * | 1998-10-05 | 2001-05-29 | Mosaic Technologies, Incorporated | Reverse displacement assay for detection of nucleic acid sequences |
| AU1817300A (en) * | 1998-11-13 | 2000-06-05 | Mosaic Technologies | Multielement analytical device for assay of nucleic acid sequences and uses therefore |
| EP1155056A4 (en) * | 1998-12-04 | 2004-05-12 | Mosaic Technologies Inc | METHOD OF IMMOBILIZING OLIGONUCLEOTIDES |
| US20050153926A1 (en) * | 1998-12-04 | 2005-07-14 | Adams Christopher P. | Method for the immobilization of oligonucleotides |
| US6441152B1 (en) | 1998-12-08 | 2002-08-27 | Boston Probes, Inc. | Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices |
| CA2369083A1 (en) * | 1999-02-26 | 2000-08-31 | Mosaic Technologies | Biochemical purification devices with immobilized capture probes and their uses |
| CA2371727A1 (en) * | 1999-04-02 | 2000-10-12 | Mosaic Technologies | Electrophoretic analysis of target molecules using adapter molecules |
| US6921638B2 (en) * | 1999-06-25 | 2005-07-26 | Amersham Biosciences Ab | Hydrogel-based microarray signal amplification methods and devices therefor |
| US6664061B2 (en) | 1999-06-25 | 2003-12-16 | Amersham Biosciences Ab | Use and evaluation of a [2+2] photoaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix |
| US6372813B1 (en) | 1999-06-25 | 2002-04-16 | Motorola | Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays |
| CA2377739A1 (en) | 1999-07-02 | 2001-01-11 | Symyx Technologies, Inc. | Polymer brushes for immobilizing molecules to a surface or substrate, where the polymers have water-soluble or water-dispersible segments and probes bonded thereto |
| RU2157385C1 (ru) * | 1999-07-19 | 2000-10-10 | Институт молекулярной биологии им. В.А. Энгельгардта РАН | Способ изготовления микрочипов на основе олигонуклеотидов |
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| RU2175972C2 (ru) * | 1999-12-28 | 2001-11-20 | Институт молекулярной биологии им. В.А. Энгельгардта РАН | Способ иммобилизации олигонуклеотидов, содержащих непредельные группы, в полимерных гидрогелях при формировании микрочипа |
| US20030138774A1 (en) * | 2000-01-19 | 2003-07-24 | Jones Chris L. | Methods and apparatus for separating and detecting nucleic acid |
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| AU2001247414A1 (en) | 2000-03-14 | 2001-09-24 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
| US6962906B2 (en) * | 2000-03-14 | 2005-11-08 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
| EP1303639A2 (en) | 2000-04-14 | 2003-04-23 | Cornell Research Foundation, Inc. | Method of designing addressable array for detection of nucleic acid sequence differences using ligase detection reaction |
| RU2278612C2 (ru) * | 2000-07-14 | 2006-06-27 | Лайфскен, Инк. | Иммуносенсор |
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| US6656725B2 (en) * | 2001-08-15 | 2003-12-02 | The University Of Chicago | Method of fabrication of microarray of gel-immobilized compounds on a chip by copolymerization |
| RU2216547C2 (ru) * | 2001-10-16 | 2003-11-20 | Институт молекулярной биологии им. В.А. Энгельгардта РАН | Способ полимеризационной иммобилизации биологических макромолекул и композиция для его осуществления |
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| US8809071B2 (en) | 2002-11-29 | 2014-08-19 | Marcella Chiari | Method for immobilizing biologic molecules on solid surfaces |
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| US7785769B2 (en) * | 2003-07-25 | 2010-08-31 | The United States of America as reprsented by the Secretary of the Navy | Immobilization of oligonucleotides and proteins in sugar-containing hydrogels |
| US20050136536A1 (en) * | 2003-09-15 | 2005-06-23 | Anderson Daniel G. | Embryonic epithelial cells |
| JP2007512509A (ja) * | 2003-11-05 | 2007-05-17 | エグザクト サイエンシーズ コーポレイション | 反復的親和性分離およびその使用 |
| DE102004062281A1 (de) * | 2003-12-29 | 2005-07-28 | Siemens Ag | Verfahren und Spotting-Lösung zum Herstellen von Microarrays |
| US7547775B2 (en) * | 2004-12-31 | 2009-06-16 | Affymetrix, Inc. | Parallel preparation of high fidelity probes in an array format |
