JP2001511042A5 - - Google Patents

Download PDF

Info

Publication number
JP2001511042A5
JP2001511042A5 JP1998534870A JP53487098A JP2001511042A5 JP 2001511042 A5 JP2001511042 A5 JP 2001511042A5 JP 1998534870 A JP1998534870 A JP 1998534870A JP 53487098 A JP53487098 A JP 53487098A JP 2001511042 A5 JP2001511042 A5 JP 2001511042A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998534870A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001511042A (ja
JP4388602B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/002159 external-priority patent/WO1998034655A1/en
Publication of JP2001511042A publication Critical patent/JP2001511042A/ja
Publication of JP2001511042A5 publication Critical patent/JP2001511042A5/ja
Application granted granted Critical
Publication of JP4388602B2 publication Critical patent/JP4388602B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP53487098A 1997-02-07 1998-02-05 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法 Expired - Fee Related JP4388602B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3732797P 1997-02-07 1997-02-07
US60/037,327 1997-02-07
US4790997P 1997-05-29 1997-05-29
US60/047,909 1997-05-29
PCT/US1998/002159 WO1998034655A1 (en) 1997-02-07 1998-02-05 Matrix-free osteogenic devices, implants and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009011457A Division JP5124495B2 (ja) 1997-02-07 2009-01-21 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法

Publications (3)

Publication Number Publication Date
JP2001511042A JP2001511042A (ja) 2001-08-07
JP2001511042A5 true JP2001511042A5 (enExample) 2005-10-06
JP4388602B2 JP4388602B2 (ja) 2009-12-24

Family

ID=26714038

Family Applications (4)

Application Number Title Priority Date Filing Date
JP53487098A Expired - Fee Related JP4388602B2 (ja) 1997-02-07 1998-02-05 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法
JP2009011457A Expired - Fee Related JP5124495B2 (ja) 1997-02-07 2009-01-21 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法
JP2012025783A Withdrawn JP2012102145A (ja) 1997-02-07 2012-02-09 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法
JP2015155698A Pending JP2015227366A (ja) 1997-02-07 2015-08-06 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2009011457A Expired - Fee Related JP5124495B2 (ja) 1997-02-07 2009-01-21 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法
JP2012025783A Withdrawn JP2012102145A (ja) 1997-02-07 2012-02-09 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法
JP2015155698A Pending JP2015227366A (ja) 1997-02-07 2015-08-06 マトリクスを含まない骨形成デバイス、移植片、およびその使用方法

Country Status (8)

Country Link
US (2) US6281195B1 (enExample)
EP (3) EP0957943B2 (enExample)
JP (4) JP4388602B2 (enExample)
AT (1) ATE239514T1 (enExample)
AU (1) AU6267798A (enExample)
CA (1) CA2280931C (enExample)
DE (1) DE69814352T3 (enExample)
WO (1) WO1998034655A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7763270B2 (en) 2002-09-10 2010-07-27 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein
US8546334B2 (en) 2001-11-19 2013-10-01 Scil Technology Gmbh Device having osteoinductive and osteoconductive properties

