JP2001507937A - 腫瘍壊死因子レセプター6αおよび腫瘍壊死因子レセプター6β - Google Patents

腫瘍壊死因子レセプター6αおよび腫瘍壊死因子レセプター6β

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Publication number
JP2001507937A
JP2001507937A JP53103798A JP53103798A JP2001507937A JP 2001507937 A JP2001507937 A JP 2001507937A JP 53103798 A JP53103798 A JP 53103798A JP 53103798 A JP53103798 A JP 53103798A JP 2001507937 A JP2001507937 A JP 2001507937A
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JP
Japan
Prior art keywords
tnfr
seq
sequence
polypeptide
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP53103798A
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English (en)
Japanese (ja)
Other versions
JP2001507937A5 (cg-RX-API-DMAC10.html
Inventor
エル. ゲンツ,ライナー
ニ,ジアン
エブナー,ラインハルト
ユ,グオ−リアン
エム. ルーベン,スティーブン
フェン,ピン
Original Assignee
ヒューマン ジノーム サイエンシーズ,インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21883066&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2001507937(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ヒューマン ジノーム サイエンシーズ,インコーポレイテッド filed Critical ヒューマン ジノーム サイエンシーズ,インコーポレイテッド
Publication of JP2001507937A publication Critical patent/JP2001507937A/ja
Publication of JP2001507937A5 publication Critical patent/JP2001507937A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP53103798A 1997-01-14 1998-01-13 腫瘍壊死因子レセプター6αおよび腫瘍壊死因子レセプター6β Withdrawn JP2001507937A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3549697P 1997-01-14 1997-01-14
US60/035,496 1997-01-14
PCT/US1998/000153 WO1998030694A2 (en) 1997-01-14 1998-01-13 TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b)

Publications (2)

Publication Number Publication Date
JP2001507937A true JP2001507937A (ja) 2001-06-19
JP2001507937A5 JP2001507937A5 (cg-RX-API-DMAC10.html) 2005-09-08

Family

ID=21883066

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53103798A Withdrawn JP2001507937A (ja) 1997-01-14 1998-01-13 腫瘍壊死因子レセプター6αおよび腫瘍壊死因子レセプター6β

Country Status (12)

Country Link
US (2) US8003386B1 (cg-RX-API-DMAC10.html)
EP (1) EP1007659B1 (cg-RX-API-DMAC10.html)
JP (1) JP2001507937A (cg-RX-API-DMAC10.html)
KR (1) KR20000070174A (cg-RX-API-DMAC10.html)
CN (1) CN1247567A (cg-RX-API-DMAC10.html)
AT (1) ATE365796T1 (cg-RX-API-DMAC10.html)
AU (1) AU729062C (cg-RX-API-DMAC10.html)
BR (1) BR9806954A (cg-RX-API-DMAC10.html)
CA (1) CA2277925A1 (cg-RX-API-DMAC10.html)
DE (1) DE69837996T2 (cg-RX-API-DMAC10.html)
ES (1) ES2286843T3 (cg-RX-API-DMAC10.html)
WO (1) WO1998030694A2 (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538176A (ja) * 2002-09-11 2005-12-15 ジェネンテック・インコーポレーテッド タンパク質精製

