JP2001513106A - グルココルチコイドと局所麻酔剤との相乗的な併用による好酸球関連病態、例えば気管支喘息の治療 - Google Patents

グルココルチコイドと局所麻酔剤との相乗的な併用による好酸球関連病態、例えば気管支喘息の治療

Info

Publication number
JP2001513106A
JP2001513106A JP53770098A JP53770098A JP2001513106A JP 2001513106 A JP2001513106 A JP 2001513106A JP 53770098 A JP53770098 A JP 53770098A JP 53770098 A JP53770098 A JP 53770098A JP 2001513106 A JP2001513106 A JP 2001513106A
Authority
JP
Japan
Prior art keywords
local anesthetic
use according
alkyl
eosinophil
glucocorticoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP53770098A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001513106A5 (https=
Inventor
ジェイ． グレイク，ジェラルド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayo Foundation for Medical Education and Research
Original Assignee
Mayo Clinic in Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Clinic in Florida filed Critical Mayo Clinic in Florida
Publication of JP2001513106A publication Critical patent/JP2001513106A/ja
Publication of JP2001513106A5 publication Critical patent/JP2001513106A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP53770098A 1997-02-26 1998-02-26 グルココルチコイドと局所麻酔剤との相乗的な併用による好酸球関連病態、例えば気管支喘息の治療 Ceased JP2001513106A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/805,623 US5837713A (en) 1997-02-26 1997-02-26 Treatment of eosinophil-associated pathologies by administration of topical anesthetics and glucocorticoids
US08/805,623 1997-02-26
PCT/US1998/002960 WO1998037896A1 (en) 1997-02-26 1998-02-26 Treatment of eosinophil-associated pathologies, such as bronchial asthma, with synergistic combinations of glucocorticoids and a local anesthetics

Publications (2)

Publication Number Publication Date
JP2001513106A true JP2001513106A (ja) 2001-08-28
JP2001513106A5 JP2001513106A5 (https=) 2005-10-06

Family

ID=25192051

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53770098A Ceased JP2001513106A (ja) 1997-02-26 1998-02-26 グルココルチコイドと局所麻酔剤との相乗的な併用による好酸球関連病態、例えば気管支喘息の治療

Country Status (6)

Country Link
US (1) US5837713A (https=)
EP (1) EP0979085A1 (https=)
JP (1) JP2001513106A (https=)
AU (1) AU6327498A (https=)
CA (1) CA2282639A1 (https=)
WO (1) WO1998037896A1 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006126581A1 (ja) * 2005-04-28 2006-11-30 Dainippon Sumitomo Pharma Co., Ltd. 組合せ医薬
JP2007518817A (ja) * 2004-01-21 2007-07-12 シェーリング　コーポレイション 処置方法
JP2008501726A (ja) * 2004-06-07 2008-01-24 ファンダカオ オスワルド クルズ−フィオクルズ リドカインから誘導される化合物、薬学的組成物、使用法、および疾患の治療、予防または抑制の方法
JP4865792B2 (ja) * 2005-07-12 2012-02-01 赴朝 李 局所麻酔薬の効果増強・時間延長剤
JP2012532887A (ja) * 2009-07-10 2012-12-20 プレジデント アンド フェロウズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
US11021443B2 (en) 2015-08-03 2021-06-01 President And Fellows Of Harvard College Charged ion channel blockers and methods for use

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US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
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AU2002316053A1 (en) 2001-05-01 2002-11-11 A.V. Topchiev Institute Of Petrochemical Synthesis Two-phase, water-absorbent bioadhesive composition
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
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US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
US7452523B2 (en) * 2004-01-27 2008-11-18 Gilead Sciences, Inc. Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough and tussive attacks
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JP2008513445A (ja) * 2004-09-20 2008-05-01 コラス ファーマ インコーポレイテッド 吸入による送達で治療効果のある薬剤の許容性の改善方法
AU2005310312A1 (en) * 2004-09-20 2006-06-08 Corus Pharma, Inc. A method for improvement of tolerance for therapeutically effective agents delivered by inhalation
US20060134008A1 (en) * 2004-12-16 2006-06-22 Daniel Deaver Compositions and methods for pulmonary conditions
US8277780B2 (en) * 2005-05-27 2012-10-02 Taro Pharmaceutical North America, Inc. Stable liquid desoximethasone compositions with reduced oxidized impurity
WO2007056457A2 (en) * 2005-11-09 2007-05-18 Combinatorx, Incorporated Methods, compositions, and kits for the treatment of medical conditions
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US20070249572A1 (en) * 2005-12-20 2007-10-25 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
US20070197486A1 (en) * 2005-12-20 2007-08-23 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids
US20070160542A1 (en) * 2005-12-20 2007-07-12 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070178049A1 (en) * 2005-12-20 2007-08-02 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070185066A1 (en) * 2005-12-20 2007-08-09 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
JP2009526858A (ja) * 2006-02-15 2009-07-23 ティカ レーケメデル アーベー コルチコステロイド溶液を製造する方法
AU2007322033B2 (en) 2006-11-20 2013-07-11 President And Fellows Of Harvard College Methods, compositions, and kits for treating pain and pruritis
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US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
US20090143343A1 (en) * 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007518817A (ja) * 2004-01-21 2007-07-12 シェーリング　コーポレイション 処置方法
JP2008110991A (ja) * 2004-01-21 2008-05-15 Schering Corp 処置方法
JP2008501726A (ja) * 2004-06-07 2008-01-24 ファンダカオ オスワルド クルズ−フィオクルズ リドカインから誘導される化合物、薬学的組成物、使用法、および疾患の治療、予防または抑制の方法
WO2006126581A1 (ja) * 2005-04-28 2006-11-30 Dainippon Sumitomo Pharma Co., Ltd. 組合せ医薬
JP4865792B2 (ja) * 2005-07-12 2012-02-01 赴朝 李 局所麻酔薬の効果増強・時間延長剤
JP2012532887A (ja) * 2009-07-10 2012-12-20 プレジデント アンド フェロウズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
JP2017178948A (ja) * 2009-07-10 2017-10-05 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
US10729664B2 (en) 2009-07-10 2020-08-04 President And Fellows Of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
US11021443B2 (en) 2015-08-03 2021-06-01 President And Fellows Of Harvard College Charged ion channel blockers and methods for use

Also Published As

Publication number Publication date
AU6327498A (en) 1998-09-18
WO1998037896A1 (en) 1998-09-03
CA2282639A1 (en) 1998-09-03
EP0979085A1 (en) 2000-02-16
US5837713A (en) 1998-11-17

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