Families Citing this family (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070166353A1 (en) * 1988-04-08 2007-07-19 Stryker Corporation Osteogenic proteins
US6919308B2 (en) * 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
EP1221484A3 (en) * 1988-04-08 2002-09-18 Stryker Corporation Biosynthetic osteogenic proteins and osteogenic devices containing them
US6586388B2 (en) * 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US7056882B2 (en) * 1991-03-11 2006-06-06 Curis, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US6077823A (en) * 1991-03-11 2000-06-20 Creative Biomolecules, Inc. Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
US6495513B1 (en) * 1991-03-11 2002-12-17 Curis, Inc. Morphogen-enhanced survival and repair of neural cells
US20080233170A1 (en) * 1992-02-21 2008-09-25 Stryker Corporation Osteogenic Proteins
US6221854B1 (en) 1996-03-05 2001-04-24 Orquest, Inc. Method of promoting bone growth with hyaluronic acid and growth factors
US8556983B2 (en) 2001-05-25 2013-10-15 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US8771365B2 (en) 2009-02-25 2014-07-08 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs, and related tools
US9603711B2 (en) 2001-05-25 2017-03-28 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US20030055502A1 (en) 2001-05-25 2003-03-20 Philipp Lang Methods and compositions for articular resurfacing
US8735773B2 (en) 2007-02-14 2014-05-27 Conformis, Inc. Implant device and method for manufacture
US8083745B2 (en) 2001-05-25 2011-12-27 Conformis, Inc. Surgical tools for arthroplasty
US7534263B2 (en) 2001-05-25 2009-05-19 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US7468075B2 (en) 2001-05-25 2008-12-23 Conformis, Inc. Methods and compositions for articular repair
US8617242B2 (en) 2001-05-25 2013-12-31 Conformis, Inc. Implant device and method for manufacture
US7618451B2 (en) 2001-05-25 2009-11-17 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
US8545569B2 (en) 2001-05-25 2013-10-01 Conformis, Inc. Patient selectable knee arthroplasty devices
US8882847B2 (en) 2001-05-25 2014-11-11 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US8480754B2 (en) 2001-05-25 2013-07-09 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
DE69814352T3 (de) * 1997-02-07 2009-08-13 Stryker Corp., Kalamazoo Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung
EP1037910A2 (en) * 1997-12-04 2000-09-27 Curis, Inc. Maintenance of smooth muscle integrity by morphogenic proteins
DE69941304D1 (de) 1998-09-14 2009-10-01 Univ R Zustandsbestimmung eines gelenks und schadenvorsorge
US7239908B1 (en) 1998-09-14 2007-07-03 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
US7067144B2 (en) * 1998-10-20 2006-06-27 Omeros Corporation Compositions and methods for systemic inhibition of cartilage degradation
JP3786533B2 (ja) * 1998-11-12 2006-06-14 善彦 西村 ペプチド及び骨形成促進剤
EP1135154B1 (en) * 1998-12-01 2003-05-07 Akzo Nobel N.V. Improvement of folliculogenesis
WO2000045870A1 (en) * 1999-02-04 2000-08-10 Sdgi Holdings, Inc. Osteogenic paste compositions and uses thereof
PT1223990E (pt) * 1999-10-15 2004-12-31 Fidia Advanced Biopolymers Srl Formulacoes de acido hialuronico para administracao de proteinas osteogenicas
AU2001290888B8 (en) 2000-09-14 2007-07-26 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
CA2425089A1 (en) 2000-09-14 2002-03-21 Philipp Lang Assessing condition of a joint and cartilage loss
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US8951260B2 (en) 2001-05-25 2015-02-10 Conformis, Inc. Surgical cutting guide
US20070083266A1 (en) 2001-05-25 2007-04-12 Vertegen, Inc. Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints