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7597886B2 (en) 1994-11-07 2009-10-06 Human Genome Sciences, Inc. Tumor necrosis factor-gamma
US7429646B1 (en) 1995-06-05 2008-09-30 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor-like 2
US7888466B2 (en) 1996-01-11 2011-02-15 Human Genome Sciences, Inc. Human G-protein chemokine receptor HSATU68
WO1997033904A1 (en) 1996-03-12 1997-09-18 Human Genome Sciences, Inc. Death domain containing receptors
US7357927B2 (en) 1996-03-12 2008-04-15 Human Genome Sciences, Inc. Death domain containing receptors
US6713061B1 (en) 1996-03-12 2004-03-30 Human Genome Sciences, Inc. Death domain containing receptors
US7964190B2 (en) 1996-03-22 2011-06-21 Human Genome Sciences, Inc. Methods and compositions for decreasing T-cell activity
US6635743B1 (en) 1996-03-22 2003-10-21 Human Genome Sciences, Inc. Apoptosis inducing molecule II and methods of use
US7285267B2 (en) 1997-01-14 2007-10-23 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6α & 6β
DE69837996T2 (de) 1997-01-14 2008-02-28 Human Genome Sciences, Inc. Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
WO1999004001A1 (en) * 1997-07-21 1999-01-28 Zymogenetics, Inc. Tumor necrosis factor receptor ztnfr-5
CA2299619A1 (en) * 1997-08-06 1999-02-18 Regeneron Pharmaceuticals, Inc. Human orphan receptor ntr-1
AU9376498A (en) * 1997-09-05 1999-03-22 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
WO1999014330A1 (en) * 1997-09-18 1999-03-25 Genentech, Inc. DcR3 POLYPEPTIDE, A TNFR HOMOLOG
WO1999026977A1 (en) * 1997-11-24 1999-06-03 Biogen, Inc. Novel receptors opg-2
EP1037908A2 (en) * 1997-12-16 2000-09-27 Incyte Pharmaceuticals, Inc. Human tumor necrosis factor-r2-like proteins
DE19809978A1 (de) * 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
HUP0102067A2 (hu) * 1998-03-30 2001-10-28 Eli Lilly And Co. A TNF receptorcsaládba tartozó érett FLINT (mFLINT) polipeptid vagy más néven az OPG3 terápiás alkalmazásai
US6916907B1 (en) 1998-10-23 2005-07-12 Curagen Corporation Nucleic acids encoding osteoprotegern-like proteins and methods of using same
AU2164400A (en) * 1998-12-09 2000-06-26 Eli Lilly And Company Flint compositions and uses thereof
EP1140138A2 (en) * 1998-12-22 2001-10-10 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2000046247A1 (en) * 1999-02-05 2000-08-10 Merck & Co., Inc. Methods of use for dna molecules encoding m68, a tnf receptor-related protein
WO2000050620A2 (en) 1999-02-26 2000-08-31 Human Genome Sciences, Inc. Human endokine alpha and methods of use
CA2362929A1 (en) * 1999-03-04 2000-09-08 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6.alpha. and 6.beta.
AU2495200A (en) * 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
US6965012B1 (en) * 1999-03-30 2005-11-15 Eli Lilly And Company Flint polypeptide analogs
CA2368760A1 (en) * 1999-03-30 2000-10-05 Eli Lilly And Company Flint polypeptide analogs
ES2291197T3 (es) * 1999-03-30 2008-03-01 Eli Lilly And Company Analogos de flint resistentes a proteasas.
US6835814B1 (en) 1999-03-30 2004-12-28 Eli Lilly And Company Protease resistant flint analogs
US6627199B1 (en) 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
WO2001010908A1 (en) 1999-08-04 2001-02-15 Amgen Inc. Ntr3, a member of the tnf-receptor supergene family
MXPA02001264A (es) 1999-08-04 2002-07-22 Amgen Inc Fhm, nuevo miembro de la familia de supergenes de ligando de factor de necrosis tumoral.
EP1214411A2 (en) * 1999-09-10 2002-06-19 Eli Lilly And Company Flint analog compounds and formulations thereof
AU7053000A (en) * 1999-09-10 2001-04-10 Eli Lilly And Company Flint compounds and formulations thereof
AU6891800A (en) * 1999-09-10 2001-04-10 Eli Lilly And Company Flint analog compounds and formulations thereof
