JP2001509378A5 - - Google Patents

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Publication number
JP2001509378A5
JP2001509378A5 JP2000502165A JP2000502165A JP2001509378A5 JP 2001509378 A5 JP2001509378 A5 JP 2001509378A5 JP 2000502165 A JP2000502165 A JP 2000502165A JP 2000502165 A JP2000502165 A JP 2000502165A JP 2001509378 A5 JP2001509378 A5 JP 2001509378A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000502165A
Other languages
Japanese (ja)
Other versions
JP2001509378A (ja
JP4368522B2 (ja
Filing date
Publication date
Priority claimed from US08/891,789 external-priority patent/US6103466A/en
Application filed filed Critical
Priority claimed from PCT/IB1998/001197 external-priority patent/WO1999002667A1/en
Publication of JP2001509378A publication Critical patent/JP2001509378A/ja
Publication of JP2001509378A5 publication Critical patent/JP2001509378A5/ja
Application granted granted Critical
Publication of JP4368522B2 publication Critical patent/JP4368522B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2000502165A 1997-07-14 1998-07-14 哺乳動物におけるダブルマスル化を引き起こすミオスタチン遺伝子の変異 Expired - Lifetime JP4368522B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/891,789 US6103466A (en) 1997-07-14 1997-07-14 Double-muscling in mammals
US08/891,789 1997-07-14
US776198A 1998-01-15 1998-01-15
US09/007,761 1998-01-15
PCT/IB1998/001197 WO1999002667A1 (en) 1997-07-14 1998-07-14 Mutations in the myostation gene cause double-muscling in mammals

Publications (3)

Publication Number Publication Date
JP2001509378A JP2001509378A (ja) 2001-07-24
JP2001509378A5 true JP2001509378A5 (https=) 2005-12-22
JP4368522B2 JP4368522B2 (ja) 2009-11-18

Family

ID=26677351

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000502165A Expired - Lifetime JP4368522B2 (ja) 1997-07-14 1998-07-14 哺乳動物におけるダブルマスル化を引き起こすミオスタチン遺伝子の変異

Country Status (13)

Country Link
US (1) US20030129171A1 (https=)
EP (2) EP2045322B1 (https=)
JP (1) JP4368522B2 (https=)
AT (1) ATE442436T1 (https=)
AU (1) AU756620B2 (https=)
CA (1) CA2296434C (https=)
CY (1) CY1116682T1 (https=)
DE (1) DE69841139D1 (https=)
DK (1) DK2045322T3 (https=)
ES (1) ES2547858T3 (https=)
NZ (1) NZ502523A (https=)
PT (1) PT2045322E (https=)
WO (1) WO1999002667A1 (https=)

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US7320789B2 (en) 2001-09-26 2008-01-22 Wyeth Antibody inhibitors of GDF-8 and uses thereof
AR047392A1 (es) * 2002-10-22 2006-01-18 Wyeth Corp Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines
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US7468248B2 (en) 2002-12-31 2008-12-23 Cargill, Incorporated Methods and systems for inferring bovine traits
RU2322261C2 (ru) 2003-06-02 2008-04-20 Уайт Применение ингибиторов миостатика (gdf8) в сочетании с кортикостероидами для лечения нервно-мышечных заболеваний
EP1855694B1 (en) 2005-02-09 2020-12-02 Sarepta Therapeutics, Inc. Antisense composition for treating muscle atrophy
PL2407486T3 (pl) 2005-08-19 2018-05-30 Wyeth Llc Przeciwciała antagonistyczne względem GDF-8 i zastosowania w leczeniu ALS i innych zaburzeń związanych z GDF-8
KR100872042B1 (ko) * 2005-09-14 2008-12-05 주식회사 바이오리더스 마이오스타틴을 발현하는 세포표면 발현벡터 및 상기벡터에 의해 형질전환된 미생물
GB2433320B (en) * 2005-12-16 2009-10-07 Norwegian University Of Life S Diagnostic method
AU2006345724B2 (en) * 2006-06-30 2013-11-21 Lakewood-Amedex, Inc. Compositions and methods for the treatment of muscle wasting
KR100857861B1 (ko) * 2007-10-15 2008-09-11 주식회사 바이오리더스 Myo-2 펩타이드 중합체와 마이오스타틴의 융합단백질표면발현용 벡터 및 상기 벡터로 형질전환된 미생물
US9528124B2 (en) 2013-08-27 2016-12-27 Recombinetics, Inc. Efficient non-meiotic allele introgression
US10920242B2 (en) 2011-02-25 2021-02-16 Recombinetics, Inc. Non-meiotic allele introgression
MX363013B (es) * 2011-02-25 2019-03-04 Recombinetics Inc Animales genéticamente modificados y métodos para su obtención.
US20130085139A1 (en) 2011-10-04 2013-04-04 Royal Holloway And Bedford New College Oligomers
KR101704893B1 (ko) 2012-06-15 2017-02-08 화이자 인코포레이티드 Gdf-8에 대한 개선된 길항물질 항체 및 그의 용도
AR091482A1 (es) * 2012-06-21 2015-02-04 Recombinetics Inc Celulas modificadas geneticamente y metodos par su obtencion
RS61778B1 (sr) 2013-05-06 2021-06-30 Scholar Rock Inc Kompozicije i postupci za modulaciju faktora rasta
EP2960653A1 (en) * 2014-06-24 2015-12-30 Stichting Kwaliteitsgarantie Vleeskalversector Diagnostic kit and method for the identification of the manipulation of muscle mass in a domestic animal
MA41795A (fr) 2015-03-18 2018-01-23 Sarepta Therapeutics Inc Exclusion d'un exon induite par des composés antisens dans la myostatine
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CN106472430A (zh) * 2016-10-21 2017-03-08 延边朝鲜族自治州农业科学院(延边特产研究所) 一种寒冷地区烟蚜茧蜂冬季保种方法
CN110269867B (zh) * 2018-03-14 2022-06-21 必康生技(香港)有限公司 用于生物流体净化的组合物
CN110157818B (zh) * 2019-07-08 2023-04-25 云南东恒经贸集团猪育种有限公司 一种与猪眼肌高产性状相关的分子标记及其应用
GB2636643B (en) * 2020-12-03 2026-03-11 Lart Bio Co Ltd Transgenic animal having modified myostatin gene
CN120192396A (zh) * 2023-12-21 2025-06-24 江苏省农业科学院 一种肌肉生长抑制素mstn蛋白突变体及其制备方法和应用

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