US8439926B2 (en) 2001-05-25 2013-05-14 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US9308091B2 (en) 2001-05-25 2016-04-12 Conformis, Inc. Devices and methods for treatment of facet and other joints
US7132110B2 (en) * 2001-08-30 2006-11-07 Isotis Orthobiologics, Inc. Tissue repair compositions and methods for their manufacture and use
AU2002365969A1 (en) * 2001-11-20 2003-06-10 Scott Bruder Flowable osteogenic and chondrogenic compositions
US7205337B2 (en) * 2001-12-21 2007-04-17 Isotis Orthobiologics, Inc. End-capped polymers and compositions containing such compounds
AU2002357898A1 (en) * 2001-12-21 2003-07-15 Gensci Orthobiologics, Inc. End-capped polyalkylene glycols and compositions containing such compounds
IL149562A0 (en) * 2002-05-09 2002-11-10 Prochon Ltd Fgf variants and methods for use thereof
US20050287135A1 (en) * 2002-05-17 2005-12-29 Wyeth Injectable solid hyaluronic acid carriers for delivery of osteogenic proteins
US7166574B2 (en) * 2002-08-20 2007-01-23 Biosurface Engineering Technologies, Inc. Synthetic heparin-binding growth factor analogs
US7981862B2 (en) 2003-08-19 2011-07-19 Biosurface Engineering Technologies, Inc. Composition comprising BMP-2 amplifier/co-activator for enhancement of osteogenesis
US7598224B2 (en) 2002-08-20 2009-10-06 Biosurface Engineering Technologies, Inc. Dual chain synthetic heparin-binding growth factor analogs
US8227411B2 (en) * 2002-08-20 2012-07-24 BioSurface Engineering Technologies, Incle FGF growth factor analogs
US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
DE60336002D1 (de) 2002-10-07 2011-03-24 Conformis Inc Minimal invasives gelenkimplantat mit einer den gelenkflächen angepassten dreidimensionalen geometrie
CN1780594A (zh) 2002-11-07 2006-05-31 康复米斯公司 用于确定半月板的大小和形状以及设计治疗的方法
BE1015258A5 (fr) 2002-12-18 2004-12-07 Dricot Roland Implant osseux.
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20050020506A1 (en) * 2003-07-25 2005-01-27 Drapeau Susan J. Crosslinked compositions comprising collagen and demineralized bone matrix, methods of making and methods of use
US7955616B2 (en) * 2003-09-23 2011-06-07 Orthocon, Inc. Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
US20080227696A1 (en) * 2005-02-22 2008-09-18 Biosurface Engineering Technologies, Inc. Single branch heparin-binding growth factor analogs
EP1725576B1 (en) * 2004-02-20 2010-09-22 Biosurface Engineering Technologies, Inc. Positive modulator of bone morphogenic protein-2
US20060194726A1 (en) * 2004-05-25 2006-08-31 Rueger David C Methods of treating cartilage defects
US20120077743A1 (en) * 2004-05-25 2012-03-29 Rueger David C Methods of treating cartilage defects
EP1763362B1 (en) * 2004-05-25 2011-07-06 Stryker Corporation Use of op-1 for treating cartilage defects
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
WO2006047279A2 (en) * 2004-10-21 2006-05-04 University Of Iowa Research Foundation In situ controlled release drug delivery system
US7951880B2 (en) * 2004-12-10 2011-05-31 University Of Iowa Research Foundation Compositions for breast implant filling and methods of use
US7270655B2 (en) * 2005-01-14 2007-09-18 Haidukewych George J Autologous material delivery apparatus and method
US7621963B2 (en) * 2005-04-13 2009-11-24 Ebi, Llc Composite bone graft material
US20060233849A1 (en) * 2005-04-13 2006-10-19 Simon Bruce J Composite bone graft material
WO2007001624A2 (en) * 2005-06-28 2007-01-04 Microchips, Inc. Medical and dental implant devices for controlled drug delivery
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
WO2007035778A2 (en) 2005-09-19 2007-03-29 Histogenics Corporation Cell-support matrix and a method for preparation thereof