EP1294949A4 (en) 2000-06-15 2004-08-25 Human Genome Sciences Inc HUMAN TUMORNESCROSE FACTOR DELTA AND EPSILON
AU2001268427B2 (en) 2000-06-16 2007-03-29 Glaxosmithkline Intellectual Property Limited Antibodies that immunospecifically bind to blys
CN1331125A (zh) * 2000-06-26 2002-01-16 上海博德基因开发有限公司 一种新的多肽——人含细胞色素c结构域的tnfr/ngfr蛋白9.02和编码这种多肽的多核苷酸
EP1322667A4 (en) * 2000-08-25 2004-08-18 Human Genome Sciences Inc TUMOR NECROSE FACTOR RECEPTORS 6-ALPHA AND 6-BETA
MXPA03010747A (es) 2001-05-25 2004-03-02 Human Genome Sciences Inc Anticuerpos que se unen inmunoespecificamente a receptores de ligando inductor de apoptosis relacionado con factor de necrosis tumoral.
CA2841097A1 (en) 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin and g-csf fusion proteins
KR20080074120A (ko) 2005-10-13 2008-08-12 휴먼 게놈 사이언시즈, 인코포레이티드 자가항체 양성 질환 환자의 치료에 유용한 방법 및 조성물
US20090269345A1 (en) * 2005-12-23 2009-10-29 Rong Fan CLN248 Antibody Compositions and Methods of Use
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
US9221895B2 (en) * 2009-03-13 2015-12-29 The Trustees Of The University Of Pennsylvania OX40/TRAIL fusion proteins
MX361929B (es) 2010-11-19 2018-12-19 Eisai R&D Man Co Ltd Star Anticuerpos anti-ligando de quimiocina cc 20 (ccl20) neutralizantes.
KR20240122922A (ko) 2013-03-27 2024-08-13 세다르스-신나이 메디칼 센터 Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전
CA2922704A1 (en) 2013-05-24 2014-11-27 Neil R. Cashman Cell senescence markers as diagnostic and therapeutic targets
EP3022295A4 (en) 2013-07-19 2017-03-01 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
CN109462996A (zh) 2016-03-17 2019-03-12 西达-赛奈医疗中心 通过rnaset2诊断炎性肠病的方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
CA2067031C (en) 1991-04-26 2003-02-18 Shigekazu Nagata Dna coding for human cell surface antigen
NZ275711A (en) 1993-10-14 1998-03-25 Immunex Corp Monoclonal antibodies and binding proteins which bind to human fas antigen (nerve growth factor/tumour necrosis factor receptor type)
US5830469A (en) 1993-10-14 1998-11-03 Immunex Corporation Fas antagonists and uses thereof
US5663070A (en) 1993-11-15 1997-09-02 Lxr Biotechnology Inc. Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
US5741667A (en) 1994-05-27 1998-04-21 Genentech, Inc. Tumor necrosis factor receptor-associated factors
US5632994A (en) 1994-06-14 1997-05-27 La Jolla Cancer Research Foundation Fas associated proteins
AU2363695A (en) 1995-04-27 1996-11-18 Human Genome Sciences, Inc. Human tumor necrosis factor receptors
US5985614A (en) * 1996-08-30 1999-11-16 Human Genome Sciences, Inc. Polynucleotides encoding interleukin-19
DE69837996T2 (de) 1997-01-14 2008-02-28 Human Genome Sciences, Inc. Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
US5885800A (en) 1997-02-04 1999-03-23 Smithkline Beecham Corporation DNA encoding tumor necrosis related receptor, TR4
CA2295991A1 (en) 1997-06-11 1998-12-17 Human Genome Sciences, Inc. Human tumor necrosis factor receptor tr9
WO1999004001A1 (en) 1997-07-21 1999-01-28 Zymogenetics, Inc. Tumor necrosis factor receptor ztnfr-5
CA2299619A1 (en) 1997-08-06 1999-02-18 Regeneron Pharmaceuticals, Inc. Human orphan receptor ntr-1
AU9376498A (en) 1997-09-05 1999-03-22 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
WO1999014330A1 (en) 1997-09-18 1999-03-25 Genentech, Inc. DcR3 POLYPEPTIDE, A TNFR HOMOLOG
WO1999026977A1 (en) 1997-11-24 1999-06-03 Biogen, Inc. Novel receptors opg-2
EP1037908A2 (en) 1997-12-16 2000-09-27 Incyte Pharmaceuticals, Inc. Human tumor necrosis factor-r2-like proteins
US6297367B1 (en) 1997-12-30 2001-10-02 Chiron Corporation Polynucleotide encoding TNFL1
AU2093499A (en) 1997-12-30 1999-07-19 Chiron Corporation Members of tnf and tnfr families