| US7749701B2 (en) * | 2005-08-11 | 2010-07-06 | Agilent Technologies, Inc. | Controlling use of oligonucleotide sequences released from arrays |
| US8658608B2 (en) * | 2005-11-23 | 2014-02-25 | Yale University | Modified triple-helix forming oligonucleotides for targeted mutagenesis |
| RU2394915C2 (ru) * | 2006-03-24 | 2010-07-20 | Александр Борисович Четверин | Бесконтактные способы обнаружения молекулярных колоний, наборы реагентов и устройство для их осуществления |
| JP2010515464A (ja) * | 2007-01-11 | 2010-05-13 | イエール・ユニバーシテイ | Ｈｉｖ細胞表面受容体の標的化不活性化のための組成物および方法 |
| WO2008130263A1 (fr) | 2007-04-20 | 2008-10-30 | Institut Molekulyarnoi Biologii Im V.A. Engeldardta Rossiskoi Akademii Nauk | Monomère et composition destinés à la réception d'hydrogel à faible pourcentage et/ou de l'hydrogel possédant une faible quantité de réticulations transversales, hydrogel et la biopuce basés sur cet hydrogel |
| EP2435461B1 (en) | 2009-05-29 | 2017-08-09 | Life Technologies Corporation | Scaffolded nucleic acid polymer particles and methods of making and using |
| WO2013006824A2 (en) | 2011-07-07 | 2013-01-10 | Life Technologies Corporation | Polymer particles, nucleic acid polymer particles and methods of making and using the same |
| JP2015513666A (ja) | 2012-02-17 | 2015-05-14 | エヌブイエス テクノロジーズ，インコーポレイティド | アッセイへの適用のためのポリマー骨格 |
| US20140106979A1 (en) | 2012-10-12 | 2014-04-17 | NVS Technologies, Inc. | Polymers having orthogonal reactive groups and uses thereof |
| CN105189583A (zh) | 2013-03-14 | 2015-12-23 | Nvs技术股份有限公司 | 螯合生物分子的表面氧化及相关方法 |
| CN105658817B (zh) | 2013-09-13 | 2025-01-03 | 生命技术公司 | 使用凝聚核酸颗粒的装置制备 |
| AU2017221405A1 (en) | 2016-02-16 | 2018-09-20 | Carnegie Mellon University | Compositions for enhancing targeted gene editing and methods of use thereof |
| WO2018187493A1 (en) | 2017-04-04 | 2018-10-11 | Yale University | Compositions and methods for in utero delivery |
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| DE2003266A1 (de) * | 1970-01-26 | 1971-08-05 | Waldhof Zellstoff Fab | Verfahren zur Herstellung von Gelen |
| IL99862A (en) * | 1990-10-26 | 1995-06-29 | Genta Inc | Non-aromatic polymeric reactants for solid phase synthesis of oligomers |
| DK51092D0 (da) * | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
| FR2679255B1 (fr) * | 1991-07-17 | 1993-10-22 | Bio Merieux | Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation. |
| US5495006A (en) * | 1991-09-27 | 1996-02-27 | Allelix Biopharmaceuticals, Inc. | Antiviral polynucleotide conjugates |
| DE4322884A1 (de) * | 1992-10-09 | 1994-04-14 | Bayer Ag | Biologisch aktive Polymere |
| JPH06121698A (ja) * | 1992-10-12 | 1994-05-06 | Canon Inc | Ｄｎａプローブ用モノマー、ｄｎａプローブ、及びその製造方法 |
-
1997
- 1997-03-05 US US08/812,105 patent/US5932711A/en not_active Expired - Lifetime
-
1998
- 1998-02-20 EP EP98910016A patent/EP0971943B1/en not_active Expired - Lifetime
- 1998-02-20 AT AT98910016T patent/ATE449781T1/de not_active IP Right Cessation
- 1998-02-20 CA CA002283798A patent/CA2283798A1/en not_active Abandoned
- 1998-02-20 DE DE69841304T patent/DE69841304D1/de not_active Expired - Lifetime
- 1998-02-20 JP JP53854698A patent/JP2001513109A/ja not_active Ceased
- 1998-02-20 WO PCT/US1998/003246 patent/WO1998039351A1/en not_active Ceased
- 1998-02-20 AU AU64364/98A patent/AU6436498A/en not_active Abandoned
- 1998-10-30 US US09/183,092 patent/US6180770B1/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007514643A (ja) * | 2003-09-18 | 2007-06-07 | アイシス ファーマシューティカルズ、インク． | ４’−チオヌクレオシドおよびオリゴマー化合物 |
| JP2005200405A (ja) * | 2003-12-02 | 2005-07-28 | F Hoffmann La Roche Ag | 分子ロッドを含むオリゴヌクレオチド |
| JP2007525571A (ja) * | 2004-01-07 | 2007-09-06 | ソレクサ リミテッド | 修飾分子アレイ |
Also Published As
| Publication number | Publication date |
|---|---|
| DE69841304D1 (de) | 2010-01-07 |
| ATE449781T1 (de) | 2009-12-15 |
| US5932711A (en) | 1999-08-03 |
| CA2283798A1 (en) | 1998-09-11 |
| EP0971943B1 (en) | 2009-11-25 |
| EP0971943A4 (en) | 2001-03-14 |
| WO1998039351A1 (en) | 1998-09-11 |
| US6180770B1 (en) | 2001-01-30 |
| EP0971943A1 (en) | 2000-01-19 |
| AU6436498A (en) | 1998-09-22 |
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