JP5368102B2 (ja) * 2005-11-17 2013-12-18 バイオミメティック セラピューティクス, インコーポレイテッド rhPDGF−BB及び生体適合性マトリックスを用いた顎顔面骨強化
EP2671522A3 (en) 2006-02-06 2013-12-25 ConforMIS, Inc. Patient selectable joint arthroplasty devices and surgical tools
US8623026B2 (en) 2006-02-06 2014-01-07 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief
AU2007212273B2 (en) * 2006-02-09 2013-10-10 Stryker Corporation Compositions and methods for treating bone
US7771741B2 (en) * 2006-05-01 2010-08-10 Warsaw Orthopedic, Inc Demineralized bone matrix devices
US7838022B2 (en) 2006-05-01 2010-11-23 Warsaw Orthopedic, Inc Malleable implants containing demineralized bone matrix
US20100209470A1 (en) * 2006-05-01 2010-08-19 Warsaw Orthopedic, Inc. An Indiana Corporation Demineralized bone matrix devices
US8506983B2 (en) * 2006-05-01 2013-08-13 Warsaw Orthopedic, Inc. Bone filler material
CA2652549A1 (en) * 2006-05-17 2007-12-13 Stryker Corporation Use of a soluble morphogenic protein complex for treating cartilage defects
US7820172B1 (en) 2006-06-01 2010-10-26 Biosurface Engineering Technologies, Inc. Laminin-derived multi-domain peptides
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
US9642891B2 (en) 2006-06-30 2017-05-09 Biomimetic Therapeutics, Llc Compositions and methods for treating rotator cuff injuries
CA2658582C (en) * 2006-07-21 2013-12-10 Genera Doo Bmp-1 procollagen c-proteinase for diagnosis and treatment of bone and soft tissue defects and disorders
US20060287654A1 (en) * 2006-08-11 2006-12-21 Jeffrey Posnick Implant securing device and method
US8758819B2 (en) * 2006-09-13 2014-06-24 Enhance Skin Products, Inc. Cosmetic compositions for the treatment of skin and methods thereof
AU2007333425B2 (en) 2006-11-03 2014-03-27 Stryker Corporation Compositions and methods for arthrodetic procedures
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
AU2007339280B2 (en) * 2006-12-21 2013-12-05 Stryker Corporation Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents
US8178099B2 (en) 2006-12-29 2012-05-15 Osteogenex Inc. Methods of altering bone growth by administration of sost or wise antagonist or agonist
US20080195476A1 (en) * 2007-02-09 2008-08-14 Marchese Michael A Abandonment remarketing system
WO2008101300A1 (en) 2007-02-23 2008-08-28 Cellixe Pty Ltd Composition and method for the treatment or prevention of spinal disorders
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
AU2008255016B2 (en) * 2007-05-15 2013-05-09 Stryker Corporation Concentrated protein preparations of bone morphogenetic proteins and methods of use thereof
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
EP2187932B1 (en) 2007-08-07 2015-01-28 DePuy Synthes Products, LLC Protein formulations comprising gdf-5 in aqueous acidic solution
US9056150B2 (en) * 2007-12-04 2015-06-16 Warsaw Orthopedic, Inc. Compositions for treating bone defects
JP5864106B2 (ja) 2008-02-07 2016-02-17 バイオミメティック セラピューティクス, エルエルシー 仮骨延長のための組成物および方法
CA2717760C (en) * 2008-03-05 2016-03-29 Conformis, Inc. Edge-matched articular implant
WO2009111626A2 (en) 2008-03-05 2009-09-11 Conformis, Inc. Implants for altering wear patterns of articular surfaces
EP2265220A1 (en) 2008-03-05 2010-12-29 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US8840913B2 (en) * 2008-03-27 2014-09-23 Warsaw Orthopedic, Inc. Malleable multi-component implants and materials therefor
WO2009129101A1 (en) 2008-04-14 2009-10-22 Advanced Technologies And Regenerative Medicine, Llc Liquid buffered gdf-5 formulations
US8338170B2 (en) 2008-04-21 2012-12-25 Viacyte, Inc. Methods for purifying endoderm and pancreatic endoderm cells derived from human embryonic stem cells
DK2993226T3 (da) * 2008-06-03 2021-02-22 Viacyte Inc Vækstfaktorer til fremstilling af en definitiv endoderm