DE19809978A1 (de) 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
HUP0102067A2 (hu) 1998-03-30 2001-10-28 Eli Lilly And Co. A TNF receptorcsaládba tartozó érett FLINT (mFLINT) polipeptid vagy más néven az OPG3 terápiás alkalmazásai
EP1093516A2 (en) 1998-07-06 2001-04-25 Schering Corporation Mammalian genes; dendritic cell prostaglandin-like transporter (dc-pgt), hdtea84, hsljd37r and rankl, hcc5 chemokine, deubiquitinating 11 and 12 (dub11, dub12), md-1, md2 and cyclin e2, related reagents and methods
KR100529270B1 (ko) 1998-12-01 2005-11-21 제넨테크, 인크. 혈관신생 및 심혈관형성의 촉진 또는 억제
AU2164400A (en) 1998-12-09 2000-06-26 Eli Lilly And Company Flint compositions and uses thereof
EP1140138A2 (en) 1998-12-22 2001-10-10 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2000046247A1 (en) 1999-02-05 2000-08-10 Merck & Co., Inc. Methods of use for dna molecules encoding m68, a tnf receptor-related protein
CA2362929A1 (en) 1999-03-04 2000-09-08 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6.alpha. and 6.beta.
AU2495200A (en) 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
KR20010103046A (ko) 1999-03-08 2001-11-17 제넨테크, 인크. 면역 관련 질환 치료용 조성물 및 치료 방법
CA2367315A1 (en) 1999-03-11 2000-09-14 Human Genome Sciences, Inc. Apoptosis inducing molecule ii and methods of use
ES2291197T3 (es) 1999-03-30 2008-03-01 Eli Lilly And Company Analogos de flint resistentes a proteasas.
CA2368760A1 (en) 1999-03-30 2000-10-05 Eli Lilly And Company Flint polypeptide analogs
CA2384713A1 (en) 1999-09-29 2001-04-05 Human Genome Sciences, Inc. Colon and colon cancer associated polynucleotides and polypeptides
AU1189101A (en) 1999-10-20 2001-04-30 Eli Lilly And Company Therapeutic applications of flint polypeptides
AU1915201A (en) 1999-12-07 2001-06-18 Eli Lilly And Company Improving stability of flint through o-linked glycosylation
WO2001042434A1 (en) 1999-12-09 2001-06-14 Merck & Co., Inc. Dna molecules encoding human nhl, a dna helicase
WO2001068912A2 (en) 2000-03-15 2001-09-20 Epigenomics Ag Diagnosis of diseases associated with tumor suppressor genes and oncogenes
AU2001266787A1 (en) 2000-06-07 2002-01-08 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
AU2001276371A1 (en) 2000-06-30 2002-01-14 Epigenomics Ag Method and nucleic acids for analysing the methylation of genes implicated pharmacogenomics
WO2002009668A2 (en) 2000-08-02 2002-02-07 Eli Lilly And Company Pulmonary administration of flint
WO2002060317A2 (en) 2001-01-30 2002-08-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of pancreatic cancer
JP2005506282A (ja) 2001-02-01 2005-03-03 イーライ・リリー・アンド・カンパニー Flintグリコフォーム
WO2002060947A2 (en) 2001-02-01 2002-08-08 Eli Lilly And Company Glycoforms a fas ligand inhibitory protein analog
US20040236091A1 (en) 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
FR2908832B1 (fr) 2006-11-20 2011-08-26 Valeo Systemes Thermiques Carter pour echangeur de chaleur

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538176A (ja) * 2002-09-11 2005-12-15 ジェネンテック・インコーポレーテッド タンパク質精製
JP2019043953A (ja) * 2002-09-11 2019-03-22 ジェネンテック, インコーポレイテッド タンパク質精製
JP2021138769A (ja) * 2002-09-11 2021-09-16 ジェネンテック, インコーポレイテッド タンパク質精製

Also Published As

Publication number Publication date
ATE365796T1 (de) 2007-07-15
CN1247567A (zh) 2000-03-15
DE69837996T2 (de) 2008-02-28
BR9806954A (pt) 2000-03-21
EP1007659B1 (en) 2007-06-27
CA2277925A1 (en) 1998-07-16
KR20000070174A (ko) 2000-11-25
AU5815798A (en) 1998-08-03
AU729062C (en) 2004-03-25
AU729062B2 (en) 2001-01-25
EP1007659A2 (en) 2000-06-14
WO1998030694A3 (en) 1998-11-12
DE69837996D1 (de) 2007-08-09
US7186800B1 (en) 2007-03-06
ES2286843T3 (es) 2007-12-01
US8003386B1 (en) 2011-08-23
WO1998030694A2 (en) 1998-07-16

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