US20090298178A1 (en) * 2008-06-03 2009-12-03 D Amour Kevin Allen Growth factors for production of definitive endoderm
NZ602861A (en) 2008-09-09 2014-03-28 Biomimetic Therapeutics Llc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
US9017334B2 (en) 2009-02-24 2015-04-28 Microport Orthopedics Holdings Inc. Patient specific surgical guide locator and mount
US8808297B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
WO2010099231A2 (en) 2009-02-24 2010-09-02 Conformis, Inc. Automated systems for manufacturing patient-specific orthopedic implants and instrumentation
US8808303B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
US12383287B2 (en) 2009-02-24 2025-08-12 Microport Orthopedics Holdings, Inc. Systems and methods for installing an orthopedic implant
SG10201401326SA (en) 2009-04-16 2014-10-30 Conformis Inc Patient-specific joint arthroplasty devices for ligament repair
US20120294868A1 (en) 2009-04-24 2012-11-22 Edwards James R Anti-tgf-beta induction of bone cell function and bone growth
AU2010327987B2 (en) 2009-12-11 2015-04-02 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
US8492335B2 (en) 2010-02-22 2013-07-23 Biomimetic Therapeutics, Llc Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
EP2625264B1 (en) 2010-10-08 2022-12-07 Terumo BCT, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
CN103313733A (zh) 2010-11-15 2013-09-18 捷迈整形外科生物材料有限公司 骨空隙填充剂
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
SG193484A1 (en) 2011-02-15 2013-10-30 Conformis Inc Patent-adapted and improved articular implants, designs, surgical procedures and related guide tools
RU2633057C2 (ru) 2011-04-11 2017-10-11 Индьюс Байолоджикс Инк. Система и способ многофазного высвобождения факторов роста
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
US8992949B1 (en) 2011-11-17 2015-03-31 Unicare Biomedical, Inc. Biocompatible polymeric compositions having microcrystalline and amorphous components and methods for their manufacture
US9486226B2 (en) 2012-04-18 2016-11-08 Conformis, Inc. Tibial guides, tools, and techniques for resecting the tibial plateau
US9675471B2 (en) 2012-06-11 2017-06-13 Conformis, Inc. Devices, techniques and methods for assessing joint spacing, balancing soft tissues and obtaining desired kinematics for joint implant components
CN113416187B (zh) 2013-03-14 2024-07-19 奥斯菲治疗有限公司 促进骨生长的烷基胺骆驼蓬碱衍生物
MX2015011820A (es) * 2013-03-14 2016-01-25 Genzyme Corp Composiciones termosensibles para crecimiento oseo.
EP3068866B1 (en) 2013-11-16 2018-04-25 Terumo BCT, Inc. Expanding cells in a bioreactor
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CA2977625A1 (en) 2014-12-29 2016-07-07 Bioventus, Llc Systems and methods for improved delivery of osteoinductive molecules in bone repair
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
WO2016172026A1 (en) 2015-04-20 2016-10-27 The Board Of Regents Of The University Of Texas System Clec11a is a bone growth agent
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
CN110612344B (zh) 2017-03-31 2023-09-12 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
JP7235392B2 (ja) * 2017-05-30 2023-03-08 アクファー アイピー ビー.ヴィー. ポリ(1,3-トリメチレンカーボネート)を含む再吸収性の生分解性医療用及び化粧品組成物
JP7695496B2 (ja) 2018-08-14 2025-06-19 オシフィ セラピューティクス リミティド ライアビリティ カンパニー フルオロβ-カルボリン化合物
MX2021001752A (es) 2018-08-14 2021-06-23 Osteoqc Inc Compuestos de pirrolo-dipiridina.
US11324806B2 (en) 2018-10-19 2022-05-10 Warsaw Orthopedic, Inc. Sustained delivery of a growth differentiation factor
WO2020118011A1 (en) 2018-12-06 2020-06-11 Alexion Pharmaceuticals, Inc. Anti-alk2 antibodies and uses thereof
EP3975939B1 (en) 2019-05-29 2024-11-13 Wright Medical Technology, Inc. Device for preparing a tibia for receiving tibial implant component of a replacement ankle
EP4044941A4 (en) 2020-01-17 2023-11-15 Wright Medical Technology, Inc. GUIDANCE TOOLS, SYSTEMS AND METHODS
WO2022182430A1 (en) 2021-02-24 2022-09-01 Wright Medical Technology, Inc. Preparing a tibia for receiving tibial implant component of a replacement ankle
WO2022204315A1 (en) 2021-03-23 2022-09-29 Terumo Bct, Inc. Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60253455A (ja) 1984-05-28 1985-12-14 京セラ株式会社 骨形成因子を含有する生体材料とその製造方法
US4620327A (en) * 1984-07-05 1986-11-04 Caplan Arnold I Process of adapting soluble bone protein for use in stimulating osteoinduction
US6432919B1 (en) 1986-07-01 2002-08-13 Genetics Institute, Inc. Bone morphogenetic protein-3 and compositions
US5013649A (en) 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
IL83003A (en) 1986-07-01 1995-07-31 Genetics Inst Osteoinductive factors
NZ226170A (en) * 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor
US4863732A (en) * 1987-12-16 1989-09-05 Collagen Corporation Injectable composition for inductive bone repair
US5011691A (en) 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
US4968590A (en) 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
US5266683A (en) 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US5344654A (en) * 1988-04-08 1994-09-06 Stryker Corporation Prosthetic devices having enhanced osteogenic properties
ES2113857T3 (es) 1989-03-28 1998-05-16 Genetics Inst Composiciones osteoinductoras.
US5158934A (en) * 1989-09-01 1992-10-27 Genentech, Inc. Method of inducing bone growth using TGF-β
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5290271A (en) * 1990-05-14 1994-03-01 Jernberg Gary R Surgical implant and method for controlled release of chemotherapeutic agents
DK0536186T3 (da) 1990-05-16 2002-05-21 Genetics Inst Knogle- og brusk-dannelsesfremkaldende proteiner
AU666291B2 (en) 1990-06-15 1996-02-08 Carnegie Institution Of Washington Gdf-1
US5853746A (en) * 1991-01-31 1998-12-29 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
US5674844A (en) * 1991-03-11 1997-10-07 Creative Biomolecules, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US5693615A (en) * 1991-06-05 1997-12-02 The Procter & Gamble Company Therapeutic compositions for osteoinduction
BR9206110A (pt) * 1991-06-05 1995-07-11 Procter & Gamble Composições terapêuticas para osteoindução
US5661007A (en) 1991-06-25 1997-08-26 Genetics Institute, Inc. Bone morphogenetic protein-9 compositions
US6287816B1 (en) 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
EP0601135B1 (en) 1991-08-30 2005-11-02 Curis, Inc. Osteogenic proteins in the treatment of metabolic bone diseases
US5192743A (en) 1992-01-16 1993-03-09 Genentech, Inc. Reconstitutable lyophilized protein formulation
IL106278A0 (en) 1992-07-13 1993-11-15 Sumitomo Metal Ind Bone formation-inducing protein
WO1994006399A1 (en) 1992-09-15 1994-03-31 Creative Biomolecules, Inc. Morphogen-induced periodontal tissue regeneration
AU681362B2 (en) 1992-11-03 1997-08-28 Stryker Corporation OP-3-induced morphogenesis
DE4240621A1 (de) 1992-12-03 1994-06-09 Zahnradfabrik Friedrichshafen Verfahren zur Steuerung und Regelung der Lastübernahme bei einem automatischen Schaltgetriebe
DK0679097T3 (da) 1993-01-12 1997-12-22 Genentech Inc TGF-Beta-præparat til fremkaldelse af knoglevækst
WO1994015965A1 (en) 1993-01-12 1994-07-21 Johns Hopkins University School Of Medicine Growth differentiation factor-3
EP0698095B1 (en) 1993-05-12 2004-04-28 Genetics Institute, LLC Bmp-10 compositions
EP1398377A1 (en) 1993-07-09 2004-03-17 The John Hopkins University Growth differentation Factor-7
US5531791A (en) * 1993-07-23 1996-07-02 Bioscience Consultants Composition for repair of defects in osseous tissues, method of making, and prosthesis
WO1995006656A1 (en) 1993-09-03 1995-03-09 The Regents Of The University Of California Neural tissue affecting factor and compositions
US5385887A (en) * 1993-09-10 1995-01-31 Genetics Institute, Inc. Formulations for delivery of osteogenic proteins
EP1559726A3 (en) 1993-10-08 2006-01-25 The Johns Hopkins University School Of Medicine Growth differentiation factor-10
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
WO1995016635A1 (en) 1993-12-14 1995-06-22 E.I. Du Pont De Nemours And Company Recovery of spent catalyst
US5906827A (en) 1994-06-03 1999-05-25 Creative Biomolecules, Inc. Matrix for the manufacture of autogenous replacement body parts
ES2153564T3 (es) 1995-03-01 2001-03-01 Stryker Corp Regeneracion de la dentina inducida por un morfogeno.
EA000582B1 (ru) 1995-04-19 1999-12-29 Хехст Марион Руссел Лтд. Белок, соответствующий зрелому участку морфогенетического белка кости мр-52, фармацевтическая композиция для лечения заболеваний и дефектов хрящей и костей и способ получения белка
FI952196A0 (fi) 1995-05-08 1995-05-08 Suomen Punainen Risti Veripalv Framstaellning av immunoglobulin
ATE245996T1 (de) * 1995-06-05 2003-08-15 Inst Genetics Llc Verwendung von knochenmorphogeneseproteinen zur heilung und reparatur von bindegewebebefestigung
US5902785A (en) 1995-06-06 1999-05-11 Genetics Institute, Inc. Cartilage induction by bone morphogenetic proteins
US5674292A (en) * 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
JPH09143093A (ja) 1995-11-17 1997-06-03 Hoechst Japan Ltd 軟骨・骨誘導性修復用材料
US6048964A (en) * 1995-12-12 2000-04-11 Stryker Corporation Compositions and therapeutic methods using morphogenic proteins and stimulatory factors
US5752974A (en) 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
US5842477A (en) * 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
EP0910389A4 (en) 1996-03-05 2001-09-19 Orquest Inc METHOD FOR PROMOTING BONE GROWTH WITH HYALURONIC ACID AND GROWTH FACTORS
DE19647853A1 (de) 1996-11-19 1998-05-20 Bioph Biotech Entw Pharm Gmbh Verbindungen mit verbesserter knorpel- und/oder knocheninduzierender Aktivität
ATE302021T1 (de) 1997-01-30 2005-09-15 Bioph Biotech Entw Pharm Gmbh Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52
DE69814352T3 (de) * 1997-02-07 2009-08-13 Stryker Corp., Kalamazoo Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung
AU2002236558A1 (en) 2000-12-01 2002-06-11 Regents Of The University Of California Method and composition for modulating bone growth

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8546334B2 (en) 2001-11-19 2013-10-01 Scil Technology Gmbh Device having osteoinductive and osteoconductive properties
US7763270B2 (en) 2002-09-10 2010-07-27 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein
US8257728B2 (en) 2002-09-10 2012-09-04 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein

Similar Documents

Publication Publication Date Title
JP2000509635A5 (enExample)
JP2000509912A5 (enExample)
JP2000510751A5 (enExample)
JP2000509942A5 (enExample)
JP2000509637A5 (enExample)
JP2000507042A5 (enExample)
JP2001511042A5 (enExample)
JP2002501513A5 (enExample)
JP2000509587A5 (enExample)
JP2000507369A5 (enExample)
JP2000507433A5 (enExample)
JP2000508866A5 (enExample)
JP2000510793A5 (enExample)
JP2000508022A5 (enExample)
JP2000508680A5 (enExample)
JP2000509804A5 (enExample)
JP2000513868A5 (enExample)
JP2000509853A5 (enExample)
JP2000509755A5 (enExample)
JP2000510247A5 (enExample)
JP2000510969A5 (enExample)
JP2000508102A5 (enExample)
JP2000509818A5 (enExample)
JP2000509520A5 (enExample)
JP2000507434A5 (enExample)